Complement Component C3 and Butyrylcholinesterase Activity Are Associated with Neurodegeneration and Clinical Disability in Multiple Sclerosis

Fibrillar β-amyloid 1-42 alters cytokine secretion, cholinergic signalling and neuronal differentiation

(2014) Linn Malmsten et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Nicotinic Attenuation of Central Nervous System Inflammation and Autoimmunity

(2014) F.-D. Shi et al.   JOURNAL OF IMMUNOLOGY

Initial Assessment of the Pathogenic Mechanisms of the Recently Identified Alzheimer Risk Loci

(2013) Patrick Holton et al.   ANNALS OF HUMAN GENETICS

The Microglial α7-Acetylcholine Nicotinic Receptor Is a Key Element in Promoting Neuroprotection by Inducing Heme Oxygenase-1 via Nuclear Factor Erythroid-2-Related Factor 2

(2013) Esther Parada et al.   ANTIOXIDANTS & REDOX SIGNALING

Oxygen Toxicity Is Reduced by Acetylcholinesterase Inhibition in the Developing Rat Brain

(2013) Marco Sifringer et al.   DEVELOPMENTAL NEUROSCIENCE

Unbiased Expression Mapping Identifies a Link between the Complement and Cholinergic Systems in the Rat Central Nervous System

(2013) R. P. F. Lindblom et al.   JOURNAL OF IMMUNOLOGY

Immunosuppressive therapy reduces axonal damage in progressive multiple sclerosis

(2013) Markus Axelsson et al.   Multiple Sclerosis Journal

A comparative study of CSF neurofilament light and heavy chain protein in MS

(2013) Jens Kuhle et al.   Multiple Sclerosis Journal

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

(2013) Ashley H Beecham et al.   NATURE GENETICS

Functional variability in butyrylcholinesterase activity regulates intrathecal cytokine and astroglial biomarker profiles in patients with Alzheimer's disease

(2013) Taher Darreh-Shori et al.   NEUROBIOLOGY OF AGING

Intense Inflammation and Nerve Damage in Early Multiple Sclerosis Subsides at Older Age: A Reflection by Cerebrospinal Fluid Biomarkers

(2013) Mohsen Khademi et al.   PLoS One

Regulated Extracellular Choline Acetyltransferase Activity— The Plausible Missing Link of the Distant Action of Acetylcholine in the Cholinergic Anti-Inflammatory Pathway

(2013) Swetha Vijayaraghavan et al.   PLoS One

Systemic complement profiling in multiple sclerosis as a biomarker of disease state

(2012) G Ingram et al.   Multiple Sclerosis Journal

Progressive multiple sclerosis: pathology and pathogenesis

(2012) Hans Lassmann et al.   Nature Reviews Neurology

Biological markers in cerebrospinal fluid for axonal impairment in multiple sclerosis: acetylcholinesterase activity cannot be considered a useful biomarker

(2012) T. Antonelli et al.   NEUROLOGICAL SCIENCES

C3-dependent mechanism of microglial priming relevant to multiple sclerosis

(2012) V. Ramaglia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cholinergic imbalance in the multiple sclerosis hippocampus

(2011) Evert-Jan Kooi et al.   ACTA NEUROPATHOLOGICA

Complement 3 and Factor H in Human Cerebrospinal Fluid in Parkinson's Disease, Alzheimer's Disease, and Multiple-System Atrophy

(2011) Yu Wang et al.   AMERICAN JOURNAL OF PATHOLOGY

Complement regulator factor H in multiple sclerosis

(2011) Gillian Ingram et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Differential expression of complement proteins in cerebrospinal fluid from active multiple sclerosis patients

(2011) Yun Li et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Identification of biomarkers for diagnosis and progression of MS by MALDI-TOF mass spectrometry

(2011) CE Teunissen et al.   Multiple Sclerosis Journal

The Expression of VEGF-A Is Down Regulated in Peripheral Blood Mononuclear Cells of Patients with Secondary Progressive Multiple Sclerosis

(2011) Ellen Iacobaeus et al.   PLoS One

Acetylcholine-Synthesizing T Cells Relay Neural Signals in a Vagus Nerve Circuit

(2011) M. Rosas-Ballina et al.   SCIENCE

α7 Nicotinic Acetylcholine Receptor Agonism Confers Neuroprotection Through GSK-3β Inhibition in a Mouse Model of Intracerebral Hemorrhage

(2011) Paul R. Krafft et al.   STROKE

Axonal damage in relapsing multiple sclerosis is markedly reduced by natalizumab

(2010) Martin Gunnarsson et al.   ANNALS OF NEUROLOGY

Evidence for a two-stage disability progression in multiple sclerosis

(2010) E. Leray et al.   BRAIN

Complement regulator factor H as a serum biomarker of multiple sclerosis disease state

(2010) Gillian Ingram et al.   BRAIN

Butyrylcholinesterase activity in multiple sclerosis neuropathology

(2010) Sultan Darvesh et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Systemic infection and delirium: when cytokines and acetylcholine collide

(2010) Willem A van Gool et al.   LANCET

Clinico-pathological evidence that axonal loss underlies disability in progressive multiple sclerosis

(2010) Emma C Tallantyre et al.   Multiple Sclerosis Journal

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

The relation between inflammation and neurodegeneration in multiple sclerosis brains

(2009) Josa M. Frischer et al.   BRAIN

Treatment with a C5aR Antagonist Decreases Pathology and Enhances Behavioral Performance in Murine Models of Alzheimer's Disease

(2009) M. I. Fonseca et al.   JOURNAL OF IMMUNOLOGY

Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice

(2009) I. M. Chiu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complement activation and inhibition: a delicate balance

(2009) A.P. Sjöberg et al.   TRENDS IN IMMUNOLOGY

Complement in multiple sclerosis: its role in disease and potential as a biomarker

(2008) G. Ingram et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

A shift from adaptive to innate immunity: a potential mechanism of disease progression in multiple sclerosis

(2008) Howard L. Weiner   JOURNAL OF NEUROLOGY

Multiple sclerosis

(2008) Alastair Compston et al.   LANCET

Multiple sclerosis-related proteins identified in cerebrospinal fluid by advanced mass spectrometry

(2008) Marcel P. Stoop et al.   PROTEOMICS

Inhibition of acetylcholinesterase in CSF versus brain assessed by 11C-PMP PET in AD patients treated with galantamine

(2006) T. Darreh-Shori et al.   NEUROBIOLOGY OF AGING