Environmentally-Safe Conditions for a Palladium-Catalyzed Direct C3-Arylation with High Turn Over Frequency of Imidazo[1,2-b ]pyridazines Using Aryl Bromides and Chlorides

Regioselectivity in palladium-catalysed direct arylation of 5-membered ring heteroaromatics

(2016) Charles Beromeo Bheeter et al.   Catalysis Science & Technology

Direct access to 2-(hetero)arylated pyridines from 6-substituted 2-bromopyridines via phosphine-free palladium-catalyzed C–H bond arylations: the importance of the C6 substituent

(2016) Wided Hagui et al.   RSC Advances

Recent Advances in Copper-mediated Direct Biaryl Coupling

(2015) Koji Hirano et al.   CHEMISTRY LETTERS

Eco-Friendly Solvents for Palladium-Catalyzed Desulfitative CH Bond Arylation of Heteroarenes

(2015) Anoir Hfaiedh et al.   ChemSusChem

Dimethyl carbonate and switchable anionic surfactants: two effective tools for the extraction of polyhydroxyalkanoates from microbial biomass

(2015) Chiara Samorì et al.   GREEN CHEMISTRY

Discovery of Imidazo[1,2-b]pyridazine Derivatives: Selective and Orally Available Mps1 (TTK) Kinase Inhibitors Exhibiting Remarkable Antiproliferative Activity

(2015) Ken-ichi Kusakabe et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and characterization of hexaarylbenzenes with five or six different substituents enabled by programmed synthesis

(2015) Shin Suzuki et al.   Nature Chemistry

Chloride-promoted Pd-catalyzed direct C–H arylation for highly efficient phosphine-free synthesis of π-conjugated polymers

(2015) Shotaro Hayashi et al.   Polymer Chemistry

Functionalization of C–H Bonds via Metal-Catalyzed Desulfitative Coupling: An Alternative Tool for Access to Aryl- or Alkyl-Substituted (Hetero)arenes

(2015) Kedong Yuan et al.   ACS Catalysis

Palladium-Catalysed Direct Arylation using Free-Amine-Substituted Polyfluoroanilines with Inhibition of Amination-Type Reaction

(2015) Abdelilah Takfaoui et al.   Asian Journal of Organic Chemistry

Reusable and Removable Directing Groups for C(sp2)−H Bond Functionalization of Arenes

(2015) M. Ramu Yadav et al.   Asian Journal of Organic Chemistry

Cross-Coupling of Heteroarenes by CH Functionalization: Recent Progress towards Direct Arylation and Heteroarylation Reactions Involving Heteroarenes Containing One Heteroatom

(2014) Renzo Rossi et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis of (Poly)fluorobiphenyls through Metal-catalyzed CH Bond Activation/Arylation of (Poly)fluorobenzene Derivatives

(2014) Mian He et al.   ChemCatChem

Influence of the solvent and of the reaction concentration for palladium-catalysed direct arylation of heteroaromatics with 4-bromoacetophenone

(2014) Souhila Bensaid et al.   COMPTES RENDUS CHIMIE

Direct C–H Bond Arylation of (Benzo)oxazoles with Aryl Chlorides Catalyzed by N-Heterocyclic Carbene–Palladium(II)–1-Methylimidazole Complex

(2014) Xiao-Bao Shen et al.   ORGANIC LETTERS

Recent advances in directed C–H functionalizations using monodentate nitrogen-based directing groups

(2014) Min Zhang et al.   Organic Chemistry Frontiers

Synthesis of 2,5-Diarylpyrroles by Ligand-Free Palladium-Catalyzed CH Activation of Pyrroles in Ionic Liquids

(2013) Peter Ehlers et al.   ChemCatChem

“On Water”, Phosphine-Free Palladium-Catalyzed Room Temperature CH Arylation of Indoles

(2013) Saidul Islam et al.   CHEMISTRY-A EUROPEAN JOURNAL

Beyond Directing Groups: Transition-Metal-Catalyzed CH Activation of Simple Arenes

