P5-HT1A receptors in mood and anxiety: recent insights into autoreceptor versus heteroreceptor function

Serotonin 5-HT1A Receptors as Targets for Agents to Treat Psychiatric Disorders: Rationale and Current Status of Research

(2013) Pau Celada et al.   CNS DRUGS

50 years of hurdles and hope in anxiolytic drug discovery

(2013) Guy Griebel et al.   NATURE REVIEWS DRUG DISCOVERY

Insights into the complex influence of 5-HT signaling on thalamocortical axonal system development

(2012) Esmee S. B. van Kleef et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Increased Serotonin-1A (5-HT1A) Autoreceptor Expression and Reduced Raphe Serotonin Levels in Deformed Epidermal Autoregulatory Factor-1 (Deaf-1) Gene Knock-out Mice

(2012) Margaret Czesak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biased agonism at serotonin 5-HT1A receptors: preferential postsynaptic activity for improved therapy of CNS disorders

(2012) Adrian Newman-Tancredi   Neuropsychiatry

Projections and interconnections of genetically defined serotonin neurons in mice

(2011) Sun Jung Bang et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Cost of disorders of the brain in Europe 2010

(2011) Anders Gustavsson et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Serotonin-1A Autoreceptors Are Necessary and Sufficient for the Normal Formation of Circuits Underlying Innate Anxiety

(2011) J. W. Richardson-Jones et al.   JOURNAL OF NEUROSCIENCE

Modeling treatment-resistant depression

(2011) Benjamin Adam Samuels et al.   NEUROPHARMACOLOGY

Polymorphic variation at the serotonin 1-A receptor gene is associated with comorbid depression and generalized anxiety

(2011) Esther Molina et al.   PSYCHIATRIC GENETICS

Cortical GABA, Striatal Dopamine and Midbrain Serotonin as the Key Players in Compulsive and Anxiety Disorders - Results from In Vivo Imaging Studies

(2011) Susanne Nikolaus et al.   REVIEWS IN THE NEUROSCIENCES

Genetic Models of Serotonin (5-HT) Depletion: What do They Tell Us About the Developmental Role of 5-HT?

(2010) Sara Trowbridge et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Higher Serotonin 1A Binding in a Second Major Depression Cohort: Modeling and Reference Region Considerations

(2010) Ramin V. Parsey et al.   BIOLOGICAL PSYCHIATRY

Serotonin triggers a transient epigenetic mechanism that reinstates adult visual cortex plasticity in rats

(2010) José Fernando Maya Vetencourt et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

F15599, a preferential post-synaptic 5-HT1A receptor agonist: Activity in models of cognition in comparison with reference 5-HT1A receptor agonists

(2010) Ronan Depoortère et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

F15599, a highly selective post-synaptic 5-HT1A receptor agonist: in-vivo profile in behavioural models of antidepressant and serotonergic activity

(2010) Marie-Bernadette Assié et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Can We Really Accelerate and Enhance the Selective Serotonin Reuptake Inhibitor Antidepressant Effect?

(2010) Maria J. Portella et al.   JOURNAL OF CLINICAL PSYCHIATRY

The Pharmacologic Treatment of Anxiety Disorders

(2010) Lakshmi N. Ravindran et al.   JOURNAL OF CLINICAL PSYCHIATRY

Neuronal Nitric Oxide Synthase Alteration Accounts for the Role of 5-HT1A Receptor in Modulating Anxiety-Related Behaviors

(2010) J. Zhang et al.   JOURNAL OF NEUROSCIENCE

Serotonin Receptor Imaging: Clinically Useful?

