Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension

Unidirectional incorporation of a bacterial mechanosensitive channel into liposomal membranes

(2015) Takeshi Nomura et al.   FASEB JOURNAL

Architecture of the mammalian mechanosensitive Piezo1 channel

(2015) Jingpeng Ge et al.   NATURE

Activation of TRPV1 channels inhibits mechanosensitive Piezo channel activity by depleting membrane phosphoinositides

(2015) Istvan Borbiro et al.   Science Signaling

Piezo1 ion channel pore properties are dictated by C-terminal region

(2015) Bertrand Coste et al.   Nature Communications

Piezo1 in Smooth Muscle Cells Is Involved in Hypertension-Dependent Arterial Remodeling

(2015) Kevin Retailleau et al.   Cell Reports

Activation of TRPV1 channels inhibits mechanosensitive Piezo channel activity by depleting membrane phosphoinositides

(2015) Istvan Borbiro et al.   Science Signaling

Ionic Selectivity and Permeation Properties of Human PIEZO1 Channels

(2015) Radhakrishnan Gnanasambandam et al.   PLoS One

Energetics of gating MscS by membrane tension in azolectin liposomes and giant spheroplasts

(2014) Shaista Shaikh et al.   Channels

Gigaseal Mechanics: Creep of the Gigaseal under the Action of Pressure, Adhesion, and Voltage

(2014) Radomir I. Slavchov et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel

(2014) Stephen G. Brohawn et al.   NATURE

Piezo2 is required for Merkel-cell mechanotransduction

(2014) Seung-Hyun Woo et al.   NATURE

Extensible visualization and analysis for multidimensional images using Vaa3D

(2014) Hanchuan Peng et al.   Nature Protocols

Unique Interweaved Microtubule Scaffold Mediates Osmosensory Transduction via Physical Interaction with TRPV1

(2014) Masha Prager-Khoutorsky et al.   NEURON

Piezo2 channel conductance and localization domains in Merkel cells of rat whisker hair follicles

(2014) Ryo Ikeda et al.   NEUROSCIENCE LETTERS

Sensory mechanotransduction at membrane-matrix interfaces

(2014) Kate Poole et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

The evolutionary ‘tinkering’ of MscS-like channels: generation of structural and functional diversity

(2014) C. D. Cox et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

The force-from-lipid (FFL) principle of mechanosensitivity, at large and in elements

(2014) Jinfeng Teng et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Stretch-activated ion channel Piezo1 directs lineage choice in human neural stem cells

(2014) Medha M. Pathak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanosensitivity is mediated directly by the lipid membrane in TRAAK and TREK1 K+channels

(2014) Stephen G. Brohawn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Piezo1, a mechanically activated ion channel, is required for vascular development in mice

(2014) S. S. Ranade et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biophysical implications of lipid bilayer rheometry for mechanosensitive channels

(2014) N. Bavi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tuning Piezo ion channels to detect molecular-scale movements relevant for fine touch

(2014) Kate Poole et al.   Nature Communications

Slower Piezo1 Inactivation in Dehydrated Hereditary Stomatocytosis (Xerocytosis)

(2013) Sophie Demolombe et al.   BIOPHYSICAL JOURNAL

Human PIEZO1: Removing Inactivation

(2013) Chilman Bae et al.   BIOPHYSICAL JOURNAL

Xerocytosis is caused by mutations that alter the kinetics of the mechanosensitive channel PIEZO1

(2013) C. Bae et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gating the mechanical channel Piezo1

(2012) Philip A. Gottlieb et al.   Channels

The gating mechanism of the bacterial mechanosensitive channel MscL revealed by molecular dynamics simulations

(2012) Yasuyuki Sawada et al.   Channels

Identification and Regulation of a Molecular Module for Bleb-Based Cell Motility

(2012) Mehdi Goudarzi et al.   DEVELOPMENTAL CELL

Piezo proteins are pore-forming subunits of mechanically activated channels

(2012) Bertrand Coste et al.   NATURE

Differential effects of lipids and lyso-lipids on the mechanosensitivity of the mechanosensitive channels MscL and MscS

(2012) T. Nomura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Controlled delivery of bioactive molecules into live cells using the bacterial mechanosensitive channel MscL

(2012) Julia F. Doerner et al.   Nature Communications

Analyses of gating thermodynamics and effects of deletions in the mechanosensitive channel TREK-1

(2010) Grigory Maksaev et al.   Channels

Microtubule Dynamics, Mitotic Arrest, and Apoptosis: Drug-Induced Differential Effects of  III-Tubulin

(2010) P. P. Gan et al.   MOLECULAR CANCER THERAPEUTICS

Stretch-Activated Ion Channels: What Are They?

(2010) Frederick Sachs   PHYSIOLOGY

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

Biophysics and Structure of the Patch and the Gigaseal

(2009) Thomas M. Suchyna et al.   BIOPHYSICAL JOURNAL

Electromechanical coupling in the membranes of Shaker-transfected HEK cells

(2009) A. Beyder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell motility through plasma membrane blebbing

(2008) Oliver T. Fackler et al.   JOURNAL OF CELL BIOLOGY

Stretch-Activated Potassium Channels in Hypotonically Induced Blebs of Atrial Myocytes

(2008) Xuxia Liu et al.   JOURNAL OF MEMBRANE BIOLOGY

A short history of blebbing

(2008) G.T. CHARRAS   JOURNAL OF MICROSCOPY

Gating-associated conformational changes in the mechanosensitive channel MscL

(2008) K. Yoshimura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Life and Times of a Cellular Bleb

(2007) Guillaume T. Charras et al.   BIOPHYSICAL JOURNAL