The transcriptional PPARβ/δ network in human macrophages defines a unique agonist-induced activation state

Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation

(2014) Jia Xue et al.   IMMUNITY

PPARβ/δ activation of CD300a controls intestinal immunity

(2014) Toshiya Tanaka et al.   Scientific Reports

Mixed-polarization phenotype of ascites-associated macrophages in human ovarian carcinoma: Correlation of CD163 expression, cytokine levels and early relapse

(2013) Silke Reinartz et al.   INTERNATIONAL JOURNAL OF CANCER

DIXDC1 increases the invasion and migration ability of non-small-cell lung cancer cells via the PI3K-AKT/AP-1 pathway

(2013) Zhonghai Xu et al.   MOLECULAR CARCINOGENESIS

The Subread aligner: fast, accurate and scalable read mapping by seed-and-vote

(2013) Yang Liao et al.   NUCLEIC ACIDS RESEARCH

Regulation of TAK1/TAB1-Mediated IL-1β Signaling by Cytoplasmic PPARβ/δ

(2013) Josefine Stockert et al.   PLoS One

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Genome-wide analysis of STAT3 binding in vivo predicts effectors of the anti-inflammatory response in macrophages

(2012) A. P. Hutchins et al.   BLOOD

G-actin regulates the shuttling and PP1 binding of the RPEL protein Phactr1 to control actomyosin assembly

(2012) M. Wiezlak et al.   JOURNAL OF CELL SCIENCE

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Inverse PPARβ/δ agonists suppress oncogenic signaling to the ANGPTL4 gene and inhibit cancer cell invasion

(2012) T Adhikary et al.   ONCOGENE

Skin-Targeted Inhibition of PPAR β/δ by Selective Antagonists to Treat PPAR β/δ – Mediated Psoriasis-Like Skin Disease In Vivo

(2012) Katrin Hack et al.   PLoS One

PPARs at the crossroads of lipid signaling and inflammation

(2012) Walter Wahli et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Indoleamine 2,3 dioxygenase and metabolic control of immune responses

(2012) David H. Munn et al.   TRENDS IN IMMUNOLOGY

Activation of PPARγ and δ by dietary punicic acid ameliorates intestinal inflammation in mice

(2011) Josep Bassaganya-Riera et al.   BRITISH JOURNAL OF NUTRITION

Development of Improved PPARβ/δ Inhibitors

(2011) Philipp M. Toth et al.   ChemMedChem

Activation of Peroxisome Proliferator-Activated Receptor- /-  (PPAR- /- ) Ameliorates Insulin Signaling and Reduces SOCS3 Levels by Inhibiting STAT3 in Interleukin-6-Stimulated Adipocytes

(2011) L. Serrano-Marco et al.   DIABETES

The peroxisome proliferator-activated receptor (PPAR) β/δ agonist GW501516 inhibits IL-6-induced signal transducer and activator of transcription 3 (STAT3) activation and insulin resistance in human liver cells

(2011) L. Serrano-Marco et al.   DIABETOLOGIA

Hypoxia and Inflammation

(2011) Holger K. Eltzschig et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genomewide Analyses Define Different Modes of Transcriptional Regulation by Peroxisome Proliferator-Activated Receptor-β/δ (PPARβ/δ)

(2011) Till Adhikary et al.   PLoS One

Bcl-6 and NF- B cistromes mediate opposing regulation of the innate immune response

(2010) G. D. Barish et al.   GENES & DEVELOPMENT

Identification and Characterization of Enhancers Controlling the Inflammatory Gene Expression Program in Macrophages

(2010) Serena Ghisletti et al.   IMMUNITY

The PD-1 pathway in tolerance and autoimmunity

(2010) Loise M. Francisco et al.   IMMUNOLOGICAL REVIEWS

Peroxisome proliferator-activated receptor δ agonists inhibit T helper type 1 (Th1) and Th17 responses in experimental allergic encephalomyelitis

(2010) Saravanan Kanakasabai et al.   IMMUNOLOGY

Dixdc1 Is a Critical Regulator of DISC1 and Embryonic Cortical Development

(2010) Karun K. Singh et al.   NEURON

Reverse crosstalk of TGFβ and PPARβ/δ signaling identified by transcriptional profiling

(2010) Josefine Stockert et al.   NUCLEIC ACIDS RESEARCH

Activation of PPARβ/δ Causes a Psoriasis-Like Skin Disease In Vivo

(2010) Malgorzata Romanowska et al.   PLoS One

Regulation of Immune Responses and Autoimmune Encephalomyelitis by PPARs

(2010) Yuhong Yang et al.   PPAR Research

Regulation of epithelial–mesenchymal IL-1 signaling by PPARβ/δ is essential for skin homeostasis and wound healing

(2009) Han Chung Chong et al.   JOURNAL OF CELL BIOLOGY

15-Hydroxyeicosatetraenoic Acid Is a Preferential Peroxisome Proliferator-Activated Receptor  /  Agonist

(2009) S. Naruhn et al.   MOLECULAR PHARMACOLOGY

Structural and Functional Aspects of Lipid Binding by CD1 Molecules

(2008) Jonathan D. Silk et al.   Annual Review of Cell and Developmental Biology

Adipocyte-Derived Th2 Cytokines and Myeloid PPARδ Regulate Macrophage Polarization and Insulin Sensitivity

(2008) Kihwa Kang et al.   Cell Metabolism

Alternative M2 Activation of Kupffer Cells by PPARδ Ameliorates Obesity-Induced Insulin Resistance

(2008) Justin I. Odegaard et al.   Cell Metabolism

Activation of Peroxisome Proliferator-Activated Receptor  /  Inhibits Lipopolysaccharide-Induced Cytokine Production in Adipocytes by Lowering Nuclear Factor- B Activity via Extracellular Signal-Related Kinase 1/2

(2008) R. Rodriguez-Calvo et al.   DIABETES

PPAR-β/δ agonists for Type 2 diabetes and dyslipidemia: an adopted orphan still looking for a home

(2008) Andrew N Billin   EXPERT OPINION ON INVESTIGATIONAL DRUGS

PPARs Mediate Lipid Signaling in Inflammation and Cancer

(2008) Liliane Michalik et al.   PPAR Research

Identification and Characterization of a Selective Peroxisome Proliferator-Activated Receptor β/δ (NR1C2) Antagonist

(2007) Barry G. Shearer et al.   MOLECULAR ENDOCRINOLOGY