The Role of Alpha-Synuclein and Other Parkinson’s Genes in Neurodevelopmental and Neurodegenerative Disorders

Synucleinopathies: Where we are and where we need to go

(2020) Inês Caldeira Brás et al.   JOURNAL OF NEUROCHEMISTRY

Does Developmental Variability in the Number of Midbrain Dopamine Neurons Affect Individual Risk for Sporadic Parkinson’s Disease?

(2020) Christian U. von Linstow et al.   Journal of Parkinsons Disease

Alpha-Synuclein Physiology and Pathology: A Perspective on Cellular Structures and Organelles

(2020) Luis D. Bernal-Conde et al.   Frontiers in Neuroscience

Alpha-synuclein/synapsin III pathological interplay boosts the motor response to methylphenidate

(2020) Gaia Faustini et al.   NEUROBIOLOGY OF DISEASE

MLPA is a practical and complementary alternative to CMA for diagnostic testing in patients with autism spectrum disorders and identifying new candidate CNVs associated with autism

(2019) Pavlina Capkova et al.   PeerJ

Dementia in Down syndrome: unique insights for Alzheimer disease research

(2019) Ira T. Lott et al.   Nature Reviews Neurology

Systems Analysis of the 22q11.2 Microdeletion Syndrome Converges on a Mitochondrial Interactome Necessary for Synapse Function and Behavior

(2019) Avanti Gokhale et al.   JOURNAL OF NEUROSCIENCE

The A30P α-synuclein mutation decreases subventricular zone proliferation

(2019) Xue-Ming Zhang et al.   HUMAN MOLECULAR GENETICS

Synaptotagmin-11 mediates a vesicle trafficking pathway that is essential for development and synaptic plasticity

(2019) Masafumi Shimojo et al.   GENES & DEVELOPMENT

Selective vulnerability in α-synucleinopathies

(2019) Javier Alegre-Abarrategui et al.   ACTA NEUROPATHOLOGICA

Mood symptoms and suicidality across the autism spectrum

(2019) L. Dell'Osso et al.   COMPREHENSIVE PSYCHIATRY

Synapsins regulate α-synuclein functions

(2019) Merav Atias et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional cooperation of α-synuclein and VAMP2 in synaptic vesicle recycling

(2019) Jichao Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impulse Control Disorders in Parkinson's Disease. A Brief and Comprehensive Review

(2019) Emilia M. Gatto et al.   Frontiers in Neurology

The physiological role of α‐synuclein and its relationship to Parkinson’s Disease

(2019) David Sulzer et al.   JOURNAL OF NEUROCHEMISTRY

Adult neurogenesis in the mammalian dentate gyrus

(2019) Louise C. Abbott et al.   ANATOMIA HISTOLOGIA EMBRYOLOGIA

Parkinson Disease Epidemiology, Pathology, Genetics, and Pathophysiology

(2019) David K. Simon et al.   CLINICS IN GERIATRIC MEDICINE

Adapting ACMG/AMP sequence variant classification guidelines for single-gene copy number variants

(2019) Tracy Brandt et al.   GENETICS IN MEDICINE

The 22q11 low copy repeats are characterized by unprecedented size and structural variability

(2019) Wolfram Demaerel et al.   GENOME RESEARCH

Progress in the genetic analysis of Parkinson’s disease

(2019) Andrew Singleton et al.   HUMAN MOLECULAR GENETICS

Genetic Causes and Modifiers of Autism Spectrum Disorder

(2019) Lauren Rylaarsdam et al.   Frontiers in Cellular Neuroscience

Parkinson disease

(2019) R. Balestrino et al.   EUROPEAN JOURNAL OF NEUROLOGY

Prevalence of Depression and Anxiety in Parkinson Disease and Impact on Quality of Life: A Community-Based Study in Spain

(2019) Fany Chuquilín-Arista et al.   JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY

Neuropathology of RAN translation proteins in fragile X-associated tremor/ataxia syndrome

(2019) Amy Krans et al.   Acta Neuropathologica Communications

Fragile X-associated tremor ataxia syndrome with co-occurrent progressive supranuclear palsy-like neuropathology

(2019) Amanda N. Sacino et al.   Acta Neuropathologica Communications

Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

(2019) Mike A Nalls et al.   LANCET NEUROLOGY

Somatic copy number gains of α-synuclein (SNCA) in Parkinson’s disease and multiple system atrophy brains

(2018) Katya Mokretar et al.   BRAIN

Synaptic markers of cognitive decline in neurodegenerative diseases: a proteomic approach

(2018) Erika Bereczki et al.   BRAIN

Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults

(2018) Shawn F. Sorrells et al.   NATURE

Typical features of Parkinson disease and diagnostic challenges with microdeletion 22q11.2

(2018) Erik Boot et al.   NEUROLOGY

Synaptotagmin-11 is a critical mediator of parkin-linked neurotoxicity and Parkinson’s disease-like pathology

(2018) Changhe Wang et al.   Nature Communications

Significant Changes in Plasma Alpha-Synuclein and Beta-Synuclein Levels in Male Children with Autism Spectrum Disorder

(2018) Wilaiwan Sriwimol et al.   Biomed Research International

Advancing Stem Cell Models of Alpha-Synuclein Gene Regulation in Neurodegenerative Disease

(2018) Desiree A. Piper et al.   Frontiers in Neuroscience

Mechanisms of α-Synuclein Induced Synaptopathy in Parkinson's Disease

(2018) Jessika C. Bridi et al.   Frontiers in Neuroscience

Alpha-Synuclein: From Early Synaptic Dysfunction to Neurodegeneration

(2018) Veronica Ghiglieri et al.   Frontiers in Neurology

Synapsin III deficiency hampers α-synuclein aggregation, striatal synaptic damage and nigral cell loss in an AAV-based mouse model of Parkinson’s disease

(2018) Gaia Faustini et al.   ACTA NEUROPATHOLOGICA

Nuclear localization and phosphorylation modulate pathological effects of Alpha-Synuclein

(2018) Raquel Pinho et al.   HUMAN MOLECULAR GENETICS

Does 22q11.2 deletion syndrome contribute to the genetic aetiology of Parkinson’s disease?

(2018) W. Fung et al.   JOURNAL OF NEUROLOGY

Synaptic dysfunction in neurodegenerative and neurodevelopmental diseases: an overview of induced pluripotent stem-cell-based disease models

(2018) Era Taoufik et al.   Open Biology

Autism Spectrum Disorder: Why Do We Know So Little?

(2018) Leonardo Emberti Gialloreti et al.   Frontiers in Neurology

Pathological Study of a FMR1 Premutation Carrier With Progressive Supranuclear Palsy

(2018) Martin Paucar et al.   Frontiers in Genetics

A mouse model of 22q11.2 deletions: Molecular and behavioral signatures of Parkinson’s disease and schizophrenia

(2018) Akiko Sumitomo et al.   Science Advances

Membrane binding, internalization, and sorting of alpha-synuclein in the cell

(2018) Caterina Masaracchia et al.   Acta Neuropathologica Communications

Behavioural and trait changes in parkinsonian patients with impulse control disorder after switching from dopamine agonist to levodopa therapy: results of REIN-PD trial

(2018) Jee-Young Lee et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Synaptopathology Involved in Autism Spectrum Disorder

(2018) Shiqi Guang et al.   Frontiers in Cellular Neuroscience

New Perspectives on Roles of Alpha-Synuclein in Parkinson’s Disease

(2018) Guoxin Zhang et al.   Frontiers in Aging Neuroscience

A Meta-Analysis of α-Synuclein Multiplication in Familial Parkinsonism

(2018) Adam Book et al.   Frontiers in Neurology

ICARUS study: prevalence and clinical features of impulse control disorders in Parkinson’s disease

(2017) Angelo Antonini et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Synaptic regulator α-synuclein in dopaminergic fibers is essentially required for the maintenance of subependymal neural stem cells

(2017) Ana Perez-Villalba et al.   JOURNAL OF NEUROSCIENCE

Sympathetic skin response and heart rate variability in predicting autonomic disorders in patients with Parkinson disease

