The Metabolic Basis of Immune Dysfunction Following Sepsis and Trauma
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Title
The Metabolic Basis of Immune Dysfunction Following Sepsis and Trauma
Authors
Keywords
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Journal
Frontiers in Immunology
Volume 11, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-05-29
DOI
10.3389/fimmu.2020.01043
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Note: Only part of the references are listed.- Effects of Orally Administered Resveratrol on TNF, IL-1β, Leukocyte Phagocytic Activity and Oxidative Burst Function in Horses: A Prospective, Randomized, Double-Blinded, Placebo-Controlled Study
- (2020) Lynn M. Martin et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Frontline Science: Monocytes sequentially rewire metabolism and bioenergetics during an acute inflammatory response
- (2019) Xuewei Zhu et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Population-specific metabolic alterations in professional antigen-presenting cells contribute to sepsis-associated immunosuppression
- (2019) Judith Schenz et al. SHOCK
- Regulation of leukocyte function by citric acid cycle intermediates
- (2019) Naeem K. Patil et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Peripheral Blood Mononuclear Cells Demonstrate Mitochondrial Damage Clearance During Sepsis
- (2019) Bryan D. Kraft et al. CRITICAL CARE MEDICINE
- One-hit wonder: Late after burn injury, granulocytes can clear one bacterial infection but cannot control a subsequent infection
- (2019) Laurel B. Kartchner et al. BURNS
- Protective effects of resveratrol on acute kidney injury in rats with sepsis
- (2019) Cong-Juan Luo et al. BIOMEDICAL PAPERS-OLOMOUC
- Mitochondrial electron transport chain, ROS generation and uncoupling (Review)
- (2019) Ru‑Zhou Zhao et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Human and murine macrophages exhibit differential metabolic responses to lipopolysaccharide - A divergent role for glycolysis
- (2019) Vijith Vijayan et al. Redox Biology
- Regulation of Mitochondrial Biogenesis as a Way for Active Longevity: Interaction Between the Nrf2 and PGC-1α Signaling Pathways
- (2019) Artem P. Gureev et al. Frontiers in Genetics
- S-glycosylation-based cysteine profiling reveals regulation of glycolysis by itaconate
- (2019) Wei Qin et al. Nature Chemical Biology
- Traumatic Injury and Exposure to Mitochondrial-Derived Damage Associated Molecular Patterns Suppresses Neutrophil Extracellular Trap Formation
- (2019) Jon Hazeldine et al. Frontiers in Immunology
- Persistent Mitochondrial Dysfunction Linked to Prolonged Organ Dysfunction in Pediatric Sepsis
- (2019) Scott L. Weiss et al. CRITICAL CARE MEDICINE
- Phosphorylated Hexa-Acyl Disaccharides Augment Host Resistance Against Common Nosocomial Pathogens
- (2019) Antonio Hernandez et al. CRITICAL CARE MEDICINE
- Autocrine IFN-I inhibits isocitrate dehydrogenase in the TCA cycle of LPS-stimulated macrophages
- (2019) David P. De Souza et al. JOURNAL OF CLINICAL INVESTIGATION
- S100A9 maintains myeloid-derived suppressor cells in chronic sepsis by inducing miR-21 and miR-181b
- (2019) Tuqa Alkhateeb et al. MOLECULAR IMMUNOLOGY
- β-Glucan-Induced Trained Immunity Protects against Leishmania braziliensis Infection: a Crucial Role for IL-32
- (2019) Jéssica Cristina dos Santos et al. Cell Reports
- AGER-Mediated Lipid Peroxidation Drives Caspase-11 Inflammasome Activation in Sepsis
- (2019) Ruochan Chen et al. Frontiers in Immunology
- Serum Levels of Mitochondrial and Microbial Metabolites Reflect Mitochondrial Dysfunction in Different Stages of Sepsis
- (2019) Beloborodova et al. Metabolites
- Thiazolidinediones: the Forgotten Diabetes Medications
- (2019) Harold E. Lebovitz Current Diabetes Reports
- Endogenous oxidized phospholipids reprogram cellular metabolism and boost hyperinflammation
- (2019) Marco Di Gioia et al. NATURE IMMUNOLOGY
- MITOCHONDRIAL DYSFUNCTION IS ASSOCIATED WITH AN IMMUNE PARALYSIS PHENOTYPE IN PEDIATRIC SEPSIS
- (2019) Scott L. Weiss et al. SHOCK
- 4-Octyl itaconate inhibits aerobic glycolysis by targeting GAPDH to exert anti-inflammatory effects
- (2019) Shan-Ting Liao et al. Nature Communications
- Metformin Improves Mitochondrial Respiratory Activity through Activation of AMPK
- (2019) Yu Wang et al. Cell Reports
- Mechanism of pulmonary immunosuppression: extrapulmonary burn injury suppresses bacterial endotoxin–induced pulmonary neutrophil recruitment and neutrophil extracellular trap (NET) formation
- (2019) Miyuki Sakuma et al. FASEB JOURNAL
- Deoxyelephantopin decreases the release of inflammatory cytokines in macrophage associated with attenuation of aerobic glycolysis via modulation of PKM2
- (2019) Lanlan Pan et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Suppressive Effects of GSS on Lipopolysaccharide-Induced Endothelial Cell Injury and ALI via TNF-α and IL-6
- (2019) Lei Yi et al. MEDIATORS OF INFLAMMATION
- Immunobiology and application of toll-like receptor 4 agonists to augment host resistance to infection
- (2019) Antonio Hernandez et al. PHARMACOLOGICAL RESEARCH
- Resveratrol Protects the Myocardium in Sepsis by Activating the Phosphatidylinositol 3-Kinases (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Pathway and Inhibiting the Nuclear Factor-κB (NF-κB) Signaling Pathway
- (2019) Xiuling Shang et al. MEDICAL SCIENCE MONITOR
- Age-Dependent Cardiac Function during Experimental Sepsis: Effect of Pharmacological Activation of AMP-Activated Protein Kinase by AICAR
- (2018) Yu Inata et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- PDE/cAMP/Epac/C/EBP-β Signaling Cascade Regulates Mitochondria Biogenesis of Tubular Epithelial Cells in Renal Fibrosis
- (2018) Hao Ding et al. ANTIOXIDANTS & REDOX SIGNALING
- Reprogramming of basic metabolic pathways in microbial sepsis: therapeutic targets at last?
- (2018) Lise Van Wyngene et al. EMBO Molecular Medicine
- The AMPK agonist 5‐aminoimidazole‐4‐carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation‐associated cachectic muscle wasting
- (2018) Derek T Hall et al. EMBO Molecular Medicine
- The TLR4 Agonist Monophosphoryl Lipid A Drives Broad Resistance to Infection via Dynamic Reprogramming of Macrophage Metabolism
- (2018) Benjamin A. Fensterheim et al. JOURNAL OF IMMUNOLOGY
- Long-term reprogramming of the innate immune system
- (2018) Jorge Dominguez-Andres et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Beyond a neurotransmitter: The role of serotonin in inflammation and immunity
- (2018) Hera Wu et al. PHARMACOLOGICAL RESEARCH
- Alterations in Mitochondrial Function in Blood Cells Obtained from Patients with Sepsis Presenting to an Emergency Department
- (2018) David H. Jang et al. SHOCK
- Septic Shock Alters Mitochondrial Respiration of Lymphoid Cell-Lines and Human Peripheral Blood Mononuclear Cells
- (2018) Raphael Clere-Jehl et al. SHOCK
- The oxidized phospholipid oxPAPC protects from septic shock by targeting the non-canonical inflammasome in macrophages
- (2018) Lan H. Chu et al. Nature Communications
- A Role for the Krebs Cycle Intermediate Citrate in Metabolic Reprogramming in Innate Immunity and Inflammation
- (2018) Niamh C. Williams et al. Frontiers in Immunology
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- (2018) Giorgio Camilli et al. Frontiers in Immunology
- The Glyoxylate Shunt, 60 Years On
- (2018) Stephen K. Dolan et al. Annual Review of Microbiology
- Glycolytic Stimulation Is Not a Requirement for M2 Macrophage Differentiation
- (2018) Feilong Wang et al. Cell Metabolism
- Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
- (2018) Evanna L. Mills et al. NATURE
- Resveratrol ameliorates sepsis‑induced acute kidney injury in a pediatric rat model via Nrf2 signaling pathway
- (2018) Yan Wang et al. Experimental and Therapeutic Medicine
- Itaconic acid indicates cellular but not systemic immune system activation
- (2018) Johannes Meiser et al. Oncotarget
- Hypoxia-inducible factor-1α regulation of myeloid cells
- (2018) C. L. Stothers et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Metformin attenuated endotoxin-induced acute myocarditis via activating AMPK
- (2017) Gang Liu et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Targeting Immune Cell Checkpoints during Sepsis
- (2017) Naeem Patil et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Cytokine Response to Lipopolysaccharide Does Not Predict the Host Response to Infection
- (2017) Benjamin A. Fensterheim et al. JOURNAL OF IMMUNOLOGY
- Frontline Science: Anti-PD-L1 protects against infection with common bacterial pathogens after burn injury
- (2017) Naeem K. Patil et al. JOURNAL OF LEUKOCYTE BIOLOGY
- AMPK: guardian of metabolism and mitochondrial homeostasis
- (2017) Sébastien Herzig et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mitochondrial function of immune cells in septic shock: A prospective observational cohort study
- (2017) Tobias M. Merz et al. PLoS One
- Metformin ameliorates sepsis-induced brain injury by inhibiting apoptosis, oxidative stress and neuroinflammation via the PI3K/Akt signaling pathway
- (2017) Guangming Tang et al. Oncotarget
- Resveratrol protects against early polymicrobial sepsis-induced acute kidney injury through inhibiting endoplasmic reticulum stress-activated NF-κB pathway
- (2017) Nian Wang et al. Oncotarget
- Rolipram Improves Outcome in a Rat Model of Infant Sepsis-Induced Cardiorenal Syndrome
- (2017) Clark R. Sims et al. Frontiers in Pharmacology
- Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages
- (2016) Evanna L. Mills et al. CELL
- Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation
- (2016) Vicky Lampropoulou et al. Cell Metabolism
- Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity
- (2016) Rob J.W. Arts et al. Cell Metabolism
- Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome
- (2016) Bita Shakoory et al. CRITICAL CARE MEDICINE
- Cardioprotective effect of metformin in lipopolysaccharide-induced sepsis via suppression of toll-like receptor 4 (TLR4) in heart
- (2016) Haleh Vaez et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Directly interact with Keap1 and LPS is involved in the anti-inflammatory mechanisms of (-)-epicatechin-3-gallate in LPS-induced macrophages and endotoxemia
- (2016) Yi-Shiou Chiou et al. FREE RADICAL BIOLOGY AND MEDICINE
- AMPK activation by metformin inhibits local innate immune responses in the isolated rat heart by suppression of TLR 4-related pathway
- (2016) Haleh Vaez et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Antimicrobial Resistance
- (2016) Hilary D. Marston et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
- (2016) Mervyn Singer et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Immunoresponsive Gene 1 and Itaconate Inhibit Succinate Dehydrogenase to Modulate Intracellular Succinate Levels
- (2016) Thekla Cordes et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The role of MyD88- and TRIF-dependent signaling in monophosphoryl lipid A-induced expansion and recruitment of innate immunocytes
- (2016) Antonio Hernandez et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Frontline Science: Defects in immune function in patients with sepsis are associated with PD-1 or PD-L1 expression and can be restored by antibodies targeting PD-1 or PD-L1
- (2016) Andriani C. Patera et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Development of Therapeutics That Induce Mitochondrial Biogenesis for the Treatment of Acute and Chronic Degenerative Diseases
- (2016) Robert B. Cameron et al. JOURNAL OF MEDICINAL CHEMISTRY
- Metformin protects against infection-induced myocardial dysfunction
- (2016) Theodora Tzanavari et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis
- (2016) Shih-Chin Cheng et al. NATURE IMMUNOLOGY
- Trained immunity: A program of innate immune memory in health and disease
- (2016) M. G. Netea et al. SCIENCE
- Mitochondrial Function in Sepsis
- (2016) Nishkantha Arulkumaran et al. SHOCK
- IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid
- (2016) Jan Naujoks et al. PLoS Pathogens
- Genomic landscape of the individual host response and outcomes in sepsis: a prospective cohort study
- (2016) Emma E Davenport et al. Lancet Respiratory Medicine
- Remote Ischemic Conditioning Prevents Lung and Liver Injury After Hemorrhagic Shock/Resuscitation
- (2015) Chung Ho Leung et al. ANNALS OF SURGERY
- Itaconic Acid: The Surprising Role of an Industrial Compound as a Mammalian Antimicrobial Metabolite
