Endoplasmic reticulum and mitochondria in diseases of motor and sensory neurons: a broken relationship?
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Endoplasmic reticulum and mitochondria in diseases of motor and sensory neurons: a broken relationship?
Authors
Keywords
-
Journal
Cell Death & Disease
Volume 9, Issue 3, Pages -
Publisher
Springer Nature
Online
2018-02-28
DOI
10.1038/s41419-017-0125-1
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Peroxynitrite Activates the NLRP3 Inflammasome Cascade in SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis
- (2017) Ilaria Bellezza et al. MOLECULAR NEUROBIOLOGY
- Neurobiology of axonal transport defects in motor neuron diseases: Opportunities for translational research?
- (2017) Kurt J. De Vos et al. NEUROBIOLOGY OF DISEASE
- Sigma 1 receptor activation modifies intracellular calcium exchange in the G93A hSOD1 ALS model
- (2017) Vedrana Tadić et al. NEUROSCIENCE
- The ER proteostasis network in ALS: Determining the differential motoneuron vulnerability
- (2017) Pablo Rozas et al. NEUROSCIENCE LETTERS
- Autophagy as an Emerging Common Pathomechanism in Inherited Peripheral Neuropathies
- (2017) Mansour Haidar et al. Frontiers in Molecular Neuroscience
- Autophagy Dysregulation in ALS: When Protein Aggregates Get Out of Hand
- (2017) Nandini Ramesh et al. Frontiers in Molecular Neuroscience
- Impaired Mitophagy Plays a Role in Denervation of Neuromuscular Junctions in ALS Mice
- (2017) Robert S. Rogers et al. Frontiers in Neuroscience
- CMT-linked loss-of-function mutations in GDAP1 impair store-operated Ca2+ entry-stimulated respiration
- (2017) Paloma González-Sánchez et al. Scientific Reports
- Mitochondria-associated membranes as hubs for neurodegeneration
- (2016) Michiel Krols et al. ACTA NEUROPATHOLOGICA
- Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways
- (2016) Anna M. Blokhuis et al. ACTA NEUROPATHOLOGICA
- A novel de novo dominant negative mutation inDNM1Limpairs mitochondrial fission and presents as childhood epileptic encephalopathy
- (2016) Jill A. Fahrner et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- The role of endoplasmic reticulum stress in neurodegenerative disease
- (2016) Chunchen Xiang et al. APOPTOSIS
- Evidence for the involvement of lipid rafts localized at the ER-mitochondria associated membranes in autophagosome formation
- (2016) Tina Garofalo et al. Autophagy
- ALS: Recent Developments from Genetics Studies
- (2016) Martine Therrien et al. Current Neurology and Neuroscience Reports
- Mitochondria‐associated membrane collapse is a common pathomechanism in SIGMAR1 ‐ and SOD1 ‐linked ALS
- (2016) Seiji Watanabe et al. EMBO Molecular Medicine
- ALS/FTD‐associated FUS activates GSK‐3β to disrupt the VAPB–PTPIP51 interaction and ER–mitochondria associations
- (2016) Radu Stoica et al. EMBO REPORTS
- Selective mitochondrial depletion, apoptosis resistance, and increased mitophagy in human Charcot-Marie-Tooth 2A motor neurons
- (2016) Federica Rizzo et al. HUMAN MOLECULAR GENETICS
- Loss-of-function mutations in theSIGMAR1gene cause distal hereditary motor neuropathy by impairing ER-mitochondria tethering and Ca2+signalling
- (2016) Elisa Gregianin et al. HUMAN MOLECULAR GENETICS
- Decoding ALS: from genes to mechanism
- (2016) J. Paul Taylor et al. NATURE
- The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity
- (2016) Wenzhang Wang et al. NATURE MEDICINE
- Mitochondria and endoplasmic reticulum crosstalk in amyotrophic lateral sclerosis
- (2016) Giovanni Manfredi et al. NEUROBIOLOGY OF DISEASE
- Critical reappraisal confirms that Mitofusin 2 is an endoplasmic reticulum–mitochondria tether
