Xanthones and Cancer: from Natural Sources to Mechanisms of Action

All that glitters is not gold: Panning cytotoxic natural products and derivatives with a fused tricyclic backbone by the estimation of their leadlikeness for cancer treatment

(2019) Luiz Carlos Klein et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Carboxyxanthones: Bioactive Agents and Molecular Scaffold for Synthesis of Analogues and Derivatives

(2019) João Ribeiro et al.   MOLECULES

Cytotoxic Prenylated Xanthones from the Leaves of Garcinia bracteata

(2019) Bao-Jun Zhang et al.   PLANTA MEDICA

Garcixanthone D, a New Xanthone, and Other Xanthone Derivatives From Garcinia mangostana Pericarps: Their α‐Amylase Inhibitory Potential and Molecular Docking Studies

(2019) Sabrin Ragab Mohamed Ibrahim et al.   STARCH-STARKE

Mangostanaxanthone VIIII, a new xanthone from Garcinia mangostana pericarps, α-amylase inhibitory activity, and molecular docking studies

(2019) Sabrin R.M. Ibrahim et al.   Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy

Synthesis, structure-activity relationship and in vitro pharmacodynamics of A-ring modified caged xanthones in a preclinical model of inflammatory breast cancer

(2019) Oraphin Chantarasriwong et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design and synthesis of novel xanthone-triazole derivatives as potential antidiabetic agents: α-Glucosidase inhibition and glucose uptake promotion

(2019) Gao-Jie Ye et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Tetrandraxanthones A–I, Prenylated and Geranylated Xanthones from the Stem Bark of Garcinia tetrandra

(2019) Edwin Risky Sukandar et al.   JOURNAL OF NATURAL PRODUCTS

Synthesis, Biological Evaluation, and In Silico Studies of Novel Aminated Xanthones as Potential p53-Activating Agents

(2019) Lemos et al.   MOLECULES

Gambogic acid impairs tumor angiogenesis by targeting YAP/STAT3 signaling axis

(2019) Li Wan et al.   PHYTOTHERAPY RESEARCH

A tocotrienol quinone dimer and xanthones from the leaf extract of Garcinia nigrolineata

(2019) Achara Raksat et al.   FITOTERAPIA

Cytotoxic phenolic constituents from Hypericum japonicum

(2019) Wei Zhu et al.   PHYTOCHEMISTRY

Xanthones from the stems of Cudrania tricuspidata and their inhibitory effects on pancreatic lipase and fat accumulation

(2019) Yang Hee Jo et al.   BIOORGANIC CHEMISTRY

Xanthone derivatives from the leaves of Garcinia oligantha

(2019) Yue-Xun Tang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Antitumor and anti-nematode activities of α-mangostin

(2019) Joanna Markowicz et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Gambogic acid exhibits anti-metastatic activity on malignant melanoma mainly through inhibition of PI3K/Akt and ERK signaling pathways

(2019) Chun-yu Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Two new coumarins and a new xanthone from the leaves of Rhizophora mucronata

(2018) Kaori Taniguchi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Promiscuous enzyme-catalyzed cascade reaction: Synthesis of xanthone derivatives

(2018) Yajie Fu et al.   BIOORGANIC CHEMISTRY

Plants as sources of natural and recombinant anti-cancer agents

(2018) J.F. Buyel   BIOTECHNOLOGY ADVANCES

Bioactivity and pharmacological properties of α-mangostin from the mangosteen fruit: a review

(2018) Guoqing Chen et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Garcixanthone A, a new cytotoxic xanthone from the pericarps of Garcinia mangostana

(2018) Sabrin Ragab Mohamed Ibrahim et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Bioassay- and Chemistry-Guided Isolation of Scalemic Caged Prenylxanthones from the Leaves of Garcinia bracteata

(2018) Sheng-Li Niu et al.   JOURNAL OF NATURAL PRODUCTS

Mangostanaxanthone VIII, a new xanthone from Garcinia mangostana and its cytotoxic activity

(2018) Sabrin R. M. Ibrahim et al.   NATURAL PRODUCT RESEARCH

Garcixanthones B and C, new xanthones from the pericarps of Garcinia mangostana and their cytotoxic activity

