The role of hypoxia-inducible factors in neovascular age-related macular degeneration: a gene therapy perspective

Luxturna: FDA documents reveal the value of a costly gene therapy

(2019) Jonathan J. Darrow   DRUG DISCOVERY TODAY

The urokinase-type plasminogen activator system as drug target in retinitis pigmentosa: New pre-clinical evidence in the rd10 mouse model

(2019) Maurizio Cammalleri et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Hif1a inactivation rescues photoreceptor degeneration induced by a chronic hypoxia-like stress

(2018) Maya Barben et al.   CELL DEATH AND DIFFERENTIATION

ANGIOPOIETIN-LIKE 4 CORRELATES WITH RESPONSE TO INTRAVITREAL RANIBIZUMAB INJECTIONS IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION

(2018) Jong Ho Kim et al.   RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES

Cell-specific gene therapy driven by an optimized hypoxia-regulated vector reduces choroidal neovascularization

(2018) Manas R. Biswal et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The Different Facades of Retinal and Choroidal Endothelial Cells in Response to Hypoxia

(2018) Effat Alizadeh et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

HIF signalling: The eyes have it

(2017) D.J. Peet et al.   EXPERIMENTAL CELL RESEARCH

Real-world visual acuity outcomes between ranibizumab and aflibercept in treatment of neovascular AMD in a large US data set

(2017) A Lotery et al.   EYE

Technique of retinal gene therapy: delivery of viral vector into the subretinal space

(2017) K Xue et al.   EYE

Hypoxia and inflammation in the release of VEGF and interleukins from human retinal pigment epithelial cells

(2017) Olli Arjamaa et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Lentiviral Vector Gene Transfer of Endostatin/Angiostatin for Macular Degeneration (GEM) Study

(2017) Peter A. Campochiaro et al.   HUMAN GENE THERAPY

Compliments of Factor H: What’s in it for AMD?

(2017) Mary J. Mattapallil et al.   IMMUNITY

Prevalence of Age-Related Macular Degeneration in Europe

(2017) Johanna M. Colijn et al.   OPHTHALMOLOGY

OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY REVEALS BLOOD FLOW IN CHOROIDAL NEOVASCULAR MEMBRANE IN REMISSION PHASE OF NEOVASCULAR AGE-RELATED MACULAR DEGENERATION

(2017) Yusuke Ichiyama et al.   RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES

Dysfunctional autophagy in RPE, a contributing factor in age-related macular degeneration

(2017) Nady Golestaneh et al.   Cell Death & Disease

Global causes of blindness and distance vision impairment 1990–2020: a systematic review and meta-analysis

(2017) Seth R Flaxman et al.   Lancet Global Health

HIF-1α induces VE-cadherin expression and modulates vasculogenic mimicry in esophageal carcinoma cells

(2017) Na-Na Tang et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Gene Transfer of Prolyl Hydroxylase Domain 2 Inhibits Hypoxia-inducible Angiogenesis in a Model of Choroidal Neovascularization

(2017) Anna Takei et al.   Scientific Reports

Drusen maculopathy: a risk factor for visual deterioration

(2016) Peep V. Algvere et al.   ACTA OPHTHALMOLOGICA

Differential hypoxic response of human choroidal and retinal endothelial cells proposes tissue heterogeneity of ocular angiogenesis

(2016) Parviz Mammadzada et al.   ACTA OPHTHALMOLOGICA

Hypoxia-inducible factor 3 biology: complexities and emerging themes

(2016) Cunming Duan   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Role of Autophagy in Hypoxia-Induced Angiogenesis of RF/6A Cells in vitro

(2016) Rong Li et al.   CURRENT EYE RESEARCH

Association between Vascular Endothelial Growth Factor Polymorphisms and Age-Related Macular Degeneration: An Updated Meta-Analysis

(2016) Martina Barchitta et al.   DISEASE MARKERS

Recombinant Haplotypes Narrow the ARMS2/HTRA1 Association Signal for Age-Related Macular Degeneration

(2016) Felix Grassmann et al.   GENETICS

Low-Dose Farnesyltransferase Inhibitor Suppresses HIF-1α and Snail Expression in Triple-Negative Breast Cancer MDA-MB-231 Cells In Vitro

(2016) Tomokazu Tanaka et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Impact of Heparan Sulfate Binding on Transduction of Retina by Recombinant Adeno-Associated Virus Vectors

(2016) Sanford L. Boye et al.   JOURNAL OF VIROLOGY

Generation and characterization of ABBV642, a dual variable domain immunoglobulin molecule (DVD-Ig) that potently neutralizes VEGF and PDGF-BB and is designed for the treatment of exudative age-related macular degeneration

(2016) Kun Ding et al.   mAbs

Mitochondria-Translocated PGK1 Functions as a Protein Kinase to Coordinate Glycolysis and the TCA Cycle in Tumorigenesis

(2016) Xinjian Li et al.   MOLECULAR CELL

Targeting VEGF in eye neovascularization: What's new?

