Antitumour dendritic cell vaccination in a priming and boosting approach

Proteogenomics Uncovers a Vast Repertoire of Shared Tumor-Specific Antigens in Ovarian Cancer

(2020) Qingchuan Zhao et al.   Cancer Immunology Research

Biotechnologies to tackle the challenge of neoantigen identification

(2020) Marion Arnaud et al.   CURRENT OPINION IN BIOTECHNOLOGY

Human Dendritic Cells: Their Heterogeneity and Clinical Application Potential in Cancer Immunotherapy

(2019) Thiago A. Patente et al.   Frontiers in Immunology

On the Other Side: Manipulating the Immune Checkpoint Landscape of Dendritic Cells to Enhance Cancer Immunotherapy

(2019) Benjamin Y. Kong et al.   Frontiers in Oncology

Neoantigen identification strategies enable personalized immunotherapy in refractory solid tumors

(2019) Fangjun Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Immunogenic neoantigens derived from gene fusions stimulate T cell responses

(2019) Wei Yang et al.   NATURE MEDICINE

Prognostic value of tumor-infiltrating lymphocytes in melanoma: a systematic review and meta-analysis

(2019) Qiaofen Fu et al.   OncoImmunology

The clinical application of cancer immunotherapy based on naturally circulating dendritic cells

(2019) Kalijn F. Bol et al.   Journal for ImmunoTherapy of Cancer

Immunology of Plasmacytoid Dendritic Cells in Solid Tumors: A Brief Review

(2019) Vladimír Koucký et al.   Cancers

Determinants for Neoantigen Identification

(2019) Andrea Garcia-Garijo et al.   Frontiers in Immunology

UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma

(2019) Yochai Wolf et al.   CELL

LTR retroelement expansion of the human cancer transcriptome and immunopeptidome revealed by de novo transcript assembly

(2019) Jan Attig et al.   GENOME RESEARCH

Defining HLA-II Ligand Processing and Binding Rules with Mass Spectrometry Enhances Cancer Epitope Prediction

(2019) Jennifer G. Abelin et al.   IMMUNITY

Sensitive Detection and Analysis of Neoantigen-Specific T Cell Populations from Tumors and Blood

(2019) Songming Peng et al.   Cell Reports

Cryoablation and Immunotherapy: An Enthralling Synergy to Confront the Tumors

(2019) Chakradhar Yakkala et al.   Frontiers in Immunology

A Phase Ib Study of the Combination of Personalized Autologous Dendritic Cell Vaccine, Aspirin, and Standard of Care Adjuvant Chemotherapy Followed by Nivolumab for Resected Pancreatic Adenocarcinoma—A Proof of Antigen Discovery Feasibility in Three Patients

(2019) Michal Bassani-Sternberg et al.   Frontiers in Immunology

Biomaterial-based platforms for in situ dendritic cell programming and their use in antitumor immunotherapy

(2019) João Calmeiro et al.   Journal for ImmunoTherapy of Cancer

A Phase I/II trial comparing autologous dendritic cell vaccine pulsed either with personalized peptides (PEP-DC) or with tumor lysate (OC-DC) in patients with advanced high-grade ovarian serous carcinoma

(2019) Apostolos Sarivalasis et al.   Journal of Translational Medicine

MHC-II neoantigens shape tumour immunity and response to immunotherapy

(2019) Elise Alspach et al.   NATURE

Predicting HLA class II antigen presentation through integrated deep learning

(2019) Binbin Chen et al.   NATURE BIOTECHNOLOGY

Robust prediction of HLA class II epitopes by deep motif deconvolution of immunopeptidomes

(2019) Julien Racle et al.   NATURE BIOTECHNOLOGY

Developing neoantigen-targeted T cell–based treatments for solid tumors

(2019) Tori N. Yamamoto et al.   NATURE MEDICINE

Engineering dendritic cell vaccines to improve cancer immunotherapy

(2019) Caleb R. Perez et al.   Nature Communications

Immunotherapy Based on Dendritic Cell-Targeted/-Derived Extracellular Vesicles—A Novel Strategy for Enhancement of the Anti-tumor Immune Response

