Article
Radiology, Nuclear Medicine & Medical Imaging
Thomas Le Corroller, Thomas Vives, Jean-Camille Mattei, Vanessa Pauly, Daphne Guenoun, Alexandre Rochwerger, Pierre Champsaur
Summary: This study retrospectively analyzed 50 patients who underwent CT-guided cryoablation for osteoid osteoma treatment, showing that this approach was safe, effective, and durable, with a high clinical success rate of 96%. The majority of patients could undergo the treatment without general anesthesia, and the pain relief was significant both in the short and long term follow-up.
Article
Radiology, Nuclear Medicine & Medical Imaging
Mansur A. Ghani, Amandip Bangar, Yunpeng Yang, Eunkyeong Jung, Consuelo Sauceda, Tyler Mandt, Sourabh Shukla, Nicholas J. G. Webster, Nicole F. Steinmetz, Isabel G. Newton
Summary: The study aimed to test the effectiveness of cryoablation combined with intratumoral immunomodulating nanoparticles (CPMV) in inducing systemic antitumoral immunity in a murine model of hepatocellular carcinoma (HCC). The results showed that cryoablation combined with intratumoral CPMV was the most effective treatment for the treated tumors and also slowed the growth of untreated tumors.
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Article
Oncology
Hongjin Shi, Jinze Li, Zhinan Fan, Jing Yang, Shi Fu, Haifeng Wang, Jiansong Wang, Jinsong Zhang
Summary: The study compared the effectiveness and security of radiofrequency ablation (RFA) and cryoablation (CA) for T1 renal tumors. The analysis showed that CA may be associated with lower local recurrence rates, but there were no significant differences in terms of primary technique efficacy rate, 5-year survival rate, changes in serum creatinine, and complication rate between the two groups.
FRONTIERS IN ONCOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Elena Serrano, Federico Zarco, Anne E. Gill, C. Matthew Hawkins, Napoleon Macias, Emilio J. Inarejos Clemente, Ferran Torner, Ignasi Barber, Daniel Corominas, Enrique Ladera Gonzalez, Antonio Lopez-Rueda, Fernando M. Gomez
Summary: Percutaneous cryoablation is potentially safe and effective for treating chondroblastoma and osteoblastoma in children and adolescents, with technical and clinical success achieved in all patients, and no evidence of recurrence on imaging follow-up for at least 6 months.
INSIGHTS INTO IMAGING
(2021)
Article
Medicine, General & Internal
Jason G. Andrade, George A. Wells, Marc W. Deyell, Matthew Bennett, Vidal Essebag, Jean Champagne, Jean-Francois Roux, Derek Yung, Allan Skanes, Yaariv Khaykin, Carlos Morillo, Umjeet Jolly, Paul Novak, Evan Lockwood, Guy Amit, Paul Angaran, John Sapp, Stephan Wardell, Sandra Lauck, Laurent Macle, Atul Verma
Summary: In patients with symptomatic, paroxysmal atrial fibrillation, catheter cryoballoon ablation was associated with a significantly lower rate of atrial fibrillation recurrence compared to antiarrhythmic drug therapy. The ablation group also had better outcomes in terms of atrial tachyarrhythmia occurrence and atrial fibrillation burden.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Review
Medicine, Research & Experimental
Kijung Kwak, Bo Yu, Robert J. Lewandowski, Dong-Hyun Kim
Summary: With the advancements in modern imaging, minimally invasive ablative procedures have become popular alternatives to surgical removal of tumors. Cryoablation, a non-heat-based ablation method, is increasingly being used for treating various solid tumors. Nanocarriers have shown potential in cryoablation therapy, offering precise treatment and immune modulation.
Editorial Material
Multidisciplinary Sciences
David H. H. Wang
Summary: The discovery of extrachromosomal DNA in non-cancerous tissue challenges the previous belief that it is exclusive to cancer cells, suggesting its potential early involvement in malignant transformation.
Review
Radiology, Nuclear Medicine & Medical Imaging
Pankaj Gupta, Muniraju Maralakunte, Praveen Kumar-M, Karamvir Chandel, Sreedhara B. Chaluvashetty, Harish Bhujade, Naveen Kalra, Manavjit Singh Sandhu
Summary: The study compared the overall survival and local recurrence following radiofrequency ablation, microwave ablation, and cryoablation for very early and early hepatocellular carcinoma. The results showed that these three methods are equally effective for locoregional treatment of very early and early HCC, and age and tumor size did not influence the treatment effect.
EUROPEAN RADIOLOGY
(2021)
Article
Medicine, General & Internal
Lorenzo Bertolotti, Federica Segato, Francesco Pagnini, Sebastiano Buti, Andrea Casarin, Antonio Celia, Francesco Ziglioli, Umberto Maestroni, Giuseppe Pedrazzi, Velio Ascenti, Chiara Martini, Calogero Cicero, Massimo De Filippo
Summary: The efficacy and complication rates of percutaneous radiofrequency ablation (RFA) and cryoablation (CA) in the treatment of T1 renal masses were retrospectively investigated. The results showed that both RFA and CA were effective in treating renal masses, with rare major complications.
Article
Cardiac & Cardiovascular Systems
Alwin Zweerink, Elise Bakelants, Carine Stettler, Haran Burri
Summary: This study compared the procedural characteristics and outcomes of cryoablation and radiofrequency ablation for AVN ablation in patients with HBP. Cryoablation did not show any advantage over RFA and tended to require more redo procedures. Maintaining a distance of >= 6 mm from the His lead tip is recommended to avoid a rise in capture thresholds.
Article
Multidisciplinary Sciences
Michal Mauda-Havakuk, Natalie M. Hawken, Joshua W. Owen, Andrew S. Mikhail, Ankit Saxena, Baktiar Karim, Paul G. Wakim, William F. Pritchard, John W. Karanian, Bradford J. Wood
Summary: The immune responses to radiofrequency ablation (RFA) and cryoablation (CRA) were characterized and compared in a mouse model of colon cancer. The study found that both RFA and CRA induced cell death, reduced systemic T-regulatory cells and myeloid-derived suppressor cells, and affected cytokine secretion. However, RFA demonstrated more pronounced anti-tumoral immunity in the tumor microenvironment, while CRA induced a wider array of cytokine secretion.
SCIENTIFIC REPORTS
(2022)
Article
Cardiac & Cardiovascular Systems
Jason G. Andrade, Marc W. Deyell, Paul Khairy, Jean Champagne, Peter Leong-Sit, Paul Novak, Lawrence Sterns, Jean-Francois Roux, John Sapp, Richard Bennett, Matthew Bennett, Nathaniel Hawkins, Prashanthan Sanders, Laurent Macle
Summary: Catheter ablation using radiofrequency energy for paroxysmal AF can reduce the risk of progression to persistent AF.
EUROPEAN HEART JOURNAL
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Alan Alper Sag, Jennifer M. Perkins, Hadiza S. Kazaure, Michael T. Stang, Daniel J. Rocke, Alissa Collins, Jennifer H. Choe, Randall P. Scheri
Summary: This study aimed to demonstrate the safety, feasibility, and effectiveness of cryoablation for recurrent papillary thyroid cancer that could not undergo reoperation due to scarring. The results showed that cryoablation achieved good outcomes, with an average tumor volume reduction rate of 88%, 60% of tumors completely involuting or partially involuting, and no local progression or permanent complications.
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Review
Immunology
Li Yin, Xing-yu Li, Lin-lin Zhu, Gui-lai Chen, Zhuo Xiang, Qing-qing Wang, Jing-wang Bi, Qiang Wang
Summary: Image-guided tumor ablation, which eliminates tumor cells through physical or chemical stimulation, is a less invasive and more precise treatment option for local tumor treatment. Clinical studies have shown that tumor ablation not only kills tumor cells directly, but also activates immune responses, leading to short-term anti-tumor response, immunosuppression reduction, immune enhancement, and reduction or disappearance of distant tumor foci. The combination of tumor ablation and immunotherapy could potentially improve therapeutic outcomes.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Urology & Nephrology
Savio D. Pandolfo, Umberto Carbonara, Alp T. Beksac, Ithaar Derweesh, Antonio Celia, Riccardo Schiavina, Jeffrey Elbich, Giuseppe Basile, Lance J. Hampton, Clara Cerrato, Giovanni Costa, Lorenzo Bianchi, Giuseppe Lucarelli, Vincenzo Mirone, Ciro Imbimbo, Fernando J. Kim, Francesco del Giudice, Umberto Capitanio, Jihad Kaouk, Riccardo Autorino
Summary: Based on a retrospective study, microwave ablation (MWA) appears to be a safe and effective treatment option for small renal masses. Compared to cryoablation (CRYO) and radiofrequency ablation (RFA), MWA shows lower complication rates, shorter operation time, and similar surgical and functional outcomes.
MINERVA UROLOGY AND NEPHROLOGY
(2023)