The plasma membrane as a mechanochemical transducer

The Role of Membrane Curvature in Nanoscale Topography-Induced Intracellular Signaling

(2018) Hsin-Ya Lou et al.   ACCOUNTS OF CHEMICAL RESEARCH

A curvature-dependent membrane binding by tyrosine kinase Fer involves an intrinsically disordered region

(2018) Hikaru Yamamoto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hypotonic Challenge of Endothelial Cells Increases Membrane Stiffness with No Effect on Tether Force

(2018) Manuela Aseye Ayele Ayee et al.   BIOPHYSICAL JOURNAL

Controlling Cellular Volume via Mechanical and Physical Properties of Substrate

(2018) Kenan Xie et al.   BIOPHYSICAL JOURNAL

Mechanical Transduction and the Dark Energy of Biology

(2018) Frederick Sachs   BIOPHYSICAL JOURNAL

The 2018 biomembrane curvature and remodeling roadmap

(2018) Patricia Bassereau et al.   JOURNAL OF PHYSICS D-APPLIED PHYSICS

The contributions of the actin machinery to endocytic membrane bending and vesicle formation

(2018) Andrea Picco et al.   MOLECULAR BIOLOGY OF THE CELL

Cell-geometry-dependent changes in plasma membrane order direct stem cell signalling and fate

(2018) Thomas C. von Erlach et al.   NATURE MATERIALS

In pursuit of the mechanics that shape cell surfaces

(2018) Alba Diz-Muñoz et al.   Nature Physics

Mechanisms of clathrin-mediated endocytosis

(2018) Marko Kaksonen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Joining forces: crosstalk between biochemical signalling and physical forces orchestrates cellular polarity and dynamics

(2018) Suvrajit Saha et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Reciprocal link between cell biomechanics and exocytosis

(2018) Guan Wang et al.   TRAFFIC

Small GTPases and BAR domain proteins regulate branched actin polymerisation for clathrin and dynamin-independent endocytosis

(2018) Mugdha Sathe et al.   Nature Communications

An Amphipathic Helix Directs Cellular Membrane Curvature Sensing and Function of the BAR Domain Protein PICK1

(2018) Rasmus Herlo et al.   Cell Reports

Portraits of a pressure sensor

(2018) Alexander T Chesler et al.   eLife

Decrease in plasma membrane tension triggers PtdIns(4,5)P2 phase separation to inactivate TORC2

(2018) Margot Riggi et al.   NATURE CELL BIOLOGY

A fluorescent membrane tension probe

(2018) Adai Colom et al.   Nature Chemistry

Cell Membranes Resist Flow

(2018) Zheng Shi et al.   CELL

EHD2 is a mechanotransducer connecting caveolae dynamics with gene transcription

(2018) Stéphanie Torrino et al.   JOURNAL OF CELL BIOLOGY

Mechanochemical feedback control of dynamin independent endocytosis modulates membrane tension in adherent cells

(2018) Joseph Jose Thottacherry et al.   Nature Communications

ATP-dependent membrane remodeling links EHD1 functions to endocytic recycling

(2018) Raunaq Deo et al.   Nature Communications

Control of actin polymerization via the coincidence of phosphoinositides and high membrane curvature

(2017) Frederic Daste et al.   JOURNAL OF CELL BIOLOGY

Mechanical stretch triggers rapid epithelial cell division through Piezo1

(2017) S. A. Gudipaty et al.   NATURE

Actin cortex architecture regulates cell surface tension

(2017) Priyamvada Chugh et al.   NATURE CELL BIOLOGY

Nanoscale manipulation of membrane curvature for probing endocytosis in live cells

(2017) Wenting Zhao et al.   Nature Nanotechnology

The mystery of membrane organization: composition, regulation and roles of lipid rafts

(2017) Erdinc Sezgin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Membrane tension: A challenging but universal physical parameter in cell biology

(2017) Bruno Pontes et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The Unsolved Problem of How Cells Sense Micron-Scale Curvature

(2017) Kevin S. Cannon et al.   TRENDS IN BIOCHEMICAL SCIENCES

Tissue Force Programs Cell Fate and Tumor Aggression

(2017) Jason J. Northey et al.   Cancer Discovery

Structure-based membrane dome mechanism for Piezo mechanosensitivity

(2017) Yusong R Guo et al.   eLife

Topographical interrogation of the living cell surface reveals its role in rapid cell shape changes during phagocytosis and spreading

(2017) Maha A. Al Jumaa et al.   Scientific Reports

Effects of protein crowding on membrane systems

(2016) Gernot Guigas et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Pharmacological targeting of ion channels for cancer therapy: In vivo evidences

(2016) Luigi Leanza et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Anisotropic Membrane Curvature Sensing by Amphipathic Peptides

(2016) Jordi Gómez-Llobregat et al.   BIOPHYSICAL JOURNAL

A Case for the Nuclear Membrane as a Mechanotransducer

(2016) Balázs Enyedi et al.   Cellular and Molecular Bioengineering

Membrane curvature in cell biology: An integration of molecular mechanisms

(2016) Iris K. Jarsch et al.   JOURNAL OF CELL BIOLOGY

The N-Terminal Amphipathic Helix of Endophilin Does Not Contribute to Its Molecular Curvature Generation Capacity

(2016) Zhiming Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ion Permeation and Mechanotransduction Mechanisms of Mechanosensitive Piezo Channels

(2016) Qiancheng Zhao et al.   NEURON

Ion Channels in Endothelial Responses to Fluid Shear Stress

(2016) Kristin A. Gerhold et al.   PHYSIOLOGY

Curvature–undulation coupling as a basis for curvature sensing and generation in bilayer membranes

(2016) Ryan P. Bradley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How curvature-generating proteins build scaffolds on membrane nanotubes

(2016) Mijo Simunovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension

(2016) Charles D. Cox et al.   Nature Communications

Membrane Tension Acts Through PLD2 and mTORC2 to Limit Actin Network Assembly During Neutrophil Migration

(2016) Alba Diz-Muñoz et al.   PLOS BIOLOGY

The More the Tubular: Dynamic Bundling of Actin Filaments for Membrane Tube Formation

(2016) Julian Weichsel et al.   PLoS Computational Biology

Biodegradable Nanoneedles for Localized Delivery of Nanoparticles in Vivo: Exploring the Biointerface

(2015) Ciro Chiappini et al.   ACS Nano

Vascular endothelial cell membranes differentiate between stretch and shear stress through transitions in their lipid phases

(2015) Kimiko Yamamoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Lipid–protein interactions: Lessons learned from stress

(2015) A.R. Battle et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Model for Probing Membrane-Cortex Adhesion by Micropipette Aspiration and Fluctuation Spectroscopy

(2015) Ricard Alert et al.   BIOPHYSICAL JOURNAL

Front-to-Rear Membrane Tension Gradient in Rapidly Moving Cells

(2015) Arnon D. Lieber et al.   BIOPHYSICAL JOURNAL

Transient Membrane Localization of SPV-1 Drives Cyclical Actomyosin Contractions in the C. elegans Spermatheca

(2015) Pei Yi Tan et al.   CURRENT BIOLOGY

Mechanobiology — chemical origin of membrane mechanical resistance and force-dependent signaling

(2015) Amy EM Beedle et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Microenvironment, tumor cell plasticity, and cancer

(2015) Eva Faurobert et al.   CURRENT OPINION IN ONCOLOGY

Membrane tension and membrane fusion

(2015) Michael M Kozlov et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Oligomerization but Not Membrane Bending Underlies the Function of Certain F-BAR Proteins in Cell Motility and Cytokinesis

(2015) Nathan A. McDonald et al.   DEVELOPMENTAL CELL

Caveolae protect endothelial cells from membrane rupture during increased cardiac output

(2015) Jade P.X. Cheng et al.   JOURNAL OF CELL BIOLOGY

Caveolae - mechanosensitive membrane invaginations linked to actin filaments

(2015) A. Echarri et al.   JOURNAL OF CELL SCIENCE

Membrane curvature at a glance

(2015) H. T. McMahon et al.   JOURNAL OF CELL SCIENCE

F-BAR family proteins, emerging regulators for cell membrane dynamic changes—from structure to human diseases

(2015) Suxuan Liu et al.   Journal of Hematology & Oncology

Membrane tension and cytoskeleton organization in cell motility

(2015) Pierre Sens et al.   JOURNAL OF PHYSICS-CONDENSED MATTER

Feedback regulation between plasma membrane tension and membrane-bending proteins organizes cell polarity during leading edge formation

(2015) Kazuya Tsujita et al.   NATURE CELL BIOLOGY

Membrane curvature enables N-Ras lipid anchor sorting to liquid-ordered membrane phases

(2015) Jannik Bruun Larsen et al.   Nature Chemical Biology

Hydraulic fracture during epithelial stretching

(2015) Laura Casares et al.   NATURE MATERIALS

Mechanically Activated Ion Channels

(2015) Sanjeev S. Ranade et al.   NEURON

Tubulation by Amphiphysin Requires Concentration-Dependent Switching from Wedging to Scaffolding

(2015) J. Mario Isas et al.   STRUCTURE

Membrane tension controls the assembly of curvature-generating proteins

(2015) Mijo Simunovic et al.   Nature Communications

Dynamic caveolae exclude bulk membrane proteins and are required for sorting of excess glycosphingolipids

(2015) Elena Shvets et al.   Nature Communications

Physical principles of membrane remodelling during cell mechanoadaptation

(2015) Anita Joanna Kosmalska et al.   Nature Communications

Intrinsically disordered proteins drive membrane curvature

(2015) David J. Busch et al.   Nature Communications

Membrane tension and peripheral protein density mediate membrane shape transitions

(2015) Zheng Shi et al.   Nature Communications

Target of Rapamycin Complex 2 regulates cell growth via Myc in Drosophila

(2015) Ying Kuo et al.   Scientific Reports

Mechanical sensitivity of Piezo1 ion channels can be tuned by cellular membrane tension

(2015) Amanda H Lewis et al.   eLife

Caveolae and cancer: A new mechanical perspective

(2015) Christophe Lamaze et al.   Biomedical Journal

Membrane Curvature Sensing by Amphipathic Helices Is Modulated by the Surrounding Protein Backbone

(2015) Christine M. Doucet et al.   PLoS One

Stresses at the Cell Surface during Animal Cell Morphogenesis

(2014) Andrew G. Clark et al.   CURRENT BIOLOGY

ERM proteins at a glance

(2014) Andrea I. McClatchey   JOURNAL OF CELL SCIENCE

The force-from-lipid (FFL) principle of mechanosensitivity, at large and in elements

(2014) Jinfeng Teng et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Dynamic Shaping of Cellular Membranes by Phospholipids and Membrane-Deforming Proteins

(2014) Shiro Suetsugu et al.   PHYSIOLOGICAL REVIEWS

Computational Estimates of Membrane Flow and Tension Gradient in Motile Cells

(2014) Ben Fogelson et al.   PLoS One

Force Transduction and Lipid Binding in MscL: A Continuum-Molecular Approach

(2014) Juan M. Vanegas et al.   PLoS One

Lipid Clustering Correlates with Membrane Curvature as Revealed by Molecular Simulations of Complex Lipid Bilayers

(2014) Heidi Koldsø et al.   PLoS Computational Biology

Dynamic recruitment of the curvature-sensitive protein ArhGAP44 to nanoscale membrane deformations limits exploratory filopodia initiation in neurons

(2014) Milos Galic et al.   eLife

Computer simulations of lipid membrane domains

(2013) W.F. Drew Bennett et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Unexpected Membrane Dynamics Unveiled by Membrane Nanotube Extrusion

(2013) Clément Campillo et al.   BIOPHYSICAL JOURNAL

Protein-Mediated Transformation of Lipid Vesicles into Tubular Networks

(2013) Mijo Simunovic et al.   BIOPHYSICAL JOURNAL

Cellular Pressure and Volume Regulation and Implications for Cell Mechanics

(2013) Hongyuan Jiang et al.   BIOPHYSICAL JOURNAL

Role of caveolae in shear stress-mediated endothelium-dependent dilation in coronary arteries

(2013) Qiang Chai et al.   CARDIOVASCULAR RESEARCH

Membrane Tension in Rapidly Moving Cells Is Determined by Cytoskeletal Forces

(2013) Arnon D. Lieber et al.   CURRENT BIOLOGY

Consequences of membrane topography

(2013) Ingela Parmryd et al.   FEBS Journal

Endothelial cell and model membranes respond to shear stress by rapidly decreasing the order of their lipid phases

(2013) K. Yamamoto et al.   JOURNAL OF CELL SCIENCE

Mimicking the nanostructure of bone matrix to regenerate bone

(2013) Robert Kane et al.   Materials Today

Plasma membrane organization and function: moving past lipid rafts

(2013) Mary L. Kraft   MOLECULAR BIOLOGY OF THE CELL

Caveolae as plasma membrane sensors, protectors and organizers

(2013) Robert G. Parton et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Confined Bilayers Passively Regulate Shape and Stress

(2013) Margarita Staykova et al.   PHYSICAL REVIEW LETTERS

Membrane Sculpting by F-BAR Domains Studied by Molecular Dynamics Simulations

(2013) Hang Yu et al.   PLoS Computational Biology

Coarse-Grained Models for Protein-Cell Membrane Interactions

(2013) Ryan Bradley et al.   Polymers

Effect of membrane tension on the physical properties of DOPC lipid bilayer membrane

(2012) A. Srinivas Reddy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Membrane tension homeostasis of epithelial cells through surface area regulation in response to osmotic stress

(2012) Anna Pietuch et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Increasing Membrane Tension Decreases Miscibility Temperatures; an Experimental Demonstration via Micropipette Aspiration

(2012) Thomas Portet et al.   BIOPHYSICAL JOURNAL

Nonlinear Sorting, Curvature Generation, and Crowding of Endophilin N-BAR on Tubular Membranes

(2012) Chen Zhu et al.   BIOPHYSICAL JOURNAL

Phase Behavior of Lipid Bilayers under Tension

(2012) Mark J. Uline et al.   BIOPHYSICAL JOURNAL

Membrane Tension Maintains Cell Polarity by Confining Signals to the Leading Edge during Neutrophil Migration

(2012) Andrew R. Houk et al.   CELL

Curvature Sorting of Peripheral Proteins on Solid-Supported Wavy Membranes

(2012) Wan-Ting Hsieh et al.   LANGMUIR

External push and internal pull forces recruit curvature-sensing N-BAR domain proteins to the plasma membrane

(2012) Milos Galic et al.   NATURE CELL BIOLOGY

Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis

(2012) Doris Berchtold et al.   NATURE CELL BIOLOGY

Stressing caveolae new role in cell mechanics

(2012) Pierre Nassoy et al.   TRENDS IN CELL BIOLOGY

Mechanical feedback between membrane tension and dynamics

(2012) Nils C. Gauthier et al.   TRENDS IN CELL BIOLOGY

Use the force: membrane tension as an organizer of cell shape and motility

(2012) Alba Diz-Muñoz et al.   TRENDS IN CELL BIOLOGY

Mechanisms of Membrane Curvature Sensing

(2011) Bruno Antonny   Annual Review of Biochemistry

Thermodynamics and Mechanics of Membrane Curvature Generation and Sensing by Proteins and Lipids