(2016) Marialaura Amadio et al.   PHARMACOLOGICAL RESEARCH

Differentiating drusen: Drusen and drusen-like appearances associated with ageing, age-related macular degeneration, inherited eye disease and other pathological processes

(2016) Kamron N. Khan et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Recombinant Haplotypes Narrow the ARMS2/HTRA1 Association Signal for Age-Related Macular Degeneration

(2016) Felix Grassmann et al.   GENETICS

Phase 2a Randomized Clinical Trial: Safety and Post Hoc Analysis of Subretinal rAAV.sFLT-1 for Wet Age-related Macular Degeneration

(2016) Ian J. Constable et al.   EBioMedicine

Efficacy and Safety of rAAV2-ND4 Treatment for Leber’s Hereditary Optic Neuropathy

(2016) Xing Wan et al.   Scientific Reports

The HIF-1α/CXCR4 pathway supports hypoxia-induced metastasis of human osteosarcoma cells

(2015) Guofeng Guan et al.   CANCER LETTERS

Transcriptional regulation of the VEGF gene in dependence of individual genomic variations

(2015) Carmen S. Metzger et al.   CYTOKINE

Complement pathway biomarkers and age-related macular degeneration

(2015) M Gemenetzi et al.   EYE

Antiangiogenic Eye Gene Therapy

(2015) Thomas J. Corydon   HUMAN GENE THERAPY

Progress on hypoxia-inducible factor-3: Its structure, gene regulation and biological function (Review)

(2015) SHENG-LI YANG et al.   Molecular Medicine Reports

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

(2015) Lars G Fritsche et al.   NATURE GENETICS

M410, a combretastatin A4 analogue, disrupts microtubules and inhibits HIF-1α in human breast cancer cells

(2015) HANG YANG et al.   ONCOLOGY REPORTS

Growth of Geographic Atrophy in the Comparison of Age-related Macular Degeneration Treatments Trials

(2015) Juan E. Grunwald et al.   OPHTHALMOLOGY

Determination of N-retinylidene-N-retinylethanolamine (A2E) levels in central and peripheral areas of human retinal pigment epithelium

(2015) Leopold Adler et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Vascular-targeted photodynamic therapy in the treatment of neovascular age-related macular degeneration: Clinical perspectives

(2015) A. Kawczyk-Krupka et al.   Photodiagnosis and Photodynamic Therapy

Gene therapy: progress and predictions

(2015) Mary Collins et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Molecular pathogenesis of retinal and choroidal vascular diseases

(2015) Peter A. Campochiaro   PROGRESS IN RETINAL AND EYE RESEARCH

Intravitreal anti-VEGF injections for treating wet age-related macular degeneration: a systematic review and meta-analysis

(2015) Jing Yu et al.   Drug Design Development and Therapy

Modeling the interplay between the HIF-1 and p53 pathways in hypoxia

(2015) Chun-Hong Zhou et al.   Scientific Reports

Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD

(2014) Sayak K Mitter et al.   Autophagy

One year results of a phase 1 study of the safety and tolerability of combination therapy using sustained release intravitreal triamcinolone acetonide and ranibizumab for subfoveal neovascular AMD

(2014) Jennifer I Lim et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Neurons Limit Angiogenesis by Titrating VEGF in Retina

(2014) Keisuke Okabe et al.   CELL

αvβ3, αvβ5 and αvβ6 integrins in brain metastases of lung cancer

(2014) Anna Sophie Berghoff et al.   CLINICAL & EXPERIMENTAL METASTASIS

Comparative safety profiles of intravitreal bevacizumab, ranibizumab and pegaptanib: the analysis of the WHO database of adverse drug reactions

(2014) C. Biagi et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

The relationships between hypoxia-dependent markers: HIF-1alpha, EPO and EPOR in colorectal cancer

(2014) Marek Baltaziak et al.   FOLIA HISTOCHEMICA ET CYTOBIOLOGICA

Long-Term Episomal Transgene Expression from Mitotically Stable Integration-Deficient Lentiviral Vectors