(2019) Oleg Markov et al.   Frontiers in Pharmacology

Blood-derived dendritic cell vaccinations induce immune responses that correlate with clinical outcome in patients with chemo-naive castration-resistant prostate cancer

(2019) Harm Westdorp et al.   Journal for ImmunoTherapy of Cancer

Combined immunotherapy encompassing intratumoral poly-ICLC, dendritic-cell vaccination and radiotherapy in advanced cancer patients

(2018) M E Rodríguez-Ruiz et al.   ANNALS OF ONCOLOGY

Immunogenic chemotherapy: Dose and schedule dependence and combination with immunotherapy

(2018) Junjie Wu et al.   CANCER LETTERS

Human dendritic cell subsets: an update

(2018) Matthew Collin et al.   IMMUNOLOGY

Molecular Determinants of Response to Anti–Programmed Cell Death (PD)-1 and Anti–Programmed Death-Ligand 1 (PD-L1) Blockade in Patients With Non–Small-Cell Lung Cancer Profiled With Targeted Next-Generation Sequencing

(2018) Hira Rizvi et al.   JOURNAL OF CLINICAL ONCOLOGY

Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer

(2018) Nikolaos Zacharakis et al.   NATURE MEDICINE

The C-terminal extension landscape of naturally presented HLA-I ligands

(2018) Philippe Guillaume et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Personalized cancer vaccine effectively mobilizes antitumor T cell immunity in ovarian cancer

(2018) Janos L. Tanyi et al.   Science Translational Medicine

The Abscopal Effect in the Era of Cancer Immunotherapy: a Spontaneous Synergism Boosting Anti-tumor Immunity?

(2018) Zuzana Hlavata et al.   Targeted Oncology

Initial phase I/IIa trial results of an autologous tumor lysate, particle-loaded, dendritic cell (TLPLDC) vaccine in patients with solid tumors

(2018) Garth S. Herbert et al.   VACCINE

In situ vaccination: Harvesting low hanging fruit on the cancer immunotherapy tree

(2018) Mee Rie Sheen et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Co-expression of CD39 and CD103 identifies tumor-reactive CD8 T cells in human solid tumors

(2018) Thomas Duhen et al.   Nature Communications

Sensitive and frequent identification of high avidity neo-epitope specific CD8+ T cells in immunotherapy-naive ovarian cancer

(2018) Sara Bobisse et al.   Nature Communications

Immune Response Generated With the Administration of Autologous Dendritic Cells Pulsed With an Allogenic Tumoral Cell-Lines Lysate in Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma

(2018) Daniel Benitez-Ribas et al.   Frontiers in Oncology

Towards superior dendritic-cell vaccines for cancer therapy

(2018) Mansi Saxena et al.   Nature Biomedical Engineering

Combining radiation therapy and cancer immune therapies: From preclinical findings to clinical applications

(2018) S. Bockel et al.   Cancer Radiotherapie

50 Gy Stereotactic Body Radiation Therapy to the Dominant Intra-Prostatic Nodule: Results from a Phase Ia/b Trial

(2018) Fernanda G. Herrera et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Intron retention is a source of neoepitopes in cancer

(2018) Alicia C Smart et al.   NATURE BIOTECHNOLOGY

Predicting Antigen Presentation—What Could We Learn From a Million Peptides?

(2018) David Gfeller et al.   Frontiers in Immunology

Development of tumor mutation burden as an immunotherapy biomarker: utility for the oncology clinic

(2018) T A Chan et al.   ANNALS OF ONCOLOGY

An autologous dendritic cell vaccine polarizes a Th-1 response which is tumoricidal to patient-derived breast cancer cells

(2018) Michele Tomasicchio et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

In vivo cancer vaccination: Which dendritic cells to target and how?

