In vivo single-molecule imaging of syntaxin1A reveals polyphosphoinositide- and activity-dependent trapping in presynaptic nanoclusters

Calcium Promotes the Formation of Syntaxin 1 Mesoscale Domains through Phosphatidylinositol 4,5-Bisphosphate

(2016) Dragomir Milovanovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Botulinum neurotoxin type-A enters a non-recycling pool of synaptic vesicles

(2016) Callista B. Harper et al.   Scientific Reports

Behavioral and electrophysiological analysis of general anesthesia in 3 background strains ofDrosophila melanogaster

(2015) Oressia Zalucki et al.   FLY

Mechanistic insights into the recycling machine of the SNARE complex

(2015) Minglei Zhao et al.   NATURE

Mobility of Calcium Channels in the Presynaptic Membrane

(2015) Romy Schneider et al.   NEURON

Glutamate-Induced AMPA Receptor Desensitization Increases Their Mobility and Modulates Short-Term Plasticity through Unbinding from Stargazin

(2015) Audrey Constals et al.   NEURON

Hydrophobic mismatch sorts SNARE proteins into distinct membrane domains

(2015) Dragomir Milovanovic et al.   Nature Communications

Activity-driven relaxation of the cortical actomyosin II network synchronizes Munc18-1-dependent neurosecretory vesicle docking

(2015) Andreas Papadopulos et al.   Nature Communications

Dynamical Organization of Syntaxin-1A at the Presynaptic Active Zone

(2015) Alexander Ullrich et al.   PLoS Computational Biology

Single Particle Tracking Reveals that EGFR Signaling Activity Is Amplified in Clathrin-Coated Pits

(2015) Jenny Ibach et al.   PLoS One

Independent optical excitation of distinct neural populations

(2014) Nathan C Klapoetke et al.   NATURE METHODS

Contact-induced clustering of syntaxin and munc18 docks secretory granules at the exocytosis site

(2014) Nikhil R. Gandasi et al.   Nature Communications

In vivo single-molecule imaging identifies altered dynamics of calcium channels in dystrophin-mutant C. elegans

(2014) Hong Zhan et al.   Nature Communications

Increased Polyubiquitination and Proteasomal Degradation of a Munc18-1 Disease-Linked Mutant Causes Temperature-Sensitive Defect in Exocytosis

(2014) Sally Martin et al.   Cell Reports

Myosin VI small insert isoform maintains exocytosis by tethering secretory granules to the cortical actin

(2013) Vanesa M. Tomatis et al.   JOURNAL OF CELL BIOLOGY

The Munc18-1 domain 3a loop is essential for neuroexocytosis but not for syntaxin-1A transport to the plasma membrane

(2013) S. Martin et al.   JOURNAL OF CELL SCIENCE

Extracting intracellular diffusive states and transition rates from single-molecule tracking data

(2013) Fredrik Persson et al.   NATURE METHODS

Synaptic PI(3,4,5)P3 Is Required for Syntaxin1A Clustering and Neurotransmitter Release

(2013) Thang Manh Khuong et al.   NEURON

Super-resolution Imaging Reveals the Internal Architecture of Nano-sized Syntaxin Clusters

(2012) Dana Bar-On et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rational design of true monomeric and bright photoactivatable fluorescent proteins

(2012) Mingshu Zhang et al.   NATURE METHODS

Correlation Functions Quantify Super-Resolution Images and Estimate Apparent Clustering Due to Over-Counting

(2012) Sarah L. Veatch et al.   PLoS One

Molecular Mechanism of Cholesterol- and Polyphosphoinositide-Mediated Syntaxin Clustering

(2011) David H. Murray et al.   BIOCHEMISTRY

Syntaxin1A Lateral Diffusion Reveals Transient and Local SNARE Interactions

(2011) C. Ribrault et al.   JOURNAL OF NEUROSCIENCE

Membrane protein sequestering by ionic protein–lipid interactions

(2011) Geert van den Bogaart et al.   NATURE

Pre-existing clusters of the adaptor Lat do not participate in early T cell signaling events

(2011) David J Williamson et al.   NATURE IMMUNOLOGY

Probing protein heterogeneity in the plasma membrane using PALM and pair correlation analysis

(2011) Prabuddha Sengupta et al.   NATURE METHODS

Systematic Mutational Analysis of the Intracellular Regions of Yeast Gap1 Permease

(2011) Ahmad Merhi et al.   PLoS One

Synaptic Vesicle Exocytosis

(2011) T. C. Sudhof et al.   Cold Spring Harbor Perspectives in Biology

Phosphatidylinositol(4,5)bisphosphate coordinates actin-mediated mobilization and translocation of secretory vesicles to the plasma membrane of chromaffin cells

(2011) Peter J. Wen et al.   Nature Communications

PALM imaging and cluster analysis of protein heterogeneity at the cell surface

(2010) Dylan M. Owen et al.   Journal of Biophotonics

Syntaxin clusters assemble reversibly at sites of secretory granules in live cells

(2010) S. Barg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single secretory granules of live cells recruit syntaxin-1 and synaptosomal associated protein 25 (SNAP-25) in large copy numbers

(2010) M. K. Knowles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clustering of Syntaxin-1A in Model Membranes Is Modulated by Phosphatidylinositol 4,5-Bisphosphate and Cholesterol

(2009) David H. Murray et al.   BIOCHEMISTRY

Synaptotagmin-1 Docks Secretory Vesicles to Syntaxin-1/SNAP-25 Acceptor Complexes

(2009) Heidi de Wit et al.   CELL

Genomic mapping and expression patterns of C380, OK6 and D42 enhancer trap lines in the larval nervous system of Drosophila

(2009) Subhabrata Sanyal   GENE EXPRESSION PATTERNS

Abrogating Munc18-1-SNARE Complex Interaction Has Limited Impact on Exocytosis in PC12 Cells

(2009) Nancy T. Malintan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A bright and photostable photoconvertible fluorescent protein

(2009) Sean A McKinney et al.   NATURE METHODS

An internal thermal sensor controlling temperature preference in Drosophila

(2008) Fumika N. Hamada et al.   NATURE

High-density mapping of single-molecule trajectories with photoactivated localization microscopy

(2008) Suliana Manley et al.   NATURE METHODS