(2014) Hanna Kymäläinen et al.   HUMAN GENE THERAPY

Rare and common variants in extracellular matrix gene Fibrillin 2 (FBN2) are associated with macular degeneration

(2014) Rinki Ratnapriya et al.   HUMAN MOLECULAR GENETICS

Hypoxia-mediated retinal neovascularization and vascular leakage in diabetic retina is suppressed by HIF-1α destabilization by SH-1242 and SH-1280, novel hsp90 inhibitors

(2014) Dong Hyun Jo et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

UPARANT: A Urokinase Receptor-Derived Peptide Inhibitor of VEGF-Driven Angiogenesis with Enhanced Stability and In Vitro and In Vivo Potency

(2014) M. V. Carriero et al.   MOLECULAR CANCER THERAPEUTICS

Hypoxia induces autophagy in human vascular endothelial cells in a hypoxia-inducible factor 1-dependent manner

(2014) JIANBO WU et al.   Molecular Medicine Reports

Elevated High-Density Lipoprotein Cholesterol and Age-Related Macular Degeneration: The Alienor Study

(2014) Audrey Cougnard-Grégoire et al.   PLoS One

The Histone Deacetylase Inhibitor, Vorinostat, Represses Hypoxia Inducible Factor 1 Alpha Expression through Translational Inhibition

(2014) Darren M. Hutt et al.   PLoS One

Vector platforms for gene therapy of inherited retinopathies

(2014) Ivana Trapani et al.   PROGRESS IN RETINAL AND EYE RESEARCH

INTRAVITREAL INJECTION TECHNIQUE AND MONITORING

(2014) Robert L. Avery et al.   RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES

Comparative study of photodynamic therapy monotherapy versus triplemanagement in age-related macular degeneration

(2014) Ahmet SELİM et al.   Turkish Journal Of Medical Sciences

Funduscopic results after 4-year follow-up treatment with ranibizumab for age-related macular degeneration in a region of Spain

(2014) Rosa M Coco et al.   BMC Ophthalmology

Expression and significance of MMP2 and HIF-1α in hepatocellular carcinoma

(2014) BIN WANG et al.   Oncology Letters

Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis

(2014) Wan Ling Wong et al.   Lancet Global Health

Response to Aflibercept in Patients With Persistent Exudation Despite Prior Treatment With Bevacizumab or Ranibizumab for Age-Related Macular Degeneration

(2014) James A. Eadie et al.   Ophthalmic Surgery Lasers & Imaging Retina

Hypoxic adaptation engages the CBP/CREST-induced coactivator complex of Creb-HIF-1α in transactivating murine neuroblastic glucose transporter

(2013) Shanthie Thamotharan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Honokiol inhibits pathological retinal neovascularization in oxygen-induced retinopathy mouse model

(2013) Divya Teja Vavilala et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A randomised controlled trial of ranibizumab with and without ketorolac eyedrops for exudative age-related macular degeneration

(2013) Andrea Russo et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Hypoxia-Inducible Factor-1 (HIF-1): A Potential Target for Intervention in Ocular Neovascular Diseases

(2013) Ramya Vadlapatla et al.   CURRENT DRUG TARGETS

Parainflammation associated with advanced glycation endproduct stimulation of RPE in vitro: Implications for age-related degenerative diseases of the eye

(2013) Tony Lin et al.   CYTOKINE

Gene therapy on demand: Site specific regulation of gene therapy

(2013) Agnieszka Jazwa et al.   GENE

Sustained delivery of a HIF-1 antagonist for ocular neovascularization

(2013) Takeshi Iwase et al.   JOURNAL OF CONTROLLED RELEASE

Ocular neovascularization

(2013) Peter A. Campochiaro   JOURNAL OF MOLECULAR MEDICINE-JMM

The Natural Inhibitor of DNA Topoisomerase I, Camptothecin, Modulates HIF-1  Activity by Changing miR Expression Patterns in Human Cancer Cells

(2013) D. Bertozzi et al.   MOLECULAR CANCER THERAPEUTICS

Complement factor H related proteins (CFHRs)

(2013) Christine Skerka et al.   MOLECULAR IMMUNOLOGY

A Comprehensive Review of Retinal Gene Therapy

(2013) Shannon E Boye et al.   MOLECULAR THERAPY

Complement Factor B Polymorphism and the Phenotype of Early Age-related Macular Degeneration

(2013) Irmela Mantel et al.   OPHTHALMIC GENETICS

Long-Term Effects of Vitamins C and E, β-Carotene, and Zinc on Age-related Macular Degeneration

