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Title
Behind the Wheel of Epithelial Plasticity in KRAS-Driven Cancers
Authors
Keywords
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Journal
Frontiers in Oncology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-10-11
DOI
10.3389/fonc.2019.01049
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Note: Only part of the references are listed.- Progress in targeting RAS with small molecule drugs
- (2019) Frank McCormick BIOCHEMICAL JOURNAL
- MEK1/2 inhibitor withdrawal reverses acquired resistance driven by BRAFV600E amplification whereas KRASG13D amplification promotes EMT-chemoresistance
- (2019) Matthew J. Sale et al. Nature Communications
- Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies
- (2019) Meng Yuan et al. Cell Host & Microbe
- Proteogenomic Network Analysis of Context-Specific KRAS Signaling in Mouse-to-Human Cross-Species Translation
- (2019) Douglas K. Brubaker et al. Cell Systems
- The plasticity of pancreatic cancer metabolism in tumor progression and therapeutic resistance
- (2018) Douglas E. Biancur et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- The Warburg effect in human pancreatic cancer cells triggers cachexia in athymic mice carrying the cancer cells
- (2018) Feng Wang et al. BMC CANCER
- Activation of the Receptor Tyrosine Kinase AXL Regulates the Immune Microenvironment in Glioblastoma
- (2018) Hirokazu Sadahiro et al. CANCER RESEARCH
- Kras and Tp53 mutations cause cholangiocyte- and hepatocyte-derived cholangiocarcinoma
- (2018) Margaret A Hill et al. CANCER RESEARCH
- SnapShot: CGAS-STING Signaling
- (2018) Lorenzo Galluzzi et al. CELL
- EMT Subtype Influences Epithelial Plasticity and Mode of Cell Migration
- (2018) Nicole M. Aiello et al. DEVELOPMENTAL CELL
- TP-0903 inhibits neuroblastoma cell growth and enhances the sensitivity to conventional chemotherapy
- (2018) Sanja Aveic et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Loss of Pten and Activation of Kras Synergistically Induce Formation of Intraductal Papillary Mucinous Neoplasia From Pancreatic Ductal Cells in Mice
- (2018) Janel L. Kopp et al. GASTROENTEROLOGY
- Novel K-Ras G12C Switch-II Covalent Binders Destabilize Ras and Accelerate Nucleotide Exchange
- (2018) Chimno I. Nnadi et al. Journal of Chemical Information and Modeling
- Chromosomal instability drives metastasis through a cytosolic DNA response
- (2018) Samuel F. Bakhoum et al. NATURE
- Tumor innate immunity primed by specific interferon-stimulated endogenous retroviruses
- (2018) Israel Cañadas et al. NATURE MEDICINE
- Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells
- (2018) Akiko Takahashi et al. Nature Communications
- Differential Effector Engagement by Oncogenic KRAS
- (2018) Tina L. Yuan et al. Cell Reports
- Mechanistic regulation of epithelial-to-mesenchymal transition through RAS signaling pathway and therapeutic implications in human cancer
- (2018) Kiran Tripathi et al. Journal of Cell Communication and Signaling
- The Multifaceted Role of Chromosomal Instability in Cancer and Its Microenvironment
- (2018) Samuel F. Bakhoum et al. CELL
- Dual reporter genetic mouse models of pancreatic cancer identify an epithelial‐to‐mesenchymal transition‐independent metastasis program
- (2018) Yang Chen et al. EMBO Molecular Medicine
- Does Axl have potential as a therapeutic target in pancreatic cancer?
- (2018) Wenting Du et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- O-GlcNAcylation is required for mutant KRAS-induced lung tumorigenesis
- (2018) Kekoa Taparra et al. JOURNAL OF CLINICAL INVESTIGATION
- Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes
- (2018) Sebastian Mueller et al. NATURE
- Chronic lymphocytic leukemia cells from ibrutinib treated patients are sensitive to Axl receptor tyrosine kinase inhibitor therapy
- (2018) Sutapa Sinha et al. Oncotarget
- Metabolic Dependencies in Pancreatic Cancer
- (2018) Ali Vaziri-Gohar et al. Frontiers in Oncology
- Epithelial, mesenchymal and hybrid epithelial/mesenchymal phenotypes and their clinical relevance in cancer metastasis
- (2017) Minal Garg EXPERT REVIEWS IN MOLECULAR MEDICINE
- Inhibition of the Receptor Tyrosine Kinase AXL Restores Paclitaxel Chemosensitivity in Uterine Serous Cancer
- (2017) Marguerite L. Palisoul et al. MOLECULAR CANCER THERAPEUTICS
- EMT and MET: necessary or permissive for metastasis?
- (2017) Mohit Kumar Jolly et al. Molecular Oncology
- The EMT spectrum and therapeutic opportunities
- (2017) Dominic C. Voon et al. Molecular Oncology
- New insights into the role of EMT in tumor immune escape
- (2017) Stéphane Terry et al. Molecular Oncology
- Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer
- (2017) Giannicola Genovese et al. NATURE
- Cytoplasmic chromatin triggers inflammation in senescence and cancer
- (2017) Zhixun Dou et al. NATURE
- Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence
- (2017) Selene Glück et al. NATURE CELL BIOLOGY
- The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer
- (2017) Angela M. Krebs et al. NATURE CELL BIOLOGY
- Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer
- (2017) Alvin P Makohon-Moore et al. NATURE GENETICS
- Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy
- (2017) Teresa Davoli et al. SCIENCE
- Cells of origin of pancreatic neoplasms
- (2017) Junpei Yamaguchi et al. SURGERY TODAY
- Targeting AXL overcomes resistance to docetaxel therapy in advanced prostate cancer
- (2017) Jian-Zhong Lin et al. Oncotarget
- KRAS: The Critical Driver and Therapeutic Target for Pancreatic Cancer
- (2017) Andrew M. Waters et al. Cold Spring Harbor Perspectives in Medicine
- Epithelial-Mesenchymal Transition in Pancreatic Cancer: A Review
- (2017) Shuai Wang et al. Biomed Research International
- Assessment of TANK-binding kinase 1 as a therapeutic target in cancer
- (2017) Victoria H. Cruz et al. Journal of Cell Communication and Signaling
- EMT and Treatment Resistance in Pancreatic Cancer
- (2017) Nicola Gaianigo et al. Cancers
- 3D collagen fibrillar microstructure guides pancreatic cancer cell phenotype and serves as a critical design parameter for phenotypic models of EMT
- (2017) T. J. Puls et al. PLoS One
- In Vivo Visualization and Characterization of Epithelial–Mesenchymal Transition in Breast Tumors
- (2016) Zhen Zhao et al. CANCER RESEARCH
- EMT: 2016
- (2016) M. Angela Nieto et al. CELL
- Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma
- (2016) Willy Hugo et al. CELL
- Axl Blockade by BGB324 Inhibits BCR-ABL Tyrosine Kinase Inhibitor–Sensitive and -Resistant Chronic Myeloid Leukemia
- (2016) Isabel Ben-Batalla et al. CLINICAL CANCER RESEARCH
- ZEB1 drives epithelial-to-mesenchymal transition in lung cancer
- (2016) Jill E. Larsen et al. JOURNAL OF CLINICAL INVESTIGATION
- Tumor metabolism, cancer cell transporters, and microenvironmental resistance
- (2016) Khalid O. Alfarouk JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns
- (2016) Faiyaz Notta et al. NATURE
- Genomic analyses identify molecular subtypes of pancreatic cancer
- (2016) Peter Bailey et al. NATURE
- Allele-specific inhibitors inactivate mutant KRAS G12C by a trapping mechanism
- (2016) P. Lito et al. SCIENCE
- The GAS6-AXL signaling network is a mesenchymal (Mes) molecular subtype-specific therapeutic target for ovarian cancer
- (2016) J. Antony et al. Science Signaling
- Bmi1 combines with oncogenic KRAS to induce malignant transformation of human pancreatic duct cells in vitro
- (2016) Shao-jie Chen et al. TUMOR BIOLOGY
- Selective Inhibition of Oncogenic KRAS Output with Small Molecules Targeting the Inactive State
- (2016) M. P. Patricelli et al. Cancer Discovery
- The GAS6-AXL signaling network is a mesenchymal (Mes) molecular subtype-specific therapeutic target for ovarian cancer
- (2016) J. Antony et al. Science Signaling
- Tumor Budding: The Name is EMT. Partial EMT.
