The role of pattern recognition receptors in the innate recognition ofCandida albicans

In Vitro Effects of Candida albicans and Aspergillus fumigatus on Dendritic Cells and the Role of Beta Glucan in this Effect

(2015) Isil Fidan et al.   Advances in Clinical and Experimental Medicine

Interplay between Candida albicans and the Antimicrobial Peptide Armory

(2014) Marc Swidergall et al.   EUKARYOTIC CELL

Masking of β(1-3)-Glucan in the Cell Wall of Candida albicans from Detection by Innate Immune Cells Depends on Phosphatidylserine

(2014) Sarah E. Davis et al.   INFECTION AND IMMUNITY

CD44 Suppresses TLR-Mediated Inflammation

(2014) H. Kawana et al.   JOURNAL OF IMMUNOLOGY

Mannose-Binding Lectin (MBL) Facilitates Opsonophagocytosis of Yeasts but Not of Bacteria despite MBL Binding

(2014) N. Brouwer et al.   JOURNAL OF IMMUNOLOGY

The Macrophage-Inducible C-Type Lectin, Mincle, Is an Essential Component of the Innate Immune Response to Candida albicans

(2014) C. A. Wells et al.   JOURNAL OF IMMUNOLOGY

Dectin-2 Recognition of House Dust Mite Triggers Cysteinyl Leukotriene Generation by Dendritic Cells

(2014) N. A. Barrett et al.   JOURNAL OF IMMUNOLOGY

Discovery of a “White-Gray-Opaque” Tristable Phenotypic Switching System in Candida albicans: Roles of Non-genetic Diversity in Host Adaptation

(2014) Li Tao et al.   PLOS BIOLOGY

Syk Signaling in Dendritic Cells Orchestrates Innate Resistance to Systemic Fungal Infection

(2014) Paul G. Whitney et al.   PLoS Pathogens

Fungal Chitin Dampens Inflammation through IL-10 Induction Mediated by NOD2 and TLR9 Activation

(2014) Jeanette Wagener et al.   PLoS Pathogens

Gene polymorphisms in pattern recognition receptors and susceptibility to idiopathic recurrent vulvovaginal candidiasis

(2014) Diana C. Rosentul et al.   Frontiers in Microbiology

Epidemiology and risk factors for invasive candidiasis

(2014) Nur Yapar   Therapeutics and Clinical Risk Management

Galectin-3 Modulates Th17 Responses by Regulating Dendritic Cell Cytokines

(2013) Agnes Fermin Lee et al.   AMERICAN JOURNAL OF PATHOLOGY

Invasive fungal infection and impaired neutrophil killing in human CARD9 deficiency

(2013) A. Drewniak et al.   BLOOD

Candida albicans Triggers NLRP3-Mediated Pyroptosis in Macrophages

(2013) Melanie Wellington et al.   EUKARYOTIC CELL

C-Type Lectin Receptors Dectin-3 and Dectin-2 Form a Heterodimeric Pattern-Recognition Receptor for Host Defense against Fungal Infection

(2013) Le-Le Zhu et al.   IMMUNITY

Interferon-β Production via Dectin-1-Syk-IRF5 Signaling in Dendritic Cells Is Crucial for Immunity to C. albicans

(2013) Carlos del Fresno et al.   IMMUNITY

Lactobacillus crispatus modulates epithelial cell defense against Candida albicans through Toll-like receptors 2 and 4, interleukin 8 and human β-defensins 2 and 3

(2013) Antonietta Rizzo et al.   IMMUNOLOGY LETTERS

Vaginal Epithelial Cell-Derived S100 Alarmins Induced by Candida albicans via Pattern Recognition Receptor Interactions Are Sufficient but Not Necessary for the Acute Neutrophil Response during Experimental Vaginal Candidiasis

(2013) Junko Yano et al.   INFECTION AND IMMUNITY

Dectin-1 Activation Controls Maturation of β-1,3-Glucan-containing Phagosomes

(2013) Michael K. Mansour et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel Structural Features inCandida albicansHyphal Glucan Provide a Basis for Differential Innate Immune Recognition of HyphaeVersusYeast

(2013) Douglas W. Lowman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Galectin-3 plays an important role in protection against disseminated candidiasis

(2013) Jennifer R. Linden et al.   MEDICAL MYCOLOGY

A developmental program for Candida commensalism

(2013) Neil A R Gow   NATURE GENETICS

Deficient Beta-Mannosylation of Candida albicans Phospholipomannan Affects the Proinflammatory Response in Macrophages

