Inhibiting glucosylceramide synthase exacerbates cisplatin-induced acute kidney injury

Inhibition of ceramide de novo synthesis as a postischemic strategy to reduce myocardial reperfusion injury

(2016) M. R. Reforgiato et al.   BASIC RESEARCH IN CARDIOLOGY

Ceramide channels and mitochondrial outer membrane permeability

(2016) Marco Colombini   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Glycosphingolipids and cell death: one aim, many ways

(2015) Carmen Garcia-Ruiz et al.   APOPTOSIS

Urinary kidney injury molecule-1 and monocyte chemotactic protein-1 are noninvasive biomarkers of cisplatin-induced nephrotoxicity in lung cancer patients

(2015) Haruka Shinke et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Sphingolipids and mitochondrial apoptosis

(2015) Gauri A. Patwardhan et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Ceramide as a Mediator of Non-Alcoholic Fatty Liver Disease and Associated Atherosclerosis

(2015) Takhar Kasumov et al.   PLoS One

Renal Glycosphingolipid Metabolism Is Dysfunctional in Lupus Nephritis

(2014) T. K. Nowling et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Sphingosine 1-Phosphate Receptor-1 Enhances Mitochondrial Function and Reduces Cisplatin-Induced Tubule Injury

(2014) A. Bajwa et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Epidermal Growth Factor Receptor Inhibition with Erlotinib Partially Prevents Cisplatin-Induced Nephrotoxicity in Rats

(2014) Yukihiro Wada et al.   PLoS One

Pathophysiology of Cisplatin-Induced Acute Kidney Injury

(2014) Abdullah Ozkok et al.   Biomed Research International

Urinary chemokine (C-C motif) ligand 2 (monocyte chemotactic protein-1) as a tubular injury marker for early detection of cisplatin-induced nephrotoxicity

(2013) Kumiko Nishihara et al.   BIOCHEMICAL PHARMACOLOGY

Conjunctive Therapy of Cisplatin With the OCT2 Inhibitor Cimetidine: Influence on Antitumor Efficacy and Systemic Clearance

(2013) J A Sprowl et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Systemic ceramide accumulation leads to severe and varied pathological consequences

(2013) Abdulfatah M. Alayoubi et al.   EMBO Molecular Medicine

Reducing FLI1 Levels in the MRL/lpr Lupus Mouse Model Impacts T Cell Function by Modulating Glycosphingolipid Metabolism

(2013) Erin Morris Richard et al.   PLoS One

Suppressed mitochondrial biogenesis in folic acid-induced acute kidney injury and early fibrosis

(2013) L. Jay Stallons et al.   TOXICOLOGY LETTERS

Ceramide-Based Therapeutics for the Treatment of Cancer

(2012) Brian M. Barth et al.   Anti-Cancer Agents in Medicinal Chemistry

Onco-Nephrology: Renal Toxicities of Chemotherapeutic Agents

(2012) M. A. Perazella   Clinical Journal of the American Society of Nephrology

Acute kidney injury

(2012) Rinaldo Bellomo et al.   LANCET

Targeting glucosylceramide synthase synergizes with C6-ceramide nanoliposomes to induce apoptosis in natural killer cell leukemia

(2012) Rebecca J. Watters et al.   LEUKEMIA & LYMPHOMA

D,L-Threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (DL-PDMP) increases endoplasmic reticulum stress, autophagy and apoptosis accompanying ceramide accumulation via ceramide synthase 5 protein expression in A549 cells

(2011) Mototeru Yamane et al.   BIOCHIMIE

Combinatorial therapies improve the therapeutic efficacy of nanoliposomal ceramide for pancreatic cancer

(2011) Yixing Jiang et al.   CANCER BIOLOGY & THERAPY

Ceramides as modulators of cellular and whole-body metabolism

(2011) Benjamin T. Bikman et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-33 Exacerbates Acute Kidney Injury

(2011) A. Akcay et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Accumulation of Long-Chain Glycosphingolipids during Aging Is Prevented by Caloric Restriction

(2011) María José Hernández-Corbacho et al.   PLoS One

Disruption of multidrug and toxin extrusion MATE1 potentiates cisplatin-induced nephrotoxicity

(2010) Takanori Nakamura et al.   BIOCHEMICAL PHARMACOLOGY

Regulated Secretion of Acid Sphingomyelinase

(2010) Russell W. Jenkins et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The BCL-2 Protein BAK Is Required for Long-chain Ceramide Generation during Apoptosis

(2010) Leah J. Siskind et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Group XV phospholipase A2, a lysosomal phospholipase A2

(2010) James A. Shayman et al.   PROGRESS IN LIPID RESEARCH

Mechanisms of Cisplatin Nephrotoxicity

(2010) Ronald P. Miller et al.   Toxins

Contribution of Organic Cation Transporter 2 (OCT2) to Cisplatin-Induced Nephrotoxicity

(2009) K K Filipski et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Role of glutathione S-transferase Pi in cisplatin-induced nephrotoxicity

(2008) Danyelle M. Townsend et al.   BIOMEDICINE & PHARMACOTHERAPY

A role for ceramide in driving cancer cell resistance to doxorubicin

(2008) Yong-Yu Liu et al.   FASEB JOURNAL

Remodeling of cellular cytoskeleton by the acid sphingomyelinase/ceramide pathway

(2008) Youssef H. Zeidan et al.   JOURNAL OF CELL BIOLOGY

Cisplatin nephrotoxicity: Mechanisms and renoprotective strategies

(2008) N. Pabla et al.   KIDNEY INTERNATIONAL

Suramin promotes recovery from renal ischemia/reperfusion injury in mice

(2008) Shougang Zhuang et al.   KIDNEY INTERNATIONAL

Principles of bioactive lipid signalling: lessons from sphingolipids

(2008) Yusuf A. Hannun et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Role of glycosphingolipid-enriched microdomains in innate immunity: Microdomain-dependent phagocytic cell functions

(2007) Fumiko Yoshizaki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS