Trial watch: FDA-approved Toll-like receptor agonists for cancer therapy

Immunization of Malignant Melanoma Patients with Full-Length NY-ESO-1 Protein Using TLR7 Agonist Imiquimod as Vaccine Adjuvant

(2014) S. Adams et al.   JOURNAL OF IMMUNOLOGY

A Randomized Trial of the Off-label Use of Imiquimod, 5%, Cream With vs Without Tazarotene, 0.1%, Gel for the Treatment of Lentigo Maligna, Followed by Conservative Staged Excisions

(2012) Mark A. Hyde et al.   ARCHIVES OF DERMATOLOGY

Topical treatment of cutaneous Kaposi sarcoma with imiquimod 5% in renal-transplant recipients: a clinicopathological observation

(2012) B. M. Prinz Vavricka et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Imiquimod clears tumors in mice independent of adaptive immunity by converting pDCs into tumor-killing effector cells

(2012) Barbara Drobits et al.   JOURNAL OF CLINICAL INVESTIGATION

The secret ally: immunostimulation by anticancer drugs

(2012) Lorenzo Galluzzi et al.   NATURE REVIEWS DRUG DISCOVERY

Treatment of Multifocal Bowenʼs Disease in Immunocompromised Women With Surgery and Topical Imiquimod

(2012) Suhasini Kaushal et al.   OBSTETRICS AND GYNECOLOGY

Trial Watch

(2012) Lorenzo Galluzzi et al.   OncoImmunology

Trial Watch: Monoclonal antibodies in cancer therapy

(2012) Lorenzo Galluzzi et al.   OncoImmunology

Trial Watch

(2012) Erika Vacchelli et al.   OncoImmunology

Trial Watch

(2012) Lorenzo Galluzzi et al.   OncoImmunology

Trial watch

(2012) Erika Vacchelli et al.   OncoImmunology

Randomized clinical trial of imiquimod: an adjunct to treating cervical dysplasia

(2011) Deirdre R. Pachman et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Imiquimod as an Adjuvant Treatment Measure for Desmoplastic Trichoepithelioma

(2011) Sang-Hee Seo et al.   Annals of Dermatology

Efficacy of Imiquimod Cream, 5%, for Lentigo Maligna After Complete Excision

(2011) Lena Ly   ARCHIVES OF DERMATOLOGY

Imiquimod 5% cream for the treatment of nasal lesion of metastatic renal cell carcinoma

(2011) MAKIKO ASAKURA et al.   Dermatologic Therapy

Treatment of vulvar intraepithelial neoplasia with topical imiquimod: Seven years median follow-up of a randomized clinical trial

(2011) Annelinde Terlou et al.   GYNECOLOGIC ONCOLOGY

Immunogenicity and safety of the HPV-16/18 AS04-adjuvanted vaccine administered as a 2-dose schedule compared to the licensed 3-dose schedule

(2011) Barbara Romanowski et al.   Human vaccines & immunotherapeutics

Efficacy of a bivalent HPV 16/18 vaccine against anal HPV 16/18 infection among young women: a nested analysis within the Costa Rica Vaccine Trial

(2011) Aimée R Kreimer et al.   LANCET ONCOLOGY

Success of HPV vaccination is now a matter of coverage

(2011) Mark Schiffman et al.   LANCET ONCOLOGY

Overall efficacy of HPV-16/18 AS04-adjuvanted vaccine against grade 3 or greater cervical intraepithelial neoplasia: 4-year end-of-study analysis of the randomised, double-blind PATRICIA trial

(2011) Matti Lehtinen et al.   LANCET ONCOLOGY

Cross-protective efficacy of HPV-16/18 AS04-adjuvanted vaccine against cervical infection and precancer caused by non-vaccine oncogenic HPV types: 4-year end-of-study analysis of the randomised, double-blind PATRICIA trial

(2011) Cosette M Wheeler et al.   LANCET ONCOLOGY

Complete regression of subcutaneous and cutaneous metastatic melanoma with high-dose intralesional interleukin 2 in combination with topical imiquimod and retinoid cream

(2011) Miki Shirakawa Garcia et al.   MELANOMA RESEARCH

A Prospective Self-Controlled Phase II Study of Imiquimod 5% Cream in the Treatment of Infantile Hemangioma

(2011) ChengHong Jiang et al.   PEDIATRIC DERMATOLOGY

Co-administration of human papillomavirus-16/18 AS04-adjuvanted vaccine with hepatitis B vaccine: Randomized study in healthy girls

(2011) Channa E. Schmeink et al.   VACCINE

Edward Jenner and the Small Pox Vaccine

(2011) Kendall A. Smith   Frontiers in Immunology

Phase II trial of imiquimod and HPV therapeutic vaccination in patients with vulval intraepithelial neoplasia

(2010) S Daayana et al.   BRITISH JOURNAL OF CANCER

Monophosphoryl lipid A plus IFNγ maturation of dendritic cells induces antigen-specific CD8+ cytotoxic T cells with high cytolytic potential

(2010) Anja ten Brinke et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

K562/GM-CSF Immunotherapy Reduces Tumor Burden in Chronic Myeloid Leukemia Patients with Residual Disease on Imatinib Mesylate

(2010) B. D. Smith et al.   CLINICAL CANCER RESEARCH

Robert Koch and the ‘golden age’ of bacteriology

(2010) Steve M. Blevins et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Vaccination with a Human Papillomavirus (HPV)-16/18 AS04-Adjuvanted Cervical Cancer Vaccine in Korean Girls Aged 10-14 Years

(2010) Young-Jae Kim et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

Imiquimod 2.5% and 3.75% for the treatment of actinic keratoses: Results of two placebo-controlled studies of daily application to the face and balding scalp for two 2-week cycles

(2010) Neil Swanson et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Imiquimod 2.5% and 3.75% for the treatment of actinic keratoses: Results of two placebo-controlled studies of daily application to the face and balding scalp for two 3-week cycles

(2010) C. William Hanke et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Targeting Toll-like receptors: emerging therapeutics?

(2010) Elizabeth J. Hennessy et al.   NATURE REVIEWS DRUG DISCOVERY

Identification of a Primary Target of Thalidomide Teratogenicity

(2010) T. Ito et al.   SCIENCE

The SINS trial: A randomised controlled trial of excisional surgery versus imiquimod 5% cream for nodular and superficial basal cell carcinoma

(2010) Mara Ozolins et al.   Trials

Results of long-term follow-up of patients with superficial bladder carcinoma treated with intravesically applied bacillus Calmette-Guerin vaccine according to the schedule of 6 weekly + 6 monthly instillations

(2010) Davor Librenjak et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Sustained efficacy and immunogenicity of the HPV-16/18 AS04-adjuvanted vaccine up to 7.3 years in young adult women

(2010) N. De Carvalho et al.   VACCINE

Clinical update of the AS04-Adjuvanted human Papillomavirus-16/18 cervical cancer vaccine, cervarix®

(2009) Tino F. Schwarz   ADVANCES IN THERAPY

Immunotherapy of ovarian cancer with cell wall skeleton ofMycobacterium bovisBacillus Calmette-Guérin: Effect of lymphadenectomy

(2009) Akira Hayashi et al.   CANCER SCIENCE

Complete Resolution of Paget Disease of the Vulva With Imiquimod Cream

(2009) Kenneth D. Hatch et al.   Journal of Lower Genital Tract Disease

Successful treatment of three cases of primary extramammary Paget’s disease of the vulva with Imiquimod - proposal of a therapeutic schedule

(2009) E Sendagorta et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Sustained efficacy and immunogenicity of the human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine: analysis of a randomised placebo-controlled trial up to 6·4 years

(2009)   LANCET

Efficacy of human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine against cervical infection and precancer caused by oncogenic HPV types (PATRICIA): final analysis of a double-blind, randomised study in young women

(2009) J Paavonen et al.   LANCET

Novel multi-peptide vaccination in Hla-A2+ hormone sensitive patients with biochemical relapse of prostate cancer

(2009) Susan Feyerabend et al.   PROSTATE

Topical imiquimod and intralesional interleukin-2 increase activated lymphocytes and restore the Th1/Th2 balance in patients with metastatic melanoma

(2008) D.S. Green et al.   BRITISH JOURNAL OF DERMATOLOGY

Involution of infantile haemangiomas after imiquimod 5% cream

(2008) R. B. M. Barry et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Cryosurgery during topical imiquimod: a successful combination modality for lentigo maligna

(2008) I. D. Bassukas et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Successful treatment of intranasal papillomata with imiquimod cream in a human immunodeficiency virus positive patient

(2008) A Fernández-Casado et al.   JOURNAL OF LARYNGOLOGY AND OTOLOGY

Imiquimod 5% cream for treatment of HIV-negative Kaposi's sarcoma skin lesions: A phase I to II, open-label trial in 17 patients

(2008) Noël Emile Célestin Schartz et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Treatment of Vulvar Intraepithelial Neoplasia with Topical Imiquimod

(2008) Manon van Seters et al.   NEW ENGLAND JOURNAL OF MEDICINE

Booster vaccination of cancer patients with MAGE-A3 protein reveals long-term immunological memory or tolerance depending on priming

(2008) D. Atanackovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of Kaposi's sarcoma under sirolimus-based immunosuppression and successful treatment with imiquimod

(2007) N. Babel et al.   Transplant Infectious Disease