Vascular Homeostasis and Inflammation in Health and Disease—Lessons from Single Cell Technologies
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Title
Vascular Homeostasis and Inflammation in Health and Disease—Lessons from Single Cell Technologies
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 21, Issue 13, Pages 4688
Publisher
MDPI AG
Online
2020-07-01
DOI
10.3390/ijms21134688
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Note: Only part of the references are listed.- Single-Cell Transcriptome Atlas of Murine Endothelial Cells
- (2020) Joanna Kalucka et al. CELL
- ATAC-Me Captures Prolonged DNA Methylation of Dynamic Chromatin Accessibility Loci during Cell Fate Transitions
- (2020) Kelly R. Barnett et al. MOLECULAR CELL
- Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function
- (2020) Li Wang et al. NATURE CELL BIOLOGY
- CellPhoneDB: inferring cell–cell communication from combined expression of multi-subunit ligand–receptor complexes
- (2020) Mirjana Efremova et al. Nature Protocols
- Dynamic Interstitial Cell Response during Myocardial Infarction Predicts Resilience to Rupture in Genetically Diverse Mice
- (2020) Elvira Forte et al. Cell Reports
- Transcriptional and Cellular Diversity of the Human Heart
- (2020) Nathan R. Tucker et al. CIRCULATION
- Atherogenic Lipoprotein(a) Increases Vascular Glycolysis, Thereby Facilitating Inflammation and Leukocyte Extravasation
- (2020) Johan G. Schnitzler et al. CIRCULATION RESEARCH
- APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline
- (2020) Axel Montagne et al. NATURE
- Dissecting cellular crosstalk by sequencing physically interacting cells
- (2020) Amir Giladi et al. NATURE BIOTECHNOLOGY
- Machine learning analysis of whole mouse brain vasculature
- (2020) Mihail Ivilinov Todorov et al. NATURE METHODS
- SingleCellSignalR: inference of intercellular networks from single-cell transcriptomics
- (2020) Simon Cabello-Aguilar et al. NUCLEIC ACIDS RESEARCH
- Remodeling of active endothelial enhancers is associated with aberrant gene-regulatory networks in pulmonary arterial hypertension
- (2020) Armando Reyes-Palomares et al. Nature Communications
- Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature
- (2020) Bilal N. Sheikh et al. NATURE CELL BIOLOGY
- Reconstruction of the human blood–brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes
- (2020) Joel W. Blanchard et al. NATURE MEDICINE
- Blood–brain barrier breakdown is an early biomarker of human cognitive dysfunction
- (2019) Daniel A. Nation et al. NATURE MEDICINE
- Endothelium structure and function in kidney health and disease
- (2019) Noemie Jourde-Chiche et al. Nature Reviews Nephrology
- Apolipoprotein E4 Alters Astrocyte Fatty Acid Metabolism and Lipid Droplet Formation
- (2019) Brandon Farmer et al. Cells
- Single-Cell Transcriptome Analysis Maps the Developmental Track of the Human Heart
- (2019) Yueli Cui et al. Cell Reports
- An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics
- (2019) Ilias Angelidis et al. Nature Communications
- Identification of atheroprone shear stress responsive regulatory elements in endothelial cells
- (2019) Olga Bondareva et al. CARDIOVASCULAR RESEARCH
- Single-cell transcriptomic analysis of Alzheimer’s disease
- (2019) Hansruedi Mathys et al. NATURE
- Single-cell expression profiling reveals dynamic flux of cardiac stromal, vascular and immune cells in health and injury
- (2019) Nona Farbehi et al. eLife
- Adventitial Cell Atlas of wt (Wild Type) and ApoE (Apolipoprotein E)-Deficient Mice Defined by Single-Cell RNA Sequencing
- (2019) Wenduo Gu et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Single-Cell Analysis of the Normal Mouse Aorta Reveals Functionally Distinct Endothelial Cell Populations
- (2019) Aditya S. Kalluri et al. CIRCULATION
- Single-cell transcriptome analyses reveal novel targets modulating cardiac neovascularization by resident endothelial cells following myocardial infarction
- (2019) Ziwen Li et al. EUROPEAN HEART JOURNAL
- A human liver cell atlas reveals heterogeneity and epithelial progenitors
