15-Lipoxygenase-1 suppression of colitis-associated colon cancer through inhibition of the IL-6/STAT3 signaling pathway

NOTCH3 Signaling Regulates MUSASHI-1 Expression in Metastatic Colorectal Cancer Cells

(2014) A. Pasto et al.   CANCER RESEARCH

Potentiation of Colon Cancer Susceptibility in Mice by Colonic Epithelial PPAR-δ/β Overexpression

(2014) Xiangsheng Zuo et al.   JNCI-Journal of the National Cancer Institute

Peroxisome proliferator-activated receptor   promotes colonic inflammation and tumor growth

(2014) D. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

15-Lipoxygenases in cancer: A double-edged sword?

(2013) Adi J. Klil-Drori et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Sphingosine-1-Phosphate Links Persistent STAT3 Activation, Chronic Intestinal Inflammation, and Development of Colitis-Associated Cancer

(2012) Jie Liang et al.   CANCER CELL

Prohibitin Attenuates Colitis-Associated Tumorigenesis in Mice by Modulating p53 and STAT3 Apoptotic Responses

(2012) A. S. Kathiria et al.   CANCER RESEARCH

Effects of Gut-Targeted 15-LOX-1 Transgene Expression on Colonic Tumorigenesis in Mice

(2012) Xiangsheng Zuo et al.   JNCI-Journal of the National Cancer Institute

The Unholy Trinity: Inflammation, Cytokines, and STAT3 Shape The Cancer Microenvironment

(2011) Ning Li et al.   CANCER CELL

Mechanistic Contribution of Ubiquitous 15-Lipoxygenase-1 Expression Loss in Cancer Cells to Terminal Cell Differentiation Evasion

(2011) M. J. Moussalli et al.   Cancer Prevention Research

IL-6 signaling in autoimmunity, chronic inflammation and inflammation-associated cancer

(2011) Markus F. Neurath et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in mice

(2011) Immanuel Lerner et al.   JOURNAL OF CLINICAL INVESTIGATION

Notch3 signalling promotes tumour growth in colorectal cancer

(2011) Valentina Serafin et al.   JOURNAL OF PATHOLOGY

MUC1-C Oncoprotein Promotes STAT3 Activation in an Autoinductive Regulatory Loop

(2011) R. Ahmad et al.   Science Signaling

Profiling Lipoxygenase Metabolism in Specific Steps of Colorectal Tumorigenesis

(2010) I. Shureiqi et al.   Cancer Prevention Research

Cellular and Pharmacological Selectivity of the Peroxisome Proliferator-Activated Receptor- /  Antagonist GSK3787

(2010) P. S. Palkar et al.   MOLECULAR PHARMACOLOGY

gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis

(2009) Julia Bollrath et al.   CANCER CELL

IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

(2009) Sergei Grivennikov et al.   CANCER CELL

Dangerous liaisons: STAT3 and NF-κB collaboration and crosstalk in cancer

(2009) Sergei I. Grivennikov et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Disease-related expression of the IL6/STAT3/SOCS3 signalling pathway in ulcerative colitis and ulcerative colitis-related carcinogenesis

(2009) Y. Li et al.   GUT

Serum interleukin-6 levels in colorectal cancer patients—a summary of published results

(2009) Heike Knüpfer et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

Essential Roles of IL-6 Trans-Signaling in Colonic Epithelial Cells, Induced by the IL-6/Soluble-IL-6 Receptor Derived from Lamina Propria Macrophages, on the Development of Colitis-Associated Premalignant Cancer in a Murine Model

(2009) S. Matsumoto et al.   JOURNAL OF IMMUNOLOGY

Targeted Genetic Disruption of Peroxisome Proliferator–Activated Receptor-δ and Colonic Tumorigenesis

(2009) Xiangsheng Zuo et al.   JNCI-Journal of the National Cancer Institute

Endoscopic and pathological aspects of colitis-associated dysplasia

(2009) Fiona D. M. van Schaik et al.   Nature Reviews Gastroenterology & Hepatology

Direct Health Care Costs of Crohn's Disease and Ulcerative Colitis in US Children and Adults

(2008) Michael D. Kappelman et al.   GASTROENTEROLOGY

The wolf in sheep's clothing: the role of interleukin-6 in immunity, inflammation and cancer

(2008) Willscott E. Naugler et al.   TRENDS IN MOLECULAR MEDICINE