(2018) Sabrin R.M. Ibrahim et al.   Phytochemistry Letters

Piperidine alkaloids and xanthone from the roots of Caulophyllum robustum Maxim

(2018) Hui-Xiang Yang et al.   FITOTERAPIA

Xanthones and biphenyls from the stems of Garcinia cylindrocarpa and their cytotoxicity

(2018) Edwin Risky Sukandar et al.   FITOTERAPIA

Anti-HIV and cytotoxic biphenyls, benzophenones and xanthones from stems, leaves and twigs of Garcinia speciosa

(2018) Phanruethai Pailee et al.   PHYTOCHEMISTRY

A novel entry to xanthones by an intramolecular Diels-Alder reaction involving 2-(1,2-dichlorovinyloxy) aryl dienones

(2018) Katerina Otrubova et al.   TETRAHEDRON

A new xanthone glycoside from Pyrrosia sheareri

(2018) Kang He et al.   NATURAL PRODUCT RESEARCH

Cytotoxic xanthones from the roots of Mesua ferrea L.

(2018) Arnon Chukaew et al.   PHYTOCHEMISTRY

Two xanthones and two rotameric (3⟶8) biflavonoids from the Cameroonian medicinal plant Allanblackia floribunda Oliv. (Guttiferae)

(2018) Bel Youssouf G. Mountessou et al.   TETRAHEDRON LETTERS

Bioactive scalemic caged xanthones from the leaves of Garcinia bracteata

(2018) Bao-Jun Zhang et al.   BIOORGANIC CHEMISTRY

Synthesis of xanthone derivatives and studies on the inhibition against cancer cells growth and synergistic combinations of them

(2017) Jie Liu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Xanthones from the twigs of Garcinia oblongifolia and their antidiabetic activity

(2017) Binh T.D. Trinh et al.   FITOTERAPIA

New xanthones and cytotoxic constituents from Garcinia mangostana fruit hulls against human hepatocellular, breast, and colorectal cancer cell lines

(2017) Gamal A. Mohamed et al.   JOURNAL OF ETHNOPHARMACOLOGY

Symmetrically Substituted Xanthone Amphiphiles Combat Gram-Positive Bacterial Resistance with Enhanced Membrane Selectivity

(2017) Shuimu Lin et al.   JOURNAL OF MEDICINAL CHEMISTRY

Prenylated xanthones from the stem bark of Garcinia dulcis

(2017) Parichat Thepthong et al.   Phytochemistry Letters

UNC119 mediates gambogic acid-induced cell-cycle dysregulation through the Gsk3β/β-catenin pathway in hepatocellular carcinoma cells

(2016) Lili Wu et al.   ANTI-CANCER DRUGS

The potential role of mangiferin in cancer treatment through its immunomodulatory, anti-angiogenic, apoptopic, and gene regulatory effects

(2016) Alberto J. Núñez Selles et al.   BIOFACTORS

Structure–activity relationship of Garcinia xanthones analogues: Potent Hsp90 inhibitors with cytotoxicity and antiangiogenesis activity

(2016) Xiaoli Xu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Caged xanthones: Potent inhibitors of global predominant MRSA USA300

(2016) Pongkorn Chaiyakunvat et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, synthesis, and anticonvulsant activity of some derivatives of xanthone with aminoalkanol moieties

(2016) Anna M. Waszkielewicz et al.   Chemical Biology & Drug Design

The Design, Synthesis, and Evaluation of 1,5,7-Trisubstituted-3-Pyridyl-Xanthones for Use as Insecticides Starting from Pyripyropene A

(2016) Shinichiro Fuse et al.   CHEMISTRY-A EUROPEAN JOURNAL

Recent developments in the pharmacology of prenylated xanthones

(2016) Salvatore Genovese et al.   DRUG DISCOVERY TODAY

Recent insight into the biological activities of synthetic xanthone derivatives

(2016) Shagufta et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Amphiphilic xanthones as a potent chemical entity of anti-mycobacterial agents with membrane-targeting properties

(2016) Jun-Jie Koh et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

RXRα transcriptional inhibitors from the stems of Calophyllum membranaceum

(2016) Meng Ming et al.   FITOTERAPIA

Cylindroxanthones A–C, three new xanthones and their cytotoxicity from the stem bark of Garcinia cylindrocarpa

(2016) Edwin Risky Sukandar et al.   FITOTERAPIA

Bioactive gentixanthone and gentichromone from the whole plants of Gentianella acuta (Michx.) Hulten

