Advances in DNA Repair—Emerging Players in the Arena of Eukaryotic DNA Repair

Helix–loop–helix proteins and the advent of cellular diversity: 30 years of discovery

(2019) Cornelis Murre   GENES & DEVELOPMENT

Influence of the extracellular matrix on cell-intrinsic circadian clocks

(2019) Charles H. Streuli et al.   JOURNAL OF CELL SCIENCE

Circadian (De)regulation in Head and Neck Squamous Cell Carcinoma

(2019) Sadia Rahman et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The role of circadian clock genes in tumors

(2019) Han-Xue Li   OncoTargets and Therapy

Circadian rhythms in the three-dimensional genome: implications of chromatin interactions for cyclic transcription

(2019) Ignacio Pacheco-Bernal et al.   Clinical Epigenetics

Protection of abasic sites during DNA replication by a stable thiazolidine protein-DNA cross-link

(2019) Petria S. Thompson et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition

(2019) Levon Halabelian et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Emerging Roles of RAD52 in Genome Maintenance

(2019) Manisha Jalan et al.   Cancers

Heat-shock proteins: chaperoning DNA repair

(2019) Laurence Dubrez et al.   ONCOGENE

SIRT5 Promotes Cisplatin Resistance in Ovarian Cancer by Suppressing DNA Damage in a ROS-Dependent Manner via Regulation of the Nrf2/HO-1 Pathway

(2019) Xiaodan Sun et al.   Frontiers in Oncology

Poly(ADP-ribose) polymerase enzymes and the maintenance of genome integrity

(2019) Travis Eisemann et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Multiple roles of DNA2 nuclease/helicase in DNA metabolism, genome stability and human diseases

(2019) Li Zheng et al.   NUCLEIC ACIDS RESEARCH

Translesion Synthesis in Plants: Ultraviolet Resistance and Beyond

(2019) Ayako N. Sakamoto   Frontiers in Plant Science

HMCES Functions in the Alternative End-Joining Pathway of the DNA DSB Repair during Class Switch Recombination in B Cells

(2019) Vipul Shukla et al.   MOLECULAR CELL

DSS1 interacts with and stimulates RAD52 to promote the repair of DSBs

(2019) Barbora Stefanovie et al.   NUCLEIC ACIDS RESEARCH

Long non-coding RNA MALAT1 interacts with transcription factor Foxo1 to regulate SIRT1 transcription in high glucose-induced HK-2 cells injury

(2018) Ling Zhou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Long non-coding RNA TUG1 protects renal tubular epithelial cells against injury induced by lipopolysaccharide via regulating microRNA-223

(2018) Yan Xu et al.   BIOMEDICINE & PHARMACOTHERAPY

GUARDIN is a p53-responsive long non-coding RNA that is essential for genomic stability

(2018) Wang Lai Hu et al.   NATURE CELL BIOLOGY

Effect of Neoadjuvant Chemotherapy Plus Regional Hyperthermia on Long-term Outcomes Among Patients With Localized High-Risk Soft Tissue Sarcoma

(2018) Rolf D. Issels et al.   JAMA Oncology

HMCES Maintains Genome Integrity by Shielding Abasic Sites in Single-Strand DNA

(2018) Kareem N. Mohni et al.   CELL

The long noncoding RNA NEAT1 and nuclear paraspeckles are up-regulated by the transcription factor HSF1 in the heat shock response

(2018) S. Mohammad Lellahi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of DNA Double-Strand Break Repair by Non-Coding RNAs

(2018) Roopa Thapar   MOLECULES

HSP110 translocates to the nucleus upon genotoxic chemotherapy and promotes DNA repair in colorectal cancer cells

(2018) Sebastien Z. Causse et al.   ONCOGENE

Sirt1 Antisense Long Noncoding RNA Promotes Cardiomyocyte Proliferation by Enhancing the Stability of Sirt1

(2018) Bing Li et al.   Journal of the American Heart Association

Mechanisms of DNA damage, repair, and mutagenesis

(2017) Nimrat Chatterjee et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

DNA2—An Important Player in DNA Damage Response or Just Another DNA Maintenance Protein?

