Are cannabidiol and Δ9-tetrahydrocannabivarin negative modulators of the endocannabinoid system? A systematic review
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Title
Are cannabidiol and Δ9-tetrahydrocannabivarin negative modulators of the endocannabinoid system? A systematic review
Authors
Keywords
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Journal
BRITISH JOURNAL OF PHARMACOLOGY
Volume 172, Issue 3, Pages 737-753
Publisher
Wiley
Online
2014-09-26
DOI
10.1111/bph.12944
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Note: Only part of the references are listed.- Evaluation of the potential of the phytocannabinoids, cannabidivarin (CBDV) and Δ9-tetrahydrocannabivarin (THCV), to produce CB1receptor inverse agonism symptoms of nausea in rats
- (2013) Erin M Rock et al. BRITISH JOURNAL OF PHARMACOLOGY
- The Concise Guide to PHARMACOLOGY 2013/14: Nuclear Hormone Receptors
- (2013) Stephen P.H. Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- The Concise Guide to PHARMACOLOGY 2013/14: Ligand-Gated Ion Channels
- (2013) Stephen P.H. Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- The Concise Guide to PHARMACOLOGY 2013/14: Transporters
- (2013) Stephen P.H. Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- The Concise Guide to PHARMACOLOGY 2013/14: Enzymes
- (2013) Stephen P.H. Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- The Concise Guide to PHARMACOLOGY 2013/14: Ion Channels
- (2013) Stephen P.H. Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- The Concise Guide to PHARMACOLOGY 2013/14: G Protein-Coupled Receptors
- (2013) Stephen P.H. Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system
- (2013) Alline C. Campos et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands
- (2013) Adam J. Pawson et al. NUCLEIC ACIDS RESEARCH
- Cannabidiol attenuates catalepsy induced by distinct pharmacological mechanisms via 5-HT1A receptor activation in mice
- (2013) Felipe V. Gomes et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- The cannabinoid Δ9-tetrahydrocannabivarin (THCV) ameliorates insulin sensitivity in two mouse models of obesity
- (2013) E T Wargent et al. Nutrition & Diabetes
- A phase I study to assess the single and multiple dose pharmacokinetics of THC/CBD oromucosal spray
- (2012) C. G. Stott et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- Cannabidiol inhibits THC-elicited paranoid symptoms and hippocampal-dependent memory impairment
- (2012) Amir Englund et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Effect of chronic exposure to rimonabant and phytocannabinoids on anxiety-like behavior and saccharin palatability
- (2012) Lesley D. O'Brien et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Involvement of serotonin-mediated neurotransmission in the dorsal periaqueductal gray matter on cannabidiol chronic effects in panic-like responses in rats
- (2012) Alline Cristina Campos et al. PSYCHOPHARMACOLOGY
- Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures
- (2012) Nicholas A. Jones et al. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
- Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia
- (2012) F M Leweke et al. Translational Psychiatry
- Symptom-relieving and neuroprotective effects of the phytocannabinoid Δ9-THCV in animal models of Parkinson's disease
- (2011) C García et al. BRITISH JOURNAL OF PHARMACOLOGY
- Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects
- (2011) Ethan B Russo BRITISH JOURNAL OF PHARMACOLOGY
- Subjective and Physiological Effects After Controlled Sativex and Oral THC Administration
- (2011) E L Karschner et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Neuroprotective effects of phytocannabinoid-based medicines in experimental models of Huntington's disease
- (2011) Onintza Sagredo et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Cannabinoid potentiation of glycine receptors contributes to cannabis-induced analgesia
- (2011) Wei Xiong et al. Nature Chemical Biology
- Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Δ9-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive–compulsive behaviour
- (2011) Serena Deiana et al. PSYCHOPHARMACOLOGY
- Cannabidiol potentiates Δ9-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats
- (2011) Charlotte Klein et al. PSYCHOPHARMACOLOGY
- Cannabis with high cannabidiol content is associated with fewer psychotic experiences
- (2011) Christian D. Schubart et al. SCHIZOPHRENIA RESEARCH
- The effects of Δ9-tetrahydrocannabinol and cannabidiol alone and in combination on damage, inflammation andin vitromotility disturbances in rat colitis
- (2010) JM Jamontt et al. BRITISH JOURNAL OF PHARMACOLOGY
- The plant cannabinoid Δ9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice
- (2010) Daniele Bolognini et al. BRITISH JOURNAL OF PHARMACOLOGY
- Non-psychoactive cannabinoids modulate the descending pathway of antinociception in anaesthetized rats through several mechanisms of action
- (2010) Sabatino Maione et al. BRITISH JOURNAL OF PHARMACOLOGY
- Effects of cannabinoids and cannabinoid-enrichedCannabisextracts on TRP channels and endocannabinoid metabolic enzymes
- (2010) Luciano De Petrocellis et al. BRITISH JOURNAL OF PHARMACOLOGY
- Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic study
- (2010) Celia J. A. Morgan et al. BRITISH JOURNAL OF PSYCHIATRY
- Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis
- (2010) Susanne A Wolf et al. Cell Communication and Signaling
- Plasma Cannabinoid Pharmacokinetics following Controlled Oral 9-Tetrahydrocannabinol and Oromucosal Cannabis Extract Administration
- (2010) E. L. Karschner et al. CLINICAL CHEMISTRY
- Δ9-Tetrahydrocannabivarin suppresses in vitro epileptiform and in vivo seizure activity in adult rats
- (2010) Andrew J. Hill et al. EPILEPSIA
- Pre-synaptic adenosine A2A receptors control cannabinoid CB1 receptor-mediated inhibition of striatal glutamatergic neurotransmission
- (2010) Alberto Martire et al. JOURNAL OF NEUROCHEMISTRY
- Endocannabinoid Signaling Mediates Psychomotor Activation by Adenosine A2A Antagonists
- (2010) T. N. Lerner et al. JOURNAL OF NEUROSCIENCE
- Cannabidiol Enhances the Inhibitory Effects of 9-Tetrahydrocannabinol on Human Glioblastoma Cell Proliferation and Survival
- (2010) J. P. Marcu et al. MOLECULAR CANCER THERAPEUTICS
- Anandamide serves two masters in the brain
- (2010) Vincenzo Di Marzo NATURE NEUROSCIENCE
- Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism
- (2010) Jason R Clapper et al. NATURE NEUROSCIENCE
- Cannabidiol Attenuates the Appetitive Effects of Δ9-Tetrahydrocannabinol in Humans Smoking Their Chosen Cannabis
- (2010) Celia JA Morgan et al. NEUROPSYCHOPHARMACOLOGY
- International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2
- (2010) R. G. Pertwee et al. PHARMACOLOGICAL REVIEWS
- The endocannabinoid system, eating behavior and energy homeostasis: The end or a new beginning?