- (2016) Deborah Naon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- There's Something Wrong with my MAM; the ER–Mitochondria Axis and Neurodegenerative Diseases
- (2016) Sebastien Paillusson et al. TRENDS IN NEUROSCIENCES
- Impaired Autophagy and Defective Mitochondrial Function: Converging Paths on the Road to Motor Neuron Degeneration
- (2016) Brittany M. Edens et al. Frontiers in Cellular Neuroscience
- Mitochondria-Associated Membranes: Composition, Molecular Mechanisms, and Physiopathological Implications
- (2015) Carlotta Giorgi et al. ANTIOXIDANTS & REDOX SIGNALING
- Dysfunction in endoplasmic reticulum-mitochondria crosstalk underlies SIGMAR1 loss of function mediated motor neuron degeneration
- (2015) Nathalie Bernard-Marissal et al. BRAIN
- Axonal Charcot–Marie–Tooth disease patient-derived motor neurons demonstrate disease-specific phenotypes including abnormal electrophysiological properties
- (2015) Mario A. Saporta et al. EXPERIMENTAL NEUROLOGY
- NLRP3 inflammasome is expressed by astrocytes in the SOD1 mouse model of ALS and in human sporadic ALS patients
- (2015) Sonja Johann et al. GLIA
- The Role of Mitochondrially Derived ATP in Synaptic Vesicle Recycling
- (2015) Divya Pathak et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Distinct mechanisms controlling rough and smooth endoplasmic reticulum contacts with mitochondria
- (2015) P. T. C. Wang et al. JOURNAL OF CELL SCIENCE
- Distribution of Monocarboxylate Transporters in the Peripheral Nervous System Suggests Putative Roles in Lactate Shuttling and Myelination
- (2015) E. Domenech-Estevez et al. JOURNAL OF NEUROSCIENCE
- Role of sigma-1 receptors in neurodegenerative diseases
- (2015) Linda Nguyen et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Marinesco-Sjögren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS
- (2015) Audrey Filézac de L'Etang et al. NATURE NEUROSCIENCE
- Calreticulin levels determine onset of early muscle denervation by fast motoneurons of ALS model mice
- (2015) Nathalie Bernard-Marissal et al. NEUROBIOLOGY OF DISEASE
- In silico analysis of SIGMAR1 variant (rs4879809) segregating in a consanguineous Pakistani family showing amyotrophic lateral sclerosis without frontotemporal lobar dementia
- (2015) Muhammad Ikram Ullah et al. NEUROGENETICS
- A SIGMAR1 splice-site mutation causes distal hereditary motor neuropathy
- (2015) X. Li et al. NEUROLOGY
- Mitofusin 2 ablation increases endoplasmic reticulum–mitochondria coupling
- (2015) Riccardo Filadi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- p53 at the endoplasmic reticulum regulates apoptosis in a Ca2+-dependent manner
- (2015) Carlotta Giorgi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lack of GDAP1 Induces Neuronal Calcium and Mitochondrial Defects in a Knockout Mouse Model of Charcot-Marie-Tooth Neuropathy
- (2015) Manuela Barneo-Muñoz et al. PLoS Genetics
- New functions of mitochondria associated membranes in cellular signaling
- (2014) Alexander R. van Vliet et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Neuronal calcium signaling: function and dysfunction
- (2014) Marisa Brini et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Glial cells in amyotrophic lateral sclerosis
- (2014) T. Philips et al. EXPERIMENTAL NEUROLOGY
- Calcium Release from Intra-Axonal Endoplasmic Reticulum Leads to Axon Degeneration through Mitochondrial Dysfunction
- (2014) R. Villegas et al. JOURNAL OF NEUROSCIENCE
- FUS is Phosphorylated by DNA-PK and Accumulates in the Cytoplasm after DNA Damage
- (2014) Q. Deng et al. JOURNAL OF NEUROSCIENCE
- Hereditary motor and sensory neuropathies or Charcot–Marie–Tooth diseases: An update
- (2014) Meriem Tazir et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Characterization of the mitofusin 2 R94W mutation in a knock-in mouse model
