C-type lectin receptor-mediated immune recognition and response of the microbiota in the gut

Dectin-2 Is a C-Type Lectin Receptor that Recognizes Pneumocystis and Participates in Innate Immune Responses

(2018) Theodore J. Kottom et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

IL-23 and IL-1β Drive Human Th17 Cell Differentiation and Metabolic Reprogramming in Absence of CD28 Costimulation

(2018) Shankar Revu et al.   Cell Reports

The Syk-Coupled C-Type Lectin Receptors Dectin-2 and Dectin-3 Are Involved in Paracoccidioides brasiliensis Recognition by Human Plasmacytoid Dendritic Cells

(2018) Nycolas Willian Preite et al.   Frontiers in Immunology

The Interaction of Human Pathogenic Fungi With C-Type Lectin Receptors

(2018) Surabhi Goyal et al.   Frontiers in Immunology

Human Gut Microbiota and Gastrointestinal Cancer

(2018) Changting Meng et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

The Adaptor Protein CARD9 Protects against Colon Cancer by Restricting Mycobiota-Mediated Expansion of Myeloid-Derived Suppressor Cells

(2018) Tingting Wang et al.   IMMUNITY

SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer

(2018) Ankit Malik et al.   IMMUNITY

Dysbiosis signature of mycobiota in colon polyp and colorectal cancer

(2017) R. Gao et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Roles for Intestinal Bacteria, Viruses, and Fungi in Pathogenesis of Inflammatory Bowel Diseases and Therapeutic Approaches

(2017) R. Balfour Sartor et al.   GASTROENTEROLOGY

Homeostatic Immunity and the Microbiota

(2017) Yasmine Belkaid et al.   IMMUNITY

The Interaction ofPneumocystiswith the C-Type Lectin Receptor Mincle Exerts a Significant Role in Host Defense against Infection

(2017) Theodore J. Kottom et al.   JOURNAL OF IMMUNOLOGY

Fungi in Gastrointestinal Tracts of Human and Mice: from Community to Functions

(2017) Jiayan Li et al.   MICROBIAL ECOLOGY

Candida albicans infection and intestinal immunity

(2017) Yiqing Tong et al.   MICROBIOLOGICAL RESEARCH

The Expression of Dectin-1, Irak1 and Rip2 During the Host Response to Aspergillus fumigatus

(2017) Jinguo Liu et al.   MYCOPATHOLOGIA

Gut microbiota and IBD: causation or correlation?

(2017) Josephine Ni et al.   Nature Reviews Gastroenterology & Hepatology

A role for bacterial urease in gut dysbiosis and Crohn’s disease

(2017) Josephine Ni et al.   Science Translational Medicine

Microbiota as a mediator of cancer progression and therapy

(2017) Jillian L. Pope et al.   Translational Research

The gut microbiota and inflammatory bowel diseases

(2017) Jun Miyoshi et al.   Translational Research

Dectin-2 is a primary receptor for NLRP3 inflammasome activation in dendritic cell response to Histoplasma capsulatum

(2017) Tzu-Hsuan Chang et al.   PLoS Pathogens

The C-Type Lectin Mincle: Clues for a Role in Crohn’s Disease Adjuvant Reaction

(2017) Anje A. te Velde   Frontiers in Immunology

Sensing Lipids with Mincle: Structure and Function

(2017) Spencer J. Williams   Frontiers in Immunology

Dectin-3 Is Not Required for Protection against Cryptococcus neoformans Infection

(2017) Althea Campuzano et al.   PLoS One

Immunological Consequences of Intestinal Fungal Dysbiosis

(2016) Matthew L. Wheeler et al.   Cell Host & Microbe

Fungal microbiota dysbiosis in IBD

(2016) Harry Sokol et al.   GUT

Antifungal Activity of Plasmacytoid Dendritic Cells against Cryptococcus neoformansIn VitroRequires Expression of Dectin-3 (CLEC4D) and Reactive Oxygen Species

