Antifungal innate immunity: recognition and inflammatory networks

Pattern recognition pathways leading to a Th2 cytokine bias in allergic bronchopulmonary aspergillosis patients

(2015) K. L. Becker et al.   CLINICAL AND EXPERIMENTAL ALLERGY

In Vitro Effects of Candida albicans and Aspergillus fumigatus on Dendritic Cells and the Role of Beta Glucan in this Effect

(2015) Isil Fidan et al.   Advances in Clinical and Experimental Medicine

Two independent killing mechanisms of Candida albicans by human neutrophils: evidence from innate immunity defects

(2014) R. P. Gazendam et al.   BLOOD

Trained Immunity or Tolerance: Opposing Functional Programs Induced in Human Monocytes after Engagement of Various Pattern Recognition Receptors

(2014) Daniela C. Ifrim et al.   Clinical and Vaccine Immunology

Differential role of NK cells againstCandida albicansinfection in immunocompetent or immunocompromised mice

(2014) Jessica Quintin et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The Macrophage-Inducible C-Type Lectin, Mincle, Is an Essential Component of the Innate Immune Response to Candida albicans

(2014) C. A. Wells et al.   JOURNAL OF IMMUNOLOGY

TH17 Cells Mediate Steroid-Resistant Airway Inflammation and Airway Hyperresponsiveness in Mice

(2014) L. McKinley et al.   JOURNAL OF IMMUNOLOGY

Role of Neutrophils in IL-17-Dependent Immunity to Mucosal Candidiasis

(2014) A. R. Huppler et al.   JOURNAL OF IMMUNOLOGY

IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans

(2014) Antonella de Luca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteomic characterization of human proinflammatory M1 and anti-inflammatory M2 macrophages and their response toCandida albicans

(2014) Jose Antonio Reales-Calderón et al.   PROTEOMICS

Fungal Chitin Dampens Inflammation through IL-10 Induction Mediated by NOD2 and TLR9 Activation

(2014) Jeanette Wagener et al.   PLoS Pathogens

Inflammatory Monocytes Orchestrate Innate Antifungal Immunity in the Lung

(2014) Vanessa Espinosa et al.   PLoS Pathogens

Epidemiology and risk factors for invasive candidiasis

(2014) Nur Yapar   Therapeutics and Clinical Risk Management

IL-33–Responsive Innate Lymphoid Cells Are an Important Source of IL-13 in Chronic Rhinosinusitis with Nasal Polyps

(2013) Joanne L. Shaw et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Antimicrobial activity of pure platelet-rich plasma against microorganisms isolated from oral cavity

(2013) Lorenzo Drago et al.   BMC MICROBIOLOGY

Dectin-2 is predominately macrophage restricted and exhibits conspicuous expression during Aspergillus fumigatus invasion in human lung

(2013) He Sun et al.   CELLULAR IMMUNOLOGY

Azole resistance in Aspergillus fumigatus

(2013) Edith Vermeulen et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Genetic susceptibility toCandidainfections

(2013) Sanne P. Smeekens et al.   EMBO Molecular Medicine

Autophagy is redundant for the host defense against systemic Candida albicans infections

(2013) S. P. Smeekens et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

C-Type Lectin Receptors Dectin-3 and Dectin-2 Form a Heterodimeric Pattern-Recognition Receptor for Host Defense against Fungal Infection

(2013) Le-Le Zhu et al.   IMMUNITY

Interferon-β Production via Dectin-1-Syk-IRF5 Signaling in Dendritic Cells Is Crucial for Immunity to C. albicans

(2013) Carlos del Fresno et al.   IMMUNITY

Role of Dectin-2 for Host Defense against Systemic Infection with Candida glabrata

(2013) Daniela C. Ifrim et al.   INFECTION AND IMMUNITY

Candida albicans Airway Exposure Primes the Lung Innate Immune Response against Pseudomonas aeruginosa Infection through Innate Lymphoid Cell Recruitment and Interleukin-22-Associated Mucosal Response

(2013) Jean Baptiste Mear et al.   INFECTION AND IMMUNITY

CX3CR1-dependent renal macrophage survival promotes Candida control and host survival

(2013) Michail S. Lionakis et al.   JOURNAL OF CLINICAL INVESTIGATION

Corticosteroids Block Autophagy Protein Recruitment in Aspergillus fumigatus Phagosomes via Targeting Dectin-1/Syk Kinase Signaling

(2013) I. Kyrmizi et al.   JOURNAL OF IMMUNOLOGY

Monocyte- and Macrophage-Targeted NADPH Oxidase Mediates Antifungal Host Defense and Regulation of Acute Inflammation in Mice

(2013) M. J. Grimm et al.   JOURNAL OF IMMUNOLOGY

Aspergillus fumigatus-Induced IL-22 Is Not Restricted to a Specific Th Cell Subset and Is Dependent on Complement Receptor 3

(2013) M. S. Gresnigt et al.   JOURNAL OF IMMUNOLOGY

Human Natural Killer Cells Acting as Phagocytes Against Candida albicans and Mounting an Inflammatory Response That Modulates Neutrophil Antifungal Activity

(2013) Jessica Voigt et al.   JOURNAL OF INFECTIOUS DISEASES

Inflammatory Monocytes Mediate Early and Organ-Specific Innate Defense During Systemic Candidiasis

(2013) Lisa Y. Ngo et al.   JOURNAL OF INFECTIOUS DISEASES

Galectin-3 plays an important role in protection against disseminated candidiasis

(2013) Jennifer R. Linden et al.   MEDICAL MYCOLOGY

Activation of neutrophils by autocrine IL-17A–IL-17RC interactions during fungal infection is regulated by IL-6, IL-23, RORγt and dectin-2

(2013) Patricia R Taylor et al.   NATURE IMMUNOLOGY

Invariant natural killer T cells recognize a fungal glycosphingolipid that can induce airway hyperreactivity

(2013) Lee A Albacker et al.   NATURE MEDICINE

Human Genetic Susceptibility to Invasive Aspergillosis

(2013) Cristina Cunha et al.   PLoS Pathogens

Neutrophil Function: From Mechanisms to Disease

(2012) Borko Amulic et al.   Annual Review of Immunology

Candida albicans Infection Affords Protection against Reinfection via Functional Reprogramming of Monocytes

(2012) Jessica Quintin et al.   Cell Host & Microbe

Macrophage Autophagy in Immunity to Cryptococcus neoformans and Candida albicans

(2012) André Moraes Nicola et al.   INFECTION AND IMMUNITY

Cutting Edge: IL-17-Secreting Innate Lymphoid Cells Are Essential for Host Defense against Fungal Infection

(2012) A. Gladiator et al.   JOURNAL OF IMMUNOLOGY

The  -Glucan Receptor Dectin-1 Promotes Lung Immunopathology during Fungal Allergy via IL-22

(2012) L. M. Lilly et al.   JOURNAL OF IMMUNOLOGY

Aspergillus fumigatus Activates Thrombocytes by Secretion of Soluble Compounds

(2012) Cornelia Speth et al.   JOURNAL OF INFECTIOUS DISEASES

Persistence versus Escape: Aspergillus terreus and Aspergillus fumigatus Employ Different Strategies during Interactions with Macrophages

(2012) Silvia Slesiona et al.   PLoS One

The Acute Neutrophil Response Mediated by S100 Alarmins during Vaginal Candida Infections Is Independent of the Th17-Pathway

(2012) Junko Yano et al.   PLoS One

TLR3 essentially promotes protective class I-restricted memory CD8+ T-cell responses to Aspergillus fumigatus in hematopoietic transplanted patients

(2011) A. Carvalho et al.   BLOOD

Killing by neutrophil extracellular traps: fact or folklore?

(2011) R. Menegazzi et al.   BLOOD

A Nonredundant Role for Plasmacytoid Dendritic Cells in Host Defense against the Human Fungal Pathogen Aspergillus fumigatus

(2011) Zaida G. Ramirez-Ortiz et al.   Cell Host & Microbe

Recognition of yeast nucleic acids triggers a host-protective type I interferon response

(2011) Carmelo Biondo et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Neutrophils Produce Interleukin 17A (IL-17A) in a Dectin-1- and IL-23-Dependent Manner during Invasive Fungal Infection

(2011) Jessica L. Werner et al.   INFECTION AND IMMUNITY

Conventional Dendritic Cells Mount a Type I IFN Response against Candida spp. Requiring Novel Phagosomal TLR7-Mediated IFN-  Signaling

(2011) C. Bourgeois et al.   JOURNAL OF IMMUNOLOGY

Human NK Cells Display Important Antifungal Activity against Aspergillus fumigatus, Which Is Directly Mediated by IFN-  Release

(2011) M. Bouzani et al.   JOURNAL OF IMMUNOLOGY

Activation of the innate immune receptor Dectin-1 upon formation of a ‘phagocytic synapse’

(2011) Helen S. Goodridge et al.   NATURE

STAT1Mutations in Autosomal Dominant Chronic Mucocutaneous Candidiasis

(2011) Frank L. van de Veerdonk et al.   NEW ENGLAND JOURNAL OF MEDICINE

TNF-  from inflammatory dendritic cells (DCs) regulates lung IL-17A/IL-5 levels and neutrophilia versus eosinophilia during persistent fungal infection

(2011) M. Fei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Biphasic Innate Immune MAPK Response Discriminates between the Yeast and Hyphal Forms of Candida albicans in Epithelial Cells

(2010) David L. Moyes et al.   Cell Host & Microbe

Dectin-2 Recognition of α-Mannans and Induction of Th17 Cell Differentiation Is Essential for Host Defense against Candida albicans

(2010) Shinobu Saijo et al.   IMMUNITY

The L412F variant of Toll-like receptor 3 (TLR3) is associated with cutaneous candidiasis, increased susceptibility to cytomegalovirus, and autoimmunity

(2010) Amit Nahum et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Human Natural Killer Cells Exhibit Direct Activity Against Aspergillus fumigatus Hyphae, But Not Against Resting Conidia

(2010) Stanislaw Schmidt et al.   JOURNAL OF INFECTIOUS DISEASES

NETs formed by human neutrophils inhibit growth of the pathogenic mold Aspergillus fumigatus

(2010) Allison McCormick et al.   MICROBES AND INFECTION

Aspergillus fumigatus Stimulates the NLRP3 Inflammasome through a Pathway Requiring ROS Production and the Syk Tyrosine Kinase

(2010) Najwane Saïd-Sadier et al.   PLoS One

Production of Extracellular Traps against Aspergillus fumigatus In Vitro and in Infected Lung Tissue Is Dependent on Invading Neutrophils and Influenced by Hydrophobin RodA

(2010) Sandra Bruns et al.   PLoS Pathogens

Inflammatory Monocytes Facilitate Adaptive CD4 T Cell Responses during Respiratory Fungal Infection

(2009) Tobias M. Hohl et al.   Cell Host & Microbe

The Macrophage Mannose Receptor Induces IL-17 in Response to Candida albicans

(2009) Frank L. van de Veerdonk et al.   Cell Host & Microbe

An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans

(2009) Amy G. Hise et al.   Cell Host & Microbe

Anti-Aspergillushuman host defence relies on type 1 T helper (Th1), rather than type 17 T helper (Th17), cellular immunity

(2009) Louis Y. A. Chai et al.   IMMUNOLOGY

Activation of Platelets by Aspergillus fumigatus and Potential Role of Platelets in the Immunopathogenesis of Aspergillosis

(2009) E. K. Rodland et al.   INFECTION AND IMMUNITY

Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis

(2009) Heather R. Conti et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection

(2009) Matthew J. Robinson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Early NK Cell-Derived IFN-  Is Essential to Host Defense in Neutropenic Invasive Aspergillosis

(2009) S. J. Park et al.   JOURNAL OF IMMUNOLOGY

Essential Role for Neutrophils but not Alveolar Macrophages at Early Time Points followingAspergillus fumigatusInfection

(2009) Monica M. Mircescu et al.   JOURNAL OF INFECTIOUS DISEASES

Intranasally delivered siRNA targeting PI3K/Akt/mTOR inflammatory pathways protects from aspergillosis

(2009) P Bonifazi et al.   Mucosal Immunology

Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence

(2009) Olaf Gross et al.   NATURE

Neutrophil Extracellular Traps Contain Calprotectin, a Cytosolic Protein Complex Involved in Host Defense against Candida albicans

(2009) Constantin F. Urban et al.   PLoS Pathogens

Phagocytosis of Aspergillus fumigatus conidia by primary nasal epithelial cells in vitro

(2008) Françoise Botterel et al.   BMC MICROBIOLOGY

Dendritic Cell Interaction withCandida albicansCritically Depends onN-Linked Mannan

(2008) Alessandra Cambi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Toll-like Receptor 4 Polymorphisms and Aspergillosis in Stem-Cell Transplantation

(2008) Pierre-Yves Bochud et al.   NEW ENGLAND JOURNAL OF MEDICINE

An integrated model of the recognition of Candida albicans by the innate immune system

(2007) Mihai G. Netea et al.   NATURE REVIEWS MICROBIOLOGY