Lysine acetyltransferases and lysine deacetylases as targets for cardiovascular disease

Inflammation and its resolution in atherosclerosis: mediators and therapeutic opportunities

(2019) Magnus Bäck et al.   Nature Reviews Cardiology

Sensing and Transmitting Intracellular Amino Acid Signals through Reversible Lysine Aminoacylations

(2018) Xia-Di He et al.   Cell Metabolism

Thymoquinone Attenuates Myocardial Ischemia/Reperfusion Injury Through Activation of SIRT1 Signaling

(2018) Yunyang Lu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Histone acetyltransferase 7 (KAT7)-dependent intragenic histone acetylation regulates endothelial cell gene regulation

(2018) Matthew S. Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sirtuin 1 regulates pulmonary artery smooth muscle cell proliferation

(2018) Giada Zurlo et al.   JOURNAL OF HYPERTENSION

HDAC1 localizes to the mitochondria of cardiac myocytes and contributes to early cardiac reperfusion injury

(2018) Daniel J. Herr et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

HDAC inhibition helps post-MI healing by modulating macrophage polarization

(2018) Denise Kimbrough et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Intracellular Crotonyl-CoA Stimulates Transcription through p300-Catalyzed Histone Crotonylation

(2018) Benjamin R. Sabari et al.   MOLECULAR CELL

Inhibition of HDAC6 Activity Alleviates Myocardial Ischemia/Reperfusion Injury in Diabetic Rats: Potential Role of Peroxiredoxin 1 Acetylation and Redox Regulation

(2018) Yan Leng et al.   Oxidative Medicine and Cellular Longevity

Histone deacetylase activity governs diastolic dysfunction through a nongenomic mechanism

(2018) Mark Y. Jeong et al.   Science Translational Medicine

Mitochondrial Fission Is Required for Angiotensin II-Induced Cardiomyocyte Apoptosis Mediated by a Sirt1-p53 Signaling Pathway

(2018) Jia Qi et al.   Frontiers in Pharmacology

Epigenetic regulation of vascular NADPH oxidase expression and reactive oxygen species production by histone deacetylase-dependent mechanisms in experimental diabetes

(2018) Simona-Adriana Manea et al.   Redox Biology

Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation

(2018) Ulrike Bruning et al.   Cell Metabolism

Inhibition of Histone Deacetylases Induces K+ Channel Remodeling and Action Potential Prolongation in HL-1 Atrial Cardiomyocytes

(2018) Patrick Lugenbiel et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Treatment of ventricular arrhythmias: What's New?

(2018) Timothy M Markman et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Emerging Role of Histone Acetyltransferase in Stem Cells and Cancer

(2018) Daniela Trisciuoglio et al.   Stem Cells International

Interplay among H3K9-editing enzymes SUV39H1, JMJD2C and SRC-1 drives p66Shc transcription and vascular oxidative stress in obesity

(2017) Sarah Costantino et al.   EUROPEAN HEART JOURNAL

P6486The integration of AKI and an elevation in plasma level of high sensitivity cardiac troponin T after PCI predicted more major cardiovascular events in acute coronary syndrome patients

(2017) L. Luo et al.   EUROPEAN HEART JOURNAL

Chidamide in relapsed or refractory peripheral T cell lymphoma: a multicenter real-world study in China

(2017) Yuankai Shi et al.   Journal of Hematology & Oncology

New Aspects of Vascular Calcification: Histone Deacetylases and Beyond

(2017) Duk-Hwa Kwon et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

A novel role of cellular interactions in vascular calcification

(2017) Adham Sameer A. Bardeesi et al.   Journal of Translational Medicine

The Landscape of Histone Modifications in a High-Fat Diet-Induced Obese (DIO) Mouse Model

(2017) Litong Nie et al.   MOLECULAR & CELLULAR PROTEOMICS

Sirtuin 1 regulates cardiac electrical activity by deacetylating the cardiac sodium channel

(2017) Ajit Vikram et al.   NATURE MEDICINE

Sirtuin1-regulated lysine acetylation of p66Shc governs diabetes-induced vascular oxidative stress and endothelial dysfunction

(2017) Santosh Kumar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

VEGF amplifies transcription through ETS1 acetylation to enable angiogenesis

(2017) Jiahuan Chen et al.   Nature Communications

AMP-Activated Protein Kinase and Sirtuin 1 Coregulation of Cortactin Contributes to Endothelial FunctionHighlights

(2016) Tzu-Pin Shentu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Normalization of NAD+Redox Balance as a Therapy for Heart FailureClinical Perspective

(2016) Chi Fung Lee et al.   CIRCULATION

Aberrant DNA methylation in the pathogenesis of atherosclerosis

(2016) Zhang Hai et al.   CLINICA CHIMICA ACTA

Histone lysine crotonylation during acute kidney injury in mice

(2016) Olga Ruiz-Andres et al.   Disease Models & Mechanisms

NMNAT3 is involved in the protective effect of SIRT3 in Ang II-induced cardiac hypertrophy

(2016) Zhongbao Yue et al.   EXPERIMENTAL CELL RESEARCH

Histone deacetyltransferase inhibitors Trichostatin A and Mocetinostat differentially regulate MMP9, IL-18 and RECK expression and attenuate Angiotensin II-induced cardiac fibroblast migration and proliferation

(2016) Naveen K Somanna et al.   HYPERTENSION RESEARCH

Epigenetic factors MeCP2 and HDAC6 control α-tubulin acetylation in cardiac fibroblast proliferation and fibrosis

(2016) Hui Tao et al.   INFLAMMATION RESEARCH

SIRT1/Atg5/autophagy are involved in the antiatherosclerosis effects of ursolic acid

(2016) Qixiao Jiang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Dynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters

(2016) Afsaneh Goudarzi et al.   MOLECULAR CELL

P66Shc-SIRT1 Regulation of Oxidative Stress Protects Against Cardio-cerebral Vascular Disease

(2016) Xiangyi Kong et al.   MOLECULAR NEUROBIOLOGY

Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds

(2016) Michael S. Bonkowski et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Metabolic regulation of gene expression through histone acylations

(2016) Benjamin R. Sabari et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanisms and regulation of endothelial VEGF receptor signalling

(2016) Michael Simons et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Metabolomics-assisted proteomics identifies succinylation and SIRT5 as important regulators of cardiac function

(2016) Sushabhan Sadhukhan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of class I histone deacetylases blunts cardiac hypertrophy through TSC2-dependent mTOR repression

(2016) Cyndi R. Morales et al.   Science Signaling

MDM2 E3 ligase-mediated ubiquitination and degradation of HDAC1 in vascular calcification

(2016) Duk-Hwa Kwon et al.   Nature Communications

Inhibition of class I histone deacetylases blunts cardiac hypertrophy through TSC2-dependent mTOR repression

(2016) Cyndi R. Morales et al.   Science Signaling

Role of histone deacetylase 2 and its posttranslational modifications in cardiac hypertrophy

(2015) Gwang Hyeon Eom et al.   BMB Reports

SIRT1 protects against myocardial ischemia–reperfusion injury via activating eNOS in diabetic rats

(2015) Mingge Ding et al.   Cardiovascular Diabetology

Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic mice

(2015) Youfang Chen et al.   Cardiovascular Diabetology

Inhibition of Hypertrophy Is a Good Therapeutic Strategy in Ventricular Pressure Overload

(2015) G. G. Schiattarella et al.   CIRCULATION

Innate Immunity and the Failing Heart

(2015) Douglas L. Mann   CIRCULATION RESEARCH

Panobinostat for the Treatment of Multiple Myeloma

(2015) J. P. Laubach et al.   CLINICAL CANCER RESEARCH

Role of Histone Acetylation in Cell Cycle Regulation

(2015) Miglena Koprinarova et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Inhibition of myocardial reperfusion injury by ischemic postconditioning requires sirtuin 3-mediated deacetylation of cyclophilin D

(2015) T. Bochaton et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Characterization of the cardiac succinylome and its role in ischemia–reperfusion injury

(2015) Jennifer A. Boylston et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

SIRT3 Blocks Aging-Associated Tissue Fibrosis in Mice by Deacetylating and Activating Glycogen Synthase Kinase 3β

(2015) Nagalingam R. Sundaresan et al.   MOLECULAR AND CELLULAR BIOLOGY

SIRT5 Regulates both Cytosolic and Mitochondrial Protein Malonylation with Glycolysis as a Major Target

(2015) Yuya Nishida et al.   MOLECULAR CELL

Protein acetylation in metabolism — metabolites and cofactors

(2015) Keir J. Menzies et al.   Nature Reviews Endocrinology

Is AMPK the savior of the failing heart?