(2013) Emily Y. Chew et al.   OPHTHALMOLOGY

Clinical Classification of Age-related Macular Degeneration

(2013) Frederick L. Ferris et al.   OPHTHALMOLOGY

OPTICAL COHERENCE TOMOGRAPHY–BASED CORRELATION BETWEEN CHOROIDAL THICKNESS AND DRUSEN LOAD IN DRY AGE-RELATED MACULAR DEGENERATION

(2013) Ashley Ko et al.   RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES

TREAT-AND-EXTEND BEVACIZUMAB FOR NEOVASCULAR AGE-RELATED MACULAR DEGENERATION

(2013) Ryan B. Rush et al.   RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES

In Vivo-Directed Evolution of a New Adeno-Associated Virus for Therapeutic Outer Retinal Gene Delivery from the Vitreous

(2013) D. Dalkara et al.   Science Translational Medicine

The HIF Signaling Pathway in Osteoblasts Directly Modulates Erythropoiesis through the Production of EPO

(2012) Erinn B. Rankin et al.   CELL

Small-molecule inhibitors of the HIF pathway and synthetic lethal interactions

(2012) Dylan T Jones et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Regulation of human monocarboxylate transporter 4 in skeletal muscle cells: The role of protein kinase C (PKC)

(2012) Katsuya Narumi et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Understanding age-related macular degeneration (AMD): Relationships between the photoreceptor/retinal pigment epithelium/Bruch’s membrane/choriocapillaris complex

(2012) Imran Bhutto et al.   MOLECULAR ASPECTS OF MEDICINE

Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation

(2012) S M Kumar et al.   ONCOGENE

The rs2071559 AAVEGFR-2Genotype Frequency Is Significantly Lower in Neovascular Age-Related Macular Degeneration Patients

(2012) Stefano Lazzeri et al.   TheScientificWorldJOURNAL

Reducing the Genetic Risk of Age-Related Macular Degeneration With Dietary Antioxidants, Zinc, and ω-3 Fatty Acids

(2011) Lintje Ho   ARCHIVES OF OPHTHALMOLOGY

Effect of hypoxia-inducible factor 1-alpha on hypoxia/reoxygenation-induced apoptosis in primary neonatal rat cardiomyocytes

(2011) Xiaoou Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1

(2011) Weibo Luo et al.   CELL

Mitoxantrone Inhibits HIF-1  Expression in a Topoisomerase II-Independent Pathway

(2011) Y.-M. Toh et al.   CLINICAL CANCER RESEARCH

Cancer Therapeutic Agents Targeting Hypoxia-Inducible Factor-1

(2011) R. Wang et al.   CURRENT MEDICINAL CHEMISTRY

Gene transfer for ocular neovascularization and macular edema

(2011) P A Campochiaro   GENE THERAPY

Surgical Approaches to Gene and Stem Cell Therapy for Retinal Disease

(2011) J. Timothy Stout et al.   HUMAN GENE THERAPY

Farnesyltransferase Inhibitor Manumycin Targets IL1β-Ras-HIF-1α Axis in Tumor Cells of Diverse Origin

(2011) Vivek Sharma et al.   INFLAMMATION

SOX9 Protein Induces a Chondrogenic Phenotype of Mesangial Cells and Contributes to Advanced Diabetic Nephropathy

(2011) Seiji Kishi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional regulation of HIF-1α under normoxia-is there more than post-translational regulation?

(2011) A. Kuschel et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Ranibizumab and Bevacizumab for Neovascular Age-Related Macular Degeneration

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

Cell culture model that mimics drusen formation and triggers complement activation associated with age-related macular degeneration

(2011) L. V. Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systemic and Ocular Safety of Intravitreal Anti-VEGF Therapies for Ocular Neovascular Disease

(2011) Michael Tolentino   SURVEY OF OPHTHALMOLOGY

Anti-VEGF Agents for Ocular Angiogenesis and Vascular Permeability

(2011) Kenichi Kimoto et al.   Journal of Ophthalmology

Basal laminar drusen and soft drusen have similar glycan composition

(2010) Yvonne B. D’souza et al.   CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE

Hypoxia-induced CCR7 expression via HIF-1α and HIF-2α correlates with migration and invasion in lung cancer cells

(2010) Yang Li et al.   CANCER BIOLOGY & THERAPY

Cancer Therapy By Targeting Hypoxia-Inducible Factor-1

(2010) Y. Li et al.   CURRENT CANCER DRUG TARGETS

Nutritional supplements for age-related macular degeneration

(2010) Nupura Krishnadev et al.   CURRENT OPINION IN OPHTHALMOLOGY

Digoxin inhibits retinal ischemia-induced HIF-1α expression and ocular neovascularization

(2010) Tsunehiko Yoshida et al.   FASEB JOURNAL

miR-20b modulates VEGF expression by targeting HIF-1α and STAT3 in MCF-7 breast cancer cells

(2010) Sandra Cascio et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A p38MAPK/HIF-1 Pathway Initiated by UVB Irradiation Is Required to Induce Noxa and Apoptosis of Human Keratinocytes

(2010) Kris Nys et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Quantitative Proteomics: Comparison of the Macular Bruch Membrane/Choroid Complex from Age-related Macular Degeneration and Normal Eyes

(2010) Xianglin Yuan et al.   MOLECULAR & CELLULAR PROTEOMICS

Inhibition of Choroidal Neovascularization in a Nonhuman Primate Model by Intravitreal Administration of an AAV2 Vector Expressing a Novel Anti-VEGF Molecule

(2010) Michael Lukason et al.   MOLECULAR THERAPY

Regulatory role of HIF-1α in the pathogenesis of age-related macular degeneration (AMD)

(2009) Olli Arjamaa et al.   AGEING RESEARCH REVIEWS

The humanurocortin 2gene is regulated by hypoxia: identification of a hypoxia-responsive element in the 3′-flanking region

(2009) Katrin Bühler et al.   BIOCHEMICAL JOURNAL

Synthesis and structural characterization of carboxyethylpyrrole-modified proteins: mediators of age-related macular degeneration

(2009) Liang Lu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Expression of hypoxia-inducible factor−1α and −2α in human choroidal neovascular membranes

(2009) Carl M. Sheridan et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Hypoxia-inducible factor-2 is a novel regulator of aberrant CXCL12 expression in multiple myeloma plasma cells

(2009) S. K. Martin et al.   HAEMATOLOGICA

Nanoparticle–integrin antagonist C16Y peptide treatment of choroidal neovascularization in rats

(2009) Hyuncheol Kim et al.   JOURNAL OF CONTROLLED RELEASE

Identification of small molecule compounds that inhibit the HIF-1 signaling pathway

(2009) Menghang Xia et al.   Molecular Cancer

Hypoxia-associated p38 mitogen-activated protein kinase-mediated androgen receptor activation and increased HIF-1α levels contribute to emergence of an aggressive phenotype in prostate cancer

(2009) L Khandrika et al.   ONCOGENE

Regulation of HIF-1α and VEGF by miR-20b Tunes Tumor Cells to Adapt to the Alteration of Oxygen Concentration

(2009) Zhang Lei et al.   PLoS One

The dynamic nature of Bruch's membrane

(2009) J.C. Booij et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Structural Basis for Binding of Hypoxia-Inducible Factor to the Oxygen-Sensing Prolyl Hydroxylases

(2009) Rasheduzzaman Chowdhury et al.   STRUCTURE

Neovascular age-related macular degeneration: too many theories, too little knowledge?

(2008) Anders Kvanta   ACTA OPHTHALMOLOGICA

Hypoxia-inducible factor (HIF)-1  directly enhances the transcriptional activity of stem cell factor (SCF) in response to hypoxia and epidermal growth factor (EGF)

(2008) Z.-B. Han et al.   CARCINOGENESIS

Biology of HIF-1α

(2008) A Weidemann et al.   CELL DEATH AND DIFFERENTIATION

Anti-VEGF therapy: comparison of current and future agents

(2008) D J Pieramici et al.   EYE

The angiopoietin-2 gene of endothelial cells is up-regulated in hypoxia by a HIF binding site located in its first intron and by the central factors GATA-2 and Ets-1

(2008) Marie-Pierre Simon et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Retinal Pigment Epithelium Lipofuscin Proteomics

(2008) Kwok-Peng Ng et al.   MOLECULAR & CELLULAR PROTEOMICS

Direct regulation of TWIST by HIF-1α promotes metastasis

(2008) Muh-Hwa Yang et al.   NATURE CELL BIOLOGY

Nuclear translocation of hypoxia-inducible factors (HIFs): Involvement of the classical importin α/β pathway

(2007) Reinhard Depping et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Hypoxia regulation of facilitated glucose transporter-1 and glucose transporter-3 in mouse chondrocytes mediated by HIF-1α

(2007) Bu-Fang Ren et al.   JOINT BONE SPINE