(2013) Audrey Devillers et al.   PLoS One

Candida albicanspathogenicity mechanisms

(2013) François L. Mayer et al.   Virulence

Interactions ofCandida albicanswith host epithelial surfaces

(2013) David W. Williams et al.   Journal of Oral Microbiology

Decisions About Dendritic Cells: Past, Present, and Future

(2012) Ralph M. Steinman   Annual Review of Immunology

Signaling by Myeloid C-Type Lectin Receptors in Immunity and Homeostasis

(2012) David Sancho et al.   Annual Review of Immunology

The role of galectin-3 in phagocytosis ofCandida albicansandCandida parapsilosisby human neutrophils

(2012) Jennifer R. Linden et al.   CELLULAR MICROBIOLOGY

Importance of the Candida albicans cell wall during commensalism and infection

(2012) Neil AR Gow et al.   CURRENT OPINION IN MICROBIOLOGY

Recognition of fungal RNA by TLR7 has a nonredundant role in host defense against experimental candidiasis

(2012) Carmelo Biondo et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Secreted aspartic proteases ofCandida albicansactivate the NLRP3 inflammasome

(2012) Donatella Pietrella et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Syk Kinase-Coupled C-type Lectin Receptors Engage Protein Kinase C-δ to Elicit Card9 Adaptor-Mediated Innate Immunity

(2012) Dominikus Strasser et al.   IMMUNITY

Fungi Subvert Vaccine T Cell Priming at the Respiratory Mucosa by Preventing Chemokine-Induced Influx of Inflammatory Monocytes

(2012) Marcel Wüthrich et al.   IMMUNITY

Mincle polarizes human monocyte and neutrophil responses to Candida albicans

(2012) Dipti Vijayan et al.   IMMUNOLOGY AND CELL BIOLOGY

Interplay between Candida albicans and the Mammalian Innate Host Defense

(2012) Shih-Chin Cheng et al.   INFECTION AND IMMUNITY

Cutting Edge: Nlrp10 Is Essential for Protective Antifungal Adaptive Immunity against Candida albicans

(2012) S. Joly et al.   JOURNAL OF IMMUNOLOGY

Toll-like Receptor 1 Polymorphisms Increase Susceptibility to Candidemia

(2012) Theo S. Plantinga et al.   JOURNAL OF INFECTIOUS DISEASES

Th17 cells confer long-term adaptive immunity to oral mucosal Candida albicans infections

(2012) N Hernández-Santos et al.   Mucosal Immunology

C-type lectin receptors orchestrate antifungal immunity

(2012) Sarah E Hardison et al.   NATURE IMMUNOLOGY

Sensing and reacting to microbes through the inflammasomes

(2012) Luigi Franchi et al.   NATURE IMMUNOLOGY

Differential Dependencies of Monocytes and Neutrophils on Dectin-1, Dectin-2 and Complement for the Recognition of Fungal Particles in Inflammation

(2012) Jacqueline U. McDonald et al.   PLoS One

Interactions Between Commensal Fungi and the C-Type Lectin Receptor Dectin-1 Influence Colitis

(2012) I. D. Iliev et al.   SCIENCE

The role of dendritic cells in the innate recognition of pathogenic fungi (A. fumigatus,C. neoformansandC. albicans)

(2012) Zaida G. Ramirez-Ortiz et al.   Virulence

Type I Interferons Promote Fatal Immunopathology by Regulating Inflammatory Monocytes and Neutrophils during Candida Infections

(2012) Olivia Majer et al.   PLoS Pathogens

Chemokine Receptor Ccr1 Drives Neutrophil-Mediated Kidney Immunopathology and Mortality in Invasive Candidiasis

(2012) Michail S. Lionakis et al.   PLoS Pathogens

Antifungal Drug Resistance: Mechanisms, Epidemiology, and Consequences for Treatment

(2011) Michael A. Pfaller   AMERICAN JOURNAL OF MEDICINE

Plasmacytoid Dendritic Cells: Recent Progress and Open Questions

(2011) Boris Reizis et al.   Annual Review of Immunology

The biological significance of TLR3 variant, L412F, in conferring susceptibility to cutaneous candidiasis, CMV and autoimmunity

(2011) Amit Nahum et al.   AUTOIMMUNITY REVIEWS

Mucosal Immunity andCandida albicansInfection

(2011) David L. Moyes et al.   Clinical & Developmental Immunology

IL-22 and TNF-α represent a key cytokine combination for epidermal integrity during infection withCandida albicans

(2011) Stefanie Eyerich et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Recognition of yeast nucleic acids triggers a host-protective type I interferon response

(2011) Carmelo Biondo et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis

(2011) Frank L. van de Veerdonk et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Current perspectives on echinocandin class drugs

(2011) David S Perlin   Future Microbiology

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Recognition and Blocking of Innate Immunity Cells by Candida albicans Chitin

(2011) Héctor M. Mora-Montes et al.   INFECTION AND IMMUNITY

Toll-Like Receptor 9 Modulates Macrophage Antifungal Effector Function during Innate Recognition of Candida albicans and Saccharomyces cerevisiae