- (2016) Alexandru Grigore et al. Journal of Clinical Medicine
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- (2016) Tsuneo Ikenoue et al. Scientific Reports
- Immunological Effects of Conventional Chemotherapy and Targeted Anticancer Agents
- (2015) Lorenzo Galluzzi et al. CANCER CELL
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- (2015) Amanda Kirane et al. CANCER RESEARCH
- AXL Is a Logical Molecular Target in Head and Neck Squamous Cell Carcinoma
- (2015) T. M. Brand et al. CLINICAL CANCER RESEARCH
- Targeting RAS Membrane Association: Back to the Future for Anti-RAS Drug Discovery?
- (2015) A. D. Cox et al. CLINICAL CANCER RESEARCH
- A little sugar goes a long way: The cell biology of O-GlcNAc
- (2015) Michelle R. Bond et al. JOURNAL OF CELL BIOLOGY
- AXL Inhibitors in Cancer: A Medicinal Chemistry Perspective
- (2015) Samuel H. Myers et al. JOURNAL OF MEDICINAL CHEMISTRY
- Differential Reprogramming of Isogenic Colorectal Cancer Cells by Distinct Activating KRAS Mutations
- (2015) Dean E. Hammond et al. JOURNAL OF PROTEOME RESEARCH
- Receptor tyrosine kinase Axl is required for resistance of leukemic cells to FLT3-targeted therapy in acute myeloid leukemia
- (2015) I-K Park et al. LEUKEMIA
- Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
- (2015) Xiaofeng Zheng et al. NATURE
- Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance
- (2015) Kari R. Fischer et al. NATURE
- Distinct EMT programs control normal mammary stem cells and tumour-initiating cells
- (2015) Xin Ye et al. NATURE
- Whole genomes redefine the mutational landscape of pancreatic cancer
- (2015) Nicola Waddell et al. NATURE
- STAT3 integrates cooperative Ras and TGF-β signals that induce Snail expression
- (2015) M Saitoh et al. ONCOGENE
- Epithelial–Mesenchymal Plasticity: A Central Regulator of Cancer Progression
- (2015) Xin Ye et al. TRENDS IN CELL BIOLOGY
- Hyperoside induces apoptosis and inhibits growth in pancreatic cancer via Bcl-2 family and NF-κB signaling pathway both in vitro and in vivo
- (2015) Yilong Li et al. TUMOR BIOLOGY
- Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets
- (2015) Agnieszka K. Witkiewicz et al. Nature Communications
- A new role for the PI3K/Akt signaling pathway in the epithelial-mesenchymal transition
- (2015) Wenting Xu et al. Cell Adhesion & Migration
- Small molecule inhibition of Axl receptor tyrosine kinase potently suppresses multiple malignant properties of glioma cells
- (2015) Mikaella Vouri et al. Oncotarget
- Dynamics of Tumor Heterogeneity Derived from Clonal Karyotypic Evolution
- (2015) Ashley M. Laughney et al. Cell Reports
- Mesenchymal Cancer Cell-Stroma Crosstalk Promotes Niche Activation, Epithelial Reversion, and Metastatic Colonization
- (2015) Yaiza del Pozo Martin et al. Cell Reports
- AUY922 Effectively Overcomes MET- and AXL-Mediated Resistance to EGFR-TKI in Lung Cancer Cells
- (2015) Yun Jung Choi et al. PLoS One
- Hypoxia-Inducible Factor-1 Promotes Pancreatic Ductal Adenocarcinoma Invasion and Metastasis by Activating Transcription of the Actin-Bundling Protein Fascin
- (2014) X. Zhao et al. CANCER RESEARCH
- Transient SNAIL1 Expression Is Necessary for Metastatic Competence in Breast Cancer