(2011) Tobias Baumgart et al.   Annual Review of Physical Chemistry

Cells Respond to Mechanical Stress by Rapid Disassembly of Caveolae

(2011) Bidisha Sinha et al.   CELL

Cell motility: the integrating role of the plasma membrane

(2011) Kinneret Keren   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

On the role of membrane anisotropy and BAR proteins in the stability of tubular membrane structures

(2011) Doron Kabaso et al.   JOURNAL OF BIOMECHANICS

Caveolae respond to cell stretch and contribute to stretch-induced signaling

(2011) O. L. Gervasio et al.   JOURNAL OF CELL SCIENCE

ARF1 controls proliferation of breast cancer cells by regulating the retinoblastoma protein

(2011) P-L Boulay et al.   ONCOGENE

Mechanics of surface area regulation in cells examined with confined lipid membranes

(2011) M. Staykova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Shear rheology of lipid monolayers and insights on membrane fluidity

(2011) G. Espinosa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nature of curvature coupling of amphiphysin with membranes depends on its bound density

(2011) B. Sorre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Temporary increase in plasma membrane tension coordinates the activation of exocytosis and contraction during cell spreading

(2011) N. C. Gauthier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane-mediated interactions between circular particles in the strongly curved regime

(2011) Benedict J. Reynwar et al.   Soft Matter

Lateral phase separation in tense membranes

(2011) Tsutomu Hamada et al.   Soft Matter

Mechanosensitive Channels: What Can They Do and How Do They Do It?

(2011) Elizabeth S. Haswell et al.   STRUCTURE

Hierarchical mesoscale domain organization of the plasma membrane

(2011) Akihiro Kusumi et al.   TRENDS IN BIOCHEMICAL SCIENCES

Curvature-Driven Lipid Sorting in Biomembranes

(2011) A. Callan-Jones et al.   Cold Spring Harbor Perspectives in Biology

Examining the Role of Mechanosensitive Ion Channels in Pressure Mechanotransduction in Rat Bladder Urothelial Cells

(2010) Shawn M. Olsen et al.   ANNALS OF BIOMEDICAL ENGINEERING

The plasma membrane plays a central role in cells response to mechanical stress

(2010) Sandra V. Verstraeten et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Endothelial Cell Membrane Sensitivity to Shear Stress is Lipid Domain Dependent

(2010) Tristan Tabouillot et al.   Cellular and Molecular Bioengineering

BAR domains, amphipathic helices and membrane-anchored proteins use the same mechanism to sense membrane curvature

(2010) K.L. Madsen et al.   FEBS LETTERS

Cytoskeleton–membrane interactions in membrane raft structure

(2009) Gurunadh R. Chichili et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The effects of mechanical forces on intestinal physiology and pathology

(2009) Christopher P. Gayer et al.   CELLULAR SIGNALLING

Amphipathic motifs in BAR domains are essential for membrane curvature sensing

(2009) Vikram K Bhatia et al.   EMBO JOURNAL

Amphipathic helices and membrane curvature

(2009) Guillaume Drin et al.   FEBS LETTERS

How curved membranes recruit amphipathic helices and protein anchoring motifs

(2009) Nikos S Hatzakis et al.   Nature Chemical Biology

Caveolae Act as Membrane Reserves Which Limit Mechanosensitive ICl,swell Channel Activation during Swelling in the Rat Ventricular Myocyte

(2009) Lukasz Kozera et al.   PLoS One

Morphology and interaction between lipid domains

(2009) T. S. Ursell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Geometric Cue for Protein Localization in a Bacterium

(2009) K. S. Ramamurthi et al.   SCIENCE

A unifying mechanism accounts for sensing of membrane curvature by BAR domains, amphipathic helices and membrane-anchored proteins

(2009) Vikram Kjøller Bhatia et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Membrane-induced bundling of actin filaments

(2008) Allen P. Liu et al.   Nature Physics