Blockade of histone deacetylase 6 protects against cisplatin-induced acute kidney injury

Vinpocetine reduces diclofenac-induced acute kidney injury through inhibition of oxidative stress, apoptosis, cytokine production, and NF-κB activation in mice

(2017) Victor Fattori et al.   PHARMACOLOGICAL RESEARCH

Overexpression of HDAC6 induces pro-inflammatory responses by regulating ROS-MAPK-NF-κB/AP-1 signaling pathways in macrophages

(2016) Gi Soo Youn et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inhibition of HDAC3- and HDAC6-Promoted Survivin Expression Plays an Important Role in SAHA-Induced Autophagy and Viability Reduction in Breast Cancer Cells

(2016) Jane Ying-Chieh Lee et al.   Frontiers in Pharmacology

Inhibition of microtubule dynamics impedes repair of kidney ischemia/reperfusion injury and increases fibrosis

(2016) Sang Jun Han et al.   Scientific Reports

Innate Immune Pattern Recognition: A Cell Biological Perspective

(2015) Sky W. Brubaker et al.   Annual Review of Immunology

Valproate attenuates the proteinuria, podocyte and renal injury by facilitating autophagy and inactivation of NF-κB/iNOS signaling in diabetic rat

(2015) Sabbir Khan et al.   BIOCHIMIE

Epigenetics in acute kidney injury

(2015) Jinhua Tang et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

HDAC6 mediates HIV-1 tat-induced proinflammatory responses by regulating MAPK-NF-kappaB/AP-1 pathways in astrocytes

(2015) Gi Soo Youn et al.   GLIA

EGF Receptor Inhibition Alleviates Hyperuricemic Nephropathy

(2015) N. Liu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

NF-κB in inflammation and renal diseases

(2015) Haisong Zhang et al.   Cell and Bioscience

Involvement of transcription factor XBP1s in the resistance of HDAC6 inhibitor Tubastatin A to superoxidation via acetylation-mediated proteasomal degradation

(2014) Yue Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Histone deacetylase 4 selectively contributes to podocyte injury in diabetic nephropathy

(2014) Xiaojie Wang et al.   KIDNEY INTERNATIONAL

HDAC6 Deacetylase Activity Is Critical for Lipopolysaccharide-Induced Activation of Macrophages

(2014) Bing Yan et al.   PLoS One

Tubulin hyperacetylation is adaptive in cardiac proteotoxicity by promoting autophagy

(2014) Patrick M. McLendon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microtubule acetylation amplifies p38 kinase signalling and anti-inflammatory IL-10 production

(2014) Bin Wang et al.   Nature Communications

Pathophysiology of Cisplatin-Induced Acute Kidney Injury

(2014) Abdullah Ozkok et al.   Biomed Research International

Histone deacetylase 6 plays a role as a distinct regulator of diverse cellular processes

(2012) Yingxiu Li et al.   FEBS Journal

Autophagy protects proximal tubular cells from injury and apoptosis

(2012) Gur P. Kaushal   KIDNEY INTERNATIONAL

Autophagy in proximal tubules protects against acute kidney injury

(2012) Man Jiang et al.   KIDNEY INTERNATIONAL

X-Box Binding Protein 1 Is Essential for the Anti-Oxidant Defense and Cell Survival in the Retinal Pigment Epithelium

(2012) Yimin Zhong et al.   PLoS One

HDAC inhibitors in cancer biology: emerging mechanisms and clinical applications

(2011) Omar Khan et al.   IMMUNOLOGY AND CELL BIOLOGY

HDAC6 regulates aggresome-autophagy degradation pathway of α-synuclein in response to MPP+-induced stress

(2011) Min Su et al.   JOURNAL OF NEUROCHEMISTRY

HDAC6 α-tubulin deacetylase: A potential therapeutic target in neurodegenerative diseases

(2011) Guoyi Li et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

A Pathway for the Control of Anoikis Sensitivity by E-Cadherin and Epithelial-to-Mesenchymal Transition

(2011) S. Kumar et al.   MOLECULAR AND CELLULAR BIOLOGY

The HTLV-1 Tax protein inhibits formation of stress granules by interacting with histone deacetylase 6

(2011) S Legros et al.   ONCOGENE

Clostridium difficileToxin A Decreases Acetylation of Tubulin, Leading to Microtubule Depolymerization through Activation of Histone Deacetylase 6, and This Mediates Acute Inflammation

(2010) Hyo Jung Nam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of HDAC6 in Cancer

(2010) Grace I. Aldana-Masangkay et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Post-translational modifications of microtubules

(2010) D. Wloga et al.   JOURNAL OF CELL SCIENCE

Rational Design and Simple Chemistry Yield a Superior, Neuroprotective HDAC6 Inhibitor, Tubastatin A

(2010) Kyle V. Butler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NF- B in Renal Inflammation

(2010) A. B. Sanz et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Low-dose paclitaxel ameliorates renal fibrosis in rat UUO model by inhibition of TGF-β/Smad activity

(2010) Dongshan Zhang et al.   LABORATORY INVESTIGATION

Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury

(2010) Li Yang et al.   NATURE MEDICINE

Targeting X box-binding protein-1 (XBP1) enhances sensitivity of glioma cells to oxidative stress

(2010) Y. Liu et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

TWEAK Activates the Non-Canonical NFκB Pathway in Murine Renal Tubular Cells: Modulation of CCL21

(2010) Ana B. Sanz et al.   PLoS One

The cell-cell adhesion molecule E-cadherin

(2008) F. van Roy et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Genistein protects the kidney from cisplatin-induced injury

(2008) Mi Jeong Sung et al.   KIDNEY INTERNATIONAL

Autophagy is cytoprotective during cisplatin injury of renal proximal tubular cells

(2008) Sudharsan Periyasamy-Thandavan et al.   KIDNEY INTERNATIONAL

HDAC6 is a specific deacetylase of peroxiredoxins and is involved in redox regulation

(2008) R. B. Parmigiani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA