Frontotemporal dementia mutant Tau promotes aberrant Fyn nanoclustering in hippocampal dendritic spines

Need for speed: Super-resolving the dynamic nanoclustering of syntaxin-1 at exocytic fusion sites

(2019) Pranesh Padmanabhan et al.   NEUROPHARMACOLOGY

Multistep Track Segmentation and Motion Classification for Transient Mobility Analysis

(2018) Anthony R. Vega et al.   BIOPHYSICAL JOURNAL

Pyk2 is a Novel Tau Tyrosine Kinase that is Regulated by the Tyrosine Kinase Fyn

(2018) Chuanzhou Li et al.   JOURNAL OF ALZHEIMERS DISEASE

Synaptic nanomodules underlie the organization and plasticity of spine synapses

(2018) Martin Hruska et al.   NATURE NEUROSCIENCE

Clustering on Membranes: Fluctuations and More

(2018) Ludger Johannes et al.   TRENDS IN CELL BIOLOGY

Differential Nanoscale Topography and Functional Role of GluN2-NMDA Receptor Subtypes at Glutamatergic Synapses

(2018) Blanka Kellermayer et al.   NEURON

Disease‐associated tau impairs mitophagy by inhibiting Parkin translocation to mitochondria

(2018) Nadia Cummins et al.   EMBO JOURNAL

Activity-Dependent Netrin-1 Secretion Drives Synaptic Insertion of GluA1-Containing AMPA Receptors in the Hippocampus

(2018) Stephen D. Glasgow et al.   Cell Reports

Visualizing endocytic recycling and trafficking in live neurons by subdiffractional tracking of internalized molecules

(2017) Merja Joensuu et al.   Nature Protocols

Erratum: In vivo single-molecule imaging of syntaxin1A reveals polyphosphoinositide- and activity-dependent trapping in presynaptic nanoclusters

(2017) Adekunle T. Bademosi et al.   Nature Communications

Tau association with synaptic vesicles causes presynaptic dysfunction

(2017) Lujia Zhou et al.   Nature Communications

SharpViSu: integrated analysis and segmentation of super-resolution microscopy data

(2016) Leonid Andronov et al.   BIOINFORMATICS

Tauopathy induced by low level expression of a human brain-derived tau fragment in mice is rescued by phenylbutyrate

(2016) Marie K. Bondulich et al.   BRAIN

Subdiffractional tracking of internalized molecules reveals heterogeneous motion states of synaptic vesicles

(2016) Merja Joensuu et al.   JOURNAL OF CELL BIOLOGY

The Munc18-1 domain 3a hinge-loop controls syntaxin-1A nanodomain assembly and engagement with the SNARE complex during secretory vesicle priming

(2016) Ravikiran Kasula et al.   JOURNAL OF CELL BIOLOGY

Ligand-induced growth and compaction of CD36 nanoclusters enriched in Fyn induces Fyn signaling

(2016) John Maringa Githaka et al.   JOURNAL OF CELL SCIENCE

Protein Crowding within the Postsynaptic Density Can Impede the Escape of Membrane Proteins

(2016) T. P. Li et al.   JOURNAL OF NEUROSCIENCE

Caspase-2 cleavage of tau reversibly impairs memory

(2016) Xiaohui Zhao et al.   NATURE MEDICINE

PSD-95 stabilizes NMDA receptors by inducing the degradation of STEP61

(2016) Sehoon Won et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mapping the dynamics and nanoscale organization of synaptic adhesion proteins using monomeric streptavidin

(2016) Ingrid Chamma et al.   Nature Communications

Fyn inhibition rescues established memory and synapse loss in Alzheimer mice

(2015) Adam C. Kaufman et al.   ANNALS OF NEUROLOGY

Pseudophosphorylation of Tau at distinct epitopes or the presence of the P301L mutation targets the microtubule-associated protein Tau to dendritic spines

(2015) Di Xia et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

SR-Tesseler: a method to segment and quantify localization-based super-resolution microscopy data

(2015) Florian Levet et al.   NATURE METHODS

Biochemical Computation for Spine Structural Plasticity

(2015) Jun Nishiyama et al.   NEURON

Glutamate-Induced AMPA Receptor Desensitization Increases Their Mobility and Modulates Short-Term Plasticity through Unbinding from Stargazin

(2015) Audrey Constals et al.   NEURON

Concentration- and chromosome-organization-dependent regulator unbinding from DNA for transcription regulation in living cells

(2015) Tai-Yen Chen et al.   Nature Communications

Organization and dynamics of SNARE proteins in the presynaptic membrane

(2015) Dragomir Milovanovic et al.   Frontiers in Physiology

Residence Times of Receptors in Dendritic Spines Analyzed by Stochastic Simulations in Empirical Domains

(2014) Nathanael Hoze et al.   BIOPHYSICAL JOURNAL

Multiple Spatial and Kinetic Subpopulations of CaMKII in Spines and Dendrites as Resolved by Single-Molecule Tracking PALM

(2014) H. E. Lu et al.   JOURNAL OF NEUROSCIENCE

Single-molecule tracking of tau reveals fast kiss-and-hop interaction with microtubules in living neurons

(2014) Dennis Janning et al.   MOLECULAR BIOLOGY OF THE CELL

Enhanced synapse remodelling as a common phenotype in mouse models of autism

(2014) Masaaki Isshiki et al.   Nature Communications

Premature lethality, hyperactivity, and aberrant phosphorylation in transgenic mice expressing a constitutively active form of Fyn

(2014) Di Xia et al.   Frontiers in Molecular Neuroscience

SEMA3A Signaling Controls Layer-Specific Interneuron Branching in the Cerebellum

(2013) Jean-Michel Cioni et al.   CURRENT BIOLOGY

Super-Resolution Imaging Reveals That AMPA Receptors Inside Synapses Are Dynamically Organized in Nanodomains Regulated by PSD95

(2013) D. Nair et al.   JOURNAL OF NEUROSCIENCE

Metabotropic Glutamate Receptor 5 Is a Coreceptor for Alzheimer Aβ Oligomer Bound to Cellular Prion Protein

(2013) Ji Won Um et al.   NEURON

Real-Time Analysis and Visualization for Single-Molecule Based Super-Resolution Microscopy

(2013) Adel Kechkar et al.   PLoS One

Real-Time Dynamics of RNA Polymerase II Clustering in Live Human Cells

(2013) I. I. Cisse et al.   SCIENCE

The Complex PrPc-Fyn Couples Human Oligomeric A  with Pathological Tau Changes in Alzheimer's Disease

(2012) M. Larson et al.   JOURNAL OF NEUROSCIENCE

Conformational states of the kinase Lck regulate clustering in early T cell signaling

(2012) Jérémie Rossy et al.   NATURE IMMUNOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons

(2012) Ji Won Um et al.   NATURE NEUROSCIENCE

Wavelet analysis for single molecule localization microscopy

(2012) I. Izeddin et al.   OPTICS EXPRESS

Heterogeneity of AMPA receptor trafficking and molecular interactions revealed by superresolution analysis of live cell imaging

(2012) N. Hoze et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane mechanisms for signal transduction: The coupling of the meso-scale raft domains to membrane-skeleton-induced compartments and dynamic protein complexes

(2012) Akihiro Kusumi et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Tyrosine phosphorylation of tau regulates its interactions with Fyn SH2 domains, but not SH3 domains, altering the cellular localization of tau

(2011) Alessia Usardi et al.   FEBS Journal

Src family kinases: modulators of neurotransmitter receptor function and behavior

(2011) Hiroshi Ohnishi et al.   TRENDS IN NEUROSCIENCES

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

(2010) Lars M. Ittner et al.   CELL

Fyn-Tau-Amyloid: A Toxic Triad

(2010) Christian Haass et al.   CELL

The impacts of geometry and binding on CaMKII diffusion and retention in dendritic spines

(2010) Michael J. Byrne et al.   JOURNAL OF COMPUTATIONAL NEUROSCIENCE

Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease

(2010) Lars M. Ittner et al.   NATURE REVIEWS NEUROSCIENCE

Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration

(2010) Brian R. Hoover et al.   NEURON

Differential trafficking of Src, Lyn, Yes and Fyn is specified by the state of palmitoylation in the SH4 domain

(2009) I. Sato et al.   JOURNAL OF CELL SCIENCE

Primary support cultures of hippocampal and substantia nigra neurons

(2009) Thomas Fath et al.   Nature Protocols

Using plasma membrane nanoclusters to build better signaling circuits

(2008) Angus S. Harding et al.   TRENDS IN CELL BIOLOGY