Innate Antifungal Immunity: The Key Role of Phagocytes

The Induction of Inflammation by Dectin-1 In Vivo Is Dependent on Myeloid Cell Programming and the Progression of Phagocytosis

(2014) M. Rosas et al.   JOURNAL OF IMMUNOLOGY

CCR2 Mediates Conventional Dendritic Cell Recruitment and the Formation of Bronchovascular Mononuclear Cell Infiltrates in the Lungs of Mice Infected with Cryptococcus neoformans

(2014) J. J. Osterholzer et al.   JOURNAL OF IMMUNOLOGY

The Macrophage-Inducible C-Type Lectin, Mincle, Is an Essential Component of the Innate Immune Response to Candida albicans

(2014) C. A. Wells et al.   JOURNAL OF IMMUNOLOGY

Differential Use of CARD9 by Dectin-1 in Macrophages and Dendritic Cells

(2014) H. S. Goodridge et al.   JOURNAL OF IMMUNOLOGY

Dectin-2 Recognition of House Dust Mite Triggers Cysteinyl Leukotriene Generation by Dendritic Cells

(2014) N. A. Barrett et al.   JOURNAL OF IMMUNOLOGY

Cryptococcal Interactions with the Host Immune System

(2010) Kerstin Voelz et al.   EUKARYOTIC CELL

Dectin-2 Recognition of α-Mannans and Induction of Th17 Cell Differentiation Is Essential for Host Defense against Candida albicans

(2010) Shinobu Saijo et al.   IMMUNITY

ITAM Receptor Signaling and the NLRP3 Inflammasome in Antifungal Immunity

(2010) Hendrik Poeck et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Calcineurin regulates innate antifungal immunity in neutrophils

(2010) Matthew B. Greenblatt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Variable recognition ofCandida albicansstrains by TLR4 and lectin recognition receptors

(2010) Mihai G. Netea et al.   MEDICAL MYCOLOGY

Host responses to Candida albicans: Th17 cells and mucosal candidiasis

(2010) Heather R. Conti et al.   MICROBES AND INFECTION

Secretion of a fungal protease represents a complement evasion mechanism in cerebral aspergillosis

(2010) Günter Rambach et al.   MOLECULAR IMMUNOLOGY

Aspergillus fumigatus Stimulates the NLRP3 Inflammasome through a Pathway Requiring ROS Production and the Syk Tyrosine Kinase

(2010) Najwane Saïd-Sadier et al.   PLoS One

A Novel Pseudopodial Component of the Dendritic Cell Anti-Fungal Response: The Fungipod

(2010) Aaron K. Neumann et al.   PLoS Pathogens

Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS

(2009) Benjamin J Park et al.   AIDS

Restoration of NET formation by gene therapy in CGD controls aspergillosis

(2009) M. Bianchi et al.   BLOOD

Inflammatory Monocytes Facilitate Adaptive CD4 T Cell Responses during Respiratory Fungal Infection

(2009) Tobias M. Hohl et al.   Cell Host & Microbe

The Macrophage Mannose Receptor Induces IL-17 in Response to Candida albicans

(2009) Frank L. van de Veerdonk et al.   Cell Host & Microbe

Candida albicansactively modulates intracellular membrane trafficking in mouse macrophage phagosomes

(2009) Elena Fernández-Arenas et al.   CELLULAR MICROBIOLOGY

Pattern recognition: recent insights from Dectin-1

(2009) Delyth M Reid et al.   CURRENT OPINION IN IMMUNOLOGY

Fungal metabolism in host niches

(2009) Matthias Brock   CURRENT OPINION IN MICROBIOLOGY

Fungal mechanisms for host iron acquisition

(2009) Daniel Kornitzer   CURRENT OPINION IN MICROBIOLOGY

Nitrosative and oxidative stress responses in fungal pathogenicity

(2009) Alistair JP Brown et al.   CURRENT OPINION IN MICROBIOLOGY

C-type lectins and phagocytosis

(2009) Ann M. Kerrigan et al.   IMMUNOBIOLOGY

Anti-Aspergillushuman host defence relies on type 1 T helper (Th1), rather than type 17 T helper (Th17), cellular immunity

(2009) Louis Y. A. Chai et al.   IMMUNOLOGY

The Glycosylphosphatidylinositol-Anchored Protease Sap9 Modulates the Interaction of Candida albicans with Human Neutrophils

(2009) A. Hornbach et al.   INFECTION AND IMMUNITY

Elucidating the Pathogenesis of Spores from the Human Fungal Pathogen Cryptococcus neoformans

(2009) S. S. Giles et al.   INFECTION AND IMMUNITY

Genetic variability of innate immunity impacts human susceptibility to fungal diseases

(2009) Agostinho Carvalho et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Phospholipase Cγ2 Is Critical for Dectin-1-mediated Ca2+Flux and Cytokine Production in Dendritic Cells

(2009) Shengli Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evolutionarily conserved recognition and innate immunity to fungal pathogens by the scavenger receptors SCARF1 and CD36

(2009) Terry K. Means et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection

(2009) Matthew J. Robinson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Group V Secretory Phospholipase A2 Modulates Phagosome Maturation and Regulates the Innate Immune Response against Candida albicans

(2009) B. Balestrieri et al.   JOURNAL OF IMMUNOLOGY

Requisite Role for the Dectin-1  -Glucan Receptor in Pulmonary Defense against Aspergillus fumigatus

(2009) J. L. Werner et al.   JOURNAL OF IMMUNOLOGY

The CCL7-CCL2-CCR2 Axis Regulates IL-4 Production in Lungs and Fungal Immunity

(2009) W. A. Szymczak et al.   JOURNAL OF IMMUNOLOGY

Surface hydrophobin prevents immune recognition of airborne fungal spores

(2009) Vishukumar Aimanianda et al.   NATURE

Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori

(2009) Sonja I Gringhuis et al.   NATURE IMMUNOLOGY

Human Dectin-1 Deficiency and Mucocutaneous Fungal Infections

(2009) Bart Ferwerda et al.   NEW ENGLAND JOURNAL OF MEDICINE

A HomozygousCARD9Mutation in a Family with Susceptibility to Fungal Infections

(2009) Erik-Oliver Glocker et al.   NEW ENGLAND JOURNAL OF MEDICINE

C-type lectin Mincle is an activating receptor for pathogenic fungus,Malassezia

(2009) Sho Yamasaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neutrophil Extracellular Traps Contain Calprotectin, a Cytosolic Protein Complex Involved in Host Defense against Candida albicans

(2009) Constantin F. Urban et al.   PLoS Pathogens

Antimicrobial properties of lactoferrin

(2008) H JENSSEN et al.   BIOCHIMIE

Toll-like receptors and fungal infections: the role of TLR2, TLR4 and MyD88 in paracoccidioidomycosis

(2008) Vera L. G. Calich et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Substitution of methionine 63 or 83 in S100A9 and cysteine 42 in S100A8 abrogate the antifungal activities of S100A8/A9: potential role for oxidative regulation

(2008) Herve Y. Sroussi et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Live Candida albicans Suppresses Production of Reactive Oxygen Species in Phagocytes

(2008) M. Wellington et al.   INFECTION AND IMMUNITY

Role of the Mannose Receptor in a Murine Model of Cryptococcus neoformans Infection

(2008) J. M. Dan et al.   INFECTION AND IMMUNITY

Dendritic Cell Interaction withCandida albicansCritically Depends onN-Linked Mannan

(2008) Alessandra Cambi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Actin and Phosphoinositide Recruitment to Fully Formed Candida albicans Phagosomes in Mouse Macrophages

(2008) Sigrid E.M. Heinsbroek et al.   Journal of Innate Immunity

Stage-specific innate immune recognition ofAspergillus fumigatusand modulation by echinocandin drugs

(2008) Tobias M. Hohl   MEDICAL MYCOLOGY

Histoplasma capsulatum at the host–pathogen interface

(2008) Joshua D. Nosanchuk et al.   MICROBES AND INFECTION

Cryptococcus neoformans inhibits nitric oxide synthesis caused by CpG-oligodeoxynucleotide-stimulated macrophages in a fashion independent of capsular polysaccharides

(2008) Gang Xiao et al.   MICROBIOLOGY AND IMMUNOLOGY

Complement and fungal pathogens: an update

(2008) Cornelia Speth et al.   MYCOSES

Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease

(2008) Luigina Romani et al.   NATURE

Lysozyme plays a dual role against the dimorphic fungus Paracoccidioides brasiliensis

(2008) Damaris Lopera et al.   REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SAO PAULO

Pyogenic Bacterial Infections in Humans with MyD88 Deficiency

(2008) H. von Bernuth et al.   SCIENCE

Gene targeting demonstrates that inducible nitric oxide synthase is not essential for resistance to oral candidiasis in mice, or for killing ofCandida albicansby macrophagesin vitro

(2008) C. S. Farah et al.   Oral microbiology and immunology

Dynamic, Morphotype-Specific Candida albicans β-Glucan Exposure during Infection and Drug Treatment

(2008) Robert T. Wheeler et al.   PLoS Pathogens

Stage-Specific Sampling by Pattern Recognition Receptors during Candida albicans Phagocytosis

(2008) Sigrid E. M. Heinsbroek et al.   PLoS Pathogens

Characterisation of the phagocytic uptake of Aspergillus fumigatus conidia by macrophages

(2007) Kathrin Luther et al.   MICROBES AND INFECTION

An integrated model of the recognition of Candida albicans by the innate immune system

(2007) Mihai G. Netea et al.   NATURE REVIEWS MICROBIOLOGY

C-type lectin receptors in antifungal immunity

(2007) Janet A. Willment et al.   TRENDS IN MICROBIOLOGY