Biological Activities and Bioavailability of Mangosteen Xanthones: A Critical Review of the Current Evidence

α-Mangostin: Anti-Inflammatory Activity and Metabolism by Human Cells

(2013) Fabiola Gutierrez-Orozco et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

α-Mangostin Reduced ER Stress-mediated Tumor Growth through Autophagy Activation

(2013) Sung-Jin Kim et al.   Immune Network

In vitro and in vivo anti-colon cancer effects of Garcinia mangostana xanthones extract

(2012) Abdalrahim F A Aisha et al.   BMC Complementary and Alternative Medicine

Single Dose Oral Pharmacokinetic Profile of α-Mangostin in Mice

(2012) Atulkumar Ramaiya et al.   CURRENT DRUG TARGETS

Mangosteen xanthones mitigate ovalbumin-induced airway inflammation in a mouse model of asthma

(2012) Ha-Young Jang et al.   FOOD AND CHEMICAL TOXICOLOGY

Alterations in Cell Cycle and Induction of Apoptotic Cell Death in Breast Cancer Cells Treated withα-Mangostin Extracted from Mangosteen Pericarp

(2012) Hitomi Kurose et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

In vivo toxicity and antitumor activity of mangosteen extract

(2012) Nuttavut Kosem et al.   Journal of Natural Medicines

Xanthones in Mangosteen Juice Are Absorbed and Partially Conjugated by Healthy Adults

(2012) Chureeporn Chitchumroonchokchai et al.   JOURNAL OF NUTRITION

Anti-tumorigenicity of dietary α-mangostin in an HT-29 colon cell xenograft model and the tissue distribution of xanthones and their phase II metabolites

(2012) Chureeporn Chitchumroonchokchai et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Effects of alpha-mangostin on the expression of anti-inflammatory genes in U937 cells

(2012) Szu-Hsiu Liu et al.   Chinese Medicine

α-Mangostin extracted from the pericarp of the mangosteen (Garcinia mangostanaLinn) reduces tumor growth and lymph node metastasis in an immunocompetent xenograft model of metastatic mammary cancer carrying a p53 mutation

(2011) Masa-Aki Shibata et al.   BMC Medicine

 -Mangostin, a xanthone from mangosteen fruit, promotes cell cycle arrest in prostate cancer and decreases xenograft tumor growth

(2011) J. J. Johnson et al.   CARCINOGENESIS

Nutritional Antioxidants and Adaptive Cell Responses: An Update

(2011) A. Speciale et al.   CURRENT MOLECULAR MEDICINE

Xanthones from Mangosteen Extracts as Natural Chemopreventive Agents: Potential Anticancer Drugs

(2011) T. Shan et al.   CURRENT MOLECULAR MEDICINE

Cytotoxic effect of xanthones from pericarp of the tropical fruit mangosteen (Garcinia mangostana Linn.) on human melanoma cells

(2011) Jing J. Wang et al.   FOOD AND CHEMICAL TOXICOLOGY

α- and γ-Mangostin inhibit the proliferation of colon cancer cells via β-catenin gene regulation in Wnt/cGMP signalling

(2011) Ji-Hye Yoo et al.   FOOD CHEMISTRY

α-Mangostin Induces Apoptosis in Human Chondrosarcoma Cells through Downregulation of ERK/JNK and Akt Signaling Pathway

(2011) Aungkana Krajarng et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

α-Mangostin, a Dietary Xanthone, Induces Autophagic Cell Death by Activating the AMP-Activated Protein Kinase Pathway in Glioblastoma Cells

(2011) A-Ching Chao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Pharmacokinetics of α-mangostin in rats after intravenous and oral application

(2011) Li Li et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Potential of Xanthones from Tropical Fruit Mangosteen as Anti-cancer Agents: Caspase-Dependent Apoptosis Induction In Vitro and in Mice

(2010) Ramida Watanapokasin et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Instability of, and generation of hydrogen peroxide by, phenolic compounds in cell culture media

(2010) Lee Hua Long et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

α-Mangostin Suppresses Phorbol 12-myristate 13-acetate-Induced MMP-2/MMP-9 Expressions via αvβ3 Integrin/FAK/ERK and NF-κB Signaling Pathway in Human Lung Adenocarcinoma A549 Cells

(2010) Yuan-Wei Shih et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Xanthones from Mangosteen Inhibit Inflammation in Human Macrophages and in Human Adipocytes Exposed to Macrophage-Conditioned Media

(2010) Akkarach Bumrungpert et al.   JOURNAL OF NUTRITION

Dietary isoflavones and vascular protection: Activation of cellular antioxidant defenses by SERMs or hormesis?

(2010) Richard C.M. Siow et al.   MOLECULAR ASPECTS OF MEDICINE

Apoptotic Effects of γ-Mangostin from the Fruit Hull of Garcinia mangostana on Human Malignant Glioma Cells

(2010) Hui-Fang Chang et al.   MOLECULES

Conjugated quercetin glucuronides as bioactive metabolites and precursors of aglyconein vivo

(2010) Junji Terao et al.   Food & Function

Inhibition of inflammatory mediators by polyphenolic plant extracts in human intestinal Caco-2 cells

(2009) Béatrice Romier-Crouzet et al.   FOOD AND CHEMICAL TOXICOLOGY

Bioavailability and Antioxidant Effects of a Xanthone-Rich Mangosteen (Garcinia mangostana) Product in Humans

(2009) Miwako Kondo et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

α-Mangostin Suppresses PC-3 Human Prostate Carcinoma Cell Metastasis by Inhibiting Matrix Metalloproteinase-2/9 and Urokinase-Plasminogen Expression through the JNK Signaling Pathway

(2009) Shun-Hsing Hung et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

α-Mangostin, A Novel Dietary Xanthone, Suppresses TPA-Mediated MMP-2 and MMP-9 Expressions through the ERK Signaling Pathway in MCF-7 Human Breast Adenocarcinoma Cells

(2009) Yuan-Bing Lee et al.   JOURNAL OF FOOD SCIENCE

Effect of a Mangosteen Dietary Supplement on Human Immune Function: A Randomized, Double-Blind, Placebo-Controlled Trial

(2009) Yu-Ping Tang et al.   JOURNAL OF MEDICINAL FOOD

Xanthones from Mangosteen Prevent Lipopolysaccharide-Mediated Inflammation and Insulin Resistance in Primary Cultures of Human Adipocytes

(2009) Akkarach Bumrungpert et al.   JOURNAL OF NUTRITION

Anti-inflammatory properties of a pomegranate extract and its metabolite urolithin-A in a colitis rat model and the effect of colon inflammation on phenolic metabolism☆

(2009) Mar Larrosa et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Bioaccessibility, biotransformation, and transport of α-mangostin from Garcinia mangostana (Mangosteen) using simulated digestion and Caco-2 human intestinal cells

(2009) Akkarach Bumrungpert et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Evaluation of Mangosteen juice blend on biomarkers of inflammation in obese subjects: a pilot, dose finding study

(2009) Jay K Udani et al.   Nutrition Journal

Garcinia mangostanaL.: a phytochemical and pharmacological review

(2009) Dmitriy Obolskiy et al.   PHYTOTHERAPY RESEARCH

Anti-oxidative and anti-inflammatory activities of some isolated constituents from the stem bark of Allanblackia monticola Staner L.C (Guttiferae)

(2009) E. L. Nguemfo et al.   INFLAMMOPHARMACOLOGY

Inhibitory effect of xanthones isolated from the pericarp of Garcinia mangostana L. on rat basophilic leukemia RBL-2H3 cell degranulation

(2008) Tomohiro Itoh et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Topical application of Garcinia mangostana L. pericarp gel as an adjunct to periodontal treatment

(2008) Supanee Rassameemasmaung et al.   COMPLEMENTARY THERAPIES IN MEDICINE

Medicinal properties of mangosteen (Garcinia mangostana)

(2008) José Pedraza-Chaverri et al.   FOOD AND CHEMICAL TOXICOLOGY

The wanderings of a free radical

(2008) Barry Halliwell   FREE RADICAL BIOLOGY AND MEDICINE

Effects of compounds from Garcinia mangostana on inflammatory mediators in RAW264.7 macrophage cells

(2008) Supinya Tewtrakul et al.   JOURNAL OF ETHNOPHARMACOLOGY

Structural Characterization, Biological Effects, and Synthetic Studies on Xanthones from Mangosteen (Garcinia mangostana), a Popular Botanical Dietary Supplement

(2008) Young-Won Chin et al.   MINI-REVIEWS IN ORGANIC CHEMISTRY

Anti-inflammatory activity of mangostins from Garcinia mangostana

(2007) Lih-Geeng Chen et al.   FOOD AND CHEMICAL TOXICOLOGY