(2017) Jiang-Qiong Ke et al.   MEDICINE

Quantitative proteomic analysis of Parkin substrates in Drosophila neurons

(2017) Aitor Martinez et al.   Molecular Neurodegeneration

α-Synuclein promotes dilation of the exocytotic fusion pore

(2017) Todd Logan et al.   NATURE NEUROSCIENCE

Epidemiology, environmental risk factors and genetics of Parkinson's disease

(2017) Anna Delamarre et al.   PRESSE MEDICALE

Defective synaptic connectivity and axonal neuropathology in a human iPSC-based model of familial Parkinson’s disease

(2017) Georgia Kouroupi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

β2-Adrenoreceptor is a regulator of the α-synuclein gene driving risk of Parkinson’s disease

(2017) Shuchi Mittal et al.   SCIENCE

Histology Atlas of the Developing Prenatal and Postnatal Mouse Central Nervous System, with Emphasis on Prenatal Days E7.5 to E18.5

(2017) Vivian S. Chen et al.   TOXICOLOGIC PATHOLOGY

Folding Underlies Bidirectional Role of GPR37/Pael-R in Parkinson Disease

(2017) Lina Leinartaité et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Fundamental Elements in Autism: From Neurogenesis and Neurite Growth to Synaptic Plasticity

(2017) James Gilbert et al.   Frontiers in Cellular Neuroscience

Anxiety Disorders and Obsessive-Compulsive Disorder in Individuals with Autism Spectrum Disorder

(2017) Valentina Postorino et al.   Current Psychiatry Reports

An Overview of Autism Spectrum Disorder, Heterogeneity and Treatment Options

(2017) Anne Masi et al.   Neuroscience Bulletin

Synucleins Have Multiple Effects on Presynaptic Architecture

(2017) Karina J. Vargas et al.   Cell Reports

Critical region within 22q11.2 linked to higher rate of autism spectrum disorder

(2017) Caitlin C. Clements et al.   Molecular Autism

The Structure of the Synaptic Vesicle-Plasma Membrane Interface Constrains SNARE Models of Rapid, Synchronous Exocytosis at Nerve Terminals

(2017) Cameron B. Gundersen   Frontiers in Molecular Neuroscience

Parkin Regulates the Activity of Pyruvate Kinase M2

(2016) Kun Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synaptopathies: synaptic dysfunction in neurological disorders - A review from students to students

(2016) Katarzyna Lepeta et al.   JOURNAL OF NEUROCHEMISTRY

Early synaptic dysfunction in Parkinson's disease: Insights from animal models

(2016) Tommaso Schirinzi et al.   MOVEMENT DISORDERS

Combinational losses of synucleins reveal their differential requirements for compensating age-dependent alterations in motor behavior and dopamine metabolism

(2016) Natalie Connor-Robson et al.   NEUROBIOLOGY OF AGING

Severely impaired hippocampal neurogenesis associates with an early serotonergic deficit in a BAC α-synuclein transgenic rat model of Parkinson's disease

(2016) Zacharias Kohl et al.   NEUROBIOLOGY OF DISEASE

Review: Parkinson's disease: from synaptic loss to connectome dysfunction

(2016) Arianna Bellucci et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Neocortical neurogenesis and the etiology of autism spectrum disorder

(2016) Alan Packer   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Environmental risk factors and Parkinson's disease: An umbrella review of meta-analyses

(2016) Vanesa Bellou et al.   PARKINSONISM & RELATED DISORDERS

The Adult Ventricular–Subventricular Zone (V-SVZ) and Olfactory Bulb (OB) Neurogenesis

(2016) Daniel A. Lim et al.   Cold Spring Harbor Perspectives in Biology

Postnatal dysregulation of Notch signal disrupts dendrite development of adult-born neurons in the hippocampus and contributes to memory impairment

(2016) Xue-Feng Ding et al.   Scientific Reports

Parkin Regulation and Neurodegenerative Disorders

(2016) Cheng-Wu Zhang et al.   Frontiers in Aging Neuroscience

Genome-wide analysis of copy number variations identifies PARK2 as a candidate gene for autism spectrum disorder

