A Review of Scientific Evidence for THC:CBD Oromucosal Spray (Nabiximols) in the Management of Chronic Pain
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Title
A Review of Scientific Evidence for THC:CBD Oromucosal Spray (Nabiximols) in the Management of Chronic Pain
Authors
Keywords
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Journal
Journal of Pain Research
Volume Volume 13, Issue -, Pages 399-410
Publisher
Informa UK Limited
Online
2020-02-14
DOI
10.2147/jpr.s240011
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Related references
Note: Only part of the references are listed.- Real-world incidence and prevalence of low back pain using routinely collected data
- (2019) Francis Fatoye et al. RHEUMATOLOGY INTERNATIONAL
- Opioid use disorder in chronic non-cancer pain in Germany: a cross sectional study
- (2019) Johannes Maximilian Just et al. BMJ Open
- Effectiveness and tolerability of THC:CBD oromucosal spray as add-on measure in patients with severe chronic pain: analysis of 12-week open-label real-world data provided by the German Pain e-Registry
- (2019) Michael Ueberall et al. Journal of Pain Research
- Cancer Pain Assessment and Classification
- (2019) Augusto Caraceni et al. Cancers
- Trends in use and misuse of opioids in the Netherlands: a retrospective, multi-source database study
- (2019) Gerard Arnoldus Kalkman et al. Lancet Public Health
- An Analysis of the Neuropathic Pain Components in Rheumatoid Arthritis Patients
- (2018) Satoshi Ito et al. INTERNAL MEDICINE
- Sativex® as Add-on therapy Vs. further optimized first-line ANTispastics (SAVANT) in resistant multiple sclerosis spasticity: a double-blind, placebo-controlled randomised clinical trial
- (2018) Jolana Markovà et al. INTERNATIONAL JOURNAL OF NEUROSCIENCE
- Results of a Double-Blind, Randomized, Placebo-Controlled Study of Nabiximols Oromucosal Spray as an Adjunctive Therapy in Advanced Cancer Patients with Chronic Uncontrolled Pain
- (2018) Aron H. Lichtman et al. JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
- The Transient Receptor Potential Ankyrin Type 1 Plays a Critical Role in Cortical Spreading Depression
- (2018) Liwen Jiang et al. NEUROSCIENCE
- European Pain Federation (EFIC) position paper on appropriate use of cannabis-based medicines and medical cannabis for chronic pain management
- (2018) Winfried Häuser et al. EUROPEAN JOURNAL OF PAIN
- Cannabidiol modulates serotonergic transmission and prevents allodynia and anxiety-like behavior in a model of neuropathic pain
- (2018) Danilo De Gregorio et al. PAIN
- Cannabinoids and Pain: New Insights From Old Molecules
- (2018) Sonja Vučković et al. Frontiers in Pharmacology
- Cannabinoids therapeutic use: what is our current understanding following the introduction of THC, THC:CBD oromucosal spray and others?
- (2017) Mauro Maccarrone et al. Expert Review of Clinical Pharmacology
- Neuropathic pain
- (2017) Luana Colloca et al. Nature Reviews Disease Primers
- Chronic Pain: How Challenging Are DDIs in the Analgesic Treatment of Inpatients with Multiple Chronic Conditions?