- (2014) Alleene V. Strickland et al. JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM
- A Computational Model of Motor Neuron Degeneration
- (2014) Gwendal Le Masson et al. NEURON
- Axonal Transport: Cargo-Specific Mechanisms of Motility and Regulation
- (2014) Sandra Maday et al. NEURON
- The ER mitochondria calcium cycle and ER stress response as therapeutic targets in amyotrophic lateral sclerosis
- (2014) Vedrana Tadic et al. Frontiers in Cellular Neuroscience
- Loss of function of the ALS protein SigR1 leads to ER pathology associated with defective autophagy and lipid raft disturbances
- (2014) J T Vollrath et al. Cell Death & Disease
- MAM (mitochondria-associated membranes) in mammalian cells: Lipids and beyond
- (2013) Jean E. Vance BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Calcium-dependent protein folding in amyotrophic lateral sclerosis
- (2013) Tino Prell et al. CELL CALCIUM
- Identification of PTEN at the ER and MAMs and its regulation of Ca2+ signaling and apoptosis in a protein phosphatase-dependent manner
- (2013) A Bononi et al. CELL DEATH AND DIFFERENTIATION
- Calcium and Endoplasmic Reticulum-Mitochondria Tethering in Neurodegeneration
- (2013) Tito Calì et al. DNA AND CELL BIOLOGY
- Mfn2 modulates the UPR and mitochondrial function via repression of PERK
- (2013) Juan Pablo Muñoz et al. EMBO JOURNAL
- Altered localization, abnormal modification and loss of function of Sigma receptor-1 in amyotrophic lateral sclerosis
- (2013) J. Prause et al. HUMAN MOLECULAR GENETICS
- In-depth proteomic analysis of mammalian mitochondria-associated membranes (MAM)
- (2013) Chloe N. Poston et al. Journal of Proteomics
- Autophagosomes form at ER–mitochondria contact sites
- (2013) Maho Hamasaki et al. NATURE
- Clinical implications of genetic advances in Charcot–Marie–Tooth disease
- (2013) Alexander M. Rossor et al. Nature Reviews Neurology
- Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084, in a mouse model of motor neuron disease not linked to SOD1 mutation
- (2013) Marco Peviani et al. NEUROBIOLOGY OF DISEASE
- Mitochondrial impairment increases FL-PINK1 levels by calcium-dependent gene expression
- (2013) Rubén Gómez-Sánchez et al. NEUROBIOLOGY OF DISEASE
- Aberrant Schwann Cell Lipid Metabolism Linked to Mitochondrial Deficits Leads to Axon Degeneration and Neuropathy
- (2013) Andreu Viader et al. NEURON
- Converging Mechanisms in ALS and FTD: Disrupted RNA and Protein Homeostasis
- (2013) Shuo-Chien Ling et al. NEURON
- Modulation of the endoplasmic reticulum-mitochondria interface in Alzheimer's disease and related models
- (2013) L. Hedskog et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Actin-Dependent Step in Mitochondrial Fission Mediated by the ER-Associated Formin INF2
- (2013) F. Korobova et al. SCIENCE
- Neuronal activity in the hub of extrasynaptic Schwann cell-axon interactions
- (2013) Chrysanthi Samara et al. Frontiers in Cellular Neuroscience
- Peripheral nerve axons contain machinery for co-translational secretion of axonally-generated proteins
- (2013) Tanuja Merianda et al. Neuroscience Bulletin
- The genetics and neuropathology of amyotrophic lateral sclerosis
- (2012) Ammar Al-Chalabi et al. ACTA NEUROPATHOLOGICA
- Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion
- (2012) Jacqueline C. Mitchell et al. ACTA NEUROPATHOLOGICA
- Neuronal overexpression of IP3 receptor 2 is detrimental in mutant SOD1 mice
- (2012) Kim A. Staats et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress
- (2012) T Verfaillie et al. CELL DEATH AND DIFFERENTIATION
- The role of myelin oligodendrocyte glycoprotein in autoimmune demyelination: a target for multiple sclerosis therapy?