- (2014) H. D. Tran et al. CANCER RESEARCH
- KRAS and YAP1 Converge to Regulate EMT and Tumor Survival
- (2014) Diane D. Shao et al. CELL
- Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression
- (2014) G Denecker et al. CELL DEATH AND DIFFERENTIATION
- Epigenetic Regulation of EMT: The Snail Story
- (2014) Yiwei Lin et al. CURRENT PHARMACEUTICAL DESIGN
- ZEB1 sensitizes lung adenocarcinoma to metastasis suppression by PI3K antagonism
- (2014) Yanan Yang et al. JOURNAL OF CLINICAL INVESTIGATION
- Cytosolic-DNA-Mediated, STING-Dependent Proinflammatory Gene Induction Necessitates Canonical NF- B Activation through TBK1
- (2014) T. Abe et al. JOURNAL OF VIROLOGY
- Targeting TBK1 Inhibits Migration and Resistance to MEK Inhibitors in Mutant NRAS Melanoma
- (2014) Ha Linh Vu et al. MOLECULAR CANCER RESEARCH
- Drugging the undruggable RAS: Mission Possible?
- (2014) Adrienne D. Cox et al. NATURE REVIEWS DRUG DISCOVERY
- Molecular mechanisms of epithelial–mesenchymal transition
- (2014) Samy Lamouille et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Effects of the HIF-1α and NF-κB loop on epithelial-mesenchymal transition and chemoresistance induced by hypoxia in pancreatic cancer cells
- (2014) ZHUO-XIN CHENG et al. ONCOLOGY REPORTS
- Transcription Regulation of E-Cadherin by Zinc Finger E-Box Binding Homeobox Proteins in Solid Tumors
- (2014) Thian-Sze Wong et al. Biomed Research International
- Therapeutic Targeting of Oncogenic K-Ras by a Covalent Catalytic Site Inhibitor
- (2013) Sang Min Lim et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Resveratrol decreases breast cancer cell viability and glucose metabolism by inhibiting 6-phosphofructo-1-kinase
- (2013) Lilian S. Gomez et al. BIOCHIMIE
- Aneuploidy and chromosomal instability: a vicious cycle driving cellular evolution and cancer genome chaos
- (2013) Tamara A. Potapova et al. CANCER AND METASTASIS REVIEWS
- A Switch in the Expression of Embryonic EMT-Inducers Drives the Development of Malignant Melanoma
- (2013) Julie Caramel et al. CANCER CELL
- Sox4 Is a Master Regulator of Epithelial-Mesenchymal Transition by Controlling Ezh2 Expression and Epigenetic Reprogramming
- (2013) Neha Tiwari et al. CANCER CELL
- Loss of TBK1 Induces Epithelial-Mesenchymal Transition in the Breast Cancer Cells by ER Downregulation
- (2013) K.-M. Yang et al. CANCER RESEARCH
- Cell Lineage Tracing Reveals a Biliary Origin of Intrahepatic Cholangiocarcinoma
- (2013) R. V. Guest et al. CANCER RESEARCH
- Collagen Signaling Enhances Tumor Progression after Anti-VEGF Therapy in a Murine Model of Pancreatic Ductal Adenocarcinoma
- (2013) K. Y. Aguilera et al. CANCER RESEARCH
- Gas6/Axl pathway promotes tumor invasion through the transcriptional activation of Slug in hepatocellular carcinoma
- (2013) Hsin-Jung Lee et al. CARCINOGENESIS
- Poised Chromatin at the ZEB1 Promoter Enables Breast Cancer Cell Plasticity and Enhances Tumorigenicity
- (2013) Christine L. Chaffer et al. CELL
- Hypoxia-Induced Snail Expression Through Transcriptional Regulation by HIF-1α in Pancreatic Cancer Cells
- (2013) Guang-hui Zhu et al. DIGESTIVE DISEASES AND SCIENCES
- The complexity of NF-κB signaling in inflammation and cancer
- (2013) Bastian Hoesel et al. Molecular Cancer
