Mitochondria-targeted antioxidants

Skin resistance to oxidative stress induced by resveratrol: From Nrf2 activation to GSH biosynthesis

(2015) J. Soeur et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondria-targeted antioxidant SkQT1 decreases trauma-induced neurological deficit in rat and prevents amyloid-β-induced impairment of long-term potentiation in rat hippocampal slices

(2015) Elisaveta E. Genrikhs et al.   JOURNAL OF DRUG TARGETING

Mitochondrial iron homeostasis and its dysfunctions in neurodegenerative disorders

(2015) Natalia P. Mena et al.   MITOCHONDRION

Neurodegeneration with inflammation is accompanied by accumulation of iron and ferritin in microglia and neurons

(2015) Maj Schneider Thomsen et al.   NEUROBIOLOGY OF DISEASE

Characterization of the Neuroprotective Potential of Derivatives of the Iron Chelating Drug Deferiprone

(2015) Pamela Maher et al.   NEUROCHEMICAL RESEARCH

Possible involvement of iron-induced oxidative insults in neurodegeneration

(2015) Takeshi Asano et al.   NEUROSCIENCE LETTERS

Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease

(2015) Brent J. Ryan et al.   TRENDS IN BIOCHEMICAL SCIENCES

Malondialdehyde-derived epitopes in human skin result from acute exposure to solar UV and occur in nonmelanoma skin cancer tissue

(2014) Joshua D. Williams et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Mitochondria-targeted antioxidant (MitoQ) ameliorates age-related arterial endothelial dysfunction in mice

(2014) Rachel A. Gioscia-Ryan et al.   JOURNAL OF PHYSIOLOGY-LONDON

Mitochondria-targeted antioxidant MitoQ ameliorates experimental mouse colitis by suppressing NLRP3 inflammasome-mediated inflammatory cytokines

(2013) Amarjargal Dashdorj et al.   BMC Medicine

Mitochondrial Dysfunction Indirectly Elevates ROS Production by the Endoplasmic Reticulum

(2013) Michael P. Murphy   Cell Metabolism

Comparing the effects of mitochondrial targeted and localized antioxidants with cellular antioxidants in human skin cells exposed to UVA and hydrogen peroxide

(2013) Anne O. Oyewole et al.   FASEB JOURNAL

Antioxidants as therapies: can we improve on nature?

(2013) Michael P. Murphy   FREE RADICAL BIOLOGY AND MEDICINE

Tiron protects against UVB-induced senescence-like characteristics in human dermal fibroblasts by the inhibition of superoxide anion production and glutathione depletion

(2012) Yong Fang et al.   AUSTRALASIAN JOURNAL OF DERMATOLOGY

Nrf2 links epidermal barrier function with antioxidant defense

(2012) Matthias Schäfer et al.   EMBO Molecular Medicine

The role of antioxidants in photoprotection: A critical review

(2012) Lucy Chen et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Oxidative genome damage and its repair: Implications in aging and neurodegenerative diseases

(2012) Muralidhar L. Hegde et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Small Molecule Modulators of Keap1-Nrf2-ARE Pathway as Potential Preventive and Therapeutic Agents

(2012) Sadagopan Magesh et al.   MEDICINAL RESEARCH REVIEWS

Stressed out mitochondria: The role of mitochondria in ageing and cancer focussing on strategies and opportunities in human skin

(2012) Asif S. Tulah et al.   MITOCHONDRION

Flavonoids as antioxidants in plants: Location and functional significance

(2012) Giovanni Agati et al.   PLANT SCIENCE

Curcumin induces stress response and hormetically modulates wound healing ability of human skin fibroblasts undergoing ageing in vitro

(2011) Dino Demirovic et al.   BIOGERONTOLOGY

Oral Azathioprine Leads to Higher Incorporation of 6-Thioguanine in DNA of Skin than Liver: The Protective Role of the Keap1/Nrf2/ARE Pathway

(2011) S. Kalra et al.   Cancer Prevention Research

Measurement of H2O2 within Living Drosophila during Aging Using a Ratiometric Mass Spectrometry Probe Targeted to the Mitochondrial Matrix

(2011) Helena M. Cochemé et al.   Cell Metabolism

Ultraviolet-radiation induced skin inflammation: dissecting the role of bioactive lipids

(2011) Anna Nicolaou et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Acceleration of UVB-induced photoageing in nrf2 gene-deficient mice

(2011) Ayako Hirota et al.   EXPERIMENTAL DERMATOLOGY

Investigating the role of melanin in UVA/UVB- and hydrogen peroxide-induced cellular and mitochondrial ROS production and mitochondrial DNA damage in human melanoma cells

(2011) Helen Swalwell et al.   FREE RADICAL BIOLOGY AND MEDICINE

Strategies to Target Mitochondria and Oxidative Stress by Antioxidants: Key Points and Perspectives

(2011) Marvin Edeas   PHARMACEUTICAL RESEARCH

DNA damage spectra induced by photosensitization

(2011) Bernd Epe   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Iron, oxidative stress and the example of solar ultraviolet A radiation

(2011) Asma Aroun et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2

(2010) Zoltan Ungvari et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Tomato paste rich in lycopene protects against cutaneous photodamage in humans in vivo: a randomized controlled trial

(2010) M. Rizwan et al.   BRITISH JOURNAL OF DERMATOLOGY

Antioxidants add protection to a broad-spectrum sunscreen

(2010) Y. Wu et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Using natural dietary sources of antioxidants to protect against ultraviolet and visible radiation-induced DNA damage: An investigation of human green tea ingestion

(2010) Helena Malhomme de la Roche et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C patients

(2010) Edward J. Gane et al.   LIVER INTERNATIONAL

A double-blind, placebo-controlled study to assess the mitochondria-targeted antioxidant MitoQ as a disease-modifying therapy in Parkinson's disease

(2010) Barry J. Snow et al.   MOVEMENT DISORDERS

MitoQ administration prevents endotoxin-induced cardiac dysfunction

(2009) G. S. Supinski et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Mitochondria-Targeted Antioxidant MitoQ 10 Improves Endothelial Function and Attenuates Cardiac Hypertrophy

(2009) Delyth Graham et al.   HYPERTENSION

Oxidative Inactivation of Mitochondrial Aconitase Results in Iron and H2O2-Mediated Neurotoxicity in Rat Primary Mesencephalic Cultures

(2009) David Cantu et al.   PLoS One

Maturation of Iron-Sulfur Proteins in Eukaryotes: Mechanisms, Connected Processes, and Diseases

(2008) Roland Lill et al.   Annual Review of Biochemistry

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

The mitochondria-targeted antioxidant MitoQ protects against organ damage in a lipopolysaccharide–peptidoglycan model of sepsis

(2008) Damon A. Lowes et al.   FREE RADICAL BIOLOGY AND MEDICINE

Translocation of iron from lysosomes into mitochondria is a key event during oxidative stress-induced hepatocellular injury

(2008) Akira Uchiyama et al.   HEPATOLOGY

Mitochondrial dysfunction and cellular stress progression after ultraviolet B irradiation in human keratinocytes

(2008) Mariela L. Paz et al.   PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE

Targeting Nrf2 with the triterpenoid CDDO- imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice

(2008) T. E. Sussan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE

Intracellular labile iron

(2007) William Breuer et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY