In Vitro Blood–Brain Barrier-Integrated Neurological Disorder Models Using a Microfluidic Device
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
In Vitro Blood–Brain Barrier-Integrated Neurological Disorder Models Using a Microfluidic Device
Authors
Keywords
-
Journal
Micromachines
Volume 11, Issue 1, Pages 21
Publisher
MDPI AG
Online
2019-12-24
DOI
10.3390/mi11010021
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Human pluripotent stem cell–derived brain pericyte–like cells induce blood-brain barrier properties
- (2019) Matthew J. Stebbins et al. Science Advances
- Current trends and challenges in cancer management and therapy using designer nanomaterials
- (2019) P. N. Navya et al. Nano Convergence
- Hybrid elastomer–plastic microfluidic device as a convenient model for mimicking the blood–brain barrier in vitro
- (2019) Phuoc Quang Huy Nguyen et al. BIOMEDICAL MICRODEVICES
- Establishment of a Human iPSC- and Nanofiber-Based Microphysiological Blood–Brain Barrier System
- (2018) Dianjun Qi et al. ACS Applied Materials & Interfaces
- Ferritin Nanocarrier Traverses the Blood Brain Barrier and Kills Glioma
- (2018) Kelong Fan et al. ACS Nano
- 3D neural tissue models: From spheroids to bioprinting
- (2018) Pei Zhuang et al. BIOMATERIALS
- 3D self-organized microvascular model of the human blood-brain barrier with endothelial cells, pericytes and astrocytes
- (2018) Marco Campisi et al. BIOMATERIALS
- Microfluidic platforms for the study of neuronal injury in vitro
- (2018) Anil B. Shrirao et al. BIOTECHNOLOGY AND BIOENGINEERING
- Natural Products for Drug Discovery in the 21st Century: Innovations for Novel Drug Discovery
- (2018) Nicholas Thomford et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Crossing the blood-brain barrier with nanoparticles
- (2018) Yiqun Zhou et al. JOURNAL OF CONTROLLED RELEASE
- Human brain organoid-on-a-chip to model prenatal nicotine exposure
- (2018) Yaqing Wang et al. LAB ON A CHIP
- Recent advances in microfluidic technologies for cell-to-cell interaction studies
- (2018) Mario Rothbauer et al. LAB ON A CHIP
- Huntington's disease: Current and future therapeutic prospects
- (2018) Karl Kieburtz et al. MOVEMENT DISORDERS
- Disease Modification in Parkinson's Disease: Current Approaches, Challenges, and Future Considerations
- (2018) Anthony E. Lang et al. MOVEMENT DISORDERS
- A 3D human triculture system modeling neurodegeneration and neuroinflammation in Alzheimer’s disease
- (2018) Joseph Park et al. NATURE NEUROSCIENCE
- Overcoming the Blood-Brain Barrier: The Role of Nanomaterials in Treating Neurological Diseases
- (2018) Denzil Furtado et al. ADVANCED MATERIALS
- A filter-free blood-brain barrier model to quantitatively study transendothelial delivery of nanoparticles by fluorescence spectroscopy
- (2018) Edwin De Jong et al. JOURNAL OF CONTROLLED RELEASE
- Three-dimensional (3D) tetra-culture brain on chip platform for organophosphate toxicity screening
- (2018) Youngmi Koo et al. Scientific Reports
- Human iPSC-derived blood-brain barrier microvessels: validation of barrier function and endothelial cell behavior
- (2018) Raleigh M. Linville et al. BIOMATERIALS
- Blood–brain-barrier organoids for investigating the permeability of CNS therapeutics
- (2018) Sonja Bergmann et al. Nature Protocols
- 3D Cultures of Parkinson's Disease-Specific Dopaminergic Neurons for High Content Phenotyping and Drug Testing
- (2018) Silvia Bolognin et al. Advanced Science
- Microphysiological 3D model of amyotrophic lateral sclerosis (ALS) from human iPS-derived muscle cells and optogenetic motor neurons
- (2018) Tatsuya Osaki et al. Science Advances
- Neurovascular unit crosstalk: Pericytes and astrocytes modify cytokine secretion patterns of brain endothelial cells
- (2017) William A Banks et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- A facile approach to functionalizing cell membrane-coated nanoparticles with neurotoxin-derived peptide for brain-targeted drug delivery
- (2017) Zhilan Chai et al. JOURNAL OF CONTROLLED RELEASE
- Selective Electrochemical Detection of Dopamine Using Reduced Graphene Oxide Sheets-Gold Nanoparticles Modified Electrode
- (2017) Da-Jeong Park et al. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
- An isogenic blood-brain barrier model comprising brain endothelial cells, astrocytes, and neurons derived from human induced pluripotent stem cells
- (2017) Scott G. Canfield et al. JOURNAL OF NEUROCHEMISTRY
- A 3D neurovascular microfluidic model consisting of neurons, astrocytes and cerebral endothelial cells as a blood–brain barrier
- (2017) Giulia Adriani et al. LAB ON A CHIP
- Silver Nanoparticle Modified Electrode Covered by Graphene Oxide for the Enhanced Electrochemical Detection of Dopamine
- (2017) Jae-Wook Shin et al. SENSORS
- A 3D Real-Scale, Biomimetic, and Biohybrid Model of the Blood-Brain Barrier Fabricated through Two-Photon Lithography
- (2017) Attilio Marino et al. Small
- Microphysiological Human Brain and Neural Systems-on-a-Chip: Potential Alternatives to Small Animal Models and Emerging Platforms for Drug Discovery and Personalized Medicine
- (2017) Alexander P. Haring et al. Stem Cell Reviews and Reports
- Blood-brain-barrier spheroids as an in vitro screening platform for brain-penetrating agents
- (2017) Choi-Fong Cho et al. Nature Communications
- A microfluidic model of the blood–brain barrier to study permeabilization by pulsed electric fields
- (2017) M. Bonakdar et al. RSC Advances
- In Vitro Microfluidic Models for Neurodegenerative Disorders
- (2017) Tatsuya Osaki et al. Advanced Healthcare Materials
- Microphysiological Human Brain and Neural Systems-on-a-Chip: Potential Alternatives to Small Animal Models and Emerging Platforms for Drug Discovery and Personalized Medicine
- (2017) Alexander P. Haring et al. Stem Cell Reviews and Reports
- The Role of Astrocytes in Neuroprotection after Brain Stroke: Potential in Cell Therapy
- (2017) Andrea Becerra-Calixto et al. Frontiers in Molecular Neuroscience
- Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells
- (2017) Antje Appelt-Menzel et al. Stem Cell Reports
- Directed differentiation of human pluripotent stem cells to blood-brain barrier endothelial cells
- (2017) Tongcheng Qian et al. Science Advances
- Development of a blood-brain barrier model in a membrane-based microchip for characterization of drug permeability and cytotoxicity for drug screening
- (2016) Xiaojian Shao et al. ANALYTICA CHIMICA ACTA
- Microfluidic blood-brain barrier model provides in vivo-like barrier properties for drug permeability screening
- (2016) Ying I. Wang et al. BIOTECHNOLOGY AND BIOENGINEERING
- Nanoparticle-mediated brain drug delivery: Overcoming blood–brain barrier to treat neurodegenerative diseases
- (2016) Cláudia Saraiva et al. JOURNAL OF CONTROLLED RELEASE
- Role of neuroinflammation in neurodegenerative diseases (Review)
- (2016) WEI-WEI CHEN et al. Molecular Medicine Reports
- Organization of Endothelial Cells, Pericytes, and Astrocytes into a 3D Microfluidic in Vitro Model of the Blood–Brain Barrier
- (2016) Jack D. Wang et al. MOLECULAR PHARMACEUTICS
- How neuroinflammation contributes to neurodegeneration
- (2016) R. M. Ransohoff SCIENCE
- Microfluidic device for the formation of optically excitable, three-dimensional, compartmentalized motor units
- (2016) S. G. M. Uzel et al. Science Advances
- Distinct Contributions of Astrocytes and Pericytes to Neuroinflammation Identified in a 3D Human Blood-Brain Barrier on a Chip
- (2016) Anna Herland et al. PLoS One
- A dynamic in vivo-like organotypic blood-brain barrier model to probe metastatic brain tumors
- (2016) Hui Xu et al. Scientific Reports
- Large-Scale Nanoelectrode Arrays to Monitor the Dopaminergic Differentiation of Human Neural Stem Cells
- (2015) Tae-Hyung Kim et al. ADVANCED MATERIALS
- Collagen-based brain microvasculature model in vitro using three-dimensional printed template
- (2015) Jeong Ah Kim et al. Biomicrofluidics
- Recreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic bioreactor
- (2015) Jacquelyn A. Brown et al. Biomicrofluidics
- Three-dimensional brain-on-a-chip with an interstitial level of flow and its application as an in vitro model of Alzheimer's disease
- (2015) JiSoo Park et al. LAB ON A CHIP
- Three-Dimensional Blood-Brain Barrier Model for in vitro Studies of Neurovascular Pathology
- (2015) Hansang Cho et al. Scientific Reports
- A Novel Dynamic Neonatal Blood-Brain Barrier on a Chip
- (2015) Sudhir P. Deosarkar et al. PLoS One
- Permeability Analysis of Neuroactive Drugs Through a Dynamic Microfluidic In Vitro Blood–Brain Barrier Model
- (2014) R. Booth et al. ANNALS OF BIOMEDICAL ENGINEERING
- Bidirectional crosstalk between periventricular endothelial cells and neural progenitor cells promotes the formation of a neurovascular unit
- (2014) Ravi Vissapragada et al. BRAIN RESEARCH
- The Role of Pericytes in Neurovascular Unit Remodeling in Brain Disorders
- (2014) Ayman ElAli et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- In Vitro Modeling of the Neurovascular Environment by Coculturing Adult Human Brain Endothelial Cells with Human Neural Stem Cells