(2016) Camaron R. Hole et al.   INFECTION AND IMMUNITY

Dectin-1 Controls TLR9 Trafficking to Phagosomes Containing β-1,3 Glucan

(2016) Nida S. Khan et al.   JOURNAL OF IMMUNOLOGY

The Role of Dectin-2 for Host Defense Against Disseminated Candidiasis

(2016) Daniela C. Ifrim et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Fungi in the healthy human gastrointestinal tract

(2016) Heather E. Hallen-Adams et al.   Virulence

Dectin-3 Deficiency Promotes Colitis Development due to Impaired Antifungal Innate Immune Responses in the Gut

(2016) Tingting Wang et al.   PLoS Pathogens

Age and Gender Affect the Composition of Fungal Population of the Human Gastrointestinal Tract

(2016) Francesco Strati et al.   Frontiers in Microbiology

Vasoactive Intestinal Peptide modulates trophoblast-derived cell line function and interaction with phagocytic cells through autocrine pathways

(2016) Daiana Vota et al.   Scientific Reports

Dectin-1 Exerts Dual Control in the Gut

(2015) Iliyan D. Iliev   Cell Host & Microbe

Inhibition of Dectin-1 Signaling Ameliorates Colitis by Inducing Lactobacillus-Mediated Regulatory T Cell Expansion in the Intestine

(2015) Ce Tang et al.   Cell Host & Microbe

Inflammation, Antibiotics, and Diet as Environmental Stressors of the Gut Microbiome in Pediatric Crohn’s Disease

(2015) James D. Lewis et al.   Cell Host & Microbe

Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism

(2015) Fiona Cuskin et al.   NATURE

Activation of HIF-1α and LL-37 by commensal bacteria inhibits Candida albicans colonization

(2015) Di Fan et al.   NATURE MEDICINE

Cancer and the gut microbiota: An unexpected link

(2015) Laurence Zitvogel et al.   Science Translational Medicine

The role of pattern recognition receptors in the innate recognition ofCandida albicans

(2015) Nan-Xin Zheng et al.   Virulence

Dectin-1 Regulates Hepatic Fibrosis and Hepatocarcinogenesis by Suppressing TLR4 Signaling Pathways

(2015) Lena Seifert et al.   Cell Reports

Intestinal Microbiota and the Innate Immune System – A Crosstalk in Crohn’s Disease Pathogenesis

(2015) Lea-Maxie Haag et al.   Frontiers in Immunology

Microbiome, Inflammation, and Cancer

(2014) Ralph Francescone et al.   CANCER JOURNAL

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

Fungal Engagement of the C-Type Lectin Mincle Suppresses Dectin-1-Induced Antifungal Immunity

(2014) Brigitte A. Wevers et al.   Cell Host & Microbe

Inflammatory Bowel Disease Cause-specific Mortality

(2014) Zain Kassam et al.   INFLAMMATORY BOWEL DISEASES

Dectin-1-mediated Signaling Leads to Characteristic Gene Expressions and Cytokine Secretion via Spleen Tyrosine Kinase (Syk) in Rat Mast Cells

(2014) Yukihiro Kimura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

C-type Lectin Receptor Dectin-3 Mediates Trehalose 6,6′-Dimycolate (TDM)-induced Mincle Expression through CARD9/Bcl10/MALT1-dependent Nuclear Factor (NF)-κB Activation

(2014) Xue-Qiang Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caspase-8 Modulates Dectin-1 and Complement Receptor 3–Driven IL-1β Production in Response to β-Glucans and the Fungal Pathogen,Candida albicans

(2014) Sandhya Ganesan et al.   JOURNAL OF IMMUNOLOGY

The WNT Signaling Pathway Contributes to Dectin-1-Dependent Inhibition of Toll-Like Receptor-Induced Inflammatory Signature

(2014) J. Trinath et al.   MOLECULAR AND CELLULAR BIOLOGY

Role of the C-Type Lectin Receptors MCL and DCIR in Experimental Colitis

(2014) Julia Hütter et al.   PLoS One

Surface area of the digestive tract – revisited

(2014) Herbert F Helander et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Antifungal innate immunity: recognition and inflammatory networks

(2014) Katharina L. Becker et al.   Seminars in Immunopathology

Inflammation and colorectal cancer, when microbiota-host mutualism breaks

(2014) Marco Candela   WORLD JOURNAL OF GASTROENTEROLOGY

Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses

(2014) Shiho Chiba et al.   eLife

The Intestinal Microbiome in Early Life: Health and Disease

(2014) Marie-Claire Arrieta et al.   Frontiers in Immunology

Dectin-2 is predominately macrophage restricted and exhibits conspicuous expression during Aspergillus fumigatus invasion in human lung

(2013) He Sun et al.   CELLULAR IMMUNOLOGY

C-Type Lectin Receptors Dectin-3 and Dectin-2 Form a Heterodimeric Pattern-Recognition Receptor for Host Defense against Fungal Infection

(2013) Le-Le Zhu et al.   IMMUNITY

C-Type Lectin-Like Receptors of the Dectin-1 Cluster: Ligands and Signaling Pathways

(2013) Anthony Plato et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Dysbiosis of Gut Fungal Microbiota is Associated With Mucosal Inflammation in Crohn’s Disease

(2013) Qiurong Li et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Microfold (M) cells: important immunosurveillance posts in the intestinal epithelium

(2013) N A Mabbott et al.   Mucosal Immunology

The gut microbiota — masters of host development and physiology

(2013) Felix Sommer et al.   NATURE REVIEWS MICROBIOLOGY

Modulation of Post-Antibiotic Bacterial Community Reassembly and Host Response by Candida albicans

(2013) John R. Erb Downward et al.   Scientific Reports

Dectin-1 Is Essential for Reverse Transcytosis of Glycosylated SIgA-Antigen Complexes by Intestinal M Cells

(2013) Nicolas Rochereau et al.   PLOS BIOLOGY

Bruton's Tyrosine Kinase (BTK) and Vav1 Contribute to Dectin1-Dependent Phagocytosis of Candida albicans in Macrophages

(2013) Karin Strijbis et al.   PLoS Pathogens

Immunomodulation of Fungal β-Glucan in Host Defense Signaling by Dectin-1

(2012) Sainkhuu Batbayar et al.   Biomolecules & Therapeutics

Diversity, stability and resilience of the human gut microbiota

(2012) Catherine A. Lozupone et al.   NATURE

C-type lectin receptors orchestrate antifungal immunity

(2012) Sarah E Hardison et al.   NATURE IMMUNOLOGY

Interactions Between Commensal Fungi and the C-Type Lectin Receptor Dectin-1 Influence Colitis

(2012) I. D. Iliev et al.   SCIENCE

Innate Antifungal Immunity: The Key Role of Phagocytes

(2011) Gordon D. Brown   Annual Review of Immunology

Crohn disease–associated adherent-invasive E. coli bacteria target mouse and human Peyer’s patches via long polar fimbriae

(2011) Benoit Chassaing et al.   JOURNAL OF CLINICAL INVESTIGATION

Activation of the innate immune receptor Dectin-1 upon formation of a ‘phagocytic synapse’

(2011) Helen S. Goodridge et al.   NATURE

Candida albicans Yeast and Hyphae are Discriminated by MAPK Signaling in Vaginal Epithelial Cells

(2011) David L. Moyes et al.   PLoS One

Inflammatory Bowel Disease

(2010) Arthur Kaser et al.   Annual Review of Immunology

Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle

(2009) Eri Ishikawa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

C-type lectin Mincle is an activating receptor for pathogenic fungus,Malassezia

(2009) Sho Yamasaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histoplasma capsulatum at the host–pathogen interface

(2008) Joshua D. Nosanchuk et al.   MICROBES AND INFECTION