- Snail Cooperates with KrasG12D to Promote Pancreatic Fibrosis
- (2013) M. A. Shields et al. MOLECULAR CANCER RESEARCH
- K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions
- (2013) Jonathan M. Ostrem et al. NATURE
- The epigenetics of epithelial-mesenchymal plasticity in cancer
- (2013) Wai Leong Tam et al. NATURE MEDICINE
- AXL induces epithelial-to-mesenchymal transition and regulates the function of breast cancer stem cells
- (2013) M K Asiedu et al. ONCOGENE
- Preclinical validation of AXL receptor as a target for antibody-based pancreatic cancer immunotherapy
- (2013) W Leconet et al. ONCOGENE
- Epithelial-mesenchymal transition - activating transcription factors - multifunctional regulators in cancer
- (2013) Minal Garg World Journal of Stem Cells
- Identification of Sox9-Dependent Acinar-to-Ductal Reprogramming as the Principal Mechanism for Initiation of Pancreatic Ductal Adenocarcinoma
- (2012) Janel L. Kopp et al. CANCER CELL
- Metastatic Colonization Requires the Repression of the Epithelial-Mesenchymal Transition Inducer Prrx1
- (2012) Oscar H. Ocaña et al. CANCER CELL
- A Comprehensive Survey of Ras Mutations in Cancer
- (2012) I. A. Prior et al. CANCER RESEARCH
- Zinc finger E-box binding homeobox 1 promotes invasion and bone metastasis of small cell lung cancerin vitroandin vivo
- (2012) Yi Liu et al. CANCER SCIENCE
- EMT and Dissemination Precede Pancreatic Tumor Formation
- (2012) Andrew D. Rhim et al. CELL
- MiR-34 and SNAIL: Another double-negative feedback loop controlling cellular plasticity/EMT governed by p53
- (2012) Thomas Brabletz CELL CYCLE
- Epithelial-to-mesenchymal transition (EMT) confers primary resistance to trastuzumab (Herceptin)
- (2012) Cristina Oliveras-Ferraros et al. CELL CYCLE
- An Epithelial-Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance
- (2012) L. A. Byers et al. CLINICAL CANCER RESEARCH
- ZEB/miR-200 feedback loop: At the crossroads of signal transduction in cancer
- (2012) Louise Hill et al. INTERNATIONAL JOURNAL OF CANCER
- Cholangiocarcinomas can originate from hepatocytes in mice
- (2012) Biao Fan et al. JOURNAL OF CLINICAL INVESTIGATION
- ZEB1 drives prometastatic actin cytoskeletal remodeling by downregulating miR-34a expression
- (2012) Young-Ho Ahn et al. JOURNAL OF CLINICAL INVESTIGATION
- Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes
- (2012) Sayaka Sekiya et al. JOURNAL OF CLINICAL INVESTIGATION
- Effect of KRAS Oncogene Substitutions on Protein Behavior: Implications for Signaling and Clinical Outcome
- (2012) Nathan T. Ihle et al. JNCI-Journal of the National Cancer Institute
- Hsp90 stress potentiates rapid cellular adaptation through induction of aneuploidy
- (2012) Guangbo Chen et al. NATURE
- Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
- (2012) Andrew V. Biankin et al. NATURE
- Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer
- (2012) Zhenfeng Zhang et al. NATURE GENETICS
- linking metabolism to epigenetics through O-GlcNAcylation
- (2012) John A. Hanover et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Phosphofructokinase 1 Glycosylation Regulates Cell Growth and Metabolism
- (2012) W. Yi et al. SCIENCE
- The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.
