Progress and challenges in translating the biology of atherosclerosis

Inhibition of IL-17A in atherosclerosis

(2011) Xiang Cheng et al.   ATHEROSCLEROSIS

9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response

(2011) Olivier Harismendy et al.   NATURE

National Institutes of Health Center for Human Immunology Conference, September 2009

(2010) Robert B. Nussenblatt et al.   Annals of the New York Academy of Sciences

Oxidized Low-Density Lipoprotein and Atherosclerosis

(2010) Daniel Steinberg et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Interleukin-17: friend or foe in atherosclerosis?

(2010) Soraya Taleb et al.   CURRENT OPINION IN LIPIDOLOGY

Atherosclerotic lesions in mouse and man: is it the same disease?

(2010) Jacob Fog Bentzon et al.   CURRENT OPINION IN LIPIDOLOGY

Association Between a Literature-Based Genetic Risk Score and Cardiovascular Events in Women

(2010) Nina P. Paynter   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Inhibition of T cell response to native low-density lipoprotein reduces atherosclerosis

(2010) Andreas Hermansson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

B cell depletion reduces the development of atherosclerosis in mice

(2010) Hafid Ait-Oufella et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Vascular Biology of Atherosclerosis and Imaging Targets

(2010) P. Libby et al.   JOURNAL OF NUCLEAR MEDICINE

Fibrates in CVD: a step towards personalised medicine

(2010) Bart Staels   LANCET

Effects of fibrates on cardiovascular outcomes: a systematic review and meta-analysis

(2010) Min Jun et al.   LANCET

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Safety of Anacetrapib in Patients with or at High Risk for Coronary Heart Disease

(2010) Christopher P. Cannon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effects of Combination Lipid Therapy in Type 2 Diabetes Mellitus

(2010)   NEW ENGLAND JOURNAL OF MEDICINE

Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation

(2010) Kristiina Rajamäki et al.   PLoS One

The LDL Receptor

(2009) Joseph L. Goldstein et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Attenuated atherosclerosis upon IL-17R signaling disruption in LDLr deficient mice

(2009) T. van Es et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Adaptive immunity and atherosclerosis

(2009) John Andersson et al.   CLINICAL IMMUNOLOGY

Cholesteryl ester transfer protein: at the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitors

(2009) M. J. Chapman et al.   EUROPEAN HEART JOURNAL

Loss of SOCS3 expression in T cells reveals a regulatory role for interleukin-17 in atherosclerosis

(2009) Soraya Taleb et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Testing the inflammatory hypothesis of atherothrombosis: scientific rationale for the cardiovascular inflammation reduction trial (CIRT)

(2009) PAUL M. RIDKER   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: a prospective study of the JUPITER trial

(2009) Paul M Ridker et al.   LANCET

Update on strategies to increase HDL quantity and function

(2009) Danielle Duffy et al.   Nature Reviews Cardiology

Vaccination against atherosclerosis? Induction of atheroprotective immunity

(2009) Göran K. Hansson et al.   Seminars in Immunopathology

Nicotinic Acid, Alone and in Combinations, for Reduction of Cardiovascular Risk

(2008) B. Greg Brown et al.   AMERICAN JOURNAL OF CARDIOLOGY

HDL Remodeling During the Acute Phase Response

(2008) Anisa Jahangiri et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

HDL, ABC Transporters, and Cholesterol Efflux: Implications for the Treatment of Atherosclerosis

(2008) Alan R. Tall et al.   Cell Metabolism

Effects of the Direct Lipoprotein-Associated Phospholipase A 2 Inhibitor Darapladib on Human Coronary Atherosclerotic Plaque

(2008) Patrick W. Serruys et al.   CIRCULATION

Repeated Replication and a Prospective Meta-Analysis of the Association Between Chromosome 9p21.3 and Coronary Artery Disease

(2008) Heribert Schunkert et al.   CIRCULATION

Toll-Like Receptor 2 Mediates Apolipoprotein CIII–Induced Monocyte Activation: Retracted

(2008) Akio Kawakami et al.   CIRCULATION RESEARCH

The metabolism and anti-atherogenic properties of HDL

(2008) Kerry-Anne Rye et al.   JOURNAL OF LIPID RESEARCH

Molecular and cellular mechanisms of the thrombotic complications of atherosclerosis

(2008) Peter Libby   JOURNAL OF LIPID RESEARCH

The LDL modification hypothesis of atherogenesis: an update

(2008) Daniel Steinberg   JOURNAL OF LIPID RESEARCH

Effects of succinobucol (AGI-1067) after an acute coronary syndrome: a randomised, double-blind, placebo-controlled trial

(2008) Jean-Claude Tardif et al.   LANCET

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

(2008) Sekar Kathiresan et al.   NATURE GENETICS

Effects of Intensive Glucose Lowering in Type 2 Diabetes

(2008)   NEW ENGLAND JOURNAL OF MEDICINE

Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reactive Protein

(2008) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Glucose Control and Vascular Complications in Veterans with Type 2 Diabetes

(2008) William Duckworth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pleiotropic effects of statin therapy: molecular mechanisms and clinical results

(2008) Chao-Yung Wang et al.   TRENDS IN MOLECULAR MEDICINE