The Mitochondria–Endoplasmic Reticulum Contacts and Their Critical Role in Aging and Age-Associated Diseases
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Title
The Mitochondria–Endoplasmic Reticulum Contacts and Their Critical Role in Aging and Age-Associated Diseases
Authors
Keywords
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Journal
Frontiers in Cell and Developmental Biology
Volume 7, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-08-21
DOI
10.3389/fcell.2019.00172
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Note: Only part of the references are listed.- SR-mitochondria communication in adult cardiomyocytes: A close relationship where the Ca2+ has a lot to say
- (2019) Sergio De la Fuente et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- PERK-Mediated Unfolded Protein Response Activation and Oxidative Stress in PARK20 Fibroblasts
- (2019) Giuseppina Amodio et al. Frontiers in Neuroscience
- Regulation of mitochondrial bioenergetics by the non-canonical roles of mitochondrial dynamics proteins in the heart
- (2018) Wang Wang et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Targeting the Endoplasmic Reticulum Unfolded Protein Response to Counteract the Oxidative Stress-Induced Endothelial Dysfunction
- (2018) Giuseppina Amodio et al. Oxidative Medicine and Cellular Longevity
- Role of BAG3 in cancer progression: A therapeutic opportunity
- (2018) Margot De Marco et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Alteration of endosomal trafficking is associated with early-onset parkinsonism caused by SYNJ1 mutations
- (2018) Dominga Fasano et al. Cell Death & Disease
- Endoplasmic reticulum and mitochondria in diseases of motor and sensory neurons: a broken relationship?
- (2018) Nathalie Bernard-Marissal et al. Cell Death & Disease
- Mitofusin 2: from functions to disease
- (2018) Riccardo Filadi et al. Cell Death & Disease
- Role of Mitochondria-Associated ER Membranes in Calcium Regulation in Cancer-Specific Settings
- (2018) Giampaolo Morciano et al. NEOPLASIA
- Amyloid-β Peptides are Generated in Mitochondria-Associated Endoplasmic Reticulum Membranes
- (2018) Bernadette Schreiner et al. JOURNAL OF ALZHEIMERS DISEASE
- Combined effect of anti-BAG3 and anti-PD-1 treatment on macrophage infiltrate, CD8 + T cell number and tumour growth in pancreatic cancer
- (2017) Vittoria Iorio et al. GUT
- ER–mitochondria contacts: Actin dynamics at the ER control mitochondrial fission via calcium release
- (2017) Janos Steffen et al. JOURNAL OF CELL BIOLOGY
- INF2-mediated actin polymerization at the ER stimulates mitochondrial calcium uptake, inner membrane constriction, and division
- (2017) Rajarshi Chakrabarti et al. JOURNAL OF CELL BIOLOGY
- Super-resolution optical microscopy for studying membrane structure and dynamics
- (2017) Erdinc Sezgin JOURNAL OF PHYSICS-CONDENSED MATTER
- Mitochondria-Associated Membranes Response to Nutrient Availability and Role in Metabolic Diseases
- (2017) Pierre Theurey et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- ROS Control Mitochondrial Motility through p38 and the Motor Adaptor Miro/Trak
- (2017) Valentina Debattisti et al. Cell Reports
- Proteomic mapping of cytosol-facing outer mitochondrial and ER membranes in living human cells by proximity biotinylation
- (2017) Victoria Hung et al. eLife
- The Endoplasmic Reticulum Unfolded Protein Response in Neurodegenerative Disorders and Its Potential Therapeutic Significance
- (2017) Paolo Remondelli et al. Frontiers in Molecular Neuroscience
- Mitochondria-associated membranes as hubs for neurodegeneration
- (2016) Michiel Krols et al. ACTA NEUROPATHOLOGICA
- Evidence for the involvement of lipid rafts localized at the ER-mitochondria associated membranes in autophagosome formation
- (2016) Tina Garofalo et al. Autophagy
- ER functions of oncogenes and tumor suppressors: Modulators of intracellular Ca 2+ signaling
- (2016) Mart Bittremieux et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- The coming of age of the mitochondria–ER contact: a matter of thickness
- (2016) M Giacomello et al. CELL DEATH AND DIFFERENTIATION
