The role of APOE on lipid homeostasis and inflammation in normal brains
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Title
The role of APOE on lipid homeostasis and inflammation in normal brains
Authors
Keywords
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Journal
JOURNAL OF LIPID RESEARCH
Volume 58, Issue 8, Pages 1493-1499
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2017-03-04
DOI
10.1194/jlr.r075408
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Note: Only part of the references are listed.- Alzheimer's Disease Genetic Risk Factor APOE-ε4 Also Affects Normal Brain Function
- (2016) Amanda M. Di Battista et al. Current Alzheimer Research
- Identification and modification of amyloid-independent phenotypes of APOE4 mice
- (2016) Amanda M. DiBattista et al. EXPERIMENTAL NEUROLOGY
- ABCA1 Agonist Reverses the ApoE4-Driven Cognitive and Brain Pathologies
- (2016) Anat Boehm-Cagan et al. JOURNAL OF ALZHEIMERS DISEASE
- Apolipoprotein E Genotype Affects Size of ApoE Complexes in Cerebrospinal Fluid
- (2016) Nicolette Mary Heinsinger et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- The Effect of theAPOE4Gene on Accumulation of Aβ40After Brain Injury Cannot Be Reversed by Increasing apoE4 Protein
- (2016) Patricia M. Washington et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Apolipoprotein E4 Causes Age-Dependent Disruption of Slow Gamma Oscillations during Hippocampal Sharp-Wave Ripples
- (2016) Anna K. Gillespie et al. NEURON
- TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia
- (2016) Felix L. Yeh et al. NEURON
- LXR Regulation of Brain Cholesterol: From Development to Disease
- (2016) Rebecca Courtney et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Role of Liver X Receptor in AD Pathophysiology
- (2016) Adrián G. Sandoval-Hernández et al. PLoS One
- Alzheimer’s Disease Risk Genes and Mechanisms of Disease Pathogenesis
- (2015) Celeste M. Karch et al. BIOLOGICAL PSYCHIATRY
- Prevalence of Cerebral Amyloid Pathology in Persons Without Dementia
- (2015) Willemijn J. Jansen et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2)
- (2015) Yuka Atagi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Apolipoprotein E4 reduces evoked hippocampal acetylcholine release in adult mice
- (2015) Eva Dolejší et al. JOURNAL OF NEUROCHEMISTRY
- ABCA1 is Necessary for Bexarotene-Mediated Clearance of Soluble Amyloid Beta from the Hippocampus of APP/PS1 Mice
- (2015) Angela W. Corona et al. Journal of Neuroimmune Pharmacology
- Opposing effects of viral mediated brain expression of apolipoprotein E2 (apoE2) and apoE4 on apoE lipidation and Aβ metabolism in apoE4-targeted replacement mice
- (2015) Jin Hu et al. Molecular Neurodegeneration
- Genetics ignite focus on microglial inflammation in Alzheimer’s disease
- (2015) Manasi Malik et al. Molecular Neurodegeneration
- Reduced grid-cell-like representations in adults at genetic risk for Alzheimer's disease
- (2015) L. Kunz et al. SCIENCE
- Involvement of the Apoer2 and Lrp1 receptors in mediating the pathological effects of ApoE4 in vivo
- (2014) Moran Gilat-Frenkel et al. Current Alzheimer Research
- Apolipoproteins E and J interfere with amyloid-beta uptake by primary human astrocytes and microgliain vitro
- (2014) Sandra D. Mulder et al. GLIA
- Human APOE4 increases microglia reactivity at Aβ plaques in a mouse model of Aβ deposition
- (2014) Gustavo A Rodriguez et al. Journal of Neuroinflammation
- Apolipoprotein E4 Produced in GABAergic Interneurons Causes Learning and Memory Deficits in Mice
- (2014) J. Knoferle et al. JOURNAL OF NEUROSCIENCE
- Reversal of apoE4-Driven Brain Pathology and Behavioral Deficits by Bexarotene
- (2014) A. Boehm-Cagan et al. JOURNAL OF NEUROSCIENCE
- Liver X receptors in lipid metabolism: opportunities for drug discovery
- (2014) Cynthia Hong et al. NATURE REVIEWS DRUG DISCOVERY
- Altered neurotransmission in the lateral amygdala in aged human apoE4 targeted replacement mice
- (2014) Rebecca C. Klein et al. NEUROBIOLOGY OF AGING
- ATP-binding cassette transporter A1: From metabolism to neurodegeneration
- (2014) Radosveta Koldamova et al. NEUROBIOLOGY OF DISEASE
- The Evolution of Preclinical Alzheimer’s Disease: Implications for Prevention Trials
- (2014) Reisa Sperling et al. NEURON
- A combined effect of two Alzheimer's risk genes on medial temporal activity during executive attention in young adults
- (2014) Adam E. Green et al. NEUROPSYCHOLOGIA
- A gene−brain−cognition pathway for the effect of an Alzheimer׳s risk gene on working memory in young adults
- (2014) Benson W. Stevens et al. NEUROPSYCHOLOGIA
- Common Variants in Psychiatric Risk Genes Predict Brain Structure at Birth
- (2013) R. C. Knickmeyer et al. CEREBRAL CORTEX
- Young APOE4 targeted replacement mice exhibit poor spatial learning and memory, with reduced dendritic spine density in the medial entorhinal cortex
- (2013) G. A. Rodriguez et al. LEARNING & MEMORY
- Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy
- (2013) Chia-Chen Liu et al. Nature Reviews Neurology
- Differential effects of the ApoE4 genotype on brain structure and function
- (2013) Silke Matura et al. NEUROIMAGE
- Apolipoprotein E4 Causes Age- and Sex-Dependent Impairments of Hilar GABAergic Interneurons and Learning and Memory Deficits in Mice
- (2013) Laura Leung et al. PLoS One
- Effect of Apolipoprotein E Genotype and Diet on Apolipoprotein E Lipidation and Amyloid Peptides
- (2013) Angela J. Hanson et al. JAMA Neurology
- Brain Differences in Infants at Differential Genetic Risk for Late-Onset Alzheimer Disease
- (2013) Douglas C. Dean et al. JAMA Neurology
- ApolipoproteinE mimetic peptides improve outcome after focal ischemia
- (2012) Haichen Wang et al. EXPERIMENTAL NEUROLOGY
- APOE genotype alters glial activation and loss of synaptic markers in mice
- (2012) Yuangui Zhu et al. GLIA
- Cerebrospinal fluid APOE levels: an endophenotype for genetic studies for Alzheimer's disease
- (2012) Carlos Cruchaga et al. HUMAN MOLECULAR GENETICS
- APOE genotype affects the pre-synaptic compartment of glutamatergic nerve terminals
- (2012) Sonya B. Dumanis et al. JOURNAL OF NEUROCHEMISTRY
- APOE e4 polymorphism in young adults is associated with improved attention and indexed by distinct neural signatures
- (2012) J.M. Rusted et al. NEUROIMAGE
- Variant of TREM2 Associated with the Risk of Alzheimer's Disease
- (2012) Thorlakur Jonsson et al. NEW ENGLAND JOURNAL OF MEDICINE
- Reduced Hippocampal Volume in Healthy Young ApoE4 Carriers: An MRI Study
- (2012) Laurence O'Dwyer et al. PLoS One
- ApoE-Directed Therapeutics Rapidly Clear -Amyloid and Reverse Deficits in AD Mouse Models
- (2012) P. E. Cramer et al. SCIENCE
- Extended results of the Alzheimer’s disease anti-inflammatory prevention trial
- (2011) John C. Breitner et al. Alzheimers & Dementia
- Apolipoprotein E Induces Antiinflammatory Phenotype in Macrophages
- (2011) Daniel Baitsch et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- C-terminal-truncated apolipoprotein (apo) E4 inefficiently clears amyloid- (A ) and acts in concert with A to elicit neuronal and behavioral deficits in mice
- (2011) N. Bien-Ly et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human apoE Isoforms Differentially Regulate Brain Amyloid- Peptide Clearance
- (2011) J. M. Castellano et al. Science Translational Medicine
- Meta-analysis Confirms CR1, CLU, and PICALM as Alzheimer Disease Risk Loci and Reveals Interactions With APOE Genotypes
- (2010) Gyungah Jun ARCHIVES OF NEUROLOGY
- ATP-binding Cassette Transporter A1 Mediates the Beneficial Effects of the Liver X Receptor Agonist GW3965 on Object Recognition Memory and Amyloid Burden in Amyloid Precursor Protein/Presenilin 1 Mice
- (2010) James J. Donkin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Age-Dependent Effect of Apolipoprotein E4 on Functional Outcome after Controlled Cortical Impact in Mice
- (2010) Rebekah C Mannix et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Progressive loss of synaptic integrity in human apolipoprotein E4 targeted replacement mice and attenuation by apolipoprotein E2
- (2010) R.C. Klein et al. NEUROSCIENCE
- Apolipoprotein E4 and Sex Affect Neurobehavioral Performance in Primary School Children
- (2010) Summer F Acevedo et al. PEDIATRIC RESEARCH
- APOE 4 polymorphism results in early cognitive deficits in an EAE model
- (2009) Jiang-long Tu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Inhibition of c-Jun N-terminal kinase increases apoE expression in vitro and in vivo
- (2009) Ana Pocivavsek et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Microglial low-density lipoprotein receptor-related protein 1 modulates c-Jun N-terminal kinase activation
- (2009) Ana Pocivavsek et al. JOURNAL OF NEUROIMMUNOLOGY
- ApoE4 Decreases Spine Density and Dendritic Complexity in Cortical Neurons In Vivo
- (2009) S. B. Dumanis et al. JOURNAL OF NEUROSCIENCE
- Mechanism underlying apolipoprotein E (ApoE) isoform-dependent lipid efflux from neural cells in culture
- (2009) Hirohisa Minagawa et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
- (2009) Jean-Charles Lambert et al. NATURE GENETICS
- Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
- (2009) Denise Harold et al. NATURE GENETICS
- Reduced levels of human apoE4 protein in an animal model of cognitive impairment
- (2009) P.M. Sullivan et al. NEUROBIOLOGY OF AGING
- Revision of the apolipoprotein E compensatory mechanism recruitment hypothesis
- (2008) S. Duke Han et al. Alzheimers & Dementia
- Middle-aged human apoE4 targeted-replacement mice show retention deficits on a wide range of spatial memory tasks
- (2008) Alexandra Bour et al. BEHAVIOURAL BRAIN RESEARCH
- Low-density lipoprotein receptors regulate microglial inflammation through c-Jun N-terminal kinase
- (2008) Ana Pocivavsek et al. GLIA
- Impact of Apolipoprotein E (ApoE) Polymorphism on Brain ApoE Levels
- (2008) D. R. Riddell et al. JOURNAL OF NEUROSCIENCE
- Anatomically-distinct genetic associations of APOE ɛ4 allele load with regional cortical atrophy in Alzheimer's disease
- (2008) Nicola Filippini et al. NEUROIMAGE
- Pharmacogenomic Effects of Apolipoprotein E on Intracerebral Hemorrhage
- (2008) Michael L. James et al. STROKE
- Altered medial temporal lobe responses during visuospatial encoding in healthy APOE*4 carriers
- (2007) Paul R. Borghesani et al. NEUROBIOLOGY OF AGING
- APOE genotype-specific differences in the innate immune response
- (2007) Michael P. Vitek et al. NEUROBIOLOGY OF AGING
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