(2017) Elzbieta Pawłowska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A class of circadian long non-coding RNAs mark enhancers modulating long-range circadian gene regulation

(2017) Zenghua Fan et al.   NUCLEIC ACIDS RESEARCH

Long Noncoding RNA PURPL Suppresses Basal p53 Levels and Promotes Tumorigenicity in Colorectal Cancer

(2017) Xiao Ling Li et al.   Cell Reports

Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3

(2017) Ritu Chaudhary et al.   eLife

SIRT1 Enhances the Survival of Human Embryonic Stem Cells by Promoting DNA Repair

(2017) Jiho Jang et al.   Stem Cell Reports

SIRT7 promotes genome integrity and modulates non‐homologous end joining DNA repair

(2016) Berta N Vazquez et al.   EMBO JOURNAL

An inducible long noncoding RNA amplifies DNA damage signaling

(2016) Adam M Schmitt et al.   NATURE GENETICS

p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity

(2016) Carmen Adriaens et al.   NATURE MEDICINE

Nuclear DNA damage signalling to mitochondria in ageing

(2016) Evandro Fei Fang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Long noncoding RNA LINP1 regulates repair of DNA double-strand breaks in triple-negative breast cancer

(2016) Youyou Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

NF-κB-HOTAIR axis links DNA damage response, chemoresistance and cellular senescence in ovarian cancer

(2016) A R Özeş et al.   ONCOGENE

Regional hyperthermia combined with chemotherapy in paediatric, adolescent and young adult patients: current and future perspectives

(2016) Georg Seifert et al.   Radiation Oncology

Linking Long Noncoding RNA Localization and Function

(2016) Ling-Ling Chen   TRENDS IN BIOCHEMICAL SCIENCES

Long noncoding RNA LINP1 regulates repair of DNA double-strand breaks in triple-negative breast cancer

(2016) Youyou Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ATM is the primary kinase responsible for phosphorylation of Hsp90α after ionizing radiation

(2016) Ameer L. Elaimy et al.   Oncotarget

Effects of different fluid replacements on serum HSP70 and lymphocyte DNA damage in college athletes during exercise at high ambient temperatures

(2016) Hee-Tae Roh et al.   Journal of Sport and Health Science

SIRT6 stabilizes DNA-dependent Protein Kinase at chromatin for DNA double-strand break repair

(2016) Ronald A. McCord et al.   Aging-US

Sirtuin regulation in aging and injury

(2015) Ninu Poulose et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The role of Hsp70 in oxi-inflamm-aging and its use as a potential biomarker of lifespan

(2015) I. Martínez de Toda et al.   BIOGERONTOLOGY

SIRT6 protein deacetylase interacts with MYH DNA glycosylase, APE1 endonuclease, and Rad9–Rad1–Hus1 checkpoint clamp

(2015) Bor-Jang Hwang et al.   BMC MOLECULAR BIOLOGY

A BRCA1-interacting lncRNA regulates homologous recombination

(2015) V. Sharma et al.   EMBO REPORTS

Hyperthermia effects on Hsp27 and Hsp72 associations with mismatch repair (MMR) proteins and cisplatin toxicity in MMR-deficient/proficient colon cancer cell lines

(2015) Mayra L. Sottile et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Regional hyperthermia and moderately dose-escalated salvage radiotherapy for recurrent prostate cancer. Protocol of a phase II trial

(2015) Arndt-Christian Müller et al.   Radiation Oncology

Altered expression of LINC-ROR in cancer cell lines and tissues

(2015) Majdaddin Rezaei et al.   TUMOR BIOLOGY

A Long Noncoding RNA Perturbs the Circadian Rhythm of Hepatoma Cells to Facilitate Hepatocarcinogenesis

(2015) Ming Cui et al.   NEOPLASIA

KAP1 Deacetylation by SIRT1 Promotes Non-Homologous End-Joining Repair

(2015) Yi-Hui Lin et al.   PLoS One

TODRA, a lncRNA at the RAD51 Locus, Is Oppositely Regulated to RAD51, and Enhances RAD51-Dependent DSB (Double Strand Break) Repair

(2015) Inbal Gazy et al.   PLoS One

A novel antisense long noncoding RNA regulates the expression of MDC1 in bladder cancer

(2015) Yao Xue et al.   Oncotarget

PCAT-1 , a Long Noncoding RNA, Regulates BRCA2 and Controls Homologous Recombination in Cancer

(2014) John R. Prensner et al.   CANCER RESEARCH

Partitioning Circadian Transcription by SIRT6 Leads to Segregated Control of Cellular Metabolism

(2014) Selma Masri et al.   CELL

Down-regulation of MSH2 expression by an Hsp90 inhibitor enhances pemetrexed-induced cytotoxicity in human non-small-cell lung cancer cells

(2014) Chun-Liang Tung et al.   EXPERIMENTAL CELL RESEARCH

Long non-coding RNA and microRNAs might act in regulating the expression of BARD1 mRNAs

(2014) Maxim Pilyugin et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Reactive oxygen species, heat stress and oxidative-induced mitochondrial damage. A review

(2014) Imen Belhadj Slimen et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Prolonged Fasting Identifies Heat Shock Protein 10 as a Sirtuin 3 Substrate

(2014) Zhongping Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HSP90 Affects the Stability of BMAL1 and Circadian Gene Expression

(2014) Rebecca Schneider et al.   JOURNAL OF BIOLOGICAL RHYTHMS

The Functional Landscape of Hsp27 Reveals New Cellular Processes such as DNA Repair and Alternative Splicing and Proposes Novel Anticancer Targets

(2014) Maria Katsogiannou et al.   MOLECULAR & CELLULAR PROTEOMICS

Long intergenic non-coding RNA induced by X-ray irradiation regulates DNA damage response signaling in the human bronchial epithelial BEAS-2B cell line

(2014) YANG JIAO et al.   Oncology Letters

HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β

(2014) Qingming Fang et al.   Nature Communications

Genome-wide analysis of the human p53 transcriptional network unveils a lncRNA tumour suppressor signature

(2014) Yolanda Sánchez et al.   Nature Communications

TERRA-Reinforced Association of LSD1 with MRE11 Promotes Processing of Uncapped Telomeres

(2014) Antonio Porro et al.   Cell Reports

The Long Non-Coding RNA PCAT-1 Promotes Prostate Cancer Cell Proliferation through cMyc

(2014) John R. Prensner et al.   NEOPLASIA

Histone deacetylase SIRT1 modulates and deacetylates DNA base excision repair enzyme thymine DNA glycosylase

(2013) Amrita Madabushi et al.   BIOCHEMICAL JOURNAL

Non-coding RNAs turn up the heat: An emerging layer of novel regulators in the mammalian heat shock response

(2013) Robert F. Place et al.   CELL STRESS & CHAPERONES

Long non-coding RNA ANRIL (CDKN2B-AS) is induced by the ATM-E2F1 signaling pathway

(2013) Guohui Wan et al.   CELLULAR SIGNALLING

A novel non-coding RNA lncRNA-JADE connects DNA damage signalling to histone H4 acetylation

(2013) Guohui Wan et al.   EMBO JOURNAL

Molecular targets and mechanisms of radiosensitization using DNA damage response pathways

(2013) David R Raleigh et al.   Future Oncology

The tumor suppressor SirT2 regulates cell cycle progression and genome stability by modulating the mitotic deposition of H4K20 methylation

(2013) L. Serrano et al.   GENES & DEVELOPMENT

Inhibition of Hsp27 Radiosensitizes Head-and-Neck Cancer by Modulating Deoxyribonucleic Acid Repair

(2013) David M. Guttmann et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

SIRT6 Recruits SNF2H to DNA Break Sites, Preventing Genomic Instability through Chromatin Remodeling

(2013) Debra Toiber et al.   MOLECULAR CELL

DNA damage associated with mitosis and cytokinesis failure

(2013) M T Hayashi et al.   ONCOGENE

SIRT2 directs the replication stress response through CDK9 deacetylation

(2013) H. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pint lincRNA connects the p53 pathway with epigenetic silencing by the Polycomb repressive complex 2

(2013) Oskar Marín-Béjar et al.   GENOME BIOLOGY

Central and Peripheral Circadian Clocks in Mammals

(2012) Jennifer A. Mohawk et al.   Annual Review of Neuroscience

DNA damage-induced cell death: From specific DNA lesions to the DNA damage response and apoptosis

(2012) Wynand P. Roos et al.   CANCER LETTERS

Ferruccio Ritossa’s scientific legacy 50 years after his discovery of the heat shock response: a new view of biology, a new society, and a new journal

(2012) Antonio De Maio et al.   CELL STRESS & CHAPERONES

Long non-coding RNAgadd7interacts with TDP-43 and regulatesCdk6mRNA decay

(2012) Xuefeng Liu et al.   EMBO JOURNAL

Effects of hyperthermia on Hsp27 (HSPB1), Hsp72 (HSPA1A) and DNA repair proteins hMLH1 and hMSH2 in human colorectal cancer hMLH1-deficient and hMLH1-proficient cell lines

(2012) Silvina B. Nadin et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Regulation of DNA-End Resection by hnRNPU-like Proteins Promotes DNA Double-Strand Break Signaling and Repair

(2012) Sophie E. Polo et al.   MOLECULAR CELL

SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation

(2012) Matthew F. Barber et al.   NATURE

Heat shock protein 90  (HSP90 ), a substrate and chaperone of DNA-PK necessary for the apoptotic response

(2012) S. Solier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA Regulation of SIRT1

(2012) Munekazu Yamakuchi   Frontiers in Physiology

Long Intergenic Noncoding RNAs: New Links in Cancer Progression

(2011) M.-C. Tsai et al.   CANCER RESEARCH

Hsp90 Inhibitor-Mediated Disruption of Chaperone Association of ATR with Hsp90 Sensitizes Cancer Cells to DNA Damage