- Mfn2 deficiency links age‐related sarcopenia and impaired autophagy to activation of an adaptive mitophagy pathway
- (2016) David Sebastián et al. EMBO JOURNAL
- MICOS and phospholipid transfer by Ups2–Mdm35 organize membrane lipid synthesis in mitochondria
- (2016) Mari J. Aaltonen et al. JOURNAL OF CELL BIOLOGY
- Calorie restriction as an intervention in ageing
- (2016) Guillermo López-Lluch et al. JOURNAL OF PHYSIOLOGY-LONDON
- Redox Nanodomains Are Induced by and Control Calcium Signaling at the ER-Mitochondrial Interface
- (2016) David M. Booth et al. MOLECULAR CELL
- The Mitochondrial Basis of Aging
- (2016) Nuo Sun et al. MOLECULAR CELL
- Critical reappraisal confirms that Mitofusin 2 is an endoplasmic reticulum–mitochondria tether
- (2016) Deborah Naon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ER-mitochondria contacts couple mtDNA synthesis with mitochondrial division in human cells
- (2016) Samantha C. Lewis et al. SCIENCE
- Mitofusin-mediated ER stress triggers neurodegeneration in pink1/parkin models of Parkinson’s disease
- (2016) I Celardo et al. Cell Death & Disease
- Interplay between hepatic mitochondria-associated membranes, lipid metabolism and caveolin-1 in mice
- (2016) Aleix Sala-Vila et al. Scientific Reports
- Mitochondrial Functional Changes Characterization in Young and Senescent Human Adipose Derived MSCs
- (2016) Bernd R. Stab et al. Frontiers in Aging Neuroscience
- A phospholipid transfer function of ER-mitochondria encounter structure revealed in vitro
- (2016) Rieko Kojima et al. Scientific Reports
- Altered calcium signaling in cancer cells
- (2015) Teneale A. Stewart et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Phosphatidylethanolamine positively regulates autophagy and longevity
- (2015) P Rockenfeller et al. CELL DEATH AND DIFFERENTIATION
- A Role for the Ancient SNARE Syntaxin 17 in Regulating Mitochondrial Division
- (2015) Kohei Arasaki et al. DEVELOPMENTAL CELL
- ApoE4 upregulates the activity of mitochondria-associated ER membranes
- (2015) M. D. Tambini et al. EMBO REPORTS
- Mitochondria-Associated Membrane Formation in Hormone-Stimulated Leydig Cell Steroidogenesis: Role of ATAD3
- (2015) Leeyah Issop et al. ENDOCRINOLOGY
- Analysis of ER-mitochondria contacts using correlative fluorescence microscopy and soft X-ray tomography of mammalian cells
- (2015) K. D. Elgass et al. JOURNAL OF CELL SCIENCE
- Inhibition of SCD1 impairs palmitate-derived autophagy at the step of autophagosome-lysosome fusion in pancreatic β-cells
- (2015) Justyna Janikiewicz et al. JOURNAL OF LIPID RESEARCH
- Mitofusin 2 ablation increases endoplasmic reticulum–mitochondria coupling
- (2015) Riccardo Filadi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness
- (2015) P. Katajisto et al. SCIENCE
- Endoplasmic Reticulum Stress and Oxidative Stress in Cell Fate Decision and Human Disease
- (2014) Stewart Siyan Cao et al. ANTIOXIDANTS & REDOX SIGNALING
- ER-mitochondria contacts as sites of mitophagosome formation
- (2014) Stefan Böckler et al. Autophagy
- Organelle-Based Aggregation and Retention of Damaged Proteins in Asymmetrically Dividing Cells
- (2014) Chuankai Zhou et al. CELL
- Mitochondria Tether Protein Trash to Rejuvenate Cellular Environments
- (2014) Axel Mogk et al. CELL
- Alteration in mitochondrial Ca2+ uptake disrupts insulin signaling in hypertrophic cardiomyocytes
- (2014) Tomás Gutiérrez et al. Cell Communication and Signaling
- Mitochondria-Associated Endoplasmic Reticulum Membrane (MAM) Integrity Is Required for Insulin Signaling and Is Implicated in Hepatic Insulin Resistance
- (2014) E. Tubbs et al. DIABETES
- Stearoyl-CoA Desaturase 1 Activity Is Required for Autophagosome Formation
- (2014) Yuta Ogasawara et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- -Synuclein Is Localized to Mitochondria-Associated ER Membranes
- (2014) C. Guardia-Laguarta et al. JOURNAL OF NEUROSCIENCE
- Chronic enrichment of hepatic endoplasmic reticulum–mitochondria contact leads to mitochondrial dysfunction in obesity
- (2014) Ana Paula Arruda et al. NATURE MEDICINE
- Cellular mechanisms and physiological consequences of redox-dependent signalling