- (2015) Thekla Cordes et al. Annual Review of Nutrition
- Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages
- (2015) Eva M. Palsson-McDermott et al. Cell Metabolism
- The Epidemiology of Chronic Critical Illness in the United States*
- (2015) Jeremy M. Kahn et al. CRITICAL CARE MEDICINE
- Cytomegalovirus Infection Drives Adaptive Epigenetic Diversification of NK Cells with Altered Signaling and Effector Function
- (2015) Heinrich Schlums et al. IMMUNITY
- Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization
- (2015) Abhishek K. Jha et al. IMMUNITY
- Human Monocytes Undergo Functional Re-programming during Sepsis Mediated by Hypoxia-Inducible Factor-1α
- (2015) Irina N. Shalova et al. IMMUNITY
- Novel Programs and Discoveries Aim to Combat Antibiotic Resistance
- (2015) Tracy Hampton JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- IL-33 Receptor ST2 Amplifies the Expansion of NK Cells and Enhances Host Defense during Mouse Cytomegalovirus Infection
- (2015) Tsukasa Nabekura et al. JOURNAL OF IMMUNOLOGY
- Role of G-CSF in monophosphoryl lipid A-mediated augmentation of neutrophil functions after burn injury
- (2015) Julia K. Bohannon et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Daidzein pretreatment improves survival in mouse model of sepsis
- (2015) Subhashree Parida et al. JOURNAL OF SURGICAL RESEARCH
- Adenosine monophosphate-activated protein kinase activation protects against sepsis-induced organ injury and inflammation
- (2015) Daniel A. Escobar et al. JOURNAL OF SURGICAL RESEARCH
- Mitochondrial Dysfunction in Peripheral Blood Mononuclear Cells in Pediatric Septic Shock*
- (2015) Scott L. Weiss et al. Pediatric Critical Care Medicine
- Getting sepsis therapy right
- (2015) R. S. Hotchkiss et al. SCIENCE
- Mitochondrial ROS Induces Cardiac Inflammation via a Pathway through mtDNA Damage in a Pneumonia-Related Sepsis Model
- (2015) Xiao Yao et al. PLoS One
- Energy crisis: The role of oxidative phosphorylation in acute inflammation and sepsis
- (2014) Icksoo Lee et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Fibrates ameliorate the course of bacterial sepsis by promoting neutrophil recruitment via CXCR2
- (2014) Ivan Tancevski et al. EMBO Molecular Medicine
- Epigenetic coordination of acute systemic inflammation: potential therapeutic targets
- (2014) Vidula Vachharajani et al. Expert Review of Clinical Immunology
- Metformin Activates AMP-activated Protein Kinase by Promoting Formation of the αβγ Heterotrimeric Complex
- (2014) Shumei Meng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Heterologous Immunological Effects of Early BCG Vaccination in Low-Birth-Weight Infants in Guinea-Bissau: A Randomized-controlled Trial
- (2014) Kristoffer Jarlov Jensen et al. JOURNAL OF INFECTIOUS DISEASES
- Intraperitoneal prophylaxis with CpG oligodeoxynucleotides protects neutropenic mice against intracerebral Escherichia coli K1 infection
- (2014) Sandra Ribes et al. Journal of Neuroinflammation
- Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
- (2014) Edward T. Chouchani et al. NATURE
- Bacterial itaconate degradation promotes pathogenicity
- (2014) Jahminy Sasikaran et al. Nature Chemical Biology
- Neutrophils prime a long-lived effector macrophage phenotype that mediates accelerated helminth expulsion
- (2014) Fei Chen et al. NATURE IMMUNOLOGY
- Advances in targeting cyclic nucleotide phosphodiesterases
- (2014) Donald H. Maurice et al. NATURE REVIEWS DRUG DISCOVERY
- Protective Effect of DNA Vaccine Encoding Pseudomonas Exotoxin A and PcrV against Acute Pulmonary P. aeruginosa Infection
- (2014) Mingzi Jiang et al. PLoS One
- mTOR- and HIF-1 -mediated aerobic glycolysis as metabolic basis for trained immunity
- (2014) S.-C. Cheng et al. SCIENCE
- Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity
- (2014) S. Saeed et al. SCIENCE
- Malaria-Induced NLRP12/NLRP3-Dependent Caspase-1 Activation Mediates Inflammation and Hypersensitivity to Bacterial Superinfection
- (2014) Marco A. Ataide et al. PLoS Pathogens
- An Endotoxin Tolerance Signature Predicts Sepsis and Organ Dysfunction at Initial Clinical Presentation
- (2014) Olga M. Pena et al. EBioMedicine