(2011) K. Ha et al.   MOLECULAR CANCER THERAPEUTICS

SIRT3 Deficiency and Mitochondrial Protein Hyperacetylation Accelerate the Development of the Metabolic Syndrome

(2011) Matthew D. Hirschey et al.   MOLECULAR CELL

Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression

(2011) John R Prensner et al.   NATURE BIOTECHNOLOGY

Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters

(2011) Tiffany Hung et al.   NATURE GENETICS

SIRT6 Promotes DNA Repair Under Stress by Activating PARP1

(2011) Z. Mao et al.   SCIENCE

Mammalian Sirtuins: Biological Insights and Disease Relevance

(2010) Marcia C. Haigis et al.   Annual Review of Pathology-Mechanisms of Disease

SIRT1 and p53, effect on cancer, senescence and beyond

(2010) Jingjie Yi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction

(2010) Shinichi Someya et al.   CELL

A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

(2010) Maite Huarte et al.   CELL

SIRT1 is a redox-sensitive deacetylase that is post-translationally modified by oxidants and carbonyl stress

(2010) Samuel Caito et al.   FASEB JOURNAL

Circadian clock control of the cellular response to DNA damage

(2010) Aziz Sancar et al.   FEBS LETTERS

SIRT1 Regulates UV-Induced DNA Repair through Deacetylating XPA

(2010) Wei Fan et al.   MOLECULAR CELL

Heat shock factors: integrators of cell stress, development and lifespan

(2010) Malin Åkerfelt et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum C

(2010) M. Ming et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chromatin regulation and genome maintenance by mammalian SIRT6

(2010) Ruth I. Tennen et al.   TRENDS IN BIOCHEMICAL SCIENCES

Wrap53, a Natural p53 Antisense Transcript Required for p53 Induction upon DNA Damage

(2009) Salah Mahmoudi et al.   MOLECULAR CELL

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

SIRT1 deacetylates APE1 and regulates cellular base excision repair

(2009) Tohru Yamamori et al.   NUCLEIC ACIDS RESEARCH

CK2 Is the Regulator of SIRT1 Substrate-Binding Affinity, Deacetylase Activity and Cellular Response to DNA-Damage

(2009) Hyeog Kang et al.   PLoS One

Stress-Inducible Regulation of Heat Shock Factor 1 by the Deacetylase SIRT1

(2009) S. D. Westerheide et al.   SCIENCE

Correlations and co-localizations of Hsp70 with XPA, XPG in human bronchial epithelia cells exposed to benzo[a]pyrene

(2009) Jin Yang et al.   TOXICOLOGY

Impaired DNA Damage Response, Genome Instability, and Tumorigenesis in SIRT1 Mutant Mice

(2008) Rui-Hong Wang et al.   CANCER CELL

SIRT1 Redistribution on Chromatin Promotes Genomic Stability but Alters Gene Expression during Aging

(2008) Philipp Oberdoerffer et al.   CELL

The NAD+-Dependent Deacetylase SIRT1 Modulates CLOCK-Mediated Chromatin Remodeling and Circadian Control

(2008) Yasukazu Nakahata et al.   CELL

SIRT1 Regulates Circadian Clock Gene Expression through PER2 Deacetylation

(2008) Gad Asher et al.   CELL

Hsp70 translocates to the nuclei and nucleoli, binds to XRCC1 and PARP-1, and protects HeLa cells from single-strand DNA breaks

(2008) Polychronis Kotoglou et al.   CELL STRESS & CHAPERONES

Sirt7 Increases Stress Resistance of Cardiomyocytes and Prevents Apoptosis and Inflammatory Cardiomyopathy in Mice

(2008) Olesya Vakhrusheva et al.   CIRCULATION RESEARCH

Differential display of DNA-binding proteins reveals heat-shock factor 1 as a circadian transcription factor

(2008) H. Reinke et al.   GENES & DEVELOPMENT

Regulation of WRN Protein Cellular Localization and Enzymatic Activities by SIRT1-mediated Deacetylation

(2008) Kai Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SIRT3 Is a Stress-Responsive Deacetylase in Cardiomyocytes That Protects Cells from Stress-Mediated Cell Death by Deacetylation of Ku70

(2008) N. R. Sundaresan et al.   MOLECULAR AND CELLULAR BIOLOGY

DBC1 is a negative regulator of SIRT1

(2008) Ja-Eun Kim et al.   NATURE

Phosphorylation Regulates SIRT1 Function

(2008) Tsutomu Sasaki et al.   PLoS One