- (2012) Ethan Cerami et al. Cancer Discovery
- Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells
- (2011) Piyush B. Gupta et al. CELL
- Pancreatic ductal cells in development, regeneration, and neoplasia
- (2011) Maximilian Reichert et al. JOURNAL OF CLINICAL INVESTIGATION
- TBK1 Directly Engages Akt/PKB Survival Signaling to Support Oncogenic Transformation
- (2011) Yi-Hung Ou et al. MOLECULAR CELL
- Interactions between cancer stem cells and their niche govern metastatic colonization
- (2011) Ilaria Malanchi et al. NATURE
- Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy
- (2011) Eric A Collisson et al. NATURE MEDICINE
- Nuclear Factor-κB–Dependent Epithelial to Mesenchymal Transition Induced by HIF-1α Activation in Pancreatic Cancer Cells under Hypoxic Conditions
- (2011) Zhuo-Xin Cheng et al. PLoS One
- Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state
- (2011) C. L. Chaffer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth
- (2011) P. Wild et al. SCIENCE
- Genotypic and Histological Evolution of Lung Cancers Acquiring Resistance to EGFR Inhibitors
- (2011) L. V. Sequist et al. Science Translational Medicine
- Overexpression of receptor tyrosine kinase Axl promotes tumor cell invasion and survival in pancreatic ductal adenocarcinoma
- (2010) Xianzhou Song et al. CANCER
- The Axl receptor tyrosine kinase confers an adverse prognostic influence in pancreatic cancer and represents a new therapeutic target
- (2010) Jan-Bart M. Koorstra et al. CANCER BIOLOGY & THERAPY
- Knockdown of ZEB1, a master epithelial-to-mesenchymal transition (EMT) gene, suppresses anchorage-independent cell growth of lung cancer cells
- (2010) Yoshihiro Takeyama et al. CANCER LETTERS
- R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer
- (2010) S. J. Holland et al. CANCER RESEARCH
- The ZEB/miR-200 feedback loop—a motor of cellular plasticity in development and cancer?
- (2010) Simone Brabletz et al. EMBO REPORTS
- Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast
- (2010) Norman Pavelka et al. NATURE
- The patterns and dynamics of genomic instability in metastatic pancreatic cancer
- (2010) Peter J. Campbell et al. NATURE
- Pancreatic cancer: understanding and overcoming chemoresistance
- (2010) Zhiwei Wang et al. Nature Reviews Gastroenterology & Hepatology
- EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer
- (2010) A Singh et al. ONCOGENE
- Cancer Metastasis Is Accelerated through Immunosuppression during Snail-Induced EMT of Cancer Cells
- (2009) Chie Kudo-Saito et al. CANCER CELL
- A Gene Expression Signature Associated with “K-Ras Addiction” Reveals Regulators of EMT and Tumor Cell Survival
- (2009) Anurag Singh et al. CANCER CELL
- Epithelial to Mesenchymal Transition Contributes to Drug Resistance in Pancreatic Cancer
- (2009) T. Arumugam et al. CANCER RESEARCH
- Epithelial-Mesenchymal Transitions in Development and Disease
- (2009) Jean Paul Thiery et al. CELL
- Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression
- (2009) D. L. Gibbons et al. GENES & DEVELOPMENT
- Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
- (2009) David A. Barbie et al. NATURE
- Localized and reversible TGFβ signalling switches breast cancer cells from cohesive to single cell motility
- (2009) Silvia Giampieri et al. NATURE CELL BIOLOGY
- A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer
- (2009) Pierre Farmer et al. NATURE MEDICINE
- Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features
- (2009) C. J. Creighton et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival
- (2009) C. Gjerdrum et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
- (2008) Ulrike Burk et al. EMBO REPORTS
- In brain, Axl recruits Grb2 and the p85 regulatory subunit of PI3 kinase; in vitro mutagenesis defines the requisite binding sites for downstream Akt activation
- (2008) Jason G. Weinger et al. JOURNAL OF NEUROCHEMISTRY
- Ras oncogenes: split personalities
- (2008) Antoine E. Karnoub et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Epithelial-Mesenchymal Transition Markers in Pancreatic Ductal Adenocarcinoma
- (2008) Justin M.M. Cates et al. PANCREAS
- Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia
- (2008) J.-P. De La O et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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