(2016) Yanxia Liu et al.   FITOTERAPIA

New depsidones and xanthone from the roots of Garcinia schomburgkiana

(2016) Edwin Risky Sukandar et al.   FITOTERAPIA

Antitumor and apoptosis-inducing effects of α-mangostin extracted from the pericarp of the mangosteen fruit (Garcinia mangostana L.) in YD-15 tongue mucoepidermoid carcinoma cells

(2016) HAE NIM LEE et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Antiproliferative and apoptosis induction of α-mangostin in T47D breast cancer cells

(2016) SOMCHAI KRITSANAWONG et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

New Benzophenones and Xanthones from Cratoxylum sumatranum ssp. neriifolium and Their Antibacterial and Antioxidant Activities

(2016) Cholpisut Tantapakul et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Antioxidant compounds from the stem bark ofGarcinia atroviridis

(2016) Wen-Nee Tan et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Tetrahydroxanthones from Mongolian medicinal plant Gentianella amarella ssp. acuta

(2016) Shuangxin Lu et al.   Journal of Natural Medicines

Chemical Constituents Isolated from the Root Bark of Cudrania tricuspidata and Their Potential Neuroprotective Effects

(2016) Jaeyoung Kwon et al.   JOURNAL OF NATURAL PRODUCTS

Bioassay-Guided Isolation of Prenylated Xanthone Derivatives from the Leaves of Garcinia oligantha

(2016) Yue-Xun Tang et al.   JOURNAL OF NATURAL PRODUCTS

Polyprenylated Tetraoxygenated Xanthones from the Roots of Hypericum monogynum and Their Neuroprotective Activities

(2016) Wen-Jun Xu et al.   JOURNAL OF NATURAL PRODUCTS

Xanthones from the green branch ofGarcinia dulcis

(2016) Wilawan Mahabusarakam et al.   NATURAL PRODUCT RESEARCH

Synergic Effect ofα-Mangostin on the Cytotoxicity of Cisplatin in a Cervical Cancer Model

(2016) Jazmin M. Pérez-Rojas et al.   Oxidative Medicine and Cellular Longevity

Nitric oxide inhibitory xanthones from the pericarps of Garcinia mangostana

(2016) Qianyu Liu et al.   PHYTOCHEMISTRY

Cytotoxic prenylated xanthone and coumarin derivatives from Malaysian Mesua beccariana

(2016) Thiruventhan Karunakaran et al.   Phytochemistry Letters

FeCl3-Catalyzed Three-Component One-Pot Synthesis of Novel 4-[(Benzo[d]thiazol-2-ylamino)(phenyl)methyl]-3-hydroxy-9H-xanthen-9-ones

(2016) Babu Priya et al.   SYNLETT

Selective Preparation of Xanthones from 2-Bromofluorobenzenes and Salicylaldehydes via Palladium-Catalyzed Acylation–SNAr Approach

(2016) Xiao-Feng Wu et al.   SYNLETT

An Efficient Isoprenylation of Xanthones at the C1 Position by Utilizing Anion-Accelerated Aromatic Oxy-Cope Rearrangement

(2016) Takashi Matsumoto et al.   SYNLETT

Molecular targets of gambogic acid in cancer: recent trends and advancements

(2016) Dharambir Kashyap et al.   TUMOR BIOLOGY

Gambogic acid inhibits the growth of ovarian cancer tumors by regulating p65 activity

(2016) Qiusha Tang et al.   Oncology Letters

α-Mangostin from Garcinia mangostana Linn: An updated review of its pharmacological properties

(2016) Mohamed Yousif Ibrahim et al.   Arabian Journal of Chemistry

Mangiferin and Cancer: Mechanisms of Action

(2016) Fuchsia Gold-Smith et al.   Nutrients

Dietary phytochemicals and cancer chemoprevention: a review of the clinical evidence

(2016) Ritesh Kotecha et al.   Oncotarget

UPLC-PDA-QTOFMS-guided isolation of prenylated xanthones and benzoylphloroglucinols from the leaves of Garcinia oblongifolia and their migration-inhibitory activity

(2016) Hong Zhang et al.   Scientific Reports

Probing the Catalytic Promiscuity of a Regio- and Stereospecific C-Glycosyltransferase fromMangifera indica

(2015) Dawei Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Xanthones from Garcinia paucinervis with in vitro anti-proliferative activity against HL-60 cells

(2015) Da-Hong Li et al.   ARCHIVES OF PHARMACAL RESEARCH

Kaennacowanols A–C, three new xanthones and their cytotoxicity from the roots of Garcinia cowa

(2015) Sutin Kaennakam et al.   FITOTERAPIA

Synthesis and antitumor activity evaluation of a novel series of xanthone derivatives

(2015) Na Guo et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Venuloxanthone, a new pyranoxanthone from the stem bark ofCalophyllum venulosum

(2015) Ahmad Azri Fitri bin Ismail et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Bioactive prenylated xanthones from the stems ofCratoxylum cochinchinense

(2015) Ying-Hui Duan et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Three new xanthones from the leaves of Garcinia lancilimba

(2015) Yating Sun et al.   Journal of Natural Medicines

Regioselective Tandem [4 + 1]–[4 + 2] Synthesis of Amino-Substituted Dihydroxanthones and Xanthones

(2015) Ana Bornadiego et al.   JOURNAL OF ORGANIC CHEMISTRY

Syntheses of Dimeric Tetrahydroxanthones with Varied Linkages: Investigation of “Shapeshifting” Properties

(2015) Tian Qin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular Cloning and Characterization of a Xanthone Prenyltransferase from Hypericum calycinum Cell Cultures

(2015) Tobias Fiesel et al.   MOLECULES

Xanthones from the herb ofSwertia elataand their anti-TMV activity

(2015) Wei Jiang et al.   NATURAL PRODUCT RESEARCH

Anti-inflammatory activity of benzophenone and xanthone derivatives isolated from Garcinia (Clusiaceae) species

(2015) Jean Paul Dzoyem et al.   Phytochemistry Letters

Antibacterial and Antioxidant Xanthones and Benzophenone from Garcinia smeathmannii

(2015) Hugues Fouotsa et al.   PLANTA MEDICA

New strategies for the synthesis and functionalization of tetrahydroxanthones

(2015) Penelope A. Turner et al.   TETRAHEDRON

Microwave-assisted synthesis of xanthones promoted by ytterbium triflate

(2015) Salvatore Genovese et al.   TETRAHEDRON LETTERS

Synthesis and antibacterial evaluation of novel xanthone sulfonamides

(2015) Mina Malekpoor et al.   JOURNAL OF CHEMICAL RESEARCH

Synthesis and bioactivity of novel xanthone and thioxanthone l-rhamnopyranosides

(2015) Gao-peng Song et al.   RSC Advances

Synthesis of 4-Aminoxanthones by an Uncatalyzed, Multicomponent Reaction

(2014) Ana Bornadiego et al.   ADVANCED SYNTHESIS & CATALYSIS

Benzophenone C-glucosides and gallotannins from mango tree stem bark with broad-spectrum anti-viral activity

(2014) Wael M. Abdel-Mageed et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Cytotoxic Compounds from the Leaves ofGarcinia polyantha

(2014) Alain Meli Lannang et al.   CHEMISTRY & BIODIVERSITY

Mangostanaxanthones I and II, new xanthones from the pericarp of Garcinia mangostana

(2014) Gamal A. Mohamed et al.   FITOTERAPIA

Antibacterial tetraoxygenated xanthones from the immature fruits of Garcinia cowa

(2014) Chiramet Auranwiwat et al.   FITOTERAPIA

Anti-ulcer xanthones from the roots of Hypericum oblongifolium Wall

(2014) Mumtaz Ali et al.   FITOTERAPIA

New Isoprenylated Xanthones fromCudrania tricuspidata

(2014) Chun Lei et al.   HELVETICA CHIMICA ACTA

New constituents from the roots of Oenothera biennis and their free radical scavenging and ferric reducing activity

(2014) Ateeque Ahmad et al.   INDUSTRIAL CROPS AND PRODUCTS

A new furanoxanthone fromGarcinia mangostana

(2014) Gwendoline Cheng Lian Ee et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Two xanthones from Swertia punicea with hepatoprotective activities in vitro and in vivo

(2014) Xi-Yuan Zheng et al.   JOURNAL OF ETHNOPHARMACOLOGY

Amino Acid Modified Xanthone Derivatives: Novel, Highly Promising Membrane-Active Antimicrobials for Multidrug-Resistant Gram-Positive Bacterial Infections