(2016) Chia-Lin Yin et al.   Molecular Autism

Distinct Effects of Chronic Dopaminergic Stimulation on Hippocampal Neurogenesis and Striatal Doublecortin Expression in Adult Mice

(2016) Rachele Salvi et al.   Frontiers in Neuroscience

α-Synuclein is a Novel Microtubule Dynamase

(2016) Daniele Cartelli et al.   Scientific Reports

Movement disorders and other motor abnormalities in adults with 22q11.2 deletion syndrome

(2015) Erik Boot et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

α-Synuclein and Lewy pathology in Parkinsonʼs disease

(2015) Lorraine V. Kalia et al.   CURRENT OPINION IN NEUROLOGY

It Takes a Village: Constructing the Neurogenic Niche

(2015) Christopher S. Bjornsson et al.   DEVELOPMENTAL CELL

The three ‘P’s of mitophagy: PARKIN, PINK1, and post-translational modifications

(2015) Thomas M. Durcan et al.   GENES & DEVELOPMENT

 -synuclein and synapsin III cooperatively regulate synaptic function in dopamine neurons

(2015) M. Zaltieri et al.   JOURNAL OF CELL SCIENCE

Structure, function and toxicity of alpha-synuclein: the Bermuda triangle in synucleinopathies

(2015) Anna Villar-Piqué et al.   JOURNAL OF NEUROCHEMISTRY

High rates of parkinsonism in adults with autism

(2015) Sergio Starkstein et al.   Journal of Neurodevelopmental Disorders

Comparative mapping of the 22q11.2 deletion region and the potential of simple model organisms

(2015) Alina Guna et al.   Journal of Neurodevelopmental Disorders

Parkinson disease male-to-female ratios increase with age: French nationwide study and meta-analysis

(2015) Frédéric Moisan et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Parkinson's disease

(2015) Lorraine V Kalia et al.   LANCET

Multisystem Lewy body disease and the other parkinsonian disorders

(2015) J William Langston et al.   NATURE GENETICS

Physical biology of human brain development

(2015) Silvia Budday et al.   Frontiers in Cellular Neuroscience

Elevated α-synuclein caused by SNCA gene triplication impairs neuronal differentiation and maturation in Parkinson's patient-derived induced pluripotent stem cells

(2015) L M A Oliveira et al.   Cell Death & Disease

The Synaptic Function of α-Synuclein

(2015) Jacqueline Burré   Journal of Parkinsons Disease

Detecting non-allelic homologous recombination from high-throughput sequencing data

(2015) Matthew M Parks et al.   GENOME BIOLOGY

Evaluation of the Synuclein-γ (SNCG) Gene as a PPARγ Target in Murine Adipocytes, Dorsal Root Ganglia Somatosensory Neurons, and Human Adipose Tissue

(2015) Tamara N. Dunn et al.   PLoS One

Convergence of Genes and Cellular Pathways Dysregulated in Autism Spectrum Disorders

(2014) Dalila Pinto et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Psychiatric Disorders From Childhood to Adulthood in 22q11.2 Deletion Syndrome: Results From the International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome

(2014) Maude Schneider et al.   AMERICAN JOURNAL OF PSYCHIATRY

Longitudinal Volumetric Brain Changes in Autism Spectrum Disorder Ages 6-35 Years

(2014) Nicholas Lange et al.   Autism Research

Terminal chromosome 4q deletion syndrome in an infant with hearing impairment and moderate syndromic features: review of literature

(2014) Barbara Vona et al.   BMC Medical Genetics

Neurogenesis in the Striatum of the Adult Human Brain

(2014) Aurélie Ernst et al.   CELL

Concomitant fragile X-associated tremor ataxia syndrome and Parkinson's disease: a clinicopathological report of two cases: Table 1

(2014) Eduardo De Pablo-Fernandez et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Refining analyses of copy number variation identifies specific genes associated with developmental delay

(2014) Bradley P Coe et al.   NATURE GENETICS

Parkinsonism in fragile X-associated tremor/ataxia syndrome (FXTAS): Revisited

(2014) Yu-Qiong Niu et al.   PARKINSONISM & RELATED DISORDERS

Systems-Based Analyses of Brain Regions Functionally Impacted in Parkinson's Disease Reveals Underlying Causal Mechanisms

(2014) Brigit E. Riley et al.   PLoS One

Higher Vulnerability and Stress Sensitivity of Neuronal Precursor Cells Carrying an Alpha-Synuclein Gene Triplication

(2014) Adrian Flierl et al.   PLoS One

Partial duplication of thePARK2 gene in a child with developmental delay and her normal mother: A second report

(2013) Milena Mariani et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

The Genetic Landscapes of Autism Spectrum Disorders

(2013) Guillaume Huguet et al.   Annual Review of Genomics and Human Genetics

Environmental Toxins and Parkinson's Disease

(2013) Samuel M. Goldman   Annual Review of Pharmacology and Toxicology

Neurotransmitter-mediated control of neurogenesis in the adult vertebrate brain

(2013) D. A. Berg et al.   DEVELOPMENT

Endogenous alpha-synuclein influences the number of dopaminergic neurons in mouse substantia nigra

(2013) Pablo Garcia-Reitboeck et al.   EXPERIMENTAL NEUROLOGY

Chromosomal microarray analysis of consecutive individuals with autism spectrum disorders or learning disability presenting for genetic services

(2013) Jennifer L. Roberts et al.   GENE

Clinical Significance of De Novo and Inherited Copy-Number Variation

(2013) Anneke T. Vulto-van Silfhout et al.   HUMAN MUTATION

Relationship Between Neuropsychiatric Symptoms and Cognitive Performance in De Novo Parkinson’s Disease

(2013) Michele Poletti et al.   JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES

Autism

(2013) Meng-Chuan Lai et al.   LANCET

Advances in the genetics of Parkinson disease

(2013) Joanne Trinh et al.   Nature Reviews Neurology

The Function of α-Synuclein

(2013) Jacob T. Bendor et al.   NEURON

Obsessive Compulsive Personality Disorder and Parkinson’s Disease

(2013) Alessandra Nicoletti et al.   PLoS One

Brain development in rodents and humans: Identifying benchmarks of maturation and vulnerability to injury across species

(2013) Bridgette D. Semple et al.   PROGRESS IN NEUROBIOLOGY

Identification and Rescue of  -Synuclein Toxicity in Parkinson Patient-Derived Neurons

(2013) C. Y. Chung et al.   SCIENCE

 -Synuclein in Parkinson's Disease

(2013) L. Stefanis   Cold Spring Harbor Perspectives in Medicine

Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2

(2013) Jiajie Diao et al.   eLife

Environmental Factors in Autism

(2013) Andreas M. Grabrucker   Frontiers in Psychiatry

Nigrostriatal overabundance of α-synuclein leads to decreased vesicle density and deficits in dopamine release that correlate with reduced motor activity

(2012) Meret Nora Gaugler et al.   ACTA NEUROPATHOLOGICA

α-Synuclein knockout mice have cognitive impairments

(2012) V.S. Kokhan et al.   BEHAVIOURAL BRAIN RESEARCH

Neuropathological, clinical and molecular pathology in female fragile X premutation carriers with and without FXTAS

(2012) F. Tassone et al.   GENES BRAIN AND BEHAVIOR

α-Synuclein Induces Alterations in Adult Neurogenesis in Parkinson Disease Models via p53-mediated Repression of Notch1

(2012) Paula Desplats et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of  -Synuclein in Adult Neurogenesis and Neuronal Maturation in the Dentate Gyrus

(2012) B. Winner et al.   JOURNAL OF NEUROSCIENCE

 -Synuclein Inhibits Intersynaptic Vesicle Mobility and Maintains Recycling-Pool Homeostasis

(2012) D. Scott et al.   JOURNAL OF NEUROSCIENCE

Genome-wide analysis of rare copy number variations reveals PARK2 as a candidate gene for attention-deficit/hyperactivity disorder

(2012) I Jarick et al.   MOLECULAR PSYCHIATRY

The many faces of α-synuclein: from structure and toxicity to therapeutic target

(2012) Hilal A. Lashuel et al.   NATURE REVIEWS NEUROSCIENCE

Impaired olfactory bulb neurogenesis depends on the presence of human wild-type alpha-synuclein

(2012) V.E.L. May et al.   NEUROSCIENCE

Mutation in Parkinson Disease-Associated, G-Protein-Coupled Receptor 37 (GPR37/PaelR) Is Related to Autism Spectrum Disorder

(2012) Eriko Fujita-Jimbo et al.   PLoS One

Impaired neurotransmission caused by overexpression of  -synuclein in nigral dopamine neurons

(2012) M. Lundblad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synaptic Dysfunction in Neurodevelopmental Disorders Associated with Autism and Intellectual Disabilities

(2012) H. Y. Zoghbi et al.   Cold Spring Harbor Perspectives in Biology

Frequency of Nonallelic Homologous Recombination Is Correlated with Length of Homology: Evidence that Ectopic Synapsis Precedes Ectopic Crossing-Over

(2011) Pengfei Liu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

PARK2 copy number aberrations in two children presenting with autism spectrum disorder: Further support of an association and possible evidence for a new microdeletion/microduplication syndrome

(2011) Angela Scheuerle et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

The von Economo neurons in the frontoinsular and anterior cingulate cortex

(2011) John M. Allman et al.   Annals of the New York Academy of Sciences

Genetic Heritability and Shared Environmental Factors Among Twin Pairs With Autism

(2011) Joachim Hallmayer   ARCHIVES OF GENERAL PSYCHIATRY

Decreased reuptake of dopamine in the dorsal striatum in the absence of alpha-synuclein

(2011) Heramb Chadchankar et al.   BRAIN RESEARCH

Functional Alterations to the Nigrostriatal System in Mice Lacking All Three Members of the Synuclein Family

(2011) S. Anwar et al.   JOURNAL OF NEUROSCIENCE

Explaining the Structural Plasticity of α-Synuclein

(2011) Orly Ullman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

FMR1 gray-zone alleles: Association with Parkinson's disease in women?

(2011) Deborah A. Hall et al.   MOVEMENT DISORDERS

Resistance to MPTP-Neurotoxicity in α-Synuclein Knockout Mice Is Complemented by Human α-Synuclein and Associated with Increased β-Synuclein and Akt Activation

(2011) Bobby Thomas et al.   PLoS One

SNCA Triplication Parkinson's Patient's iPSC-derived DA Neurons Accumulate α-Synuclein and Are Susceptible to Oxidative Stress

(2011) Blake Byers et al.   PLoS One

α-Synuclein: Membrane Interactions and Toxicity in Parkinson's Disease

(2010) Pavan K. Auluck et al.   Annual Review of Cell and Developmental Biology

Three phases of DiGeorge/22q11 deletion syndrome pathogenesis during brain development: Patterning, proliferation, and mitochondrial functions of 22q11 genes

(2010) D.W. Meechan et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

A Pathologic Cascade Leading to Synaptic Dysfunction in  -Synuclein-Induced Neurodegeneration

(2010) D. A. Scott et al.   JOURNAL OF NEUROSCIENCE

Advances in environmental epidemiology

(2010) Caroline M. Tanner   MOVEMENT DISORDERS

Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after Endocytosis

(2010) Venu M. Nemani et al.   NEURON

   -Synuclein triple knockout mice reveal age-dependent neuronal dysfunction

(2010) B. Greten-Harrison et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

 -Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro

(2010) J. Burre et al.   SCIENCE

α-Synuclein and dopamine at the crossroads of Parkinson's disease

(2010) Lara Lourenço Venda et al.   TRENDS IN NEUROSCIENCES

Fragile X and autism: Intertwined at the molecular level leading to targeted treatments

