Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders

Cannabidivarin-rich cannabis extracts are anticonvulsant in mouse and rat via a CB1receptor-independent mechanism

(2013) T D M Hill et al.   BRITISH JOURNAL OF PHARMACOLOGY

TRPV1 antagonist capsazepine suppresses 4-AP-induced epileptiform activity in vitro and electrographic seizures in vivo

(2013) Luis E. Gonzalez-Reyes et al.   EXPERIMENTAL NEUROLOGY

A new multiple sclerosis spasticity treatment option: effect in everyday clinical practice and cost–effectiveness in Germany

(2013) Peter Flachenecker   Expert Review of Neurotherapeutics

The effect of cannabichromene on adult neural stem/progenitor cells

(2013) Noriko Shinjyo et al.   NEUROCHEMISTRY INTERNATIONAL

Mechanisms of cannabidiol neuroprotection in hypoxic–ischemic newborn pigs: Role of 5HT1A and CB2 receptors

(2013) M. Ruth Pazos et al.   NEUROPHARMACOLOGY

Direct modulation of the outer mitochondrial membrane channel, voltage-dependent anion channel 1 (VDAC1) by cannabidiol: a novel mechanism for cannabinoid-induced cell death

(2013) N Rimmerman et al.   Cell Death & Disease

Stiripentol: An example of antiepileptic drug development in childhood epilepsies

(2012) Rima Nabbout et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

Diagnosis and long-term course of Dravet syndrome

(2012) Ingrid E. Scheffer   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

Cannabidiol inhibits THC-elicited paranoid symptoms and hippocampal-dependent memory impairment

(2012) Amir Englund et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Cannabidiol administration after hypoxia–ischemia to newborn rats reduces long-term brain injury and restores neurobehavioral function

(2012) M.R. Pazos et al.   NEUROPHARMACOLOGY

Cannabidiol exhibits anxiolytic but not antipsychotic property evaluated in the social interaction test

(2012) Valéria Almeida et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures

(2012) Nicholas A. Jones et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia

(2012) F M Leweke et al.   Translational Psychiatry

Symptom-relieving and neuroprotective effects of the phytocannabinoid Δ9-THCV in animal models of Parkinson's disease

(2011) C García et al.   BRITISH JOURNAL OF PHARMACOLOGY

Insights into pathophysiology and therapy from a mouse model of Dravet syndrome

(2011) John C. Oakley et al.   EPILEPSIA

Cannabidiol Reduces the Anxiety Induced by Simulated Public Speaking in Treatment-Naïve Social Phobia Patients

(2011) Mateus M Bergamaschi et al.   NEUROPSYCHOPHARMACOLOGY

Cannabidiol Reduces Brain Damage and Improves Functional Recovery After Acute Hypoxia-Ischemia in Newborn Pigs

(2011) Hector Lafuente et al.   PEDIATRIC RESEARCH

Phytocannabinoids as novel therapeutic agents in CNS disorders

(2011) Andrew J. Hill et al.   PHARMACOLOGY & THERAPEUTICS

Anxiogenic-like effects of chronic cannabidiol administration in rats

(2011) Maha M. ElBatsh et al.   PSYCHOPHARMACOLOGY

Cannabis with high cannabidiol content is associated with fewer psychotic experiences

(2011) Christian D. Schubart et al.   SCHIZOPHRENIA RESEARCH

Supply and demand for endocannabinoids

(2011) Bradley E. Alger et al.   TRENDS IN NEUROSCIENCES

Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic study

(2010) Celia J. A. Morgan et al.   BRITISH JOURNAL OF PSYCHIATRY

Δ9-Tetrahydrocannabivarin suppresses in vitro epileptiform and in vivo seizure activity in adult rats

(2010) Andrew J. Hill et al.   EPILEPSIA

Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report

(2010) José Alexandre S Crippa et al.   JOURNAL OF PSYCHOPHARMACOLOGY

The role of inflammation in epilepsy

(2010) Annamaria Vezzani et al.   Nature Reviews Neurology

Pharmacological Treatment of Painful HIV-Associated Sensory Neuropathy: A Systematic Review and Meta-Analysis of Randomised Controlled Trials

(2010) Tudor J. C. Phillips et al.   PLoS One

Distinct Effects of Δ9-Tetrahydrocannabinol and Cannabidiol on Neural Activation During Emotional Processing

(2009) Paolo Fusar-Poli et al.   ARCHIVES OF GENERAL PSYCHIATRY

Cannabidiol Targets Mitochondria to Regulate Intracellular Ca2+ Levels

(2009) D. Ryan et al.   JOURNAL OF NEUROSCIENCE

Cannabidiol Displays Antiepileptiform and Antiseizure Properties In Vitro and In Vivo

(2009) N. A. Jones et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The neuroprotective effect of cannabidiol in an in vitro model of newborn hypoxic–ischemic brain damage in mice is mediated by CB2 and adenosine receptors

(2009) A. Castillo et al.   NEUROBIOLOGY OF DISEASE

Opposite Effects of Δ-9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology

(2009) Sagnik Bhattacharyya et al.   NEUROPSYCHOPHARMACOLOGY

Systematic Review and Meta-analysis of Cannabis Treatment for Chronic Pain

(2009) Eva Martín-Sánchez et al.   PAIN MEDICINE

Effects of Δ9-tetrahydrocannabivarin on [35S]GTPγS binding in mouse brain cerebellum and piriform cortex membranes

(2008) I Dennis et al.   BRITISH JOURNAL OF PHARMACOLOGY

Effects of cannabidiol on schizophrenia-like symptoms in people who use cannabis

(2008) Celia J. A. Morgan et al.   BRITISH JOURNAL OF PSYCHIATRY

Therapeutic use ofCannabis sativaon chemotherapy-induced nausea and vomiting among cancer patients: systematic review and meta-analysis

(2008) F.C. MACHADO ROCHA et al.   EUROPEAN JOURNAL OF CANCER CARE

The diverse CB1and CB2receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin

(2007) R G Pertwee   BRITISH JOURNAL OF PHARMACOLOGY

Cannabidiol-induced apoptosis in primary lymphocytes is associated with oxidative stress-dependent activation of caspase-8

(2007) Hsin-Ying Wu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY