Regulation of DNA Double-Strand Break Repair by Non-Coding RNAs

Exosome-packaged miR-1246 contributes to bystander DNA damage by targeting LIG4

(2018) Li-Jun Mo et al.   BRITISH JOURNAL OF CANCER

Long noncoding RNA LINP1 acts as an oncogene and promotes chemoresistance in breast cancer

(2018) Yiran Liang et al.   CANCER BIOLOGY & THERAPY

Metazoan MicroRNAs

(2018) David P. Bartel   CELL

LINP1 facilitates DNA damage repair through non-homologous end joining (NHEJ) pathway and subsequently decreases the sensitivity of cervical cancer cells to ionizing radiation

(2018) Xuanxuan Wang et al.   CELL CYCLE

Repair of DNA double-strand breaks by mammalian alternative end-joining pathways

(2018) Annahita Sallmyr et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Homologous recombination and the repair of DNA double-strand breaks

(2018) William Douglass Wright et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Introduction to the Thematic Minireview Series: DNA double-strand break repair and pathway choice

(2018) Patrick Sung   JOURNAL OF BIOLOGICAL CHEMISTRY

How cells ensure correct repair of DNA double-strand breaks

(2018) Joonyoung Her et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting the MALAT1/PARP1/LIG3 complex induces DNA damage and apoptosis in multiple myeloma

(2018) Yi Hu et al.   LEUKEMIA

Dissection of DNA double-strand-break repair using novel single-molecule forceps

(2018) Jing L. Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Beyond PARP—POLθ as an anticancer target

(2018) Geoff S. Higgins et al.   SCIENCE

LncRNAs in vascular biology and disease

(2018) Viorel Simion et al.   VASCULAR PHARMACOLOGY

lincROR influences the stemness and crizotinib resistance in EML–ALK+ non-small-cell lung cancer cells

(2018) Yonghua Yang et al.   OncoTargets and Therapy

Drosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair

(2018) Wei-Ting Lu et al.   Nature Communications

Dissection of DNA double-strand-break repair using novel single-molecule forceps

(2018) Jing L. Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Localization Microscopy Analyses of MRE11 Clusters in 3D-Conserved Cell Nuclei of Different Cell Lines

(2018) Marion Eryilmaz et al.   Cancers

Shelterin-Mediated Telomere Protection

(2018) Titia de Lange   Annual Review of Genetics

Chromosome Dynamics in Response to DNA Damage

(2018) Andrew Seeber et al.   Annual Review of Genetics

LINC-PINT Activates the Mitogen-Activated Protein Kinase Pathway to Promote Acute Myocardial Infarction by Regulating miR-208a-3p

(2018) Jianzhong Zhu et al.   CIRCULATION JOURNAL

LncRNAs expression profile in peripheral blood mononuclear cells from multiple sclerosis patients

(2018) Chiara Fenoglio et al.   JOURNAL OF NEUROIMMUNOLOGY

20 Years of Mre11 Biology: No End in Sight

(2018) Tanya T. Paull   MOLECULAR CELL

The Evf2 Ultraconserved Enhancer lncRNA Functionally and Spatially Organizes Megabase Distant Genes in the Developing Forebrain

(2018) Ivelisse Cajigas et al.   MOLECULAR CELL

Ribonucleotide incorporation enables repair of chromosome breaks by nonhomologous end joining

(2018) John M. Pryor et al.   SCIENCE

Mechanisms of DNA damage, repair, and mutagenesis

(2017) Nimrat Chatterjee et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

APELA promotes tumour growth and cell migration in ovarian cancer in a p53-dependent manner

(2017) Yuyin Yi et al.   GYNECOLOGIC ONCOLOGY

Nonhomologous DNA end-joining for repair of DNA double-strand breaks

(2017) Nicholas R. Pannunzio et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LincRNa-p21: function and mechanism in cancer

(2017) Shaoyun Chen et al.   MEDICAL ONCOLOGY

Distinctive Patterns of Transcription and RNA Processing for Human lincRNAs

(2017) Margarita Schlackow et al.   MOLECULAR CELL

Regulation of repair pathway choice at two-ended DNA double-strand breaks

(2017) Atsushi Shibata   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation

(2017) Ruibing Chen et al.   NUCLEIC ACIDS RESEARCH

LncRNA lnc-RI regulates homologous recombination repair of DNA double-strand breaks by stabilizing RAD51 mRNA as a competitive endogenous RNA

(2017) Liping Shen et al.   NUCLEIC ACIDS RESEARCH

DNA-PKcs structure suggests an allosteric mechanism modulating DNA double-strand break repair

(2017) Bancinyane L. Sibanda et al.   SCIENCE

Long non‑coding RNA MDC1‑AS inhibits human gastric cancer cell proliferation and metastasis through an MDC1‑dependent mechanism

(2017) Yin Qin et al.   Experimental and Therapeutic Medicine

Linc-ing Circulating Long Non-coding RNAs to the Diagnosis and Malignant Prediction of Intraductal Papillary Mucinous Neoplasms of the Pancreas

(2017) Jennifer B. Permuth et al.   Scientific Reports

MDC1-AS, an antisense long noncoding RNA, regulates cell proliferation of glioma

(2016) Hongsheng Yue et al.   BIOMEDICINE & PHARMACOTHERAPY

An Intrinsically Disordered APLF Links Ku, DNA-PKcs, and XRCC4-DNA Ligase IV in an Extended Flexible Non-homologous End Joining Complex

(2016) Michal Hammel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DICER, DROSHA and DNA damage response RNAs are necessary for the secondary recruitment of DNA damage response factors

(2016) Sofia Francia et al.   JOURNAL OF CELL SCIENCE

Long noncoding RNA dysregulation in ischemic heart failure

(2016) Simona Greco et al.   Journal of Translational Medicine

Wrap53, a Natural p53 Antisense Transcript Required for p53 Induction upon DNA Damage

(2016) Salah Mahmoudi et al.   MOLECULAR CELL

An inducible long noncoding RNA amplifies DNA damage signaling

(2016) Adam M Schmitt et al.   NATURE GENETICS

Long noncoding RNA LINP1 regulates repair of DNA double-strand breaks in triple-negative breast cancer

(2016) Youyou Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Microhomology-mediated end joining is activated in irradiated human cells due to phosphorylation-dependent formation of the XRCC1 repair complex

(2016) Arijit Dutta et al.   NUCLEIC ACIDS RESEARCH

Ataxia telangiectasia: a review

(2016) Cynthia Rothblum-Oviatt et al.   Orphanet Journal of Rare Diseases

Hsa-miR-623 suppresses tumor progression in human lung adenocarcinoma

(2016) Shuang Wei et al.   Cell Death & Disease

Long noncoding RNA LINP1 regulates repair of DNA double-strand breaks in triple-negative breast cancer

(2016) Youyou Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Plasma and tumor levels of Linc-pint are diagnostic and prognostic biomarkers for pancreatic cancer

(2016) Le Li et al.   Oncotarget

Platinum and PARP Inhibitor Resistance Due to Overexpression of MicroRNA-622 in BRCA1 -Mutant Ovarian Cancer

(2016) Young Eun Choi et al.   Cell Reports

Post-transcriptional Regulation of BRCA2 through Interactions with miR-19a and miR-19b

(2016) Elena Mogilyansky et al.   Frontiers in Genetics

An Apela RNA-Containing Negative Feedback Loop Regulates p53-Mediated Apoptosis in Embryonic Stem Cells

(2015) Mangmang Li et al.   Cell Stem Cell

Evf2lncRNA/BRG1/DLX1 interactions reveal RNA-dependent inhibition of chromatin remodeling

(2015) Ivelisse Cajigas et al.   DEVELOPMENT

RNA-directed repair of DNA double-strand breaks

(2015) Yun-Gui Yang et al.   DNA REPAIR

A BRCA1-interacting lncRNA regulates homologous recombination

(2015) V. Sharma et al.   EMBO REPORTS

AnXRCC4Splice Mutation Associated With Severe Short Stature, Gonadal Failure, and Early-Onset Metabolic Syndrome

