Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer

Cancer statistics, 2016

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Genomic analyses identify molecular subtypes of pancreatic cancer

(2016) Peter Bailey et al.   NATURE

Tissue-specific mutation accumulation in human adult stem cells during life

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The genomic landscape and evolution of endometrial carcinoma progression and abdominopelvic metastasis

(2016) William J Gibson et al.   NATURE GENETICS

Identification of neutral tumor evolution across cancer types

(2016) Marc J Williams et al.   NATURE GENETICS

Substantial interindividual and limited intraindividual genomic diversity among tumors from men with metastatic prostate cancer

(2016) Akash Kumar et al.   NATURE MEDICINE

Quantifying Clonal and Subclonal Passenger Mutations in Cancer Evolution

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Reconstruction of clonal trees and tumor composition from multi-sample sequencing data

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The evolutionary history of lethal metastatic prostate cancer

(2015) Gunes Gundem et al.   NATURE

A spatial model predicts that dispersal and cell turnover limit intratumour heterogeneity

(2015) Bartlomiej Waclaw et al.   NATURE

Whole genomes redefine the mutational landscape of pancreatic cancer

(2015) Nicola Waddell et al.   NATURE

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity

(2015) Matthew T Chang et al.   NATURE BIOTECHNOLOGY

The European Genome-phenome Archive of human data consented for biomedical research

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A Big Bang model of human colorectal tumor growth

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Toward understanding and exploiting tumor heterogeneity

(2015) Ash A Alizadeh et al.   NATURE MEDICINE

Subclonal diversification of primary breast cancer revealed by multiregion sequencing

(2015) Lucy R Yates et al.   NATURE MEDICINE

Phylogenetic analyses of melanoma reveal complex patterns of metastatic dissemination

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Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets

(2015) Agnieszka K. Witkiewicz et al.   Nature Communications

Tracking the origins and drivers of subclonal metastatic expansion in prostate cancer

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Pancreatic Cancer Metastases Harbor Evidence of Polyclonality

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Fast and scalable inference of multi-sample cancer lineages

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Adenosquamous carcinoma of the pancreas: Molecular characterization of 23 patients along with a literature review

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Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing

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Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing

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Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

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CRAVAT: cancer-related analysis of variants toolkit

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Cumulative Haploinsufficiency and Triplosensitivity Drive Aneuploidy Patterns and Shape the Cancer Genome

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Genomic and transcriptomic plasticity in treatment-naive ovarian cancer

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Inference of Tumor Phylogenies with Improved Somatic Mutation Discovery

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Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas

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Target inference from collections of genomic intervals

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Half or more of the somatic mutations in cancers of self-renewing tissues originate prior to tumor initiation

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Cancer Genome Landscapes

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Genetic Basis of Pancreas Cancer Development and Progression: Insights from Whole-Exome and Whole-Genome Sequencing

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Secondary mutations inBRCA2associated with clinical resistance to a PARP inhibitor

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Clonal evolution in cancer

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Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

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Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

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Tumour evolution inferred by single-cell sequencing

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Detection and quantification of rare mutations with massively parallel sequencing

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The patterns and dynamics of genomic instability in metastatic pancreatic cancer

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Distant metastasis occurs late during the genetic evolution of pancreatic cancer

(2010) Shinichi Yachida et al.   NATURE

Circos: An information aesthetic for comparative genomics

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Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

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Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing

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Comparative lesion sequencing provides insights into tumor evolution

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Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

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