Glial pathology and retinal neurotoxicity in the anterior visual pathway in experimental autoimmune encephalomyelitis

Microglia are not required for prion-induced retinal photoreceptor degeneration

(2019) James F. Striebel et al.   Acta Neuropathologica Communications

The contribution of astrocytes to the neuroinflammatory response in multiple sclerosis and experimental autoimmune encephalomyelitis

(2019) Roberta Brambilla   ACTA NEUROPATHOLOGICA

Myeloid cell plasticity in the evolution of central nervous system autoimmunity

(2018) David A. Giles et al.   ANNALS OF NEUROLOGY

Convergent effects of a functional C3 variant on brain atrophy, demyelination, and cognitive impairment in multiple sclerosis

(2018) Tina Roostaei et al.   Multiple Sclerosis Journal

Microglial control of astrocytes in response to microbial metabolites

(2018) Veit Rothhammer et al.   NATURE

Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease

(2018) Seung Pil Yun et al.   NATURE MEDICINE

Convergent effects of a functional C3 variant on brain atrophy, demyelination, and cognitive impairment in multiple sclerosis

(2018) Tina Roostaei et al.   Multiple Sclerosis Journal

Systemic inhibition of the membrane attack complex impedes neuroinflammation in chronic relapsing experimental autoimmune encephalomyelitis

(2018) Iliana Michailidou et al.   Acta Neuropathologica Communications

Long-term safety evaluation of natalizumab for the treatment of multiple sclerosis

(2017) Marinella Clerico et al.   Expert Opinion On Drug Safety

CNS-targeted autoimmunity leads to increased influenza mortality in mice

(2017) Justin D. Glenn et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Retinal layer segmentation in multiple sclerosis: a systematic review and meta-analysis

(2017) Axel Petzold et al.   LANCET NEUROLOGY

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Cell-specific and region-specific transcriptomics in the multiple sclerosis model: Focus on astrocytes

(2017) Noriko Itoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple sclerosis: experimental models and reality

(2016) Hans Lassmann et al.   ACTA NEUROPATHOLOGICA

Complement C3 on microglial clusters in multiple sclerosis occur in chronic but not acute disease: Implication for disease pathogenesis

(2016) Iliana Michailidou et al.   GLIA

Microglia response in retina and optic nerve in chronic experimental autoimmune encephalomyelitis

(2016) Lioba Horstmann et al.   JOURNAL OF NEUROIMMUNOLOGY

Complement is activated in progressive multiple sclerosis cortical grey matter lesions

(2016) Lewis M. Watkins et al.   Journal of Neuroinflammation

Retinal thickness measured with optical coherence tomography and risk of disability worsening in multiple sclerosis: a cohort study

(2016) Elena H Martinez-Lapiscina et al.   LANCET NEUROLOGY

Complement C1q-C3-associated synaptic changes in multiple sclerosis hippocampus

(2015) Iliana Michailidou et al.   ANNALS OF NEUROLOGY

Optical coherence tomography reflects brain atrophy in multiple sclerosis: A four-year study

(2015) Shiv Saidha et al.   ANNALS OF NEUROLOGY

Complement Component C3 and Butyrylcholinesterase Activity Are Associated with Neurodegeneration and Clinical Disability in Multiple Sclerosis

(2015) Shahin Aeinehband et al.   PLoS One

Alterations of the synapse of the inner retinal layers after chronic intraocular pressure elevation in glaucoma animal model

(2014) Hae-Young Lopilly Park et al.   Molecular Brain

Complement activation in multiple sclerosis plaques: an immunohistochemical analysis

(2014) Gillian Ingram et al.   Acta Neuropathologica Communications

Astrocytes play a key role in EAE pathophysiology by orchestrating in the CNS the inflammatory response of resident and peripheral immune cells and by suppressing remyelination

(2013) Roberta Brambilla et al.   GLIA

Cutting Edge: The NLRP3 Inflammasome Links Complement-Mediated Inflammation and IL-1  Release

(2013) F. Laudisi et al.   JOURNAL OF IMMUNOLOGY

Inflammatory demyelination induces glia alterations and ganglion cell loss in the retina of an experimental autoimmune encephalomyelitis model

(2013) Lioba Horstmann et al.   Journal of Neuroinflammation

Relationships Between Retinal Axonal and Neuronal Measures and Global Central Nervous System Pathology in Multiple Sclerosis

(2013) Shiv Saidha et al.   JAMA Neurology

In vivo assessment of retinal neuronal layers in multiple sclerosis with manual and automated optical coherence tomography segmentation techniques

(2012) Michaela A. Seigo et al.   JOURNAL OF NEUROLOGY

C3-dependent mechanism of microglial priming relevant to multiple sclerosis

(2012) V. Ramaglia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optical coherence tomography segmentation reveals ganglion cell layer pathology after optic neuritis

(2011) Stephanie B. Syc et al.   BRAIN

Primary retinal pathology in multiple sclerosis as detected by optical coherence tomography

(2011) Shiv Saidha et al.   BRAIN

Gp130-Dependent Astrocytic Survival Is Critical for the Control of Autoimmune Central Nervous System Inflammation

(2011) F. Haroon et al.   JOURNAL OF IMMUNOLOGY

Visual dysfunction in multiple sclerosis correlates better with optical coherence tomography derived estimates of macular ganglion cell layer thickness than peripapillary retinal nerve fiber layer thickness

(2011) Shiv Saidha et al.   Multiple Sclerosis Journal

Natural History of Multiple Sclerosis: Long-Term Prognostic Factors

(2011) Christel Renoux   NEUROLOGIC CLINICS

The Impact of Utilizing Different Optical Coherence Tomography Devices for Clinical Purposes and in Multiple Sclerosis Trials

(2011) Christina V. Warner et al.   PLoS One

Optic Neuritis and Retinal Ganglion Cell Loss in a Chronic Murine Model of Multiple Sclerosis

(2011) Thomas A. Quinn et al.   Frontiers in Neurology

Demyelination causes synaptic alterations in hippocampi from multiple sclerosis patients

(2010) Ranjan Dutta et al.   ANNALS OF NEUROLOGY

GFAP-Driven GFP Expression in Activated Mouse Müller Glial Cells Aligning Retinal Blood Vessels Following Intravitreal Injection of AAV2/6 Vectors

(2010) Wendy M. Aartsen et al.   PLoS One

Reactive Astrocytes Form Scar-Like Perivascular Barriers to Leukocytes during Adaptive Immune Inflammation of the CNS

(2009) R. R. Voskuhl et al.   JOURNAL OF NEUROSCIENCE

Inflammatory demyelination induces axonal injury and retinal ganglion cell apoptosis in experimental optic neuritis

(2008) Kenneth S. Shindler et al.   EXPERIMENTAL EYE RESEARCH

Behavioral and pathological outcomes in MOG 35–55 experimental autoimmune encephalomyelitis

(2008) M.V. Jones et al.   JOURNAL OF NEUROIMMUNOLOGY