- (2014) Kira M. Holmström et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Metabolic syndrome: a closer look at the growing epidemic and its associated pathologies
- (2014) S. O'Neill et al. Obesity Reviews
- Genetically enhancing mitochondrial antioxidant activity improves muscle function in aging
- (2014) Alisa Umanskaya et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Mitofusin-2–dependent inactivating cleavage of Opa1 links changes in mitochondriacristaeand ER contacts in the postprandial liver
- (2014) Aditi Sood et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43
- (2014) Radu Stoica et al. Nature Communications
- PGC1α-mediated Mitofusin-2 Deficiency in Female Rats and Humans with Pulmonary Arterial Hypertension
- (2013) John J. Ryan et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- MAM (mitochondria-associated membranes) in mammalian cells: Lipids and beyond
- (2013) Jean E. Vance BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Enhanced parkin levels favor ER-mitochondria crosstalk and guarantee Ca2+ transfer to sustain cell bioenergetics
- (2013) Tito Calì et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Mitofusin 2 in POMC Neurons Connects ER Stress with Leptin Resistance and Energy Imbalance
- (2013) Marc Schneeberger et al. CELL
- Identification of PTEN at the ER and MAMs and its regulation of Ca2+ signaling and apoptosis in a protein phosphatase-dependent manner
- (2013) A Bononi et al. CELL DEATH AND DIFFERENTIATION
- Cardiolipin remodeling in diabetic heart
- (2013) Quan He et al. CHEMISTRY AND PHYSICS OF LIPIDS
- -Cell Dysfunction Due to Increased ER Stress in a Stem Cell Model of Wolfram Syndrome
- (2013) L. Shang et al. DIABETES
- Mfn2 modulates the UPR and mitochondrial function via repression of PERK
- (2013) Juan Pablo Muñoz et al. EMBO JOURNAL
- The Parkinson disease-related protein DJ-1 counteracts mitochondrial impairment induced by the tumour suppressor protein p53 by enhancing endoplasmic reticulum-mitochondria tethering
- (2013) D. Ottolini et al. HUMAN MOLECULAR GENETICS
- In-depth proteomic analysis of mammalian mitochondria-associated membranes (MAM)
- (2013) Chloe N. Poston et al. Journal of Proteomics
- Protein carbonylation: Proteomics, specificity and relevance to aging
- (2013) Elisa Cabiscol et al. MASS SPECTROMETRY REVIEWS
- Autophagosomes form at ER–mitochondria contact sites
- (2013) Maho Hamasaki et al. NATURE
- Suppression of eIF2α kinases alleviates Alzheimer's disease–related plasticity and memory deficits
- (2013) Tao Ma et al. NATURE NEUROSCIENCE
- Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy
- (2013) Chia-Chen Liu et al. Nature Reviews Neurology
- Dysregulation of Mitochondrial Quality Control Processes Contribute to Sarcopenia in a Mouse Model of Premature Aging
- (2013) Anna-Maria Joseph et al. PLoS One
- Sigma-1 Receptor Chaperone at the ER-Mitochondrion Interface Mediates the Mitochondrion-ER-Nucleus Signaling for Cellular Survival
- (2013) Tomohisa Mori et al. PLoS One
- Modulation of the endoplasmic reticulum-mitochondria interface in Alzheimer's disease and related models
- (2013) L. Hedskog et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Actin-Dependent Step in Mitochondrial Fission Mediated by the ER-Associated Formin INF2
- (2013) F. Korobova et al. SCIENCE
- PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for Culling Damaged Mitochondria
- (2013) Y. Chen et al. SCIENCE
- Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice
- (2013) J. A. Moreno et al. Science Translational Medicine
- Lipid Transport between the Endoplasmic Reticulum and Mitochondria
- (2013) V. V. Flis et al. Cold Spring Harbor Perspectives in Biology
- ER-associated mitochondrial division links the distribution of mitochondria and mitochondrial DNA in yeast
- (2013) Andrew Murley et al. eLife
- PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress
- (2012) T Verfaillie et al. CELL DEATH AND DIFFERENTIATION
- α-Synuclein Controls Mitochondrial Calcium Homeostasis by Enhancing Endoplasmic Reticulum-Mitochondria Interactions
- (2012) Tito Calì et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondria-associated ER membranes in Alzheimer disease
