Cell-specific gene therapy driven by an optimized hypoxia-regulated vector reduces choroidal neovascularization

Lentiviral Vector Gene Transfer of Endostatin/Angiostatin for Macular Degeneration (GEM) Study

(2017) Peter A. Campochiaro et al.   HUMAN GENE THERAPY

Molecular mechanisms of subretinal fibrosis in age-related macular degeneration

(2016) Keijiro Ishikawa et al.   EXPERIMENTAL EYE RESEARCH

Current advances in the treatment of neovascular age-related macular degeneration

(2016) Victor M. Villegas et al.   Expert Opinion on Drug Delivery

Anti–Vascular Endothelial Growth Factor Agents in the Treatment of Retinal Disease

(2016) Peter A. Campochiaro et al.   OPHTHALMOLOGY

Evaluating the Validity of the Age-Related Eye Disease Study Grading Scale for Age-Related Macular Degeneration

(2016) Susan Vitale et al.   JAMA Ophthalmology

Retinal gene delivery by adeno-associated virus (AAV) vectors: Strategies and applications

(2015) Christian Schön et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Systemic treatment with a 5HT1a agonist induces anti-oxidant protection and preserves the retina from mitochondrial oxidative stress

(2015) Manas R. Biswal et al.   EXPERIMENTAL EYE RESEARCH

A Simple Optical Coherence Tomography Quantification Method for Choroidal Neovascularization

(2015) Rania S. Sulaiman et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

Multigenic lentiviral vectors for combined and tissue-specific expression of miRNA- and protein-based antiangiogenic factors

(2015) Anne Louise Askou et al.   Molecular Therapy-Methods & Clinical Development

A Hypoxia-Responsive Glial Cell-Specific Gene Therapy Vector for Targeting Retinal Neovascularization

(2014) M. R. Biswal et al.   INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Spectral-Domain Optical Coherence Tomography of the Rodent Eye: Highlighting Layers of the Outer Retina Using Signal Averaging and Comparison with Histology

(2014) Adeline Berger et al.   PLoS One

Oxygen Sensing, Hypoxia-Inducible Factors, and Disease Pathophysiology

(2013) Gregg L. Semenza   Annual Review of Pathology-Mechanisms of Disease

Sustained delivery of a HIF-1 antagonist for ocular neovascularization

(2013) Takeshi Iwase et al.   JOURNAL OF CONTROLLED RELEASE

Ocular neovascularization

(2013) Peter A. Campochiaro   JOURNAL OF MOLECULAR MEDICINE-JMM

Laser-induced choroidal neovascularization model to study age-related macular degeneration in mice

(2013) Vincent Lambert et al.   Nature Protocols

Risks of Adverse Events With Therapies for Age-Related Macular Degeneration: A Response

(2012) Toni Williams   ARCHIVES OF OPHTHALMOLOGY

Evaluation of the siRNA PF-04523655 versus Ranibizumab for the Treatment of Neovascular Age-related Macular Degeneration (MONET Study)

(2012) Quan Dong Nguyen et al.   OPHTHALMOLOGY

Myositis Ossificans

(2011) Deborah A. Martin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Self-complementary AAV5 vector facilitates quicker transgene expression in photoreceptor and retinal pigment epithelial cells of normal mouse

(2010) Fansheng Kong et al.   EXPERIMENTAL EYE RESEARCH

Inhibitory efficacy of hypoxia-inducible factor 1α short hairpin RNA plasmid DNA-loaded poly (D, L-lactide-co-glycolide) nanoparticles on choroidal neovascularization in a laser-induced rat model

(2009) C Zhang et al.   GENE THERAPY

Expression of hypoxia-inducible factor−1α and −2α in human choroidal neovascular membranes

(2009) Carl M. Sheridan et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Equine Infectious Anemia Viral Vector-Mediated Codelivery of Endostatin and Angiostatin Driven by Retinal Pigmented Epithelium-Specific VMD2 Promoter Inhibits Choroidal Neovascularization

(2009) Shu Kachi et al.   HUMAN GENE THERAPY

Lentiviral-mediated Overexpression of Bcl-xL Protects Primary Endothelial Cells From Ischemia/Reperfusion Injury–induced Apoptosis

(2009) Jing Zhao et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

An essential role for RPE-derived soluble VEGF in the maintenance of the choriocapillaris

(2009) M. Saint-Geniez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endogenous VEGF Is Required for Visual Function: Evidence for a Survival Role on Müller Cells and Photoreceptors

(2008) Magali Saint-Geniez et al.   PLoS One