- (2014) Chung-Hsing Chou et al. PLoS One
- Diverse cellular and molecular modes of axon degeneration
- (2014) Lukas J. Neukomm et al. TRENDS IN CELL BIOLOGY
- Astrocytic laminin regulates pericyte differentiation and maintains blood brain barrier integrity
- (2014) Yao Yao et al. Nature Communications
- Reconstituting Vascular Microenvironment of Neural Stem Cell Niche in Three-Dimensional Extracellular Matrix
- (2014) Yoojin Shin et al. Advanced Healthcare Materials
- β-Amyloid is transmitted via neuronal connections along axonal membranes
- (2013) Ha-Lim Song et al. ANNALS OF NEUROLOGY
- Crosstalk between cerebral endothelium and oligodendrocyte
- (2013) Nobukazu Miyamoto et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Astrocyte–neuron co-culture on microchips based on the model of SOD mutation to mimic ALS
- (2013) Anja Kunze et al. Integrative Biology
- A Novel Brain Neurovascular Unit Model with Neurons, Astrocytes and Microvascular Endothelial Cells of Rat
- (2013) Qiang Xue et al. International Journal of Biological Sciences
- Microfluidic primary culture model of the lower motor neuron–neuromuscular junction circuit
- (2013) Katherine A. Southam et al. JOURNAL OF NEUROSCIENCE METHODS
- Advances in microfluidics-based experimental methods for neuroscience research
- (2013) Jae Woo Park et al. LAB ON A CHIP
- Microfluidic Chemotaxis Platform for Differentiating the Roles of Soluble and Bound Amyloid-β on Microglial Accumulation
- (2013) Hansang Cho et al. Scientific Reports
- Integrated Microfluidics Platforms for Investigating Injury and Regeneration of CNS Axons
- (2012) Hyung Joon Kim et al. ANNALS OF BIOMEDICAL ENGINEERING
- Characterization of a microfluidic in vitro model of the blood-brain barrier (μBBB)
- (2012) Ross Booth et al. LAB ON A CHIP
- SyM-BBB: a microfluidic blood brain barrier model
- (2012) Balabhaskar Prabhakarpandian et al. LAB ON A CHIP
- A modular approach to create a neurovascular unit-on-a-chip
- (2012) Anil Kumar H. Achyuta et al. LAB ON A CHIP
- Quantitative Targeted Absolute Proteomic Analysis of Transporters, Receptors and Junction Proteins for Validation of Human Cerebral Microvascular Endothelial Cell Line hCMEC/D3 as a Human Blood–Brain Barrier Model
- (2012) Sumio Ohtsuki et al. MOLECULAR PHARMACEUTICS
- Myelin basic protein induces inflammatory mediators from primary human endothelial cells and blood-brain barrier disruption: implications for the pathogenesis of multiple sclerosis
- (2012) T. G. D'Aversa et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- The neurovascular unit in brain function and disease
- (2011) C. Lecrux et al. Acta Physiologica
- Specific Role of Tight Junction Proteins Claudin-5, Occludin, and ZO-1 of the Blood–Brain Barrier in a Focal Cerebral Ischemic Insult
- (2011) Haixia Jiao et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Valve-based microfluidic compression platform: single axon injury and regrowth
- (2011) Suneil Hosmane et al. LAB ON A CHIP
- Transcriptomic and Quantitative Proteomic Analysis of Transporters and Drug Metabolizing Enzymes in Freshly Isolated Human Brain Microvessels
- (2011) Ramzi Shawahna et al. MOLECULAR PHARMACEUTICS
- Pericytes regulate the blood–brain barrier
- (2010) Annika Armulik et al. NATURE
- The benefits and limitations of animal models for translational research in neurodegenerative diseases
- (2010) Mathias Jucker NATURE MEDICINE
- Neurodegeneration and the neurovascular unit
- (2010) Berislav V Zlokovic NATURE MEDICINE
- Are animal models relevant to key aspects of human parturition?
- (2009) Bryan F. Mitchell et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- An in vivo biosensor for neurotransmitter release and in situ receptor activity
- (2009) Quoc-Thang Nguyen et al. NATURE NEUROSCIENCE
- The blood–brain barrier and immune function and dysfunction
- (2009) William A. Banks et al. NEUROBIOLOGY OF DISEASE
- Structure and function of the blood–brain barrier
- (2009) N. Joan Abbott et al. NEUROBIOLOGY OF DISEASE
- Are animal models predictive for humans?
- (2009) Niall Shanks et al. Philosophy Ethics and Humanities in Medicine
- The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
- (2008) Berislav V. Zlokovic NEURON
- Physical activity and risk of neurodegenerative disease: a systematic review of prospective evidence
- (2008) M. Hamer et al. PSYCHOLOGICAL MEDICINE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started