- (2012) Eric A. Schon et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Endoplasmic reticulum–mitochondria contacts: function of the junction
- (2012) Ashley A. Rowland et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mitofusin-2 Independent Juxtaposition of Endoplasmic Reticulum and Mitochondria: An Ultrastructural Study
- (2012) Pierre Cosson et al. PLoS One
- Ero1α Regulates Ca2+ Fluxes at the Endoplasmic Reticulum–Mitochondria Interface (MAM)
- (2011) Tiziana Anelli et al. ANTIOXIDANTS & REDOX SIGNALING
- The role of cholesterol in the association of endoplasmic reticulum membranes with mitochondria
- (2011) Michiko Fujimoto et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Glucose metabolism and cardiac hypertrophy
- (2011) S. C. Kolwicz et al. CARDIOVASCULAR RESEARCH
- Autophagy and Aging
- (2011) David C. Rubinsztein et al. CELL
- Ryanodine Receptor Oxidation Causes Intracellular Calcium Leak and Muscle Weakness in Aging
- (2011) Daniel C. Andersson et al. Cell Metabolism
- Proteomic Signatures in Thapsigargin-Treated Hepatoma Cells
- (2011) Giuseppina Amodio et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Organelle Dynamics: ER Embraces Mitochondria for Fission
- (2011) Benedikt Westermann CURRENT BIOLOGY
- Caveolin-1 Deficiency Causes Cholesterol-Dependent Mitochondrial Dysfunction and Apoptotic Susceptibility
- (2011) Marta Bosch et al. CURRENT BIOLOGY
- VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis
- (2011) Kurt J. De Vos et al. HUMAN MOLECULAR GENETICS
- There is no evidence that mitochondria are the main source of reactive oxygen species in mammalian cells
- (2011) Guy C. Brown et al. MITOCHONDRION
- Presenilin 2 modulates endoplasmic reticulum (ER)-mitochondria interactions and Ca2+ cross-talk
- (2011) E. Zampese et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ER Tubules Mark Sites of Mitochondrial Division
- (2011) J. R. Friedman et al. SCIENCE
- The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
- (2011) P. Walter et al. SCIENCE
- The complexity of cardiolipin in health and disease
- (2011) Steven M. Claypool et al. TRENDS IN BIOCHEMICAL SCIENCES
- Ero1α requires oxidizing and normoxic conditions to localize to the mitochondria-associated membrane (MAM)
- (2010) Susanna Y. Gilady et al. CELL STRESS & CHAPERONES
- Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction
- (2010) Ryota Iwasawa et al. EMBO JOURNAL
- Detergent-Resistant Microdomains Determine the Localization of -1 Receptors to the Endoplasmic Reticulum-Mitochondria Junction
- (2010) T. Hayashi et al. MOLECULAR PHARMACOLOGY
- A role for mitochondria in NLRP3 inflammasome activation
- (2010) Rongbin Zhou et al. NATURE
- Mitochondrial fusion and fission in cell life and death
- (2010) Benedikt Westermann NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Presenilins Are Enriched in Endoplasmic Reticulum Membranes Associated with Mitochondria
- (2009) Estela Area-Gomez et al. AMERICAN JOURNAL OF PATHOLOGY
- Age-related changes in levels of p66Shc and serine 36-phosphorylated p66Shc in organs and mouse tissues
- (2009) M. Lebiedzinska et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Role of ERO1-α–mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress–induced apoptosis
- (2009) Gang Li et al. JOURNAL OF CELL BIOLOGY
- Mitochondrial fusion, fission and autophagy as a quality control axis: The bioenergetic view
- (2008) Gilad Twig et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- VAPB interacts with and modulates the activity of ATF6
- (2008) C. Gkogkas et al. HUMAN MOLECULAR GENETICS
- Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
- (2008) Elizabeth L. Axe et al. JOURNAL OF CELL BIOLOGY
- Mitochondrial dysfunction in rat brain with agingInvolvement of complex I, reactive oxygen species and cardiolipin
- (2008) G PETROSILLO et al. NEUROCHEMISTRY INTERNATIONAL
- Decreased enzyme activities of chaperones PDI and BiP in aged mouse livers
- (2007) Jonathan E. Nuss et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Fatty Acid Profile of Erythrocyte Membranes As Possible Biomarker of Longevity
- (2007) Annibale A. Puca et al. REJUVENATION RESEARCH
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