(2018) Cheryl Lai-Lai Chiang et al.   CANCER TREATMENT REVIEWS

Actively personalized vaccination trial for newly diagnosed glioblastoma

(2018) Norbert Hilf et al.   NATURE

Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial

(2018) Derin B. Keskin et al.   NATURE

High-throughput determination of the antigen specificities of T cell receptors in single cells

(2018) Shu-Qi Zhang et al.   NATURE BIOTECHNOLOGY

Low and variable tumor reactivity of the intratumoral TCR repertoire in human cancers

(2018) Wouter Scheper et al.   NATURE MEDICINE

Noncoding regions are the main source of targetable tumor-specific antigens

(2018) Céline M. Laumont et al.   Science Translational Medicine

Rejection of immunogenic tumor clones is limited by clonal fraction

(2018) Ron S Gejman et al.   eLife

Dendritic Cell Cancer Therapy: Vaccinating the Right Patient at the Right Time

(2018) Wouter W. van Willigen et al.   Frontiers in Immunology

Audencel Immunotherapy Based on Dendritic Cells Has No Effect on Overall and Progression-Free Survival in Newly Diagnosed Glioblastoma: A Phase II Randomized Trial

(2018) Johanna Buchroithner et al.   Cancers

Mass Spectrometry Profiling of HLA-Associated Peptidomes in Mono-allelic Cells Enables More Accurate Epitope Prediction

(2017) Jennifer G. Abelin et al.   IMMUNITY

In silicoand cell-based analyses reveal strong divergence between prediction and observation of T-cell–recognized tumor antigen T-cell epitopes

(2017) Julien Schmidt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NetMHCpan-4.0: Improved Peptide–MHC Class I Interaction Predictions Integrating Eluted Ligand and Peptide Binding Affinity Data

(2017) Vanessa Jurtz et al.   JOURNAL OF IMMUNOLOGY

The era of bioengineering: how will this affect the next generation of cancer immunotherapy?

(2017) Michele Graciotti et al.   Journal of Translational Medicine

A phase II trial of autologous dendritic cell vaccination and radiochemotherapy following fluorescence-guided surgery in newly diagnosed glioblastoma patients

(2017) Susana Inogés et al.   Journal of Translational Medicine

Tumor Mutational Burden as an Independent Predictor of Response to Immunotherapy in Diverse Cancers

(2017) Aaron M. Goodman et al.   MOLECULAR CANCER THERAPEUTICS

Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer

(2017) Ugur Sahin et al.   NATURE

An immunogenic personal neoantigen vaccine for patients with melanoma

(2017) Patrick A. Ott et al.   NATURE

Tracking the Evolution of Non–Small-Cell Lung Cancer

(2017) Mariam Jamal-Hanjani et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tumor Mutational Burden and Response Rate to PD-1 Inhibition

(2017) Mark Yarchoan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Integrating Next-Generation Dendritic Cell Vaccines into the Current Cancer Immunotherapy Landscape

(2017) Abhishek D. Garg et al.   TRENDS IN IMMUNOLOGY

Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma

(2017) Martin Lauss et al.   Nature Communications

Deciphering HLA-I motifs across HLA peptidomes improves neo-antigen predictions and identifies allostery regulating HLA specificity

(2017) Michal Bassani-Sternberg et al.   PLoS Computational Biology

Human Tumor Antigens Yesterday, Today, and Tomorrow

(2017) Olivera J. Finn   Cancer Immunology Research

Selection of Shared and Neoantigen-Reactive T Cells for Adoptive Cell Therapy Based on CD137 Separation

(2017) Sivan Seliktar-Ofir et al.   Frontiers in Immunology

An Analysis of Natural T Cell Responses to Predicted Tumor Neoepitopes

(2017) Anne-Mette Bjerregaard et al.   Frontiers in Immunology

‘Hotspots’ of Antigen Presentation Revealed by Human Leukocyte Antigen Ligandomics for Neoantigen Prioritization

(2017) Markus Müller et al.   Frontiers in Immunology

Thermal ablation and immunomodulation: From preclinical experiments to clinical trials

(2017) H. Takaki et al.   Diagnostic and Interventional Imaging

A minimally invasive optical trapping system to understand cellular interactions at onset of an immune response

(2017) David G. Glass et al.   PLoS One

Tumor-Infiltrating Lymphocytes: A Promising Biomarker in Breast Cancer

(2016) Barbara Ingold Heppner et al.   Breast Care

A Pilot Study of Preoperative Single-Dose Ipilimumab and/or Cryoablation in Women with Early-Stage Breast Cancer with Comprehensive Immune Profiling

(2016) H. L. McArthur et al.   CLINICAL CANCER RESEARCH

Dendritic Cell-Based Immunotherapy: State of the Art and Beyond

(2016) K. F. Bol et al.   CLINICAL CANCER RESEARCH

PD-1 Blockade Boosts Radiofrequency Ablation-Elicited Adaptive Immune Responses against Tumor

(2016) L. Shi et al.   CLINICAL CANCER RESEARCH

Migration of dendritic cells to the lymph nodes and its enhancement to drive anti-tumor responses

(2016) Narges Seyfizadeh et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Phase II randomised trial of autologous tumour lysate dendritic cell plus best supportive care compared with best supportive care in pre-treated advanced colorectal cancer patients

(2016) Miguel Caballero-Baños et al.   EUROPEAN JOURNAL OF CANCER

Large-scale analysis of genome and transcriptome alterations in multiple tumors unveils novel cancer-relevant splicing networks

(2016) Endre Sebestyén et al.   GENOME RESEARCH

Macrophage-based cell therapies: The long and winding road

(2016) Simon Lee et al.   JOURNAL OF CONTROLLED RELEASE

Unsupervised HLA Peptidome Deconvolution Improves Ligand Prediction Accuracy and Predicts Cooperative Effects in Peptide–HLA Interactions

(2016) Michal Bassani-Sternberg et al.   JOURNAL OF IMMUNOLOGY

Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy

(2016) Lena M. Kranz et al.   NATURE

Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes

(2016) Amalie Kai Bentzen et al.   NATURE BIOTECHNOLOGY

Thermal ablation in cancer

(2016) Yong Liu et al.   Oncology Letters

The tumour microenvironment harbours ontogenically distinct dendritic cell populations with opposing effects on tumour immunity

(2016) Damya Laoui et al.   Nature Communications

Global proteogenomic analysis of human MHC class I-associated peptides derived from non-canonical reading frames

(2016) Céline M. Laumont et al.   Nature Communications

Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry

(2016) Michal Bassani-Sternberg et al.   Nature Communications

Activated dendritic cells delivered in tissue compatible biomatrices induce in-situ anti-tumor CTL responses leading to tumor regression

(2016) Vivek Verma et al.   Oncotarget

pVAC-Seq: A genome-guided in silico approach to identifying tumor neoantigens

(2016) Jasreet Hundal et al.   Genome Medicine

Tumor- and Neoantigen-Reactive T-cell Receptors Can Be Identified Based on Their Frequency in Fresh Tumor

(2016) A. Pasetto et al.   Cancer Immunology Research

Human dendritic cell subsets and function in health and disease

(2015) Meredith O’Keeffe et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Dendritic cells pulsed with tumor cells killed by high hydrostatic pressure induce strong immune responses and display therapeutic effects both in murine TC-1 and TRAMP-C2 tumors when combined with docetaxel chemotherapy

(2015) ROMANA MIKYŠKOVÁ et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Tumor-Infiltrating Dendritic Cells in Cancer Pathogenesis

(2015) Jo Marie Tran Janco et al.   JOURNAL OF IMMUNOLOGY

A Phase I Clinical Trial of CD1c (BDCA-1)+ Dendritic Cells Pulsed With HLA-A*0201 Peptides for Immunotherapy of Metastatic Hormone Refractory Prostate Cancer

(2015) Rebecca L. Prue et al.   JOURNAL OF IMMUNOTHERAPY

Synergism between cryoablation and GM-CSF

(2015) Hongchao Xu et al.   NEUROREPORT

Neoantigens in cancer immunotherapy

(2015) T. N. Schumacher et al.   SCIENCE

A dendritic cell vaccine increases the breadth and diversity of melanoma neoantigen-specific T cells

(2015) B. M. Carreno et al.   SCIENCE

Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

(2015) N. A. Rizvi et al.   SCIENCE

Clonal status of actionable driver events and the timing of mutational processes in cancer evolution

