Permeability Analysis of Neuroactive Drugs Through a Dynamic Microfluidic In Vitro Blood–Brain Barrier Model

A multiple-channel, multiple-assay platform for characterization of full-range shear stress effects on vascular endothelial cells

(2014) R. Booth et al.   LAB ON A CHIP

Sunitinib LC–MS/MS Assay in Mouse Plasma and Brain Tissue: Application in CNS Distribution Studies

(2013) Rajneet K. Oberoi et al.   CHROMATOGRAPHIA

An automated method for the measurement of a range of tyrosine kinase inhibitors in human plasma or serum using turbulent flow liquid chromatography–tandem mass spectrometry

(2012) L. Couchman et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

BBB ON CHIP: microfluidic platform to mechanically and biochemically modulate blood-brain barrier function

(2012) L. M. Griep et al.   BIOMEDICAL MICRODEVICES

Characterization of a microfluidic in vitro model of the blood-brain barrier (μBBB)

(2012) Ross Booth et al.   LAB ON A CHIP

SyM-BBB: a microfluidic blood brain barrier model

(2012) Balabhaskar Prabhakarpandian et al.   LAB ON A CHIP

A modular approach to create a neurovascular unit-on-a-chip

(2012) Anil Kumar H. Achyuta et al.   LAB ON A CHIP

The role of shear stress in Blood-Brain Barrier endothelial physiology

(2011) Luca Cucullo et al.   BMC NEUROSCIENCE

Effect of Surface Charge of Immortalized Mouse Cerebral Endothelial Cell Monolayer on Transport of Charged Solutes

(2010) Wei Yuan et al.   ANNALS OF BIOMEDICAL ENGINEERING

Permeability of Endothelial and Astrocyte Cocultures: In Vitro Blood–Brain Barrier Models for Drug Delivery Studies

(2010) Guanglei Li et al.   ANNALS OF BIOMEDICAL ENGINEERING

Pre-clinical properties of the α4β2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence

(2010) H Rollema et al.   BRITISH JOURNAL OF PHARMACOLOGY

Irreversible, direct bonding of nanoporous polymer membranes to PDMS or glass microdevices

(2010) Kiana Aran et al.   LAB ON A CHIP

Addressing Central Nervous System (CNS) Penetration in Drug Discovery: Basics and Implications of the Evolving New Concept

(2009) Andreas Reichel   CHEMISTRY & BIODIVERSITY

Studying the Neurovascular Unit: An Improved Blood–Brain Barrier Model

(2009) Christoph M Zehendner et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

P2-375: Efficacy of the novel γ-secretase inhibitor, PF-3084014, in reducing Aβ in brain, CSF, and plasma in guinea pigs and Tg2576 mice

(2008) Kathleen M. Wood et al.   Alzheimers & Dementia

Brain endothelial cells and the glio-vascular complex

(2008) Hartwig Wolburg et al.   CELL AND TISSUE RESEARCH

Validation of in vitro cell culture models of the blood–brain barrier: Tightness characterization of two promising cell lines

(2008) Winfried Neuhaus et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

A new blood–brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes

(2008) Shinsuke Nakagawa et al.   NEUROCHEMISTRY INTERNATIONAL

QSAR Modeling of the Blood–Brain Barrier Permeability for Diverse Organic Compounds

(2008) Liying Zhang et al.   PHARMACEUTICAL RESEARCH

Toward an improved prediction of humanin vivobrain penetration

(2008) S. G. Summerfield et al.   XENOBIOTICA