(2015) Christiaan de Bruin et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The emerging role of lncRNAs in cancer

(2015) Maite Huarte   NATURE MEDICINE

Junk DNA and the long non-coding RNA twist in cancer genetics

(2015) H Ling et al.   ONCOGENE

Telomere functions grounding on TERRA firma

(2015) Claus M. Azzalin et al.   TRENDS IN CELL BIOLOGY

Altered expression of LINC-ROR in cancer cell lines and tissues

(2015) Majdaddin Rezaei et al.   TUMOR BIOLOGY

Inducing cell growth arrest and apoptosis by silencing long non-coding RNA PCAT-1 in human bladder cancer

(2015) Li Liu et al.   TUMOR BIOLOGY

Long non-coding RNAs: emerging players in osteosarcoma

(2015) Zheng Li et al.   TUMOR BIOLOGY

Genome-wide profiling of p53-regulated enhancer RNAs uncovers a subset of enhancers controlled by a lncRNA

(2015) Nicolas Léveillé et al.   Nature Communications

By downregulating Ku80, hsa-miR-526b suppresses non-small cell lung cancer

(2015) Zun-yi Zhang et al.   Oncotarget

Telomeric repeat-containing RNA TERRA: a noncoding RNA connecting telomere biology to genome integrity

(2015) Emilio Cusanelli et al.   Frontiers in Genetics

TODRA, a lncRNA at the RAD51 Locus, Is Oppositely Regulated to RAD51, and Enhances RAD51-Dependent DSB (Double Strand Break) Repair

(2015) Inbal Gazy et al.   PLoS One

A novel antisense long noncoding RNA regulates the expression of MDC1 in bladder cancer

(2015) Yao Xue et al.   Oncotarget

The Fanconi Anemia DNA Repair Pathway: Structural and Functional Insights into a Complex Disorder

(2014) Helen Walden et al.   Annual Review of Biophysics

PCAT-1 , a Long Noncoding RNA, Regulates BRCA2 and Controls Homologous Recombination in Cancer

(2014) John R. Prensner et al.   CANCER RESEARCH

DNA double-strand break repair pathway choice and cancer

(2014) Tomas Aparicio et al.   DNA REPAIR

Non-homologous end joining: Emerging themes and unanswered questions

(2014) Sarvan Kumar Radhakrishnan et al.   DNA REPAIR

The clinical impact of deficiency in DNA non-homologous end-joining

(2014) Lisa Woodbine et al.   DNA REPAIR

Targeting the microRNA-regulating DNA damage/repair pathways in cancer

(2014) Giulia Bottai et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

The scaffold protein WRAP53β orchestrates the ubiquitin response critical for DNA double-strand break repair

(2014) Sofia Henriksson et al.   GENES & DEVELOPMENT

Long non-coding RNA and microRNAs might act in regulating the expression of BARD1 mRNAs

(2014) Maxim Pilyugin et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

LincRNA-p21 Activates p21 In cis to Promote Polycomb Target Gene Expression and to Enforce the G1/S Checkpoint

(2014) Nadya Dimitrova et al.   MOLECULAR CELL

An atlas of active enhancers across human cell types and tissues

(2014) Robin Andersson et al.   NATURE

A promoter-level mammalian expression atlas

(2014)   NATURE

Mechanisms underlying mutational signatures in human cancers

(2014) Thomas Helleday et al.   NATURE REVIEWS GENETICS

Structural insights into the stabilization of MALAT1 noncoding RNA by a bipartite triple helix

(2014) Jessica A Brown et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ATM-mediated phosphorylation of the chromatin remodeling enzyme BRG1 modulates DNA double-strand break repair

(2014) S-J Kwon et al.   ONCOGENE

Protective role of miR-155 in breast cancer through RAD51 targeting impairs homologous recombination after irradiation

(2014) P. Gasparini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide analysis of the human p53 transcriptional network unveils a lncRNA tumour suppressor signature

(2014) Yolanda Sánchez et al.   Nature Communications

Exosomes: an overview of biogenesis, composition and role in ovarian cancer

(2014) Allison Beach et al.   Journal of Ovarian Research

TERRA-Reinforced Association of LSD1 with MRE11 Promotes Processing of Uncapped Telomeres

(2014) Antonio Porro et al.   Cell Reports

MicroRNAs down-regulate homologous recombination in the G1 phase of cycling cells to maintain genomic stability

(2014) Young Eun Choi et al.   eLife

MicroRNAs in the DNA Damage/Repair Network and Cancer

(2014) Alessandra Tessitore et al.   International Journal of Genomics

The Long Non-Coding RNA PCAT-1 Promotes Prostate Cancer Cell Proliferation through cMyc

(2014) John R. Prensner et al.   NEOPLASIA

Modernizing the Nonhomologous End-Joining Repertoire: Alternative and Classical NHEJ Share the Stage

(2013) Ludovic Deriano et al.   Annual Review of Genetics

MicroRNAs in Cancer

(2013) Gianpiero Di Leva et al.   Annual Review of Pathology-Mechanisms of Disease

DNA DSB repair pathway choice: an orchestrated handover mechanism

(2013) A Kakarougkas et al.   BRITISH JOURNAL OF RADIOLOGY

Oncogenic miR-181a/b affect the DNA damage response in aggressive breast cancer

(2013) Andrea BISSO et al.   CELL CYCLE

Long non-coding RNA ANRIL (CDKN2B-AS) is induced by the ATM-E2F1 signaling pathway

(2013) Guohui Wan et al.   CELLULAR SIGNALLING

Identification of miRNA modulators to PARP inhibitor response

(2013) Sari Neijenhuis et al.   DNA REPAIR

A novel non-coding RNA lncRNA-JADE connects DNA damage signalling to histone H4 acetylation

(2013) Guohui Wan et al.   EMBO JOURNAL

Non-coding RNAs in DNA damage and repair

(2013) Vivek Sharma et al.   FEBS LETTERS

Long Noncoding RNAs: Past, Present, and Future

(2013) J. T. Y. Kung et al.   GENETICS

The DNA-Damage Response to γ-Radiation Is Affected by miR-27a in A549 Cells

(2013) Andrea Di Francesco et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Detection and Repair of Ionizing Radiation-Induced DNA Double Strand Breaks: New Developments in Nonhomologous End Joining

(2013) Chen Wang et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

MALAT1 — a paradigm for long noncoding RNA function in cancer

(2013) Tony Gutschner et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

MicroRNA-124 (miR-124) Regulates Ku70 Expression and is Correlated with Neuronal Death Induced by Ischemia/Reperfusion

(2013) Fei Zhu et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Systematic Screen Identifies miRNAs That Target RAD51 and RAD51D to Enhance Chemosensitivity

(2013) J.-W. Huang et al.   MOLECULAR CANCER RESEARCH

DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities

(2013) Atsushi Shibata et al.   MOLECULAR CELL

LncRNA loc285194 is a p53-regulated tumor suppressor

(2013) Qian Liu et al.   NUCLEIC ACIDS RESEARCH

DNA double-strand-break complexity levels and their possible contributions to the probability for error-prone processing and repair pathway choice

(2013) A. Schipler et al.   NUCLEIC ACIDS RESEARCH

A direct role for small non-coding RNAs in DNA damage response

(2013) Fabrizio d’Adda di Fagagna   TRENDS IN CELL BIOLOGY

ATM–Dependent MiR-335 Targets CtIP and Modulates the DNA Damage Response

(2013) Nathan T. Martin et al.   PLoS Genetics

Multiple knockout mouse models reveal lincRNAs are required for life and brain development

(2013) Martin Sauvageau et al.   eLife

Pint lincRNA connects the p53 pathway with epigenetic silencing by the Polycomb repressive complex 2

(2013) Oskar Marín-Béjar et al.   GENOME BIOLOGY

MiR-96 Downregulates REV1 and RAD51 to Promote Cellular Sensitivity to Cisplatin and PARP Inhibition