- (2017) Klarissa Siebenhuener et al. PLoS One
- The painDETECT project – far more than a screening tool on neuropathic pain
- (2016) Rainer Freynhagen et al. CURRENT MEDICAL RESEARCH AND OPINION
- European Pain Federation position paper on appropriate opioid use in chronic pain management
- (2016) T. O'Brien et al. EUROPEAN JOURNAL OF PAIN
- Transient Receptor Potential Melastatin 8 Channel (TRPM8) Modulation: Cool Entryway for Treating Pain and Cancer
- (2016) M. Jesús Pérez de Vega et al. JOURNAL OF MEDICINAL CHEMISTRY
- Efficacy and safety of cannabinoid oromucosal spray for multiple sclerosis spasticity
- (2016) F Patti et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Pharmacological management of spasticity in multiple sclerosis: Systematic review and consensus paper
- (2016) Susana Otero-Romero et al. Multiple Sclerosis Journal
- Reducing the Risks of Relief — The CDC Opioid-Prescribing Guideline
- (2016) Thomas R. Frieden et al. NEW ENGLAND JOURNAL OF MEDICINE
- Equilibrative nucleoside transporters—A review
- (2016) Rebba C. Boswell-Casteel et al. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
- The endocannabinoid system and neuropathic pain
- (2016) Rafael Maldonado et al. PAIN
- Evaluating Sativex®in Neuropathic Pain Management: A Clinical and Neurophysiological Assessment in Multiple Sclerosis
- (2016) Margherita Russo et al. PAIN MEDICINE
- An overview of treatment approaches for chronic pain management
- (2016) Nicholas Hylands-White et al. RHEUMATOLOGY INTERNATIONAL
- Prevalence of chronic pain in the UK: a systematic review and meta-analysis of population studies
- (2016) A Fayaz et al. BMJ Open
- Pharmacological management of spasticity in multiple sclerosis: Systematic review and consensus paper
- (2016) Susana Otero-Romero et al. Multiple Sclerosis Journal
- Are cannabidiol and Δ9-tetrahydrocannabivarin negative modulators of the endocannabinoid system? A systematic review
- (2015) John M McPartland et al. BRITISH JOURNAL OF PHARMACOLOGY
- Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor
- (2015) R B Laprairie et al. BRITISH JOURNAL OF PHARMACOLOGY
- Endocannabinoid signalling and the deteriorating brain
- (2015) Vincenzo Di Marzo et al. NATURE REVIEWS NEUROSCIENCE
- Molecular Targets of Cannabidiol in Neurological Disorders
- (2015) Clementino Ibeas Bih et al. Neurotherapeutics
- A classification of chronic pain for ICD-11
- (2015) Rolf-Detlef Treede et al. PAIN
- Endocannabinoid signaling at the periphery: 50 years after THC
- (2015) Mauro Maccarrone et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders
- (2014) Orrin Devinsky et al. EPILEPSIA
- A double-blind, randomized, placebo-controlled, parallel group study of THC/CBD spray in peripheral neuropathic pain treatment
- (2014) M. Serpell et al. EUROPEAN JOURNAL OF PAIN
- Nabiximols (THC/CBD Oromucosal Spray, Sativex®) in Clinical Practice - Results of a Multicenter, Non-Interventional Study (MOVE 2) in Patients with Multiple Sclerosis Spasticity
- (2014) Peter Flachenecker et al. EUROPEAN NEUROLOGY
- A multicentre, open-label, follow-on study to assess the long-term maintenance of effect, tolerance and safety of THC/CBD oromucosal spray in the management of neuropathic pain
- (2014) B. Hoggart et al. JOURNAL OF NEUROLOGY
- Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies
- (2014) Mauro Maccarrone et al. NATURE REVIEWS NEUROSCIENCE
- The individual and societal burden of chronic pain in Europe: the case for strategic prioritisation and action to improve knowledge and availability of appropriate care
- (2013) Harald Breivik et al. BMC PUBLIC HEALTH
- A review of the cultivation and processing of cannabis (Cannabis sativaL.) for production of prescription medicines in the UK
- (2013) David J. Potter Drug Testing and Analysis
- A Double-Blind, Placebo-Controlled, Crossover Pilot Trial With Extension Using an Oral Mucosal Cannabinoid Extract for Treatment of Chemotherapy-Induced Neuropathic Pain
- (2013) Mary E. Lynch et al. JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
- P5-HT1A receptors in mood and anxiety: recent insights into autoreceptor versus heteroreceptor function
- (2013) Alvaro L. Garcia-Garcia et al. PSYCHOPHARMACOLOGY
- Synaptic Targets of 9-Tetrahydrocannabinol in the Central Nervous System