(2014) Jun-Jie Koh et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cytotoxic and Anti-Inflammatory Prenylated Benzoylphloroglucinols and Xanthones from the Twigs of Garcinia esculenta

(2014) Hong Zhang et al.   JOURNAL OF NATURAL PRODUCTS

Three Types of Cytotoxic Natural Caged-Scaffolds: Pure Enantiomers or Partial Racemates

(2014) Nawong Boonnak et al.   JOURNAL OF NATURAL PRODUCTS

Antiproliferative Prenylated Xanthones and Benzophenones from the Roots of Cudrania tricuspidata in HSC-T6 Cells

(2014) Yang Hee Jo et al.   JOURNAL OF NATURAL PRODUCTS

Neuroprotective Xanthones from the Root Bark of Cudrania tricuspidata

(2014) Jaeyoung Kwon et al.   JOURNAL OF NATURAL PRODUCTS

Muchimangins G–J, Fully Substituted Xanthones with a Diphenylmethyl Substituent, from Securidaca longepedunculata

(2014) Dya F. Dibwe et al.   JOURNAL OF NATURAL PRODUCTS

Ru(II)-Catalyzed Selective C–H Amination of Xanthones and Chromones with Sulfonyl Azides: Synthesis and Anticancer Evaluation

(2014) Youngmi Shin et al.   JOURNAL OF ORGANIC CHEMISTRY

A Green and Regioselsctive Synthesis of Xanthone and Thioxanthone Derivatives in the Presence of Heteropoly Acid Under Microwave Irradiation

(2014) Mohammad Nasseri et al.   LETTERS IN ORGANIC CHEMISTRY

Xanthones with anti-tumor activity isolated from Securidaca inappendiculata

(2014) Jian Zuo et al.   MEDICINAL CHEMISTRY RESEARCH

Anti-angiogenic actions of the mangosteen polyphenolic xanthone derivative α-mangostin

(2014) Kanjana Jittiporn et al.   MICROVASCULAR RESEARCH

Cytotoxic Prenylated Xanthones from the Pericarps of Garcinia mangostana

(2014) Zeng Xu et al.   MOLECULES

A New Xanthone from Moutabea guianensis Aubl

(2014) Haroldo da S. Ripardo Filho et al.   MOLECULES

Two New Chemical Constituents from the Stem Bark of Garcinia mangostana

(2014) Irene See et al.   MOLECULES

Xanthones from the Roots of Moutabea guianensis Aubl.

(2014) Haroldo Filho et al.   MOLECULES

A xanthone and a phenylanthraquinone from the roots of Bulbine frutescens, and the revision of six seco-anthraquinones into xanthones

(2014) Negera Abdissa et al.   Phytochemistry Letters

Cancer chemopreventive pharmacology of phytochemicals derived from plants of dietary and non-dietary origin: implication for alternative and complementary approaches

(2014) Mohammad F. Ullah et al.   PHYTOCHEMISTRY REVIEWS

Xanthine Oxidase Inhibitors from Garcinia esculenta Twigs

(2014) Lun-Lun Zhu et al.   PLANTA MEDICA

Xanthone Glycosides from Swertia bimaculata with α-Glucosidase Inhibitory Activity

(2014) Yao-Dong Yue et al.   PLANTA MEDICA

Synthesis of toxyloxanthone B

(2014) Daniele Giallombardo et al.   TETRAHEDRON

Microwave-assisted transition-metal-free intramolecular Ullmann-type O-arylation in water for the synthesis of xanthones and azaxanthones

(2014) Xiaojin Zhang et al.   TETRAHEDRON LETTERS

Regioselective synthesis of multiply halogenated azaxanthones

(2014) Wenyuan Qian et al.   TETRAHEDRON LETTERS

Muchimangins E and F: novel diphenylmethyl-substituted xanthones from Securidaca longepedunculata

(2014) Dya Fita Dibwe et al.   TETRAHEDRON LETTERS

Oxygenated xanthones and biflavanoids from the twigs of Garcinia xanthochymus

(2014) Kongkiat Trisuwan et al.   TETRAHEDRON LETTERS

Anti-Helicobacter pylori xanthones of Garcinia fusca

(2013) Jannarin Nontakham et al.   ARCHIVES OF PHARMACAL RESEARCH

Heptaoxygenated xanthones as anti-austerity agents from Securidaca longepedunculata