(2010) R. V. Parsey   JOURNAL OF NUCLEAR MEDICINE

5-HT1A Autoreceptor Levels Determine Vulnerability to Stress and Response to Antidepressants

(2010) Jesse W. Richardson-Jones et al.   NEURON

Association Study between 5-HT1A Receptor Gene C(-1019)G Polymorphism and Panic Disorder in a Korean Population

(2010) Won-Seok Choi et al.   Psychiatry Investigation

Effects of HTR1A C(−1019)G on Amygdala Reactivity and Trait Anxiety

(2009) Eric Fakra et al.   ARCHIVES OF GENERAL PSYCHIATRY

The Serotonin-1A Receptor in Anxiety Disorders

(2009) Elena Akimova et al.   BIOLOGICAL PSYCHIATRY

Signal transduction and functional selectivity of F15599, a preferential post-synaptic 5-HT1Areceptor agonist

(2009) A Newman-Tancredi et al.   BRITISH JOURNAL OF PHARMACOLOGY

Neurobiological mechanisms in major depressive disorder

(2009) M. aan het Rot et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Sustained Neurobehavioral Effects of Exposure to SSRI Antidepressants During Development: Molecular to Clinical Evidence

(2009) T F Oberlander et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Aberrant extracellular signal-regulated kinase (ERK)1/2 signalling in suicide brain: role of ERK kinase 1 (MEK1)

(2009) Yogesh Dwivedi et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Layer II/III of the Prefrontal Cortex: Inhibition by the Serotonin 5-HT1A Receptor in Development and Stress

(2009) N. M. Goodfellow et al.   JOURNAL OF NEUROSCIENCE

From synapse to nucleus: Novel targets for treating depression

(2009) Herbert E. Covington et al.   NEUROPHARMACOLOGY

Glutamate-based antidepressants: 20 years on

(2009) Phil Skolnick et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

A role for the extracellular signal-regulated kinase signal pathway in depressive-like behavior

(2008) Xiaoli Qi et al.   BEHAVIOURAL BRAIN RESEARCH

Serotonin 5-HT1A receptor binding in people with panic disorder: positron emission tomography study

(2008) Jon R. Nash et al.   BRITISH JOURNAL OF PSYCHIATRY

5-HT1A Receptor, an Old Target for New Therapeutic Agents

(2008) Enza Lacivita et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

 -Ca2+/Calmodulin-Dependent Protein Kinase II Contributes to the Developmental Programming of Anxiety in Serotonin Receptor 1A Knock-Out Mice

(2008) L. Lo Iacono et al.   JOURNAL OF NEUROSCIENCE

Inhibition of Serotonin But Not Norepinephrine Transport during Development Produces Delayed, Persistent Perturbations of Emotional Behaviors in Mice

(2008) M. S. Ansorge et al.   JOURNAL OF NEUROSCIENCE

HES1 regulates 5-HT1A receptor gene transcription at a functional polymorphism: Essential role in developmental expression

(2008) Kirsten X. Jacobsen et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Evidence for HTR1A and LHPP as interacting genetic risk factors in major depression

(2008) C D Neff et al.   MOLECULAR PSYCHIATRY

Fluoxetine increases the activity of the ERK-CREB signal system and alleviates the depressive-like behavior in rats exposed to chronic forced swim stress

(2008) Xiaoli Qi et al.   NEUROBIOLOGY OF DISEASE

Transcriptional regulation at a HTR1A polymorphism associated with mental illness

(2008) Brice Le François et al.   NEUROPHARMACOLOGY

A study in male and female 5-HT transporter knockout rats: An animal model for anxiety and depression disorders

(2008) J.D.A. Olivier et al.   NEUROSCIENCE

The Antidepressant Fluoxetine Restores Plasticity in the Adult Visual Cortex

(2008) J. F. M. Vetencourt et al.   SCIENCE

Association study between the serotonin 1A receptor (HTR1A) gene and neuroticism, major depression, and anxiety disorders

(2007) J.M. Hettema et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Serotonin-1A autoreceptor binding in the dorsal raphe nucleus of depressed suicides

(2007) Maura Boldrini et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Altered Serotonin and Dopamine Metabolism in the CNS of Serotonin 5-HT1A or 5-HT1B Receptor Knockout Mice

(2003) Ariel R. Ase et al.   JOURNAL OF NEUROCHEMISTRY