(2015) Nicholas McGranahan et al.   Science Translational Medicine

Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia

(2015) David L. Porter et al.   Science Translational Medicine

Vaccines, Adjuvants, and Dendritic Cell Activators—Current Status and Future Challenges

(2015) Joseph Obeid et al.   SEMINARS IN ONCOLOGY

Radiotherapy and Immunogenic Cell Death

(2015) Encouse B. Golden et al.   SEMINARS IN RADIATION ONCOLOGY

Profiling lymphocyte interactions at the single-cell level by microfluidic cell pairing

(2015) Burak Dura et al.   Nature Communications

In vivo immunological antitumor effect of OK-432-stimulated dendritic cell transfer after radiofrequency ablation

(2014) Hidetoshi Nakagawa et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Therapeutic DC vaccination with IL-2 as a consolidation therapy for ovarian cancer patients: a phase I/II trial

(2014) Soyoung Baek et al.   Cellular & Molecular Immunology

A Pilot Trial Using Lymphocytes Genetically Engineered with an NY-ESO-1-Reactive T-cell Receptor: Long-term Follow-up and Correlates with Response

(2014) P. F. Robbins et al.   CLINICAL CANCER RESEARCH

Immune Escape Mechanisms as a Guide for Cancer Immunotherapy

(2014) G. L. Beatty et al.   CLINICAL CANCER RESEARCH

Open-label, multi-center, non-randomized, single-arm study to evaluate the safety and efficacy of dendritic cell immunotherapy in patients with refractory solid malignancies, on supportive care

(2014) Poonamalle Parthasarathy Bapsy et al.   CYTOTHERAPY

The immune escape in melanoma: role of the impaired dendritic cell function

(2014) Marco Tucci et al.   Expert Review of Clinical Immunology

Targeting nanoparticles to CD40, DEC-205 or CD11c molecules on dendritic cells for efficient CD8+ T cell response: A comparative study

(2014) Luis J. Cruz et al.   JOURNAL OF CONTROLLED RELEASE

Genomic and bioinformatic profiling of mutational neoepitopes reveals new rules to predict anticancer immunogenicity

(2014) Fei Duan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Clinical use of dendritic cells for cancer therapy

(2014) Sébastien Anguille et al.   LANCET ONCOLOGY

Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma

(2014) Alexandra Snyder et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mechanism of Action of Immunotherapy

(2014) Mary L. Disis   SEMINARS IN ONCOLOGY

A Systemic Complete Response of Metastatic Melanoma to Local Radiation and Immunotherapy

(2014) Susan M. Hiniker et al.   Translational Oncology

Dendritic cell defects in the colorectal cancer

(2014) Annalisa Legitimo et al.   Human Vaccines & Immunotherapeutics

Toll-Like Receptor Signaling Pathways

(2014) Takumi Kawasaki et al.   Frontiers in Immunology

Multiple chimeric antigen receptors successfully target chondroitin sulfate proteoglycan 4 in several different cancer histologies and cancer stem cells

(2014) Rachel E Beard et al.   Journal for ImmunoTherapy of Cancer

Therapeutic vaccination against autologous cancer stem cells with mRNA-transfected dendritic cells in patients with glioblastoma

(2013) Einar Osland Vik-Mo et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Numerical defect of circulating dendritic cell subsets and defective dendritic cell generation from monocytes of patients with advanced melanoma

(2013) Alessandra Failli et al.   CANCER LETTERS

Targeting of 111In-Labeled Dendritic Cell Human Vaccines Improved by Reducing Number of Cells

(2013) E. H. J. G. Aarntzen et al.   CLINICAL CANCER RESEARCH

Oncology Meets Immunology: The Cancer-Immunity Cycle

(2013) Daniel S. Chen et al.   IMMUNITY

NetMHCstab- predicting stability of peptide-MHC-I complexes; impacts for cytotoxic T lymphocyte epitope discovery

(2013) Kasper W. Jørgensen et al.   IMMUNOLOGY

Defective Generation and Maturation of Dendritic Cells from Monocytes in Colorectal Cancer Patients during the Course of Disease

(2013) Giulia Orsini et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Comparison of Glioma-associated Antigen Peptide-loaded Versus Autologous Tumor Lysate-loaded Dendritic Cell Vaccination in Malignant Glioma Patients

(2013) Robert M. Prins et al.   JOURNAL OF IMMUNOTHERAPY

CTLA-4 Blockade Enhances Antitumor Immunity of Intratumoral Injection of Immature Dendritic Cells into Irradiated Tumor in a Mouse Colon Cancer Model

(2013) Cheol-Hun Son et al.   JOURNAL OF IMMUNOTHERAPY

TLR agonists: our best frenemy in cancer immunotherapy

(2013) Sabina Kaczanowska et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Combinatorial tetramer staining and mass cytometry analysis facilitate T-cell epitope mapping and characterization

(2013) Evan W Newell et al.   NATURE BIOTECHNOLOGY

Combination Treatment With Comprehensive Cryoablation and Immunotherapy in Metastatic Pancreatic Cancer

(2013) Lizhi Niu et al.   PANCREAS

MHC Class I-Associated Phosphopeptides Are the Targets of Memory-like Immunity in Leukemia

(2013) M. Cobbold et al.   Science Translational Medicine

Advances in the study of HLA-restricted epitope vaccines

(2013) Lingxiao Zhao et al.   Human Vaccines & Immunotherapeutics

Properties of MHC Class I Presented Peptides That Enhance Immunogenicity

(2013) Jorg J. A. Calis et al.   PLoS Computational Biology

An Abscopal Response to Radiation and Ipilimumab in a Patient with Metastatic Non-Small Cell Lung Cancer

(2013) E. B. Golden et al.   Cancer Immunology Research

Reducing cell number improves the homing of dendritic cells to lymph nodes upon intradermal vaccination

(2013) Erik HJG Aarntzen et al.   OncoImmunology

Deciphering the Message Broadcast by Tumor-Infiltrating Dendritic Cells

(2012) Nina Karthaus et al.   AMERICAN JOURNAL OF PATHOLOGY

Immunogenic Cell Death in Cancer Therapy

(2012) Guido Kroemer et al.   Annual Review of Immunology

Metastatic melanoma patients treated with dendritic cell vaccination, Interleukin-2 and metronomic cyclophosphamide: results from a phase II trial

(2012) Eva Ellebaek et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Lack of T-cell responses following autologous tumour lysate pulsed dendritic cell vaccination, in patients with relapsed osteosarcoma

(2012) Nourredine Himoudi et al.   Clinical & Translational Oncology

Genetic cancer vaccines: current status and perspectives

(2012) Luigi Aurisicchio et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Radiation Therapy to Convert the Tumor Into an In Situ Vaccine

(2012) Silvia C. Formenti et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

The immunosuppressive factors IL-10, TGF-β, and VEGF do not affect the antigen-presenting function of CD40-activated B cells

(2012) Alexander Shimabukuro-Vornhagen et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The secret ally: immunostimulation by anticancer drugs

(2012) Lorenzo Galluzzi et al.   NATURE REVIEWS DRUG DISCOVERY

Immunologic Correlates of the Abscopal Effect in a Patient with Melanoma

(2012) Michael A. Postow et al.   NEW ENGLAND JOURNAL OF MEDICINE

Trial watch: FDA-approved Toll-like receptor agonists for cancer therapy

(2012) Erika Vacchelli et al.   OncoImmunology

Induction of Specific Cellular and Humoral Responses Against Renal Cell Carcinoma After Combination Therapy With Cryoablation and Granulocyte-Macrophage Colony Stimulating Factor

(2011) Archana Thakur et al.   JOURNAL OF IMMUNOTHERAPY

PD-1 Blockade by CT-011, Anti-PD-1 Antibody, Enhances Ex Vivo T-cell Responses to Autologous Dendritic Cell/Myeloma Fusion Vaccine

(2011) Jacalyn Rosenblatt et al.   JOURNAL OF IMMUNOTHERAPY

Combination therapy of renal cell carcinoma or breast cancer patients with dendritic cell vaccine and IL-2: results from a phase I/II trial