- Cilostazol promotes mitochondrial biogenesis in human umbilical vein endothelial cells through activating the expression of PGC-1α
- (2013) Luning Zuo et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Epigallocatechin-3-gallate prevents oxidative phosphorylation deficit and promotes mitochondrial biogenesis in human cells from subjects with Down's syndrome
- (2013) Daniela Valenti et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- The Warburg effect then and now: From cancer to inflammatory diseases
- (2013) Eva M. Palsson-McDermott et al. BIOESSAYS
- Peroxisome Proliferator–Activated Receptor-γ Activation Prevents Sepsis-Related Cardiac Dysfunction and Mortality In Mice
- (2013) Konstantinos Drosatos et al. Circulation-Heart Failure
- Training innate immunity: the changing concept of immunological memory in innate host defence
- (2013) Mihai G. Netea EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- Toll-like receptor-4 agonist in post-haemorrhage pneumonia: role of dendritic and natural killer cells
- (2013) Antoine Roquilly et al. EUROPEAN RESPIRATORY JOURNAL
- Report Reveals Scope of US Antibiotic Resistance Threat
- (2013) Tracy Hampton JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Lipopolysaccharide Clearance, Bacterial Clearance, and Systemic Inflammatory Responses Are Regulated by Cell Type-Specific Functions of TLR4 during Sepsis
- (2013) M. Deng et al. JOURNAL OF IMMUNOLOGY
- Dectin-1 plays a redundant role in the immunomodulatory activities of β-glucan-rich ligands in vivo
- (2013) Mohlopheni J. Marakalala et al. MICROBES AND INFECTION
- Succinate is an inflammatory signal that induces IL-1β through HIF-1α
- (2013) G. M. Tannahill et al. NATURE
- Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production
- (2013) A. Michelucci et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Immunobiology of Toll-Like Receptor 4 Agonists
- (2013) Julia K. Bohannon et al. SHOCK
- Succinate: a metabolic signal in inflammation
- (2013) Evanna Mills et al. TRENDS IN CELL BIOLOGY
- A small jab – a big effect: nonspecific immunomodulation by vaccines
- (2013) Christine S. Benn et al. TRENDS IN IMMUNOLOGY
- Mitochondrial Biogenesis through Activation of Nuclear Signaling Proteins
- (2013) J. E. Dominy et al. Cold Spring Harbor Perspectives in Biology
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- (2013) Mervyn Singer Virulence
- The Sedoheptulose Kinase CARKL Directs Macrophage Polarization through Control of Glucose Metabolism
- (2012) Arvand Haschemi et al. Cell Metabolism
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- (2012) Virginia Vanasco et al. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- Phosphodiesterase-4 inhibition as a therapeutic approach to treat capillary leakage in systemic inflammation
- (2012) Martin Alexander Schick et al. JOURNAL OF PHYSIOLOGY-LONDON
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- (2012) Lorenzo Galluzzi et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Prophylactic Application of CpG Oligonucleotides Augments the Early Host Response and Confers Protection in Acute Melioidosis
- (2012) Barbara M. Judy et al. PLoS One
- Bacille Calmette-Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes
- (2012) J. Kleinnijenhuis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Type I Interferons Promote Fatal Immunopathology by Regulating Inflammatory Monocytes and Neutrophils during Candida Infections
- (2012) Olivia Majer et al. PLoS Pathogens
- Regulation of PGC-1α, a nodal regulator of mitochondrial biogenesis
- (2011) Pablo J Fernandez-Marcos et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- The mitochondrial citrate carrier: a new player in inflammation
- (2011) Vittoria Infantino et al. BIOCHEMICAL JOURNAL
- Immunopathogenesis of ischemia/reperfusion-associated tissue damage
- (2011) Antonis Ioannou et al. CLINICAL IMMUNOLOGY
- Bioenergetic failure of human peripheral blood monocytes in patients with septic shock is mediated by reduced F1Fo adenosine-5′-triphosphate synthase activity*
- (2011) André M. Japiassú et al. CRITICAL CARE MEDICINE
- 5-HT and the immune system
- (2011) Gerard P Ahern CURRENT OPINION IN PHARMACOLOGY
- Monophosphoryl lipid A induced innate immune responses via TLR4 to enhance clearance of nontypeableHaemophilus influenzaeandMoraxella catarrhalisfrom the nasopharynx in mice
- (2011) Takashi Hirano et al. FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY
- The Toll-Like Receptor 4 Agonist Monophosphoryl Lipid A Augments Innate Host Resistance to Systemic Bacterial Infection
- (2011) Christopher D. Romero et al. INFECTION AND IMMUNITY
- The role of toll-like receptor-4 in the development of multi-organ failure following traumatic haemorrhagic shock and resuscitation
- (2011) Lee J. McGhan et al. INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
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- (2011) Glòria Garrabou et al. JOURNAL OF INFECTIOUS DISEASES
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- (2011) Yukihiro Tsujimura et al. JOURNAL OF SURGICAL RESEARCH
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- (2011) Masahiro Sugimoto et al. Metabolomics
- TLR signalling augments macrophage bactericidal activity through mitochondrial ROS
- (2011) A. Phillip West et al. NATURE
- Reduced Peroxisome Proliferator-Activated Receptor α Expression Is Associated With Decreased Survival and Increased Tissue Bacterial Load in Sepsis
- (2011) Stephen W. Standage et al. SHOCK
- AMPK and SIRT1: a long-standing partnership?
- (2010) Neil B. Ruderman et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Serotonin activates murine alveolar macrophages through 5-HT2C receptors
- (2010) Zbigniew Mikulski et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Survival in Critical Illness Is Associated with Early Activation of Mitochondrial Biogenesis
- (2010) Jane E. Carré et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network
- (2010) Richard C. Scarpulla BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Resveratrol induces mitochondrial biogenesis and ameliorates Ang II-induced cardiac remodeling in transgenic rats harboring human renin and angiotensinogen genes
- (2010) Agnieszka Biala et al. BLOOD PRESSURE
- Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists
- (2009) Jörg Vollmer et al. ADVANCED DRUG DELIVERY REVIEWS
- Transcriptional Control of Mitochondrial Biogenesis and Function
- (2009) M. Benjamin Hock et al. Annual Review of Physiology
- Clinical practice parameters for hemodynamic support of pediatric and neonatal septic shock: 2007 update from the American College of Critical Care Medicine*
- (2009) Joe Brierley et al. CRITICAL CARE MEDICINE
- The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex
- (2009) Beom Seok Park et al. NATURE
- AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
- (2009) Carles Cantó et al. NATURE
- ENDOTOXIN PRETREATMENT IMPROVES BACTERIAL CLEARANCE AND DECREASES MORTALITY IN MICE CHALLENGED WITH STAPHYLOCOCCUS AUREUS
- (2009) E.D. Murphey et al. SHOCK
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- (2009) Concetta Crisafulli et al. SHOCK
- Endotoxin tolerance: new mechanisms, molecules and clinical significance
- (2009) Subhra K. Biswas et al. TRENDS IN IMMUNOLOGY
- The Compensatory Anti-inflammatory Response Syndrome (CARS) in Critically Ill Patients
- (2008) Nicholas S. Ward et al. CLINICS IN CHEST MEDICINE
- Dietary Phytoestrogens Activate AMP-Activated Protein Kinase With Improvement in Lipid and Glucose Metabolism
- (2008) C. R. Cederroth et al. DIABETES
- ACCM/PALS haemodynamic support guidelines for paediatric septic shock: an outcomes comparison with and without monitoring central venous oxygen saturation
- (2008) Cláudio F. de Oliveira et al. INTENSIVE CARE MEDICINE
- Gain-of-function R225Q Mutation in AMP-activated Protein Kinase γ3 Subunit Increases Mitochondrial Biogenesis in Glycolytic Skeletal Muscle
- (2008) Pablo M. Garcia-Roves et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Transcriptional Paradigms in Mammalian Mitochondrial Biogenesis and Function
- (2008) Richard C. Scarpulla PHYSIOLOGICAL REVIEWS
- INDUCTION OF ENDOTOXIN TOLERANCE ENHANCES BACTERIAL CLEARANCE AND SURVIVAL IN MURINE POLYMICROBIAL SEPSIS
- (2008) Derek S. Wheeler et al. SHOCK
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