(2015) Ty T. Kim et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Histone Acetylation Enzymes Coordinate Metabolism and Gene Expression

(2015) Yuan Shen et al.   TRENDS IN PLANT SCIENCE

IGF-1 signaling in neonatal hypoxia-induced pulmonary hypertension: Role of epigenetic regulation

(2015) Qiwei Yang et al.   VASCULAR PHARMACOLOGY

Electrocardiographic effects of class 1 selective histone deacetylase inhibitor romidepsin

(2015) Philip T. Sager et al.   Cancer Medicine

 -Tubulin Acetylation Elevated in Metastatic and Basal-like Breast Cancer Cells Promotes Microtentacle Formation, Adhesion, and Invasive Migration

(2014) A. E. Boggs et al.   CANCER RESEARCH

Sirtuin 3 Deficiency Is Associated with Inhibited Mitochondrial Function and Pulmonary Arterial Hypertension in Rodents and Humans

(2014) Roxane Paulin et al.   Cell Metabolism

Sirtuin inhibitors as anticancer agents

(2014) Jing Hu et al.   Future Medicinal Chemistry

A protective role of ciglitazone in ox-LDL-induced rat microvascular endothelial cellsviamodulating PPARγ-dependent AMPK/eNOS pathway

(2014) Lei Xu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Aberrant protein acylation is a common observation in inborn errors of acyl-CoA metabolism

(2014) Olga Pougovkina et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Selective inhibition of class I but not class IIb histone deacetylases exerts cardiac protection from ischemia reperfusion

(2014) Sverre E. Aune et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Lysine Malonylation Is Elevated in Type 2 Diabetic Mouse Models and Enriched in Metabolic Associated Proteins

(2014) Yipeng Du et al.   MOLECULAR & CELLULAR PROTEOMICS

Human histone acetyltransferase 1 (Hat1) acetylates lysine 5 of histone H2A in vivo

(2014) Juliana I. Tafrova et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Acetylation dynamics and stoichiometry in Saccharomyces cerevisiae

(2014) B. T. Weinert et al.   Molecular Systems Biology

Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders

(2014) Katrina J. Falkenberg et al.   NATURE REVIEWS DRUG DISCOVERY

50 years of protein acetylation: from gene regulation to epigenetics, metabolism and beyond

(2014) Eric Verdin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The growing landscape of lysine acetylation links metabolism and cell signalling

(2014) Chunaram Choudhary et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Tubulin hyperacetylation is adaptive in cardiac proteotoxicity by promoting autophagy

(2014) Patrick M. McLendon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging roles of post-translational modifications in signal transduction and angiogenesis

(2014) Nader Rahimi et al.   PROTEOMICS

Inflammatory stimuli induce inhibitory S-nitrosylation of the deacetylase SIRT1 to increase acetylation and activation of p53 and p65

(2014) S. Shinozaki et al.   Science Signaling

QTc prolongation induced by targeted biotherapies used in clinical practice and under investigation: a comprehensive review

(2014) Marzia Locatelli et al.   Targeted Oncology

Reversible acetylation regulates vascular endothelial growth factor receptor-2 activity

(2014) Annalisa Zecchin et al.   Journal of Molecular Cell Biology

Zinc regulates iNOS-derived nitric oxide formation in endothelial cells

(2014) Miriam M. Cortese-Krott et al.   Redox Biology

Roles of histone deacetylation and AMP kinase in regulation of cardiomyocyte PGC-1α gene expression in hypoxia

(2013) Angela Ramjiawan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The sirtuin inhibitor cambinol impairs MAPK signaling, inhibits inflammatory and innate immune responses and protects from septic shock

(2013) Jérôme Lugrin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The pathogenesis of cardiac fibrosis

(2013) Ping Kong et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Activation of Histone Deacetylase-6 Induces Contractile Dysfunction Through Derailment of α-Tubulin Proteostasis in Experimental and Human Atrial Fibrillation

(2013) Deli Zhang et al.   CIRCULATION

Histone Deacetylase Inhibition Attenuates Transcriptional Activity of Mineralocorticoid Receptor Through Its Acetylation and Prevents Development of Hypertension

(2013) Hae-Ahm Lee et al.   CIRCULATION RESEARCH

Trichostatin A, an HDAC Class I/II Inhibitor, Promotes Pi-Induced Vascular Calcification Via Up-Regulation of the Expression of Alkaline Phosphatase

(2013) Takuya Azechi et al.   Journal of Atherosclerosis and Thrombosis

Widespread and Enzyme-independentNϵ-Acetylation andNϵ-Succinylation of Proteins in the Chemical Conditions of the Mitochondrial Matrix

(2013) Gregory R. Wagner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A pathway involving HDAC5, cFLIP and caspases regulates expression of the splicing regulator polypyrimidine tract binding protein in the heart

