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Title
PPAR Beta/Delta and the Hallmarks of Cancer
Authors
Keywords
-
Journal
Cells
Volume 9, Issue 5, Pages 1133
Publisher
MDPI AG
Online
2020-05-05
DOI
10.3390/cells9051133
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- (2020) Yue Xi et al. Cells
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- PPARβ/δ Agonist GW501516 Inhibits Tumorigenesis and Promotes Apoptosis of the Undifferentiated Nasopharyngeal Carcinoma C666-1 Cells by Regulating miR-206
- (2019) Linglan Gu et al. ONCOLOGY RESEARCH
- Exploration and Development of PPAR Modulators in Health and Disease: An Update of Clinical Evidence
- (2019) Cheng et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Peroxisome proliferator-activated receptor agonists and antagonists: a patent review (2014-present)
- (2019) Ichiro Takada et al. EXPERT OPINION ON THERAPEUTIC PATENTS
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- (2019) Kay-Dietrich Wagner et al. Cells
- Induction of apoptosis in prostate cancer by ginsenoside Rh2
- (2018) Tony Tong-Lin Wu et al. Oncotarget
- PPARβ/δ Agonist GW501516 Inhibits Tumorigenicity of Undifferentiated Nasopharyngeal Carcinoma in C666-1 Cells by Promoting Apoptosis
- (2018) Yangyang Ji et al. Frontiers in Pharmacology
- Dual blockade of VEGFR1 and VEGFR2 by a novel peptide abrogates VEGF-driven angiogenesis, tumor growth, and metastasis through PI3K/AKT and MAPK/ERK1/2 pathway
- (2018) Afsaneh Sadremomtaz et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
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- (2018) Sun Ah Ham et al. INTERNATIONAL JOURNAL OF CANCER
- The Role of PPARβ/δ in Melanoma Metastasis
- (2018) Jonathan Lim et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2018) Yi Liu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2017) Pei-Li Yao et al. MOLECULAR CARCINOGENESIS
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- (2017) Maja Milanovic et al. NATURE
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- (2016) Tony Tong-Lin Wu et al. EUROPEAN JOURNAL OF PHARMACOLOGY
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- (2016) Semir Beyaz et al. NATURE
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- (2016) Gayathri Balandaram et al. TOXICOLOGY
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- Inducible Conditional Vascular-Specific Overexpression of Peroxisome Proliferator-Activated Receptor Beta/Delta Leads to Rapid Cardiac Hypertrophy
- (2016) Kay-Dietrich Wagner et al. PPAR Research
- PPAR-delta promotes survival of breast cancer cells in harsh metabolic conditions
- (2016) X Wang et al. Oncogenesis
- A role for Peroxisome Proliferator-Activated Receptor Beta in T cell development
- (2016) Isabelle Mothe-Satney et al. Scientific Reports
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- (2015) Fang He et al. DIGESTIVE AND LIVER DISEASE
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- (2013) Jeroen FJ Bogie et al. Acta Neuropathologica Communications
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- (2012) Livius V. d'Uscio et al. CARDIOVASCULAR RESEARCH
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- (2012) X. Y. Tian et al. DIABETES
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- (2011) D Wang et al. ONCOGENE
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