Farnesyltransferase Inhibitor Manumycin Targets IL1β-Ras-HIF-1α Axis in Tumor Cells of Diverse Origin

Inter-connection between mitochondria and HIFs

(2010) Kathryn V. Tormos et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

At the crossroads of cancer and inflammation: Ras rewires an HIF-driven IL-1 autocrine loop

(2010) Stefan Kaluz et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Ras regulates interleukin-1β-induced HIF-1α transcriptional activity in glioblastoma

(2010) Vivek Sharma et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Manumycin inhibits STAT3, telomerase activity, and growth of glioma cells by elevating intracellular reactive oxygen species generation

(2009) Deobrat Dixit et al.   FREE RADICAL BIOLOGY AND MEDICINE

Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

(2009) G L Semenza   ONCOGENE

The role of hypoxia-inducible factors in tumorigenesis

(2008) E B Rankin et al.   CELL DEATH AND DIFFERENTIATION