- (2013) A. F. Hoffman et al. Cold Spring Harbor Perspectives in Medicine
- Orphan G protein receptor GPR55 as an emerging target in cancer therapy and management
- (2013) Sharon DeMorrow et al. Cancer Management and Research
- A double-blind, randomized, placebo-controlled, parallel-group study of THC/CBD oromucosal spray in combination with the existing treatment regimen, in the relief of central neuropathic pain in patients with multiple sclerosis
- (2012) R. M. Langford et al. JOURNAL OF NEUROLOGY
- Nabiximols for Opioid-Treated Cancer Patients With Poorly-Controlled Chronic Pain: A Randomized, Placebo-Controlled, Graded-Dose Trial
- (2012) Russell K. Portenoy et al. JOURNAL OF PAIN
- The Economic Costs of Pain in the United States
- (2012) Darrell J. Gaskin et al. JOURNAL OF PAIN
- An Open-Label Extension Study to Investigate the Long-Term Safety and Tolerability of THC/CBD Oromucosal Spray and Oromucosal THC Spray in Patients With Terminal Cancer-Related Pain Refractory to Strong Opioid Analgesics
- (2012) Jeremy R. Johnson et al. JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
- The burden associated with neuropathic pain in Western Europe
- (2012) Paul C. Langley et al. JOURNAL OF MEDICAL ECONOMICS
- European survey of chronic pain patients: results for Germany
- (2011) G.H.H. Müller-Schwefe CURRENT MEDICAL RESEARCH AND OPINION
- The prevalence, correlates and treatment of pain in the European Union
- (2011) P.C. Langley CURRENT MEDICAL RESEARCH AND OPINION
- A randomized, double-blind, placebo-controlled, parallel-group, enriched-design study of nabiximols* (Sativex®), as add-on therapy, in subjects with refractory spasticity caused by multiple sclerosis
- (2011) A. Novotna et al. EUROPEAN JOURNAL OF NEUROLOGY
- Sativex®(tetrahydrocannabinol + cannabidiol), an endocannabinoid system modulator: basic features and main clinical data
- (2011) Patrick Vermersch Expert Review of Neurotherapeutics
- A placebo-controlled, parallel-group, randomized withdrawal study of subjects with symptoms of spasticity due to multiple sclerosis who are receiving long-term Sativex® (nabiximols)
- (2011) W Notcutt et al. Multiple Sclerosis Journal
- The specific disease burden of neuropathic pain: Results of a French nationwide survey
- (2011) Nadine Attal et al. PAIN
- The prevalence, correlates and treatment of pain in Spain
- (2011) Paul C. Langley et al. JOURNAL OF MEDICAL ECONOMICS
- Role of Cannabinoids in the Treatment of Pain and (Painful) Spasticity
- (2010) Matthias Karst et al. DRUGS
- EFNS guidelines on the pharmacological treatment of neuropathic pain: 2010 revision
- (2010) N. Attal et al. EUROPEAN JOURNAL OF NEUROLOGY
- A double-blind, randomized, placebo-controlled, parallel-group study of Sativex, in subjects with symptoms of spasticity due to multiple sclerosis
- (2010) C. Collin et al. NEUROLOGICAL RESEARCH
- Multicenter, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Study of the Efficacy, Safety, and Tolerability of THC:CBD Extract and THC Extract in Patients with Intractable Cancer-Related Pain
- (2009) Jeremy R. Johnson et al. JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
- Cannabinoid modulation of hippocampal long-term memory is mediated by mTOR signaling
- (2009) Emma Puighermanal et al. NATURE NEUROSCIENCE
- The Prevalence and Impact of Chronic Pain with Neuropathic Pain Symptoms in the General Population
- (2009) Cory Toth et al. PAIN MEDICINE
- Neuropathic Pain
- (2009) Alec B. OʼConnor PHARMACOECONOMICS
- POSTER SESSION 2, MONDAY 25 AUGUST
- (2008) EUROPEAN JOURNAL OF NEUROLOGY
- Cannabis use and risk of lung cancer: a case-control study
- (2008) S. Aldington et al. EUROPEAN RESPIRATORY JOURNAL
- Potency of Δ9–THC and Other Cannabinoids in Cannabis in England in 2005: Implications for Psychoactivity and Pharmacology
- (2008) David J. Potter et al. JOURNAL OF FORENSIC SCIENCES
- Cannabinoid Receptors: Where They are and What They do
- (2008) K. Mackie JOURNAL OF NEUROENDOCRINOLOGY
- The diverse CB1and CB2receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin
- (2007) R G Pertwee BRITISH JOURNAL OF PHARMACOLOGY
- Prevalence of chronic pain with neuropathic characteristics in the general population
- (2007) Didier Bouhassira et al. PAIN
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