- (2012) De-Hyung Lee et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Amyotrophic lateral sclerosis-associated mutant VAPBP56S perturbs calcium homeostasis to disrupt axonal transport of mitochondria
- (2012) G. M. Morotz et al. HUMAN MOLECULAR GENETICS
- Loss of Mfn2 results in progressive, retrograde degeneration of dopaminergic neurons in the nigrostriatal circuit
- (2012) Anh H. Pham et al. HUMAN MOLECULAR GENETICS
- The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth
- (2012) Claudia Fallini et al. HUMAN MOLECULAR GENETICS
- Mitofusin2 Mutations Disrupt Axonal Mitochondrial Positioning and Promote Axon Degeneration
- (2012) A. L. Misko et al. JOURNAL OF NEUROSCIENCE
- Reduced Calreticulin Levels Link Endoplasmic Reticulum Stress and Fas-Triggered Cell Death in Motoneurons Vulnerable to ALS
- (2012) N. Bernard-Marissal et al. JOURNAL OF NEUROSCIENCE
- Mitochondria-associated ER membranes in Alzheimer disease
- (2012) Eric A. Schon et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs
- (2012) Clotilde Lagier-Tourenne et al. NATURE NEUROSCIENCE
- Sigma-1R Agonist Improves Motor Function and Motoneuron Survival in ALS Mice
- (2012) Renzo Mancuso et al. Neurotherapeutics
- Mitofusin-2 Independent Juxtaposition of Endoplasmic Reticulum and Mitochondria: An Ultrastructural Study
- (2012) Pierre Cosson et al. PLoS One
- A mutation in sigma-1 receptor causes juvenile amyotrophic lateral sclerosis
- (2011) Amr Al-Saif et al. ANNALS OF NEUROLOGY
- SQSTM1 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
- (2011) Faisal Fecto ARCHIVES OF NEUROLOGY
- Mitochondrial dysfunction induced by knockdown of mortalin is rescued by Parkin
- (2011) Hui Yang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Phosphatase and tensin homologue/protein kinase B pathway linked to motor neuron survival in human superoxide dismutase 1-related amyotrophic lateral sclerosis
- (2011) Janine Kirby et al. BRAIN
- Functional genomic screen and network analysis reveal novel modifiers of tauopathy dissociated from tau phosphorylation
- (2011) Surendra S. Ambegaokar et al. HUMAN MOLECULAR GENETICS
- VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis
- (2011) Kurt J. De Vos et al. HUMAN MOLECULAR GENETICS
- Myelination and Axonal Electrical Activity Modulate the Distribution and Motility of Mitochondria at CNS Nodes of Ranvier
- (2011) N. Ohno et al. JOURNAL OF NEUROSCIENCE
- Mutations in INF2 Are a Major Cause of Autosomal Dominant Focal Segmental Glomerulosclerosis
- (2011) O. Boyer et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia
- (2011) Han-Xiang Deng et al. NATURE
- VCP mutations in familial and sporadic amyotrophic lateral sclerosis
- (2011) Max Koppers et al. NEUROBIOLOGY OF AGING
- MFN2 mutations cause severe phenotypes in most patients with CMT2A
- (2011) S. M. E. Feely et al. NEUROLOGY
- Review: The role of mitochondria in the pathogenesis of amyotrophic lateral sclerosis
- (2011) L. M. Duffy et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- ER Tubules Mark Sites of Mitochondrial Division
- (2011) J. R. Friedman et al. SCIENCE
- How could Parkin-mediated ubiquitination of mitofusin promote mitophagy?
- (2010) Elena Ziviani et al. Autophagy
- Oxidative protein folding in the endoplasmic reticulum: Tight links to the mitochondria-associated membrane (MAM)
- (2010) Thomas Simmen et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Expression of mitofusin 2R94Q in a transgenic mouse leads to Charcot–Marie–Tooth neuropathy type 2A
- (2010) Romain Cartoni et al. BRAIN
- Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration
- (2010) Agnes L. Nishimura et al. BRAIN
- Calcium dysregulation in amyotrophic lateral sclerosis
- (2010) Julian Grosskreutz et al. CELL CALCIUM
- Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction
- (2010) Ryota Iwasawa et al. EMBO JOURNAL
- Lipid metabolism in myelinating glial cells: lessons from human inherited disorders and mouse models
- (2010) Roman Chrast et al. JOURNAL OF LIPID RESEARCH
- AAV-mediated expression of wild-type and ALS-linked mutant VAPB selectively triggers death of motoneurons through a Ca2+-dependent ER-associated pathway
- (2010) Karine Langou et al. JOURNAL OF NEUROCHEMISTRY
- Mitofusin 2 Is Necessary for Transport of Axonal Mitochondria and Interacts with the Miro/Milton Complex
- (2010) A. Misko et al. JOURNAL OF NEUROSCIENCE
- Phenotypical features of the p.R120W mutation in the GDAP1 gene causing autosomal dominant Charcot-Marie-Tooth disease
- (2010) Rafael Sivera et al. JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM
- Detergent-Resistant Microdomains Determine the Localization of -1 Receptors to the Endoplasmic Reticulum-Mitochondria Junction
- (2010) T. Hayashi et al. MOLECULAR PHARMACOLOGY
- A role for mitochondria in NLRP3 inflammasome activation
- (2010) Rongbin Zhou et al. NATURE
- Mutations of optineurin in amyotrophic lateral sclerosis
- (2010) Hirofumi Maruyama et al. NATURE
- Misfolded Mutant SOD1 Directly Inhibits VDAC1 Conductance in a Mouse Model of Inherited ALS
- (2010) Adrian Israelson et al. NEURON
- Deficits in axonal transport precede ALS symptoms in vivo
- (2010) L. G. Bilsland et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rethinking ALS: The FUS about TDP-43
- (2009) Clotilde Lagier-Tourenne et al. CELL
- The Mechanism of Ca2+-Dependent Regulation of Kinesin-Mediated Mitochondrial Motility
- (2009) Xinnan Wang et al. CELL
- Role of mitofusin 2 mutations in the physiopathology of Charcot–Marie–Tooth disease type 2A
- (2009) Romain Cartoni et al. EXPERIMENTAL NEUROLOGY
- Astrocyte function and role in motor neuron disease: A future therapeutic target?
- (2009) Daniel Blackburn et al. GLIA
- Mitofusin-2 regulates mitochondrial and endoplasmic reticulum morphology and tethering: The role of Ras
- (2009) Olga Martins de Brito et al. MITOCHONDRION
- A role for motoneuron subtype–selective ER stress in disease manifestations of FALS mice
- (2009) Smita Saxena et al. NATURE NEUROSCIENCE
- Isolation of mitochondria-associated membranes and mitochondria from animal tissues and cells
- (2009) Mariusz R Wieckowski et al. Nature Protocols
- Analysis of FUS gene mutation in familial amyotrophic lateral sclerosis within an Italian cohort
- (2009) N. Ticozzi et al. NEUROLOGY
- Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis
- (2009) T. J. Kwiatkowski et al. SCIENCE
- MAM: more than just a housekeeper
- (2009) Teruo Hayashi et al. TRENDS IN CELL BIOLOGY
- VAPB interacts with and modulates the activity of ATF6
- (2008) C. Gkogkas et al. HUMAN MOLECULAR GENETICS
- Mitofusin 2 tethers endoplasmic reticulum to mitochondria
- (2008) Olga Martins de Brito et al. NATURE
- Bidirectional Ca2+-dependent control of mitochondrial dynamics by the Miro GTPase
- (2008) M. Saotome et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started