- (2019) Nadim Aizarani et al. NATURE
- High-throughput single-cell ChIP-seq identifies heterogeneity of chromatin states in breast cancer
- (2019) Kevin Grosselin et al. NATURE GENETICS
- Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis
- (2019) Robert C. Wirka et al. NATURE MEDICINE
- Amyloid β oligomers constrict human capillaries in Alzheimer’s disease via signaling to pericytes
- (2019) Ross Nortley et al. SCIENCE
- A novel deactivation factor of fibrogenic hepatic stellate cells induces regression of liver fibrosis in mice
- (2019) Yasuhiro Nakano et al. HEPATOLOGY
- Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion
- (2019) Ansuman T. Satpathy et al. NATURE BIOTECHNOLOGY
- Gamma Interferon Alters Junctional Integrity via Rho Kinase, Resulting in Blood-Brain Barrier Leakage in Experimental Viral Encephalitis
- (2019) Stephanie Bonney et al. mBio
- Atherosclerosis
- (2019) Peter Libby et al. Nature Reviews Disease Primers
- Chronic Inflammation Within the Vascular Wall in Pulmonary Arterial Hypertension: More than a Spectator
- (2019) Alice Huertas et al. CARDIOVASCULAR RESEARCH
- CoBATCH for High-Throughput Single-Cell Epigenomic Profiling
- (2019) Qianhao Wang et al. MOLECULAR CELL
- A single-cell atlas of entorhinal cortex from individuals with Alzheimer’s disease reveals cell-type-specific gene expression regulation
- (2019) Alexandra Grubman et al. NATURE NEUROSCIENCE
- The reactome pathway knowledgebase
- (2019) Bijay Jassal et al. NUCLEIC ACIDS RESEARCH
- Involvement of Transcription Factor 21 in the Pathogenesis of Fibrosis in Endometriosis
- (2019) Umida Ganieva et al. AMERICAN JOURNAL OF PATHOLOGY
- Arterial Sca1+ Vascular Stem Cells Generate De Novo Smooth Muscle for Artery Repair and Regeneration
- (2019) Juan Tang et al. Cell Stem Cell
- Single-cell connectomic analysis of adult mammalian lungs
- (2019) Micha Sam Brickman Raredon et al. Science Advances
- SINHCAF/FAM60A and SIN3A specifically repress HIF-2α expression
- (2018) John Biddlestone et al. BIOCHEMICAL JOURNAL
- Single-Cell Transcriptome Analyses Reveal Endothelial Cell Heterogeneity in Tumors and Changes following Antiangiogenic Treatment
- (2018) Qi Zhao et al. CANCER RESEARCH
- Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine AtherosclerosisNovelty and Significance
- (2018) Clément Cochain et al. CIRCULATION RESEARCH
- Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart
- (2018) Xing Fu et al. JOURNAL OF CLINICAL INVESTIGATION
- Microvascular Mural Cell Organotypic Heterogeneity and Functional Plasticity
- (2018) Annegret Holm et al. TRENDS IN CELL BIOLOGY
- scNMT-seq enables joint profiling of chromatin accessibility DNA methylation and transcription in single cells
- (2018) Stephen J. Clark et al. Nature Communications
- Single-Cell Transcriptional Profiling Reveals Cellular Diversity and Intercommunication in the Mouse Heart
- (2018) Daniel A. Skelly et al. Cell Reports
- Vascular cognitive impairment
- (2018) Wiesje M. van der Flier et al. Nature Reviews Disease Primers
- Unraveling the Role of Angiogenesis in Cancer Ecosystems
- (2018) Iratxe Zuazo-Gaztelu et al. Frontiers in Oncology
- A molecular atlas of cell types and zonation in the brain vasculature
- (2018) Michael Vanlandewijck et al. NATURE
- The role of brain vasculature in neurodegenerative disorders
- (2018) Melanie D. Sweeney et al. NATURE NEUROSCIENCE
- Joint profiling of chromatin accessibility and gene expression in thousands of single cells
- (2018) Junyue Cao et al. SCIENCE
- Whole-Brain Vasculature Reconstruction at the Single Capillary Level
- (2018) Antonino Paolo Di Giovanna et al. Scientific Reports
- Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis
- (2018) Paul A Reyfman et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Lung Single-Cell Signaling Interaction Map Reveals Basophil Role in Macrophage Imprinting
- (2018) Merav Cohen et al. CELL
- Transcriptome Analysis Reveals Nonfoamy Rather Than Foamy Plaque Macrophages Are Proinflammatory in Atherosclerotic Murine Models
- (2018) Kyeongdae Kim et al. CIRCULATION RESEARCH
- Advantages of Single-Nucleus over Single-Cell RNA Sequencing of Adult Kidney: Rare Cell Types and Novel Cell States Revealed in Fibrosis
- (2018) Haojia Wu et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris
- (2018) et al. NATURE
- Disease-relevant transcriptional signatures identified in individual smooth muscle cells from healthy mouse vessels
- (2018) Lina Dobnikar et al. Nature Communications
- Analysis of Single-Cell RNA-Seq Identifies Cell-Cell Communication Associated with Tumor Characteristics
- (2018) Manu P. Kumar et al. Cell Reports
- The role of APOE on lipid homeostasis and inflammation in normal brains
- (2017) G. William Rebeck JOURNAL OF LIPID RESEARCH
- The Human Cell Atlas: from vision to reality
- (2017) Orit Rozenblatt-Rosen et al. NATURE
- Complex multi-enhancer contacts captured by genome architecture mapping
- (2017) Robert A. Beagrie et al. NATURE
- Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition
- (2017) Ilya M. Flyamer et al. NATURE
- 3D structures of individual mammalian genomes studied by single-cell Hi-C
- (2017) Tim J. Stevens et al. NATURE
- IRF3 and type I interferons fuel a fatal response to myocardial infarction
- (2017) Kevin R King et al. NATURE MEDICINE
- Cerebral blood flow regulation and neurovascular dysfunction in Alzheimer disease
- (2017) Kassandra Kisler et al. NATURE REVIEWS NEUROSCIENCE
- The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia
- (2017) Maria Tiana et al. NUCLEIC ACIDS RESEARCH
- Single-cell epigenomics: Recording the past and predicting the future
- (2017) Gavin Kelsey et al. SCIENCE
- The Human Cell Atlas
- (2017) Aviv Regev et al. eLife
- Simultaneous measurement of chromatin accessibility, DNA methylation, and nucleosome phasing in single cells
- (2017) Sebastian Pott eLife
- Adventitial MSC-like Cells Are Progenitors of Vascular Smooth Muscle Cells and Drive Vascular Calcification in Chronic Kidney Disease
- (2016) Rafael Kramann et al. Cell Stem Cell
- The Biological Basis for Cardiac Repair After Myocardial Infarction
- (2016) Sumanth D. Prabhu et al. CIRCULATION RESEARCH
- Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis
- (2016) Michael A. Gimbrone et al. CIRCULATION RESEARCH
- Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension
- (2016) Thomas Bertero et al. JOURNAL OF CLINICAL INVESTIGATION
- Role of metabolism in neurodegenerative disorders
- (2016) Claudio Procaccini et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability
- (2016) Solene M. Evrard et al. Nature Communications
- Cerebrovascular and blood-brain barrier impairments in Huntington's disease: Potential implications for its pathophysiology
- (2015) Janelle Drouin-Ouellet et al. ANNALS OF NEUROLOGY
- Establishment and Dysfunction of the Blood-Brain Barrier
- (2015) Zhen Zhao et al. CELL
- Single-cell chromatin accessibility reveals principles of regulatory variation
- (2015) Jason D. Buenrostro et al. NATURE
- KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis
- (2015) Laura S Shankman et al. NATURE MEDICINE
- Single-cell Hi-C for genome-wide detection of chromatin interactions that occur simultaneously in a single cell
- (2015) Takashi Nagano et al. Nature Protocols
- Vascular parkinsonism—characteristics, pathogenesis and treatment
- (2015) Amos D. Korczyn Nature Reviews Neurology
- Multiplex single-cell profiling of chromatin accessibility by combinatorial cellular indexing
- (2015) D. A. Cusanovich et al. SCIENCE
- The Blood–Brain Barrier
- (2015) Richard Daneman et al. Cold Spring Harbor Perspectives in Biology
- A draft network of ligand–receptor-mediated multicellular signalling in human
- (2015) Jordan A. Ramilowski et al. Nature Communications
- Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap
- (2015) Sylvia T. Nurnberg et al. PLoS Genetics
- Macrophage Proliferation in Atherosclerosis
- (2014) Michael E. Rosenfeld ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Transdifferentiation of Vascular Smooth Muscle Cells to Macrophage-Like Cells During Atherogenesis
- (2014) Susanne Feil et al. CIRCULATION RESEARCH
- Endothelial Dysfunction and Hypertension
- (2014) Ralf P. Brandes HYPERTENSION
- The metabolic evaluation of the child with an intellectual developmental disorder: Diagnostic algorithm for identification of treatable causes and new digital resource
- (2014) Clara D.M. van Karnebeek et al. MOLECULAR GENETICS AND METABOLISM
- Capillary pericytes regulate cerebral blood flow in health and disease
- (2014) Catherine N. Hall et al. NATURE
- The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells
- (2014) Cole Trapnell et al. NATURE BIOTECHNOLOGY
- Atrial Identity Is Determined by a COUP-TFII Regulatory Network
- (2013) San-pin Wu et al. DEVELOPMENTAL CELL
- Differential expression of embryonic epicardial progenitor markers and localization of cardiac fibrosis in adult ischemic injury and hypertensive heart disease
- (2013) Caitlin M. Braitsch et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Updated Clinical Classification of Pulmonary Hypertension
- (2013) Gerald Simonneau et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Development, maintenance and disruption of the blood-brain barrier
- (2013) Birgit Obermeier et al. NATURE MEDICINE
- The Pathobiology of Vascular Dementia
- (2013) Costantino Iadecola NEURON
- Pericyte loss influences Alzheimer-like neurodegeneration in mice
- (2013) Abhay P. Sagare et al. Nature Communications
- Blood–spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis
- (2012) Ethan A. Winkler et al. ACTA NEUROPATHOLOGICA
- The angiogenesis suppressor gene AKAP12 is under the epigenetic control of HDAC7 in endothelial cells
- (2012) Andrei Turtoi et al. ANGIOGENESIS
- Deficiency in Mural Vascular Cells Coincides with Blood-Brain Barrier Disruption in Alzheimer's Disease
- (2012) Jesse D. Sengillo et al. BRAIN PATHOLOGY
- Smooth muscle cell phenotypic switching in atherosclerosis
- (2012) D. Gomez et al. CARDIOVASCULAR RESEARCH
- Genome-wide mapping of nucleosome positioning and DNA methylation within individual DNA molecules
- (2012) T. K. Kelly et al. GENOME RESEARCH
- Endothelial dysfunction and hypertension in aging
- (2012) Yukihito Higashi et al. HYPERTENSION RESEARCH
- An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension
- (2012) Jongmin Kim et al. NATURE MEDICINE
- Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis
- (2012) Alfiya Akhmetshina et al. Nature Communications
- Pericytes: Developmental, Physiological, and Pathological Perspectives, Problems, and Promises
- (2011) Annika Armulik et al. DEVELOPMENTAL CELL
- Class IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactin
- (2011) David Kaluza et al. EMBO JOURNAL
- Disruption of PPARγ/β-catenin–mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survival
- (2011) Tero-Pekka Alastalo et al. JOURNAL OF CLINICAL INVESTIGATION
- Atherosclerosis: current pathogenesis and therapeutic options
- (2011) Christian Weber et al. NATURE MEDICINE
- Pericyte-specific expression of PDGF beta receptor in mouse models with normal and deficient PDGF beta receptor signaling
- (2010) Ethan A Winkler et al. Molecular Neurodegeneration
- Pericytes are required for blood–brain barrier integrity during embryogenesis
- (2010) Richard Daneman et al. NATURE
- Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging
- (2010) Robert D. Bell et al. NEURON
- Thrombin Stimulates Smooth Muscle Cell Differentiation From Peripheral Blood Mononuclear Cells via Protease-Activated Receptor-1, RhoA, and Myocardin
- (2009) Kenneth Martin et al. CIRCULATION RESEARCH
- Detachment of Brain Pericytes from the Basal Lamina is Involved in Disruption of the Blood–Brain Barrier Caused by Lipopolysaccharide-Induced Sepsis in Mice
- (2008) Tsuyoshi Nishioku et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Substrate-induced phenotypical change of monocytes/macrophages into myofibroblast-like cells: A new insight into the mechanism of in-stent restenosis
- (2008) H. J. S. Stewart et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
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