EHD2 is a mechanotransducer connecting caveolae dynamics with gene transcription

EHD2 restrains dynamics of caveolae by an ATP-dependent, membrane-bound, open conformation

(2017) Maria Hoernke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Decreased Expression of EHD2 Promotes Tumor Metastasis and Indicates Poor Prognosis in Hepatocellular Carcinoma

(2016) Jinxia Liu et al.   DIGESTIVE DISEASES AND SCIENCES

Model for the architecture of caveolae based on a flexible, net-like assembly of Cavin1 and Caveolin discs

(2016) Miriam Stoeber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caveolae protect endothelial cells from membrane rupture during increased cardiac output

(2015) Jade P.X. Cheng et al.   JOURNAL OF CELL BIOLOGY

The caveolin–cavin system plays a conserved and critical role in mechanoprotection of skeletal muscle

(2015) Harriet P. Lo et al.   JOURNAL OF CELL BIOLOGY

Decreased expression and prognostic role of EHD2 in human breast carcinoma: correlation with E-cadherin

(2015) Yuhua Shi et al.   JOURNAL OF MOLECULAR HISTOLOGY

Mechanical induction of the tumorigenic β-catenin pathway by tumour growth pressure

(2015) María Elena Fernández-Sánchez et al.   NATURE

Role of EHD2 in migration and invasion of human breast cancer cells

(2015) Xiaojing Yang et al.   TUMOR BIOLOGY

Sumo and the cellular stress response

(2015) Jorrit M. Enserink   Cell Division

Caveolae and cancer: A new mechanical perspective

(2015) Christophe Lamaze et al.   Biomedical Journal

Structural Insights into the Organization of the Cavin Membrane Coat Complex

(2014) Oleksiy Kovtun et al.   DEVELOPMENTAL CELL

Caveolae regulate the nanoscale organization of the plasma membrane to remotely control Ras signaling

(2014) Nicholas Ariotti et al.   JOURNAL OF CELL BIOLOGY

Appreciating force and shape — the rise of mechanotransduction in cell biology

(2014) Thomas Iskratsch et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lattice light-sheet microscopy: Imaging molecules to embryos at high spatiotemporal resolution

(2014) Bi-Chang Chen et al.   SCIENCE

Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae

(2014) Yann Gambin et al.   eLife

Effects of EHD2 interference on migration of esophageal squamous cell carcinoma

(2013) Mei Li et al.   MEDICAL ONCOLOGY

Molecular Composition and Ultrastructure of the Caveolar Coat Complex

(2013) Alexander Ludwig et al.   PLOS BIOLOGY

EHD2 shuttles to the nucleus and represses transcription

(2012) Olga Pekar et al.   BIOCHEMICAL JOURNAL

Oligomers of the ATPase EHD2 confine caveolae to the plasma membrane through association with actin

(2012) Miriam Stoeber et al.   EMBO JOURNAL

Phosphocaveolin-1 is a mechanotransducer that induces caveola biogenesis via Egr1 transcriptional regulation

(2012) Bharat Joshi et al.   JOURNAL OF CELL BIOLOGY

EHD2 regulates caveolar dynamics via ATP-driven targeting and oligomerization

(2012) Björn Morén et al.   MOLECULAR BIOLOGY OF THE CELL

Stressing caveolae new role in cell mechanics

(2012) Pierre Nassoy et al.   TRENDS IN CELL BIOLOGY

Cells Respond to Mechanical Stress by Rapid Disassembly of Caveolae

(2011) Bidisha Sinha et al.   CELL

Caveolae respond to cell stretch and contribute to stretch-induced signaling

(2011) O. L. Gervasio et al.   JOURNAL OF CELL SCIENCE

Balancing forces: architectural control of mechanotransduction

(2011) Christopher C. DuFort et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Caveolin-1 in tumor progression: the good, the bad and the ugly

(2008) Jacky G. Goetz et al.   CANCER AND METASTASIS REVIEWS