(2010) Randi Hagerman et al.   Molecular Autism

Diminished tyrosine hydroxylase immunoreactivity in the cardiac conduction system and myocardium in Parkinson’s disease: an anatomical study

(2009) Estifanos Ghebremedhin et al.   ACTA NEUROPATHOLOGICA

Expression and Subcellular Location of Alpha-Synuclein During Mouse-Embryonic Development

(2009) Shan-chuan Zhong et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Dopamine receptor activation promotes adult neurogenesis in an acute Parkinson model

(2009) Beate Winner et al.   EXPERIMENTAL NEUROLOGY

Forebrain overexpression of α-synuclein leads to early postnatal hippocampal neuron loss and synaptic disruption

(2009) Youngshin Lim et al.   EXPERIMENTAL NEUROLOGY

Single Nigrostriatal Dopaminergic Neurons Form Widely Spread and Highly Dense Axonal Arborizations in the Neostriatum

(2009) W. Matsuda et al.   JOURNAL OF NEUROSCIENCE

α-Synuclein and Its A30P Mutant Affect Actin Cytoskeletal Structure and Dynamics

(2009) Vítor L. Sousa et al.   MOLECULAR BIOLOGY OF THE CELL

Molecular interaction of α-synuclein with tubulin influences on the polymerization of microtubule in vitro and structure of microtubule in cells

(2009) R. M. Zhou et al.   MOLECULAR BIOLOGY REPORTS

Hereditary parkinsonism: Parkinson disease look-alikes-An algorithm for clinicians to “PARK” genes and beyond

(2009) Christine Klein et al.   MOVEMENT DISORDERS

Autism genome-wide copy number variation reveals ubiquitin and neuronal genes

(2009) Joseph T. Glessner et al.   NATURE

Somatic mutations of the Parkinson's disease–associated gene PARK2 in glioblastoma and other human malignancies

(2009) Selvaraju Veeriah et al.   NATURE GENETICS

Probing Compulsive and Impulsive Behaviors, from Animal Models to Endophenotypes: A Narrative Review

(2009) Naomi A Fineberg et al.   NEUROPSYCHOPHARMACOLOGY

Diminished dosage of 22q11 genes disrupts neurogenesis and cortical development in a mouse model of 22q11 deletion/DiGeorge syndrome

(2009) D. W. Meechan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neurological considerations: Autism and Parkinson's disease

(2009) Eric Hollander et al.   PSYCHIATRY RESEARCH

Structural Variation of Chromosomes in Autism Spectrum Disorder

(2008) Christian R. Marshall et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genomic investigation of α-synuclein multiplication and parkinsonism

(2008) Owen A. Ross et al.   ANNALS OF NEUROLOGY

Increased striatal dopamine release and hyperdopaminergic-like behaviour in mice lacking both alpha-synuclein and gamma-synuclein

(2008) Steven L. Senior et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

α-Synuclein–induced Aggregation of Cytoplasmic Vesicles in Saccharomyces cerevisiae

(2008) James H. Soper et al.   MOLECULAR BIOLOGY OF THE CELL

Absence of α-synuclein affects dopamine metabolism and synaptic markers in the striatum of aging mice

(2008) Abdelmojib Al-Wandi et al.   NEUROBIOLOGY OF AGING

Red Blood Cells Are the Major Source of Alpha-Synuclein in Blood

(2008) Robin Barbour et al.   Neurodegenerative Diseases

Parkinsonism in FMR1 premutation carriers may be indistinguishable from Parkinson disease

(2008) Deborah A. Hall et al.   PARKINSONISM & RELATED DISORDERS

Neuroanatomy of autism

(2008) David G. Amaral et al.   TRENDS IN NEUROSCIENCES

Midbrain dopaminergic neuron fate specification: Of mice and embryonic stem cells

(2008) Emily Gale et al.   Molecular Brain

Mutant α-synuclein exacerbates age-related decrease of neurogenesis

(2007) Beate Winner et al.   NEUROBIOLOGY OF AGING

Transcriptional dysregulation in a transgenic model of Parkinson disease

(2007) Talene A. Yacoubian et al.   NEUROBIOLOGY OF DISEASE