(2011) Soyoung Baek et al.   Journal of Translational Medicine

Force Measurements of TCR/pMHC Recognition at T Cell Surface

(2011) Pierre-Henri Puech et al.   PLoS One

Adjuvant Immunotherapy with Whole-Cell Lysate Dendritic Cells Vaccine for Glioblastoma Multiforme: A Phase II Clinical Trial

(2011) Der-Yang Cho et al.   World Neurosurgery

Vaccination with autologous dendritic cells pulsed with multiple tumor antigens for treatment of patients with malignant melanoma: results from a phase I/II trial

(2010) Redas Trepiakas et al.   CYTOTHERAPY

Resistance of CD45RA- T Cells to Apoptosis and Functional Impairment, and Activation of Tumor-Antigen Specific T Cells during Radiation Therapy of Prostate Cancer

(2010) Z. Tabi et al.   JOURNAL OF IMMUNOLOGY

Integration of autologous dendritic cell-based immunotherapy in the primary treatment for patients with newly diagnosed glioblastoma multiforme: a pilot study

(2010) Hilko Ardon et al.   JOURNAL OF NEURO-ONCOLOGY

Phase I study of autologous dendritic cell tumor vaccine in patients with non-small cell lung cancer

(2010) Soo-Jung Um et al.   LUNG CANCER

Dendritic cell vaccination in human melanoma: relationships between clinical effects and vaccine parameters

(2010) Noriaki Nakai et al.   Pigment Cell & Melanoma Research

Up-regulation of the Pro-inflammatory Chemokine CXCL16 is a Common Response of Tumor Cells to Ionizing Radiation

(2010) Satoko Matsumura et al.   RADIATION RESEARCH

Dendritic Cell Vaccination Combined with CTLA4 Blockade in Patients with Metastatic Melanoma

(2009) A. Ribas et al.   CLINICAL CANCER RESEARCH

Clinical and Immunologic Effects of Intranodal Autologous Tumor Lysate-Dendritic Cell Vaccine with Aldesleukin (Interleukin 2) and IFN- 2a Therapy in Metastatic Renal Cell Carcinoma Patients

(2009) T. Schwaab et al.   CLINICAL CANCER RESEARCH

Phase Ib Trial Assessing Autologous, Tumor-pulsed Dendritic Cells as a Vaccine Administered With or Without IL-2 in Patients With Metastatic Melanoma

(2009) Bruce G. Redman et al.   JOURNAL OF IMMUNOTHERAPY

Cyclophosphamide Unmasks an Antimetastatic Effect of Local Tumor Cryoablation

(2009) M. Y. Levy et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Infection-mimicking materials to program dendritic cells in situ

(2009) Omar A. Ali et al.   NATURE MATERIALS

Autologous Large Multivalent Immunogen Vaccine in Patients With Metastatic Melanoma and Renal Cell Carcinoma

(2008) Arkadiusz Z. Dudek et al.   AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS

Injectable dendritic cell-carrying alginate gels for immunization and immunotherapy

(2008) Yuki Hori et al.   BIOMATERIALS

Vaccination with autologous tumor-loaded dendritic cells induces clinical and immunologic responses in indolent B-cell lymphoma patients with relapsed and measurable disease: a pilot study

(2008) M. Di Nicola et al.   BLOOD

CD40-activated B cells can be generated in high number and purity in cancer patients: analysis of immunogenicity and homing potential

(2008) E. Kondo et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Nanoparticles target distinct dendritic cell populations according to their size

(2008) Vania Manolova et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Reengineering dendritic cell-based anti-cancer vaccines

(2008) Gary K. Koski et al.   IMMUNOLOGICAL REVIEWS

Therapeutic Dendritic Cell Vaccination of Patients With Metastatic Renal Cell Carcinoma

(2008) Annika Berntsen et al.   JOURNAL OF IMMUNOTHERAPY

Clinical Grade OK432-activated Dendritic Cells

(2008) Emma West et al.   JOURNAL OF IMMUNOTHERAPY

Antigens for cancer immunotherapy

(2008) Michelle A. Neller et al.   SEMINARS IN IMMUNOLOGY