(2011) Pia V. Kasperkovitz et al.   INFECTION AND IMMUNITY

Gain-of-function humanSTAT1mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis

(2011) Luyan Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Conventional Dendritic Cells Mount a Type I IFN Response against Candida spp. Requiring Novel Phagosomal TLR7-Mediated IFN-  Signaling

(2011) C. Bourgeois et al.   JOURNAL OF IMMUNOLOGY

Candida albicans morphogenesis and host defence: discriminating invasion from colonization

(2011) Neil A. R. Gow et al.   NATURE REVIEWS MICROBIOLOGY

Role of Bcr1-Activated Genes Hwp1 and Hyr1 in Candida Albicans Oral Mucosal Biofilms and Neutrophil Evasion

(2011) Prabhat Dwivedi et al.   PLoS One

From Attachment to Damage: Defined Genes of Candida albicans Mediate Adhesion, Invasion and Damage during Interaction with Oral Epithelial Cells

(2011) Betty Wächtler et al.   PLoS One

Fungal recognition is mediated by the association of dectin-1 and galectin-3 in macrophages

(2011) A. Esteban et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Novel Role for the NLRC4 Inflammasome in Mucosal Defenses against the Fungal Pathogen Candida albicans

(2011) Jeffrey Tomalka et al.   PLoS Pathogens

A Biphasic Innate Immune MAPK Response Discriminates between the Yeast and Hyphal Forms of Candida albicans in Epithelial Cells

(2010) David L. Moyes et al.   Cell Host & Microbe

Epidemiology of Invasive Mycoses in North America

(2010) Michael A. Pfaller et al.   CRITICAL REVIEWS IN MICROBIOLOGY

The role of Syk/CARD9 coupled C-type lectins in antifungal immunity

(2010) Rebecca A. Drummond et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Dectin-2 Recognition of α-Mannans and Induction of Th17 Cell Differentiation Is Essential for Host Defense against Candida albicans

(2010) Shinobu Saijo et al.   IMMUNITY

Epithelial Cell-Derived S100 Calcium-Binding Proteins as Key Mediators in the Hallmark Acute Neutrophil Response during Candida Vaginitis

(2010) J. Yano et al.   INFECTION AND IMMUNITY

Pathways Regulating Cytosolic Phospholipase A2Activation and Eicosanoid Production in Macrophages byCandida albicans

(2010) Saritha Suram et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peroxisome Proliferator-activated Receptor γ Negatively Regulates IFN-β Production in Toll-like Receptor (TLR) 3- and TLR4-stimulated Macrophages by Preventing Interferon Regulatory Factor 3 Binding to the IFN-β Promoter

(2010) Wei Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epithelial Cells and Innate Antifungal Defense

(2010) G. Weindl et al.   JOURNAL OF DENTAL RESEARCH

The expression of β-defensin-2, 3 and LL-37 induced by Candida albicans phospholipomannan in human keratinocytes

(2010) Min Li et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Candida albicans Dampens Host Defense by Downregulating IL-17 Production

(2010) S.-C. Cheng et al.   JOURNAL OF IMMUNOLOGY

IL-23 and IL-17A, but Not IL-12 and IL-22, Are Required for Optimal Skin Host Defense against Candida albicans

(2010) S. Kagami et al.   JOURNAL OF IMMUNOLOGY

Organ-Specific Innate Immune Responses in a Mouse Model of Invasive Candidiasis

(2010) Michail S. Lionakis et al.   Journal of Innate Immunity

Pattern Recognition via the Toll-Like Receptor System in the Human Female Genital Tract

(2010) Kaei Nasu et al.   MEDIATORS OF INFLAMMATION

Absence of TLR2 influences survival of neutrophils after infection withCandida albicans

(2010) Venessa Tessarolli et al.   MEDICAL MYCOLOGY

Epithelial crosstalk at the microbiota-mucosal interface

(2010) J. M. Wells et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Current Views of Toll-Like Receptor Signaling Pathways

(2010) Masahiro Yamamoto et al.   Gastroenterology Research and Practice

Characterization of the Oral Fungal Microbiome (Mycobiome) in Healthy Individuals

(2010) Mahmoud A. Ghannoum et al.   PLoS Pathogens

A Novel Pseudopodial Component of the Dendritic Cell Anti-Fungal Response: The Fungipod

(2010) Aaron K. Neumann et al.   PLoS Pathogens

Host Cell Invasion and Virulence Mediated by Candida albicans Ssa1

(2010) Jianing N. Sun et al.   PLoS Pathogens

Inflammatory Monocytes Facilitate Adaptive CD4 T Cell Responses during Respiratory Fungal Infection

