ZEB1 drives prometastatic actin cytoskeletal remodeling by downregulating miR-34a expression

miR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions

(2012) Helge Siemens et al.   CELL CYCLE

p63-microRNA feedback in keratinocyte senescence

(2012) P. Rivetti di Val Cervo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ZEB proteins link cell motility with cell cycle control and cell survival in cancer

(2011) Gareth Browne et al.   CELL CYCLE

The diverse roles of Rac signaling in tumorigenesis

(2011) Natalie A. Mack et al.   CELL CYCLE

Genetic Predisposition Directs Breast Cancer Phenotype by Dictating Progenitor Cell Fate

(2011) Theresa A. Proia et al.   Cell Stem Cell

The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells

(2011) Simone Brabletz et al.   EMBO JOURNAL

miR-126 inhibits proliferation of small cell lung cancer cells by targeting SLC7A5

(2011) Edit Miko et al.   FEBS LETTERS

Recruitment of histone deacetylases HDAC1 and HDAC2 by the transcriptional repressor ZEB1 downregulates E-cadherin expression in pancreatic cancer

(2011) Ali Aghdassi et al.   GUT

Roles for microRNAs in the regulation of cell adhesion molecules

(2011) S. Valastyan et al.   JOURNAL OF CELL SCIENCE

A microRNA-dependent program controls p53-independent survival and chemosensitivity in human and murine squamous cell carcinoma

(2011) Benjamin Ory et al.   JOURNAL OF CLINICAL INVESTIGATION

Systemic Delivery of Tumor Suppressor microRNA Mimics Using a Neutral Lipid Emulsion Inhibits Lung Tumors in Mice

(2011) Phong Trang et al.   MOLECULAR THERAPY

The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44

(2011) Can Liu et al.   NATURE MEDICINE

An integrative genomic approach identifies p73 and p63 as activators of miR-200 microRNA family transcription

(2011) Emily C. Knouf et al.   NUCLEIC ACIDS RESEARCH

MicroRNA-193a represses c-kit expression and functions as a methylation-silenced tumor suppressor in acute myeloid leukemia

(2011) X-N Gao et al.   ONCOGENE

p53 and MicroRNA-34 Are Suppressors of Canonical Wnt Signaling

(2011) N. H. Kim et al.   Science Signaling

The guardians of the genome (p53, TA-p73, and TA-p63) are regulators of tumor suppressor miRNAs network

(2010) Lakshmanane Boominathan   CANCER AND METASTASIS REVIEWS

Development of a Lung Cancer Therapeutic Based on the Tumor Suppressor MicroRNA-34

(2010) J. F. Wiggins et al.   CANCER RESEARCH

ΔNp63 transcriptionally regulatesbrachyury, a gene with diverse roles in limb development, tumorigenesis and metastasis

(2010) Min Soon Cho et al.   CELL CYCLE

The ZEB/miR-200 feedback loop—a motor of cellular plasticity in development and cancer?

(2010) Simone Brabletz et al.   EMBO REPORTS

Robust, Reversible Gene Knockdown Using a Single Lentiviral Short Hairpin RNA Vector

(2010) Cheryl Y. Brown et al.   HUMAN GENE THERAPY

Nanoparticles Modified With Tumor-targeting scFv Deliver siRNA and miRNA for Cancer Therapy

(2010) Yunching Chen et al.   MOLECULAR THERAPY

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs

(2010) Xiaohua Su et al.   NATURE

Bmi1 is essential in Twist1-induced epithelial–mesenchymal transition

(2010) Muh-Hwa Yang et al.   NATURE CELL BIOLOGY

ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1

(2010) E Sánchez-Tilló et al.   ONCOGENE

Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells

(2009) Yohei Shimono et al.   CELL

Focal adhesion kinase: switching between GAPs and GEFs in the regulation of cell motility

(2009) Alok Tomar et al.   CURRENT OPINION IN CELL BIOLOGY

The miR-200 Family: Central Player for Gain and Loss of the Epithelial Phenotype

(2009) Simone Spaderna et al.   GASTROENTEROLOGY

Retinoic Acid Receptor Antagonists Inhibit miR-10a Expression and Block Metastatic Behavior of Pancreatic Cancer

(2009) Frank Ulrich Weiss et al.   GASTROENTEROLOGY

Satb1 and Satb2 regulate embryonic stem cell differentiation andNanogexpression

(2009) Fabio Savarese et al.   GENES & DEVELOPMENT

Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression

(2009) D. L. Gibbons et al.   GENES & DEVELOPMENT

MicroRNA-1/206 Targets c-Metand Inhibits Rhabdomyosarcoma Development

(2009) Dongsheng Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNAs Regulate Human Hepatocyte Nuclear Factor 4α, Modulating the Expression of Metabolic Enzymes and Cell Cycle

(2009) Shingo Takagi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Relapse-Related Molecular Signature in Lung Adenocarcinomas Identifies Patients With Dismal Prognosis

(2009) Shuta Tomida et al.   JOURNAL OF CLINICAL ONCOLOGY

Hypoxia-Inducible mir-210 Regulates Normoxic Gene Expression Involved in Tumor Initiation

(2009) Xin Huang et al.   MOLECULAR CELL

The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

(2009) Ulrich Wellner et al.   NATURE CELL BIOLOGY

An integrated genomic analysis of lung cancer reveals loss of DUSP4 in EGFR-mutant tumors

(2009) D Chitale et al.   ONCOGENE

TGFβ-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3

(2009) B Wang et al.   ONCOGENE

Expression Signatures of Metastatic Capacity in a Genetic Mouse Model of Lung Adenocarcinoma

(2009) Don L. Gibbons et al.   PLoS One

A Double-Negative Feedback Loop between ZEB1-SIP1 and the microRNA-200 Family Regulates Epithelial-Mesenchymal Transition

(2008) C. P. Bracken et al.   CANCER RESEARCH

Assembly and biological role of podosomes and invadopodia

(2008) Mario Gimona et al.   CURRENT OPINION IN CELL BIOLOGY

Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells

(2008) Elisabetta Ferretti et al.   EMBO JOURNAL

A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells

(2008) Ulrike Burk et al.   EMBO REPORTS

Insulin-Like Growth Factor-I Activates Gene Transcription Programs Strongly Associated With Poor Breast Cancer Prognosis

(2008) Chad J. Creighton et al.   JOURNAL OF CLINICAL ONCOLOGY

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY

Collagen I Promotes Epithelial-to-Mesenchymal Transition in Lung Cancer Cells via Transforming Growth Factor–β Signaling

(2007) Yasushi Shintani et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY