Bruton's Tyrosine Kinase (BTK) and Vav1 Contribute to Dectin1-Dependent Phagocytosis of Candida albicans in Macrophages

Dual Functions of Bruton's Tyrosine Kinase and Tec Kinase during Fc  Receptor-Induced Signaling and Phagocytosis

(2014) J. Jongstra-Bilen et al.   JOURNAL OF IMMUNOLOGY

Interplay between Candida albicans and the Mammalian Innate Host Defense

(2012) Shih-Chin Cheng et al.   INFECTION AND IMMUNITY

Molecular Basis for Failure of “Atypical” C1 Domain of Vav1 to Bind Diacylglycerol/Phorbol Ester

(2012) Tamas Geczy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interactions Between Commensal Fungi and the C-Type Lectin Receptor Dectin-1 Influence Colitis

(2012) I. D. Iliev et al.   SCIENCE

Btk is a positive regulator in the TREM-1/DAP12 signaling pathway

(2011) T. Ormsby et al.   BLOOD

The β-Glucan Receptor Dectin-1 Activates the Integrin Mac-1 in Neutrophils via Vav Protein Signaling to Promote Candida albicans Clearance

(2011) Xun Li et al.   Cell Host & Microbe

Phagocytosis

(2011) Roberto J. Botelho et al.   CURRENT BIOLOGY

Use of fungal derived polysaccharide-conjugated particles to probe Dectin-1 responses in innate immunity

(2011) Jenny M. Tam et al.   Integrative Biology

Protein kinase Cδ is a critical component of Dectin-1 signaling in primary human monocytes

(2011) Deena H. Elsori et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Fungal recognition is mediated by the association of dectin-1 and galectin-3 in macrophages

(2011) A. Esteban et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Imaging signal transduction during phagocytosis: phospholipids, surface charge, and electrostatic interactions

(2010) Sergio Grinstein   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Tyrosine kinase Btk regulates E-selectin-mediated integrin activation and neutrophil recruitment by controlling phospholipase C (PLC)  2 and PI3K  pathways

(2010) H. Mueller et al.   BLOOD

Class I and class III phosphoinositide 3-kinases are required for actin polymerization that propels phagosomes

(2010) Michal Bohdanowicz et al.   JOURNAL OF CELL BIOLOGY

The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy

(2010) L. A. Honigberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Candida albicansactively modulates intracellular membrane trafficking in mouse macrophage phagosomes

(2009) Elena Fernández-Arenas et al.   CELLULAR MICROBIOLOGY

Vav1 and PI3K are required for phagocytosis of β-glucan and subsequent superoxide generation by microglia

(2009) Vaibhav B. Shah et al.   MOLECULAR IMMUNOLOGY

Early-Expressed Chemokines Predict Kidney Immunopathology in Experimental Disseminated Candida albicans Infections

(2009) Donna M. MacCallum et al.   PLoS One

Mycobacterium abscessusactivates the macrophage innate immune response via a physical and functional interaction between TLR2 and dectin-1

(2008) Dong-Min Shin et al.   CELLULAR MICROBIOLOGY

Actin and Phosphoinositide Recruitment to Fully Formed Candida albicans Phagosomes in Mouse Macrophages

(2008) Sigrid E.M. Heinsbroek et al.   Journal of Innate Immunity

Lifeact: a versatile marker to visualize F-actin

(2008) Julia Riedl et al.   NATURE METHODS

Structural Basis of Protein Kinase C Isoform Function

(2008) Susan F. Steinberg   PHYSIOLOGICAL REVIEWS

Dynamic, Morphotype-Specific Candida albicans β-Glucan Exposure during Infection and Drug Treatment

(2008) Robert T. Wheeler et al.   PLoS Pathogens