(2012) Nadine Kuhl et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

CH Bond Functionalization: Emerging Synthetic Tools for Natural Products and Pharmaceuticals

(2012) Junichiro Yamaguchi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

From C(sp2)–H to C(sp3)–H: systematic studies on transition metal-catalyzed oxidative C–C formation

(2012) Bi-Jie Li et al.   CHEMICAL SOCIETY REVIEWS

Discovery of a Full-Color-Tunable Fluorescent Core Framework through Direct CH (Hetero)arylation of N-Heterocycles

(2012) Bo Liu et al.   CHEMISTRY-A EUROPEAN JOURNAL

“On water” direct Pd-catalysed C–H arylation of thiazolo[5,4-d]pyrimidine derivatives

(2012) Ye-Xiang Su et al.   GREEN CHEMISTRY

Phosphine-Free Palladium-Catalyzed Direct Arylation of Imidazo[1,2-a]pyridines with Aryl Bromides at Low Catalyst Loading

(2012) Hai Yan Fu et al.   JOURNAL OF ORGANIC CHEMISTRY

Efficient Pd-Catalyzed Direct Arylations of Heterocycles with Unreactive and Hindered Aryl Chlorides

(2012) Debalina Ghosh et al.   ORGANIC LETTERS

Ruthenium-catalyzed direct oxidative alkenylation of arenes through twofold C–H bond functionalization

(2012) Sergei I. Kozhushkov et al.   Chemical Science

Palladium-Catalyzed Direct Arylation of Heteroaromatics with Activated Aryl Chlorides Using a Sterically Relieved Ferrocenyl-Diphosphane

(2012) David Roy et al.   ACS Catalysis

Highly regioselective C–H bond functionalization: palladium-catalyzed arylation of substituted imidazo[1,2-a]pyridine with aryl chlorides

(2012) Hua Cao et al.   RSC Advances

Glycerol and derived solvents: new sustainable reaction media for organic synthesis

(2011) Alba E. Díaz-Álvarez et al.   CHEMICAL COMMUNICATIONS

Recent advances in the transition metal-catalyzed twofold oxidative C–H bond activation strategy for C–C and C–N bond formation

(2011) Seung Hwan Cho et al.   CHEMICAL SOCIETY REVIEWS

Mechanism Selection for Regiocontrol in Base-Assisted, Palladium-Catalysed Direct CH Coupling with Halides: First Approach for Oxazole- and Thiazole-4-Carboxylates

(2011) Laure Théveau et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cyclopentyl Methyl Ether: An Alternative Solvent for Palladium-Catalyzed Direct Arylation of Heteroaromatics

(2011) Kassem Beydoun et al.   ChemSusChem

Greener solvents for ruthenium and palladium-catalysed aromatic C–H bond functionalisation

(2011) Cedric Fischmeister et al.   GREEN CHEMISTRY

Expanding GSK's solvent selection guide – embedding sustainability into solvent selection starting at medicinal chemistry

(2011) Richard K. Henderson et al.   GREEN CHEMISTRY

Congested Ferrocenyl Polyphosphanes Bearing Electron-Donating or Electron-Withdrawing Phosphanyl Groups: Assessment of Metallocene Conformation from NMR Spin Couplings and Use in Palladium-Catalyzed Chloroarenes Activation

(2011) Sophal Mom et al.   INORGANIC CHEMISTRY

Direct Arylation of Simple Azoles Catalyzed by 1,10-Phenanthroline Containing Palladium Complexes: An Investigation of C4 Arylation of Azoles and the Synthesis of Triarylated Azoles by Sequential Arylation

(2011) Fumitoshi Shibahara et al.   JOURNAL OF ORGANIC CHEMISTRY

Direct C5-Arylation Reaction between Imidazoles and Aryl Chlorides Catalyzed by Palladium Complexes with Phosphines and N-Heterocyclic Carbenes

(2011) P. Vijaya Kumar et al.   ORGANOMETALLICS

Palladium-catalysed direct arylations of heteroaromatics using more eco-compatible solvents pentan-1-ol or 3-methylbutan-1-ol

