Dectin-1 Controls TLR9 Trafficking to Phagosomes Containing β-1,3 Glucan

Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus

(2015) S. Herbst et al.   EMBO Molecular Medicine

The RIG-I-like helicase receptor MDA5 (IFIH1) is involved in the host defense against Candida infections

(2015) M. Jaeger et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

The emerging role of human PYHIN proteins in innate immunity: Implications for health and disease

(2014) Dympna J. Connolly et al.   BIOCHEMICAL PHARMACOLOGY

A Promiscuous Lipid-Binding Protein Diversifies the Subcellular Sites of Toll-like Receptor Signal Transduction

(2014) Kevin S. Bonham et al.   CELL

Differential Use of CARD9 by Dectin-1 in Macrophages and Dendritic Cells

(2014) H. S. Goodridge et al.   JOURNAL OF IMMUNOLOGY

Dectin-1–Dependent LC3 Recruitment to Phagosomes Enhances Fungicidal Activity in Macrophages

(2014) Jenny M. Tam et al.   JOURNAL OF INFECTIOUS DISEASES

Fungal Chitin Dampens Inflammation through IL-10 Induction Mediated by NOD2 and TLR9 Activation

(2014) Jeanette Wagener et al.   PLoS Pathogens

Dectin-1 Activation Controls Maturation of β-1,3-Glucan-containing Phagosomes

(2013) Michael K. Mansour et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The RodA Hydrophobin on Aspergillus fumigatus Spores Masks Dectin-1- and Dectin-2-Dependent Responses and Enhances Fungal Survival In Vivo

(2013) S. d. J. Carrion et al.   JOURNAL OF IMMUNOLOGY

TLR9 Activation Dampens the Early Inflammatory Response to Paracoccidioides brasiliensis, Impacting Host Survival

(2013) João Filipe Menino et al.   PLoS Neglected Tropical Diseases

Aspergillus Galactosaminogalactan Mediates Adherence to Host Constituents and Conceals Hyphal β-Glucan from the Immune System

(2013) Fabrice N. Gravelat et al.   PLoS Pathogens

UNC93B1 mediates differential trafficking of endosomal TLRs

(2013) Bettina L Lee et al.   eLife

Noncanonical Autophagy Is Required for Type I Interferon Secretion in Response to DNA-Immune Complexes

(2012) Jill Henault et al.   IMMUNITY

Lymphotoxin   Receptor Activation on Macrophages Induces Cross-Tolerance to TLR4 and TLR9 Ligands

(2012) N. Wimmer et al.   JOURNAL OF IMMUNOLOGY

Cell-Specific TLR9 Trafficking in Primary APCs of Transgenic TLR9-GFP Mice

(2012) A. M. Avalos et al.   JOURNAL OF IMMUNOLOGY

Dectin-1 Stimulation Induces Suppressor of Cytokine Signaling 1, Thereby Modulating TLR Signaling and T Cell Responses

(2012) M. E. Eberle et al.   JOURNAL OF IMMUNOLOGY

Relative Contributions of Dectin-1 and Complement to Immune Responses to Particulate  -Glucans

(2012) H. Huang et al.   JOURNAL OF IMMUNOLOGY

Type I Interferons Promote Fatal Immunopathology by Regulating Inflammatory Monocytes and Neutrophils during Candida Infections

(2012) Olivia Majer et al.   PLoS Pathogens

Infectious Diseases in Patients with IRAK-4, MyD88, NEMO, or I B  Deficiency

(2011) C. Picard et al.   CLINICAL MICROBIOLOGY REVIEWS

Recognition of yeast nucleic acids triggers a host-protective type I interferon response

(2011) Carmelo Biondo et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Granulin Is a Soluble Cofactor for Toll-like Receptor 9 Signaling

(2011) Boyoun Park et al.   IMMUNITY

Toll-Like Receptor 9 Modulates Macrophage Antifungal Effector Function during Innate Recognition of Candida albicans and Saccharomyces cerevisiae

(2011) Pia V. Kasperkovitz et al.   INFECTION AND IMMUNITY

Toll-Like Receptor 9-Dependent Activation of Bone Marrow-Derived Dendritic Cells byURA5DNA from Cryptococcus neoformans

(2011) Misuzu Tanaka et al.   INFECTION AND IMMUNITY

Use of fungal derived polysaccharide-conjugated particles to probe Dectin-1 responses in innate immunity

(2011) Jenny M. Tam et al.   Integrative Biology

Interferons in Autoimmune and Inflammatory Diseases: Regulation and Roles

(2011) Divaker Choubey et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Emerging opportunistic yeast infections

(2011) Marisa H Miceli et al.   LANCET INFECTIOUS DISEASES

Immunogenicity of Whole-Parasite Vaccines against Plasmodium falciparum Involves Malarial Hemozoin and Host TLR9

(2010) Cevayir Coban et al.   Cell Host & Microbe

Syk-coupled C-type lectin receptors that mediate cellular activation via single tyrosine based activation motifs

(2010) Ann M. Kerrigan et al.   IMMUNOLOGICAL REVIEWS

Tripartite-Motif Protein 30 Negatively Regulates NLRP3 Inflammasome Activation by Modulating Reactive Oxygen Species Production

(2010) Y. Hu et al.   JOURNAL OF IMMUNOLOGY

TLR9 Is Actively Recruited to Aspergillus fumigatus Phagosomes and Requires the N-Terminal Proteolytic Cleavage Domain for Proper Intracellular Trafficking

(2010) P. V. Kasperkovitz et al.   JOURNAL OF IMMUNOLOGY

Interferon-Inducible p200-Family Proteins as Novel Sensors of Cytoplasmic DNA: Role in Inflammation and Autoimmunity

(2010) Divaker Choubey et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Bifurcation of Toll-Like Receptor 9 Signaling by Adaptor Protein 3

(2010) M. Sasai et al.   SCIENCE

Distinct Roles for Dectin-1 and TLR4 in the Pathogenesis of Aspergillus fumigatus Keratitis

(2010) Sixto M. Leal et al.   PLoS Pathogens

Requisite Role for the Dectin-1  -Glucan Receptor in Pulmonary Defense against Aspergillus fumigatus

(2009) J. L. Werner et al.   JOURNAL OF IMMUNOLOGY

Immune Sensing of Aspergillus fumigatus Proteins, Glycolipids, and Polysaccharides and the Impact on Th Immunity and Vaccination

(2009) S. Bozza et al.   JOURNAL OF IMMUNOLOGY

Surface hydrophobin prevents immune recognition of airborne fungal spores

(2009) Vishukumar Aimanianda et al.   NATURE

Human Dectin-1 Deficiency and Mucocutaneous Fungal Infections

(2009) Bart Ferwerda et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dectin-1 synergizes with TLR2 and TLR4 for cytokine production in human primary monocytes and macrophages

(2008) Gerben Ferwerda et al.   CELLULAR MICROBIOLOGY

Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors

(2008) Kevin M. Dennehy et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Toll-Like Receptor 9-Dependent Immune Activation by Unmethylated CpG Motifs in Aspergillus fumigatus DNA

(2008) Z. G. Ramirez-Ortiz et al.   INFECTION AND IMMUNITY

The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor

(2008) Sarah E. Ewald et al.   NATURE

Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9

(2008) Boyoun Park et al.   NATURE IMMUNOLOGY

Stage-Specific Sampling by Pattern Recognition Receptors during Candida albicans Phagocytosis

(2008) Sigrid E. M. Heinsbroek et al.   PLoS Pathogens