Efficacy and Safety of rAAV2-ND4 Treatment for Leber’s Hereditary Optic Neuropathy
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Title
Efficacy and Safety of rAAV2-ND4 Treatment for Leber’s Hereditary Optic Neuropathy
Authors
Keywords
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Journal
Scientific Reports
Volume 6, Issue 1, Pages -
Publisher
Springer Nature
Online
2016-02-19
DOI
10.1038/srep21587
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Note: Only part of the references are listed.- LHON Gene Therapy Vector Prevents Visual Loss and Optic Neuropathy Induced by G11778A Mutant Mitochondrial DNA: Biodistribution and Toxicology Profile
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- Safety and Effects of the Vector for the Leber Hereditary Optic Neuropathy Gene Therapy Clinical Trial
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- Leber's hereditary optic neuropathy masquerading as optic neuritis with spontaneous visual recovery
- (2013) Tsui-Kang Hsu et al. Clinical and Experimental Optometry
- Effect of EPI-743 on the Clinical Course of the Mitochondrial Disease Leber Hereditary Optic Neuropathy
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- Adeno-associated virus-mediated gene delivery of the human ND4 complex I subunit in rabbit eyes
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- Applications of the method of high resolution melting analysis for diagnosis of Leber's disease and the three primary mutation spectrum of LHON in the Han Chinese population
- (2012) Guanglin Cui et al. GENE
- Effects of Idebenone on Color Vision in Patients With Leber Hereditary Optic Neuropathy
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- Treatment of Leber hereditary optic neuropathy
- (2011) N. J. Newman BRAIN
- Idebenone Treatment In Leber's Hereditary Optic Neuropathy
- (2011) V. Carelli et al. BRAIN
- A randomized placebo-controlled trial of idebenone in Leber’s hereditary optic neuropathy
- (2011) Thomas Klopstock et al. BRAIN
- Oestrogens ameliorate mitochondrial dysfunction in Leber’s hereditary optic neuropathy
- (2010) Carla Giordano et al. BRAIN
- Adeno-associated Virus Vectors Serotype 2 Induce Prolonged Proliferation of Capsid-Specific CD8+ T Cells in Mice
- (2010) Hua Li et al. MOLECULAR THERAPY
- Mitochondrial optic neuropathies – Disease mechanisms and therapeutic strategies
- (2010) Patrick Yu-Wai-Man et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Optimized Allotopic Expression of the Human Mitochondrial ND4 Prevents Blindness in a Rat Model of Mitochondrial Dysfunction
- (2008) Sami Ellouze et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis
- (2008) Albert M. Maguire et al. NEW ENGLAND JOURNAL OF MEDICINE
- Effect of Gene Therapy on Visual Function in Leber's Congenital Amaurosis
- (2008) James W.B. Bainbridge et al. NEW ENGLAND JOURNAL OF MEDICINE
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