Emerging roles of post-translational modifications in signal transduction and angiogenesis

Reversible acetylation regulates vascular endothelial growth factor receptor-2 activity

(2014) Annalisa Zecchin et al.   Journal of Molecular Cell Biology

Identification of PDCL3 as a Novel Chaperone Protein Involved in the Generation of Functional VEGF Receptor 2

(2013) Srimathi Srinivasan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reversible Acetylation Regulates Salt-inducible Kinase (SIK2) and Its Function in Autophagy

(2013) Fu-Chia Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recent molecular discoveries in angiogenesis and antiangiogenic therapies in cancer

(2013) Jonathan Welti et al.   JOURNAL OF CLINICAL INVESTIGATION

Tyrosine Phosphorylation of CD13 Regulates Inflammatory Cell-Cell Adhesion and Monocyte Trafficking

(2013) J. Subramani et al.   JOURNAL OF IMMUNOLOGY

Mitogenic and Oncogenic Stimulation of K433 Acetylation Promotes PKM2 Protein Kinase Activity and Nuclear Localization

(2013) Lei Lv et al.   MOLECULAR CELL

Signaling cross-talk in the resistance to HER family receptor targeted therapy

(2013) H Yamaguchi et al.   ONCOGENE

Lysine Methylation Promotes VEGFR-2 Activation and Angiogenesis

(2013) E. J. Hartsough et al.   Science Signaling

SCFβ-TRCPsuppresses angiogenesis and thyroid cancer cell migration by promoting ubiquitination and destruction of VEGF receptor 2

(2012) Shavali Shaik et al.   JOURNAL OF EXPERIMENTAL MEDICINE

VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd

(2012) Zuyue Sun et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Differential drug class-specific metastatic effects following treatment with a panel of angiogenesis inhibitors

(2012) Alicia S Chung et al.   JOURNAL OF PATHOLOGY

Modeling and predicting clinical efficacy for drugs targeting the tumor milieu

(2012) Mallika Singh et al.   NATURE BIOTECHNOLOGY

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

The Antifungal Drug Itraconazole Inhibits Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Glycosylation, Trafficking, and Signaling in Endothelial Cells

(2011) Benjamin A. Nacev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PEST Motif Serine and Tyrosine Phosphorylation Controls Vascular Endothelial Growth Factor Receptor 2 Stability and Downregulation

(2011) R. D. Meyer et al.   MOLECULAR AND CELLULAR BIOLOGY

Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylation negatively modulates EGFR-mediated ERK activation

(2011) Jung-Mao Hsu et al.   NATURE CELL BIOLOGY

Cell Signaling by Receptor Tyrosine Kinases

(2010) Mark A. Lemmon et al.   CELL

Uncovering the Human Methyltransferasome

(2010) Tanya C. Petrossian et al.   MOLECULAR & CELLULAR PROTEOMICS

Silencing or Fueling Metastasis with VEGF Inhibitors: Antiangiogenesis Revisited

(2009) Sonja Loges et al.   CANCER CELL

Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis

(2009) John M.L. Ebos et al.   CANCER CELL

Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis

(2009) Marta Pàez-Ribes et al.   CANCER CELL

The emerging field of dynamic lysine methylation of non-histone proteins

(2008) Jing Huang et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Acetylation of Conserved Lysines in the Catalytic Core of Cyclin-Dependent Kinase 9 Inhibits Kinase Activity and Regulates Transcription

(2008) A. Sabo et al.   MOLECULAR AND CELLULAR BIOLOGY

Lysine Acetylation: Codified Crosstalk with Other Posttranslational Modifications

(2008) Xiang-Jiao Yang et al.   MOLECULAR CELL

Arginine Methylation of FOXO Transcription Factors Inhibits Their Phosphorylation by Akt

(2008) Kazuyuki Yamagata et al.   MOLECULAR CELL

Arginine methylation regulates the p53 response

(2008) Martin Jansson et al.   NATURE CELL BIOLOGY

IQGAP1-Dependent Signaling Pathway Regulates Endothelial Cell Proliferation and Angiogenesis

(2008) Rosana D. Meyer et al.   PLoS One