(2013) Dya Fita Dibwe et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and biological evaluation of 1, 3-dihydroxyxanthone mannich base derivatives as anticholinesterase agents

(2013) Jiangke Qin et al.   Chemistry Central Journal

Pyranoxanthones: Synthesis, growth inhibitory activity on human tumor cell lines and determination of their lipophilicity in two membrane models

(2013) Carlos M.G. Azevedo et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Antioxidant xanthones from Swertia mussotii , a high altitude plant

(2013) Cui-Ting Luo et al.   FITOTERAPIA

Glomexanthones A–C, three xanthonolignoid C-glycosides from Polygala glomerata Lour

(2013) Chuang-Jun Li et al.   FITOTERAPIA

A Novel Xanthone fromGarcinia oligantha

(2013) Xue-Mei Gao et al.   HELVETICA CHIMICA ACTA

New Xanthones from Garcinia bracteata and Their Cytotoxicities

(2013) Qiufen Hu et al.   HETEROCYCLES

Xanthone Glycoside Constituents of Swertia kouitchensis with α-Glucosidase Inhibitory Activity

(2013) Luo-Sheng Wan et al.   JOURNAL OF NATURAL PRODUCTS

Antitumour and free radical scavenging effects of γ-mangostin isolated fromGarcinia mangostanapericarps against hepatocellular carcinoma cell

(2013) Hui-Fang Chang et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Structure elucidation and NMR assignments of two unusual xanthones fromLomatogonium carinthiacum(Wulf) Reichb

(2013) Qinghu Wang et al.   MAGNETIC RESONANCE IN CHEMISTRY

Design, synthesis, and in vitro antibacterial screening of some novel 3-pentyloxy-1-hydroxyxanthone derivatives

(2013) Aparoop Das et al.   MEDICINAL CHEMISTRY RESEARCH

Three Novel Xanthones from Garcinia paucinervis and Their Anti-TMV Activity

(2013) Yu-Ping Wu et al.   MOLECULES

A new bixanthone derivative from the bark ofGarcinia oblongifolia

(2013) Shixiu Feng et al.   NATURAL PRODUCT RESEARCH

Xanthone and lignan glycosides from the aerial parts of Polygonum bellardii all growing in Egypt

(2013) AlaaM Nafady et al.   Pharmacognosy Magazine

COX-2 inhibitory activity of homoisoflavanones and xanthones from the bulbs of the Southern African Ledebouria socialis and Ledebouria ovatifolia (Hyacinthaceae: Hyacinthoideae)

(2013) Catherine P. Waller et al.   PHYTOCHEMISTRY

A prenylated xanthone and antiproliferative compounds from leaves of Pentadesma butyracea

(2013) Michel Feussi Tala et al.   Phytochemistry Letters

Tetraoxygenated xanthones and biflavanoids from the twigs of Garcinia merguensis

(2013) Kongkiat Trisuwan et al.   Phytochemistry Letters

Three new xanthones from the stems of Garcinia oligantha and their anti-TMV activity

(2013) Yu-Ping Wu et al.   Phytochemistry Letters

Three New Xanthones from the Resin of Garcinia hanburyi

(2013) Yun-Xia Deng et al.   PLANTA MEDICA

Inhibitory Activity of Chemical Constituents from Arenaria serpyllifolia on Nitric Oxide Production

(2013) Guan-Shen Zhou et al.   PLANTA MEDICA

Xanthones with Anti-Hepatitis B Virus Activity from Swertia mussotii

(2013) Tuan-Wu Cao et al.   PLANTA MEDICA

Swerpunilactones A and B, the first example of xanthone and secoiridoid heterodimers from Swertia punicea, S. hispidicalyx, and S. yunnanensis

(2013) Hong-Ling Wang et al.   TETRAHEDRON LETTERS

Mangiferin exerts antitumor activity in breast cancer cells by regulating matrix metalloproteinases, epithelial to mesenchymal transition, and β-catenin signaling pathway

(2013) Hongzhong Li et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Biological Activities and Bioavailability of Mangosteen Xanthones: A Critical Review of the Current Evidence

(2013) Fabiola Gutierrez-Orozco et al.   Nutrients

Gambogic Acid is a Novel Anti-cancer Agent that Inhibits Cell Proliferation, Angiogenesis and Metastasis