(2011) Souhila Bensaid et al.   TETRAHEDRON LETTERS

CH Bond Functionalization in Water Catalyzed by Carboxylato Ruthenium(II) Systems

(2010) Percia B. Arockiam et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Versatile Palladium/Triphosphane System for Direct Arylation of Heteroarenes with Chloroarenes at Low Catalyst Loading

(2010) David Roy et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pd-catalyzed oxidative coupling with organometallic reagents via C–H activation

(2010) Chang-Liang Sun et al.   CHEMICAL COMMUNICATIONS

Organic Carbonates as Solvents in Synthesis and Catalysis

(2010) Benjamin Schäffner et al.   CHEMICAL REVIEWS

Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions

(2010) Thomas W. Lyons et al.   CHEMICAL REVIEWS

Direct Arylation of Imidazo[1,2-b]pyridazines: Microwave-Assisted One-Pot Suzuki Coupling/Pd-Catalysed Arylation

(2010) Ahmed El Akkaoui et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Carbonates: eco-friendly solvents for palladium-catalysed direct arylation of heteroaromatics

(2010) Jia Jia Dong et al.   GREEN CHEMISTRY

Transition-Metal-Catalyzed Regioselective Arylation and Vinylation of Carboxylic Acids

(2010) Tetsuya Satoh et al.   SYNTHESIS-STUTTGART

Transition-Metal-Catalyzed Direct Arylation of (Hetero)Arenes by CH Bond Cleavage

(2009) Lutz Ackermann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium(II)-Catalyzed CH Activation/CC Cross-Coupling Reactions: Versatility and Practicality

(2009) Xiao Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed C3 or C4 Direct Arylation of Heteroaromatic Compounds with Aryl Halides by CH Bond Activation

(2009) Julien Roger et al.   ChemCatChem

The synthesis of organic carbonates from carbon dioxide

(2009) Toshiyasu Sakakura et al.   CHEMICAL COMMUNICATIONS

Phosphine-Free, Palladium-Catalyzed Arylation of Heterocycles through CH Bond Activation with Pivalic Acid as a Cocatalyst

(2009) Dongbing Zhao et al.   CHEMISTRY-A EUROPEAN JOURNAL

Low catalyst loading ligand-free palladium-catalyzed direct arylation of furans: an economically and environmentally attractive access to 5-arylfurans

(2009) Jia Jia Dong et al.   GREEN CHEMISTRY

Diethyl carbonate as a solvent for ruthenium catalysed C–H bond functionalisation

(2009) Percia Arockiam et al.   GREEN CHEMISTRY

A site selective C–H arylation of free-(NH2) adenines with aryl chlorides: Application to the synthesis of 6,8-disubstituted adenines

(2009) Sophian Sahnoun et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Catalytic Direct Arylations in Polyethylene Glycol (PEG): Recyclable Palladium(0) Catalyst for C−H Bond Cleavages in the Presence of Air

(2009) Lutz Ackermann et al.   ORGANIC LETTERS

Recent advances in the synthesis of (hetero)aryl-substituted heteroarenes via transition metal-catalysed direct (hetero)arylation of heteroarene C–H bonds with aryl halides or pseudohalides, diaryliodonium salts, and potassium aryltrifluoroborates

(2009) Fabio Bellina et al.   TETRAHEDRON

Palladium-Catalyzed Direct Arylations of 1,2,3-Triazoles with Aryl Chlorides using Conventional Heating

(2008) Lutz Ackermann et al.   ADVANCED SYNTHESIS & CATALYSIS

Direct arylations on water: synthesis of 2,5-disubstituted oxazoles balsoxin and texaline

(2008) Stephan A. Ohnmacht et al.   CHEMICAL COMMUNICATIONS

Transition-Metal-Catalyzed Carbon-Carbon Bond Formation via Carbon-Hydrogen Bond Cleavage

(2008) Fumitoshi Kakiuchi et al.   SYNTHESIS-STUTTGART

Green chemistry tools to influence a medicinal chemistry and research chemistry based organisation

(2007) Kim Alfonsi et al.   GREEN CHEMISTRY