(2012) Yemin Wang et al.   CANCER RESEARCH

A Role for Small RNAs in DNA Double-Strand Break Repair

(2012) Wei Wei et al.   CELL

The human long non-coding RNA-RoR is a p53 repressor in response to DNA damage

(2012) Ali Zhang et al.   CELL RESEARCH

A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure

(2012) Martijn S Luijsterburg et al.   EMBO JOURNAL

Regulation of DNA-End Resection by hnRNPU-like Proteins Promotes DNA Double-Strand Break Signaling and Repair

(2012) Sophie E. Polo et al.   MOLECULAR CELL

Inheritance of Silent rDNA Chromatin Is Mediated by PARP1 via Noncoding RNA

(2012) Claudio Guetg et al.   MOLECULAR CELL

Playing the End Game: DNA Double-Strand Break Repair Pathway Choice

(2012) J. Ross Chapman et al.   MOLECULAR CELL

LincRNA-p21 Suppresses Target mRNA Translation

(2012) Je-Hyun Yoon et al.   MOLECULAR CELL

Landscape of transcription in human cells

(2012) Sarah Djebali et al.   NATURE

Site-specific DICER and DROSHA RNA products control the DNA-damage response

(2012) Sofia Francia et al.   NATURE

The DNA damage response and cancer therapy

(2012) Christopher J. Lord et al.   NATURE

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

A small RNA response at DNA ends in Drosophila

(2012) Katharina M. Michalik et al.   NUCLEIC ACIDS RESEARCH

MicroRNA-182-5p targets a network of genes involved in DNA repair

(2012) K. Krishnan et al.   RNA

Secreted microRNAs: a new form of intercellular communication

(2012) Xi Chen et al.   TRENDS IN CELL BIOLOGY

V(D)J Recombination: Mechanisms of Initiation

(2011) David G. Schatz et al.   Annual Review of Genetics

Plasma microRNA 210 levels correlate with sensitivity to trastuzumab and tumor presence in breast cancer patients

(2011) Eun-Jung Jung et al.   CANCER

ncRNA- and Pc2 Methylation-Dependent Gene Relocation between Nuclear Structures Mediates Gene Activation Programs

(2011) Liuqing Yang et al.   CELL

Wrap53, a novel regulator of p53

(2011) Marianne Farnebo   CELL CYCLE

Factors determining DNA double-strand break repair pathway choice in G2 phase

(2011) Atsushi Shibata et al.   EMBO JOURNAL

Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita

(2011) F. Zhong et al.   GENES & DEVELOPMENT

Paraspeckles are subpopulation-specific nuclear bodies that are not essential in mice

(2011) Shinichi Nakagawa et al.   JOURNAL OF CELL BIOLOGY

MicroRNA-138 Modulates DNA Damage Response by Repressing Histone H2AX Expression

(2011) Y. Wang et al.   MOLECULAR CANCER RESEARCH

lncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 3′ UTRs via Alu elements

(2011) Chenguang Gong et al.   NATURE

Initial impact of the sequencing of the human genome

(2011) Eric S. Lander   NATURE

TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA

(2011) Rachel Litman Flynn et al.   NATURE

Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression

(2011) John R Prensner et al.   NATURE BIOTECHNOLOGY

Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters

(2011) Tiffany Hung et al.   NATURE GENETICS

The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway

(2010) Michael R. Lieber   Annual Review of Biochemistry

The RecQ DNA Helicases in DNA Repair

(2010) Kara A. Bernstein et al.   Annual Review of Genetics

A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

(2010) Maite Huarte et al.   CELL

Mre11–Rad50–Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaks

(2010) Gareth J. Williams et al.   DNA REPAIR

A long nuclear-retained non-coding RNA regulates synaptogenesis by modulating gene expression

(2010) Delphine Bernard et al.   EMBO JOURNAL

The NoRC complex mediates the heterochromatin formation and stability of silent rRNA genes and centromeric repeats

(2010) Claudio Guetg et al.   EMBO JOURNAL

Hereditary breast and ovarian cancer due to mutations in BRCA1 and BRCA2

(2010) Nancie Petrucelli et al.   GENETICS IN MEDICINE

The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation

(2010) Vidisha Tripathi et al.   MOLECULAR CELL

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

miR-182-Mediated Downregulation of BRCA1 Impacts DNA Repair and Sensitivity to PARP Inhibitors

(2010) Patryk Moskwa et al.   MOLECULAR CELL

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

(2010) Rajnish A. Gupta et al.   NATURE

A coding-independent function of gene and pseudogene mRNAs regulates tumour biology

(2010) Laura Poliseno et al.   NATURE

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

(2010) Mary Ellen Moynahan et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Targeting DNA-PKcs and ATM with miR-101 Sensitizes Tumors to Radiation

(2010) Dan Yan et al.   PLoS One

ATM is down-regulated by N-Myc-regulated microRNA-421

(2010) H. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ligase IV syndrome

(2009) Dimitry A. Chistiakov et al.   European Journal of Medical Genetics

Long noncoding RNAs: functional surprises from the RNA world

(2009) J. E. Wilusz et al.   GENES & DEVELOPMENT

Wrap53, a Natural p53 Antisense Transcript Required for p53 Induction upon DNA Damage

(2009) Salah Mahmoudi et al.   MOLECULAR CELL

A Conserved WD40 Protein Binds the Cajal Body Localization Signal of scaRNP Particles

(2009) Kazimierz T. Tycowski et al.   MOLECULAR CELL

An Architectural Role for a Nuclear Noncoding RNA: NEAT1 RNA Is Essential for the Structure of Paraspeckles

(2009) Christine M. Clemson et al.   MOLECULAR CELL

Altered Nuclear Retention of mRNAs Containing Inverted Repeats in Human Embryonic Stem Cells: Functional Role of a Nuclear Noncoding RNA

(2009) Ling-Ling Chen et al.   MOLECULAR CELL

FANCM Connects the Genome Instability Disorders Bloom's Syndrome and Fanconi Anemia

(2009) Andrew J. Deans et al.   MOLECULAR CELL

Crystal structure of DNA-PKcs reveals a large open-ring cradle comprised of HEAT repeats

(2009) Bancinyane L. Sibanda et al.   NATURE

qiRNA is a new type of small interfering RNA induced by DNA damage

(2009) Heng-Chi Lee et al.   NATURE

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Balanced gene regulation by an embryonic brain ncRNA is critical for adult hippocampal GABA circuitry

(2009) Allison M Bond et al.   NATURE NEUROSCIENCE

Long non-coding RNAs: insights into functions

(2009) Tim R. Mercer et al.   NATURE REVIEWS GENETICS

miR-24–mediated downregulation of H2AX suppresses DNA repair in terminally differentiated blood cells

(2009) Ashish Lal et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DNA Damage, Aging, and Cancer

(2009) Jan H.J. Hoeijmakers   NEW ENGLAND JOURNAL OF MEDICINE

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

(2009) Ahmad M. Khalil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism of Eukaryotic Homologous Recombination

(2008) Joseph San Filippo et al.   Annual Review of Biochemistry

A functional polymorphism in the miR-146a gene and age of familial breast/ovarian cancer diagnosis

(2008) Jie Shen et al.   CARCINOGENESIS

3′ End Processing of a Long Nuclear-Retained Noncoding RNA Yields a tRNA-like Cytoplasmic RNA

(2008) Jeremy E. Wilusz et al.   CELL

Transcriptional regulation of the cyclin D1 gene at a glance

(2008) E. A. Klein et al.   JOURNAL OF CELL SCIENCE

A DNA-PKcs mutation in a radiosensitive T–B– SCID patient inhibits Artemis activation and nonhomologous end-joining

(2008) Mirjam van der Burg et al.   JOURNAL OF CLINICAL INVESTIGATION

Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription

(2008) Xiangting Wang et al.   NATURE

Regulation of DNA repair throughout the cell cycle

(2008) Dana Branzei et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Alternative-NHEJ Is a Mechanistically Distinct Pathway of Mammalian Chromosome Break Repair

(2008) Nicole Bennardo et al.   PLoS Genetics