(2012) Xu Wang et al.   Anti-Cancer Agents in Medicinal Chemistry

Synthesis and in vitro antitumor activities of xanthone derivatives containing 1,4-disubstituted-1,2,3-triazole moiety

(2012) Yan Zou et al.   ARCHIVES OF PHARMACAL RESEARCH

Identification and evaluation of apoptotic compounds from Garcinia oligantha

(2012) Xue-Mei Gao et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Xanthones from Fungi, Lichens, and Bacteria: The Natural Products and Their Synthesis

(2012) Kye-Simeon Masters et al.   CHEMICAL REVIEWS

Bioassay-guided studies on Bombax ceiba leaf extract: isolation of shamimoside, a new antioxidant xanthone C-glucoside

(2012) Shaheen Faizi et al.   CHEMISTRY OF NATURAL COMPOUNDS

Routes to Xanthones: An Update on the Synthetic Approaches

(2012) Carlos Azevedo et al.   CURRENT ORGANIC CHEMISTRY

Cytotoxic alkoxylated xanthones from the resin of Garcinia hanburyi

(2012) Yun-Xia Deng et al.   FITOTERAPIA

Antibacterial dihydrobenzopyran and xanthone derivatives from Garcinia cowa stem barks

(2012) Ittipon Siridechakorn et al.   FITOTERAPIA

Polyprenylated Xanthones and Benzophenones from the Bark of Garcinia oblongifolia

(2012) Wei-Guang Shan et al.   HELVETICA CHIMICA ACTA

Two new xanthones fromSwertia angustifolia

(2012) Bao-Kun Zhu et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Bioassay-Guided Isolation of Prenylated Xanthones and Polycyclic Acylphloroglucinols from the Leaves of Garcinia nujiangensis

(2012) Zheng-Xiang Xia et al.   JOURNAL OF NATURAL PRODUCTS

Bioassay-Guided Investigation of the Tanzanian Plant Pyrenacantha kaurabassana for Potential Anti-HIV-Active Compounds

(2012) Justin J. Omolo et al.   JOURNAL OF NATURAL PRODUCTS

Rearranged Benzophenones and Prenylated Xanthones from Garcinia propinqua Twigs

(2012) Cholpisut Tantapakul et al.   JOURNAL OF NATURAL PRODUCTS

A New Furanoxanthone from the Root Bark of Mesua ferrea

(2012) Gwendoline C. L. Ee et al.   LETTERS IN ORGANIC CHEMISTRY

Xanthones from the stems of Cratoxylum cochinchinense

(2012) Yinghui Duan et al.   MAGNETIC RESONANCE IN CHEMISTRY

Phylattrin, a New Cytotoxic Xanthone from Calophyllum soulattri

(2012) Siau Hui Mah et al.   MOLECULES

Gamma-Mangostin, a Micronutrient of Mangosteen Fruit, Induces Apoptosis in Human Colon Cancer Cells

(2012) Hui-Fang Chang et al.   MOLECULES

A new xanthone from the bark ofCalophyllum thorelii

(2012) Le-Thu Thi Nguyen et al.   NATURAL PRODUCT RESEARCH

Alpha-mangostin suppresses MMP-2 and MMP-9 expression in head and neck squamous carcinoma cells

(2012) Ruchadaporn Kaomongkolgit   Odontology

Synthesis and evaluation of novel aza-caged Garcinia xanthones

(2012) Xiaojin Zhang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Direct Synthesis of Functional Azaxanthones by Using a Domino Three-Component Reaction

(2012) Jianwei Yan et al.   ORGANIC LETTERS

Xanthones from the stem bark of Garcinia bracteata with growth inhibitory effects against HL-60 cells

(2012) Sheng-Li Niu et al.   PHYTOCHEMISTRY

Benzophenones and xanthones from Garcinia cantleyana var. cantleyana and their inhibitory activities on human low-density lipoprotein oxidation and platelet aggregation

(2012) Ibrahim Jantan et al.   PHYTOCHEMISTRY

Friedolanostanes and xanthones from the twigs of Garcinia hombroniana

(2012) Saranyoo Klaiklay et al.   PHYTOCHEMISTRY

Cytotoxic tetraoxygenated xanthones from the bark of Garcinia schomburgkiana

(2012) Hau T. Vo et al.   Phytochemistry Letters

Xanthones from the bark of Garcinia pedunculata

(2012) Hau T. Vo et al.   Phytochemistry Letters

Xanthones inhibitors of α-glucosidase and glycation from Garcinia nobilis

(2012) Hugues Fouotsa et al.   Phytochemistry Letters

New Xanthone Glycosides from Comastoma pedunculatum

(2012) Yongqi Qiao et al.   PLANTA MEDICA

Microwave-Assisted Efficient and Green Synthesis of Hydroxyxanthone in Water

(2012) Xiao-Jin Zhang et al.   SYNTHETIC COMMUNICATIONS

Alternative simple and effective synthesis of (di)benzoxanthones and their functions toward fluorescent dyes

(2012) Eriko Azuma et al.   TETRAHEDRON

Polyisoprenylated acylphloroglucinols and a polyisoprenylated tetracyclic xanthone from the bark of Calophyllum thorelii

(2012) Le-Thu T. Nguyen et al.   TETRAHEDRON LETTERS

Palladium-catalyzed cascade reactions of 3-iodochromones with aryl iodides and norbornadiene leading to annulated xanthones

(2012) Ming Cheng et al.   Chemical Science

Mangiferin induces apoptosis by suppressing Bcl-xL and XIAP expressions and nuclear entry of NF-κB in HL-60 cells

(2011) Kaori Shoji et al.   ARCHIVES OF PHARMACAL RESEARCH

α-Mangostin extracted from the pericarp of the mangosteen (Garcinia mangostanaLinn) reduces tumor growth and lymph node metastasis in an immunocompetent xenograft model of metastatic mammary cancer carrying a p53 mutation

(2011) Masa-Aki Shibata et al.   BMC Medicine

 -Mangostin, a xanthone from mangosteen fruit, promotes cell cycle arrest in prostate cancer and decreases xenograft tumor growth

(2011) J. J. Johnson et al.   CARCINOGENESIS

α-Mangostin, a Dietary Xanthone, Induces Autophagic Cell Death by Activating the AMP-Activated Protein Kinase Pathway in Glioblastoma Cells

(2011) A-Ching Chao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Antiproliferative Activity of Xanthones Isolated fromArtocarpus obtusus

(2011) Najihah Mohd Hashim et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Synthesis of novel benzoxanthone analogues as non-Camptothecin topoisomerase I inhibitors

(2011) Pengfei Cheng et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Synthesis of Fluorinated Benzophenones, Xanthones, Acridones, and Thioxanthones by Iterative Nucleophilic Aromatic Substitution

(2011) Zachary R. Woydziak et al.   JOURNAL OF ORGANIC CHEMISTRY

A new xanthone fromGarcinia nitida

(2011) G.C.L. Ee et al.   NATURAL PRODUCT RESEARCH

A xanthone glycoside from aerial parts of Swertia paniculata

(2011) Neerja Pant et al.   Journal of Saudi Chemical Society

Recent Insights into the Biosynthesis and Biological Activities of Natural Xanthones

(2010) H. El-Seedi et al.   CURRENT MEDICINAL CHEMISTRY

Recent cancer drug development with xanthone structures

(2010) Younghwa Na   JOURNAL OF PHARMACY AND PHARMACOLOGY

Xanthones from the stems of Cratoxylum cochinchinense

(2010) Sutee Udomchotphruet et al.   PHYTOCHEMISTRY

Gambogic acid down-regulates MDM2 oncogene and induces p21Waf1/CIP1 expression independent of p53

(2009) Jing-Jing Rong et al.   CANCER LETTERS

Naturally Occurring Xanthones; Latest Investigations: Isolation, Structure Elucidation and Chemosystematic Significance

(2009) Hesham El-Seedi et al.   CURRENT MEDICINAL CHEMISTRY

Synthesis of Prenylated Xanthones: An Overview

(2009) M. Pinto et al.   CURRENT ORGANIC CHEMISTRY

Prenylation of aromatic compounds, a key diversification of plant secondary metabolites

(2009) Kazufumi Yazaki et al.   PHYTOCHEMISTRY

Gambogic acid mediates apoptosis as a p53 inducer through down-regulation of mdm2 in wild-type p53-expressing cancer cells

(2008) Hongyan Gu et al.   MOLECULAR CANCER THERAPEUTICS