- (2010) F.J. Bermudez-Silva et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- The anxiolytic-like effects of cannabidiol injected into the bed nucleus of the stria terminalis are mediated by 5-HT1A receptors
- (2010) Felipe V. Gomes et al. PSYCHOPHARMACOLOGY
- Distinct Effects of Δ9-Tetrahydrocannabinol and Cannabidiol on Neural Activation During Emotional Processing
- (2009) Paolo Fusar-Poli et al. ARCHIVES OF GENERAL PSYCHIATRY
- Synthetic and plant-derived cannabinoid receptor antagonists show hypophagic properties in fasted and non-fasted mice
- (2009) Gernot Riedel et al. BRITISH JOURNAL OF PHARMACOLOGY
- Evaluation of prevalent phytocannabinoids in the acetic acid model of visceral nociception
- (2009) Lamont Booker et al. DRUG AND ALCOHOL DEPENDENCE
- Psychomotor performance in relation to acute oral administration of Δ9-tetrahydrocannabinol and standardized cannabis extract in healthy human subjects
- (2009) Patrik Roser et al. EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
- A behavioural comparison of acute and chronic Δ9-tetrahydrocannabinol and cannabidiol in C57BL/6JArc mice
- (2009) Leonora E. Long et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Cannabinoids Δ9-Tetrahydrocannabinol and Cannabidiol Differentially Inhibit the Lipopolysaccharide-activated NF-κB and Interferon-β/STAT Proinflammatory Pathways in BV-2 Microglial Cells
- (2009) Ewa Kozela et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Multicenter, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Study of the Efficacy, Safety, and Tolerability of THC:CBD Extract and THC Extract in Patients with Intractable Cancer-Related Pain
- (2009) Jeremy R. Johnson et al. JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
- The neuroprotective effect of cannabidiol in an in vitro model of newborn hypoxic–ischemic brain damage in mice is mediated by CB2 and adenosine receptors
- (2009) A. Castillo et al. NEUROBIOLOGY OF DISEASE
- Opposite Effects of Δ-9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology
- (2009) Sagnik Bhattacharyya et al. NEUROPSYCHOPHARMACOLOGY
- Cannabidiol reverses the reduction in social interaction produced by low dose Δ9-tetrahydrocannabinol in rats
- (2009) Daniel Thomas Malone et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Evidence for a potential role for TRPV1 receptors in the dorsolateral periaqueductal gray in the attenuation of the anxiolytic effects of cannabinoids
- (2009) Alline Cristina Campos et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb
- (2009) Angelo A. Izzo et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration
- (2009) Alessandro Liberati et al. PLOS MEDICINE
- Effects of cannabidiol on schizophrenia-like symptoms in people who use cannabis
- (2008) Celia J. A. Morgan et al. BRITISH JOURNAL OF PSYCHIATRY
- Divergent effects of cannabidiol on the discriminative stimulus and place conditioning effects of Δ9-tetrahydrocannabinol
- (2008) Robert E. Vann et al. DRUG AND ALCOHOL DEPENDENCE
- TRPV2 Is Activated by Cannabidiol and Mediates CGRP Release in Cultured Rat Dorsal Root Ganglion Neurons
- (2008) N. Qin et al. JOURNAL OF NEUROSCIENCE
- Pharmacological and therapeutic secrets of plant and brain (endo)cannabinoids
- (2008) Lumír Ondřej Hanuš MEDICINAL RESEARCH REVIEWS
- Network pharmacology: the next paradigm in drug discovery
- (2008) Andrew L Hopkins Nature Chemical Biology
- Targeting the endocannabinoid system: to enhance or reduce?
- (2008) Vincenzo Di Marzo NATURE REVIEWS DRUG DISCOVERY
- Antihyperalgesic effect of a Cannabis sativa extract in a rat model of neuropathic pain: mechanisms involved
- (2008) Francesca Comelli et al. PHYTOTHERAPY RESEARCH
- Involvement of 5HT1A receptors in the anxiolytic-like effects of cannabidiol injected into the dorsolateral periaqueductal gray of rats
- (2008) Alline Cristina Campos et al. PSYCHOPHARMACOLOGY
- Cannabidiol: from an inactive cannabinoid to a drug with wide spectrum of action
- (2008) Antonio Waldo Zuardi REVISTA BRASILEIRA DE PSIQUIATRIA
- Cannabidiol potentiates pharmacological effects of Δ9-tetrahydrocannabinol via CB1 receptor-dependent mechanism
- (2007) Kazuhide Hayakawa et al. BRAIN RESEARCH
- The diverse CB1and CB2receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin
- (2007) R G Pertwee BRITISH JOURNAL OF PHARMACOLOGY
- The psychoactive plant cannabinoid, Δ9-tetrahydrocannabinol, is antagonized by Δ8- and Δ9-tetrahydrocannabivarin in mice in vivo
- (2007) R G Pertwee et al. BRITISH JOURNAL OF PHARMACOLOGY
- Meta-analysis of cannabinoid ligand binding affinity and receptor distribution: interspecies differences
- (2007) J M McPartland et al. BRITISH JOURNAL OF PHARMACOLOGY
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