(2009) Tobias M. Hohl et al.   Cell Host & Microbe

Th17 Cells Bounce off the Fungal Wall

(2009) Stuart M. Levitz   Cell Host & Microbe

The Macrophage Mannose Receptor Induces IL-17 in Response to Candida albicans

(2009) Frank L. van de Veerdonk et al.   Cell Host & Microbe

An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans

(2009) Amy G. Hise et al.   Cell Host & Microbe

Candida albicansinternalization by host cells is mediated by a clathrin-dependent mechanism

(2009) Emilia Moreno-Ruiz et al.   CELLULAR MICROBIOLOGY

Leukocyte Dectin-1 expression is differentially regulated in fungal versus polymicrobial sepsis

(2009) Tammy R. Ozment-Skelton et al.   CRITICAL CARE MEDICINE

Toll-Like Receptor 9-Dependent Activation of Myeloid Dendritic Cells by Deoxynucleic Acids from Candida albicans

(2009) A. Miyazato et al.   INFECTION AND IMMUNITY

Activation of Toll-like receptors 2 and 4 in Aspergillus fumigatus keratitis

(2009) Jie Zhao et al.   Innate Immunity

Evolutionarily conserved recognition and innate immunity to fungal pathogens by the scavenger receptors SCARF1 and CD36

(2009) Terry K. Means et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis

(2009) Heather R. Conti et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection

(2009) Matthew J. Robinson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Involvement of the NLRP3 Inflammasome in Innate and Humoral Adaptive Immune Responses to Fungal  -Glucan

(2009) H. Kumar et al.   JOURNAL OF IMMUNOLOGY

Bacterial DNA Activates Endothelial Cells and Promotes Neutrophil Adherence through TLR9 Signaling

(2009) D. El Kebir et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Candida albicans Hyphae Formation Triggers Activation of the Nlrp3 Inflammasome

(2009) S. Joly et al.   JOURNAL OF IMMUNOLOGY

Complement receptor 3, not Dectin-1, is the major receptor on human neutrophils for β-glucan-bearing particles

(2009) Robin van Bruggen et al.   MOLECULAR IMMUNOLOGY

Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence

(2009) Olaf Gross et al.   NATURE

Dectin-1 directs T helper cell differentiation by controlling noncanonical NF-κB activation through Raf-1 and Syk

(2009) Sonja I Gringhuis et al.   NATURE IMMUNOLOGY

Human Dectin-1 Deficiency and Mucocutaneous Fungal Infections

(2009) Bart Ferwerda et al.   NEW ENGLAND JOURNAL OF MEDICINE

A HomozygousCARD9Mutation in a Family with Susceptibility to Fungal Infections

(2009) Erik-Oliver Glocker et al.   NEW ENGLAND JOURNAL OF MEDICINE

C-type lectin Mincle is an activating receptor for pathogenic fungus,Malassezia

(2009) Sho Yamasaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NLR-mediated control of inflammasome assembly in the host response against bacterial pathogens

(2009) Igor E. Brodsky et al.   SEMINARS IN IMMUNOLOGY

ORIGINAL ARTICLE: Quantification and Comparison of Toll-Like Receptor Expression and Responsiveness in Primary and Immortalized Human Female Lower Genital Tract Epithelia

(2008) Melissa M. Herbst-Kralovetz et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors

(2008) Kevin M. Dennehy et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Generating cell surface diversity inCandida albicansand other fungal pathogens

(2008) Kerstin Nather et al.   FEMS MICROBIOLOGY LETTERS

Candida albicans-Endothelial Cell Interactions: a Key Step in the Pathogenesis of Systemic Candidiasis

(2008) S. E. W. Grubb et al.   INFECTION AND IMMUNITY

Dendritic Cell Interaction withCandida albicansCritically Depends onN-Linked Mannan

(2008) Alessandra Cambi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential regulation of interleukin 12 and interleukin 23 production in human dendritic cells

(2008) Franca Gerosa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mincle is an ITAM-coupled activating receptor that senses damaged cells

(2008) Sho Yamasaki et al.   NATURE IMMUNOLOGY

The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt

(2008) Nicolas Manel et al.   NATURE IMMUNOLOGY

Microbial Patterns Signaling via Toll-Like Receptors 2 and 5 Contribute to Epithelial Repair, Growth and Survival

(2008) Renat Shaykhiev et al.   PLoS One

Pyogenic Bacterial Infections in Humans with MyD88 Deficiency

(2008) H. von Bernuth et al.   SCIENCE

Role of TLR1 and TLR6 in the host defense against disseminated candidiasis

(2007) Mihai G. Netea et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Antiviral responses of human Fallopian tube epithelial cells to toll-like receptor 3 agonist poly(I:C)

(2007) Mimi Ghosh et al.   FERTILITY AND STERILITY

An integrated model of the recognition of Candida albicans by the innate immune system

(2007) Mihai G. Netea et al.   NATURE REVIEWS MICROBIOLOGY