(2013) J. Ye et al.   JOURNAL OF CELL SCIENCE

Genetics and Genomics of Pulmonary Arterial Hypertension

(2013) Florent Soubrier et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

HDAC Inhibition Suppresses Cardiac Hypertrophy and Fibrosis in DOCA-Salt Hypertensive Rats via Regulation of HDAC6/HDAC8 Enzyme Activity

(2013) Hae Jin Kee et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli

(2013) Brian T. Weinert et al.   MOLECULAR CELL

SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways

(2013) Jeongsoon Park et al.   MOLECULAR CELL

Role of p300 in regulating neuronal nitric oxide synthase gene expression through nuclear factor-κB-mediated way in neuronal cells

(2013) Y. Li et al.   NEUROSCIENCE

Epigenetics of hypoxic pulmonary arterial hypertension following intrauterine growth retardation rat: epigenetics in PAH following IUGR

(2013) Xue-Feng Xu et al.   RESPIRATORY RESEARCH

Functional Lysine Modification by an Intrinsically Reactive Primary Glycolytic Metabolite

(2013) R. E. Moellering et al.   SCIENCE

HDAC-dependent ventricular remodeling

(2013) Min Xie et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Pulmonary artery smooth muscle cell proliferation and migration in fetal lambs acclimatized to high-altitude long-term hypoxia: role of histone acetylation

(2012) Qiwei Yang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Metabolic inflexibility and protein lysine acetylation in heart mitochondria of a chronic model of Type 1 diabetes

(2012) Shraddha S. Vadvalkar et al.   BIOCHEMICAL JOURNAL

Histone Deacetylation Inhibition in Pulmonary Hypertension

(2012) Lan Zhao et al.   CIRCULATION

Selective Class I Histone Deacetylase Inhibition Suppresses Hypoxia-Induced Cardiopulmonary Remodeling Through an Antiproliferative Mechanism

(2012) Maria A. Cavasin et al.   CIRCULATION RESEARCH

Enhanced Angiogenic and Cardiomyocyte Differentiation Capacity of Epigenetically Reprogrammed Mouse and Human Endothelial Progenitor Cells Augments Their Efficacy for Ischemic Myocardial Repair

(2012) Melissa A. Thal et al.   CIRCULATION RESEARCH

Gene Silencing of the Mitochondrial Adaptor p66 Shc Suppresses Vascular Hyperglycemic Memory in Diabetes

(2012) Francesco Paneni et al.   CIRCULATION RESEARCH

Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease

(2012) Nambirajan Govindarajan et al.   EMBO Molecular Medicine

Inhibition of Histone Deacetylase-induced Myocardial Repair Is Mediated by c-kit in Infarcted Hearts

(2012) Ling Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rationale for the Development of 2-Aminobenzamide Histone Deacetylase Inhibitors as Therapeutics for Friedreich Ataxia

(2012) Elisabetta Soragni et al.   JOURNAL OF CHILD NEUROLOGY

Anti-apoptotic function of the E2F transcription factor 4 (E2F4)/p130, a member of retinoblastoma gene family in cardiac myocytes

(2012) Dharmendra Dingar et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Dilated cardiomyopathy and mitochondrial dysfunction in Sirt1-deficient mice: A role for Sirt1-Mef2 in adult heart

(2012) A. Planavila et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Genética y arritmias: aplicaciones diagnósticas y pronósticas

(2012) Nicola Monteforte et al.   REVISTA ESPANOLA DE CARDIOLOGIA

Casein Kinase-2α1 Induces Hypertrophic Response by Phosphorylation of Histone Deacetylase 2 S394 and its Activation in the Heart

(2011) Gwang Hyeon Eom et al.   CIRCULATION

Class IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactin

(2011) David Kaluza et al.   EMBO JOURNAL

HDAC4 Protein Regulates HIF1α Protein Lysine Acetylation and Cancer Cell Response to Hypoxia

(2011) Hao Geng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Emergence of Fibroblasts with a Proinflammatory Epigenetically Altered Phenotype in Severe Hypoxic Pulmonary Hypertension

(2011) M. Li et al.   JOURNAL OF IMMUNOLOGY

The First Identification of Lysine Malonylation Substrates and Its Regulatory Enzyme

(2011) Chao Peng et al.   MOLECULAR & CELLULAR PROTEOMICS

HAT4, a Golgi Apparatus-Anchored B-Type Histone Acetyltransferase, Acetylates Free Histone H4 and Facilitates Chromatin Assembly

(2011) Xiaohan Yang et al.   MOLECULAR CELL

Progress and challenges in translating the biology of atherosclerosis

(2011) Peter Libby et al.   NATURE

Epigenetic modulation of the renal β-adrenergic–WNK4 pathway in salt-sensitive hypertension

(2011) ShengYu Mu et al.   NATURE MEDICINE

Mechanisms of disease: pulmonary arterial hypertension

(2011) Ralph T. Schermuly et al.   Nature Reviews Cardiology

Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing autophagy

(2011) D. J. Cao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sirt5 Is a NAD-Dependent Protein Lysine Demalonylase and Desuccinylase

(2011) J. Du et al.   SCIENCE

Antifibrotic activity of an inhibitor of histone deacetylases in DOCA-salt hypertensive rats

(2010) Abishek Iyer et al.   BRITISH JOURNAL OF PHARMACOLOGY

Lysine deacetylation in ischaemic preconditioning: the role of SIRT1

(2010) Sergiy M. Nadtochiy et al.   CARDIOVASCULAR RESEARCH

Protein Acetylation in the Cardiorenal Axis

(2010) Erik W. Bush et al.   CIRCULATION RESEARCH

Histone Deacetylase 7 Controls Endothelial Cell Growth Through Modulation of β-Catenin

(2010) Andriana Margariti et al.   CIRCULATION RESEARCH

Histone Deacetylase 3 Antagonizes Aspirin-Stimulated Endothelial Nitric Oxide Production by Reversing Aspirin-Induced Lysine Acetylation of Endothelial Nitric Oxide Synthase

(2010) Saet-Byel Jung et al.   CIRCULATION RESEARCH

Histone Deacetylases: Anti-Angiogenic Targets in Cancer Therapy

(2010) D. Mottet et al.   CURRENT CANCER DRUG TARGETS

High levels of glucose induce apoptosis in cardiomyocyte via epigenetic regulation of the insulin-like growth factor receptor

(2010) Xi-Yong Yu et al.   EXPERIMENTAL CELL RESEARCH

HDAC Inhibition Attenuates Inflammatory, Hypertrophic, and Hypertensive Responses in Spontaneously Hypertensive Rats

(2010) Jeffrey P. Cardinale et al.   HYPERTENSION

The Tale of Protein Lysine Acetylation in the Cytoplasm

(2010) Karin Sadoul et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Roles and Targets of Class I and IIa Histone Deacetylases in Cardiac Hypertrophy

(2010) Hae Jin Kee et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Sirt3-Mediated Deacetylation of Evolutionarily Conserved Lysine 122 Regulates MnSOD Activity in Response to Stress

(2010) Randa Tao et al.   MOLECULAR CELL

Calmodulin kinase II is required for angiotensin II-mediated vascular smooth muscle hypertrophy

(2009) Hui Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Abrogation of TGF-β1-induced fibroblast-myofibroblast differentiation by histone deacetylase inhibition

(2009) Weichao Guo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Role of Src Tyrosine Kinase in the Atherogenic Effects of the 12/15-Lipoxygenase Pathway in Vascular Smooth Muscle Cells

(2008) Marpadga A. Reddy et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Inhibition of class I histone deacetylase with an apicidin derivative prevents cardiac hypertrophy and failure

(2008) Pasquale Gallo et al.   CARDIOVASCULAR RESEARCH

Sirt7 Increases Stress Resistance of Cardiomyocytes and Prevents Apoptosis and Inflammatory Cardiomyopathy in Mice

(2008) Olesya Vakhrusheva et al.   CIRCULATION RESEARCH

Elevated plasma prostaglandins and acetylated histone in monocytes in Type 1 diabetes patients

(2008) S. S. H. Chen et al.   DIABETIC MEDICINE

Histone deacetylase inhibition reduces myocardial ischemia-reperfusion injury in mice

(2008) Anne Granger et al.   FASEB JOURNAL

Transgenic Overexpression of Hdac3 in the Heart Produces Increased Postnatal Cardiac Myocyte Proliferation but Does Not Induce Hypertrophy

(2008) Chinmay M. Trivedi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone-deacetylase inhibition reverses atrial arrhythmia inducibility and fibrosis in cardiac hypertrophy independent of angiotensin

(2008) Fang Liu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Lysine Acetylation: Codified Crosstalk with Other Posttranslational Modifications

(2008) Xiang-Jiao Yang et al.   MOLECULAR CELL

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

(2008) I. H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA