Mechanisms of Cisplatin Nephrotoxicity

Autophagy delays apoptosis in renal tubular epithelial cells in cisplatin cytotoxicity

(2014) Gur P. Kaushal et al.   Autophagy

Organic Cation Transporter 2 Mediates Cisplatin-Induced Oto- and Nephrotoxicity and Is a Target for Protective Interventions

(2010) Giuliano Ciarimboli et al.   AMERICAN JOURNAL OF PATHOLOGY

Cisplatin induces apoptosis through the ERK–p66shc pathway in renal proximal tubule cells

(2010) Jeb S. Clark et al.   CANCER LETTERS

Influence of Oct1/Oct2-Deficiency on Cisplatin-Induced Changes in Urinary N-Acetyl- -D-Glucosaminidase

(2010) R. M. Franke et al.   CLINICAL CANCER RESEARCH

Urinary parameters predictive of cisplatin-induced acute renal injury in dogs

(2010) J. Eric McDuffie et al.   CYTOKINE

Endogenous IL-10 Attenuates Cisplatin Nephrotoxicity: Role of Dendritic Cells

(2010) R. K. Tadagavadi et al.   JOURNAL OF IMMUNOLOGY

ATF3-Mediated Epigenetic Regulation Protects against Acute Kidney Injury

(2010) H. F. Li et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

CD4+CD25+ regulatory T cells attenuate cisplatin-induced nephrotoxicity in mice

(2010) Hyojung Lee et al.   KIDNEY INTERNATIONAL

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE

The role of Toll-like receptors in renal diseases

(2010) Anna Gluba et al.   Nature Reviews Nephrology

Loss of p53 causes mitochondrial DNA depletion and altered mitochondrial reactive oxygen species homeostasis

(2009) Maria A. Lebedeva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Rosiglitazone synergizes anticancer activity of cisplatin and reduces its nephrotoxicity in 7, 12-dimethyl benz{a}anthracene (DMBA) induced breast cancer rats

(2009) Kulbhushan Tikoo et al.   BMC CANCER

Contribution of Organic Cation Transporter 2 (OCT2) to Cisplatin-Induced Nephrotoxicity

(2009) K K Filipski et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Toll-like receptor 9 inhibition confers protection from liver ischemia-reperfusion injury

(2009) Zubin M. Bamboat et al.   HEPATOLOGY

Low-dose cisplatin administration in murine cecal ligation and puncture prevents the systemic release of HMGB1 and attenuates lethality

(2009) P. Pan et al.   JOURNAL OF LEUKOCYTE BIOLOGY

siRNA Targeted to p53 Attenuates Ischemic and Cisplatin-Induced Acute Kidney Injury

(2009) B. A. Molitoris et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Renal Dendritic Cells Ameliorate Nephrotoxic Acute Kidney Injury

(2009) R. K. Tadagavadi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Regulatory T Cells Suppress Innate Immunity in Kidney Ischemia-Reperfusion Injury

(2009) G. R. Kinsey et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Foxp3+ regulatory T cells participate in repair of ischemic acute kidney injury

(2009) Maria Teresa Gandolfo et al.   KIDNEY INTERNATIONAL

Alpha-lipoic acid attenuates cisplatin-induced acute kidney injury in mice by suppressing renal inflammation

(2009) K. P. Kang et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Role of glutathione S-transferase Pi in cisplatin-induced nephrotoxicity

(2008) Danyelle M. Townsend et al.   BIOMEDICINE & PHARMACOTHERAPY

Prevention of cisplatin nephrotoxicity: state of the art and recommendations from the European Society of Clinical Pharmacy Special Interest Group on Cancer Care

(2008) Vincent Launay-Vacher et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Structural and Functional Basis for Therapeutic Modulation of p53 Signaling

(2008) E. A. Bassett et al.   CLINICAL CANCER RESEARCH

Interaction of Cisplatin with the Human Organic Cation Transporter 2

(2008) K. K. Filipski et al.   CLINICAL CANCER RESEARCH

Cisplatin primes murine peritoneal macrophages for enhanced expression of nitric oxide, proinflammatory cytokines, TLRs, transcription factors and activation of MAP kinases upon co-incubation with L929 cells

(2008) Puja Chauhan et al.   IMMUNOBIOLOGY

American Society of Clinical Oncology 2008 Clinical Practice Guideline Update: Use of Chemotherapy and Radiation Therapy Protectants

(2008) Martee L. Hensley et al.   JOURNAL OF CLINICAL ONCOLOGY

Induction of Apoptosis in Renal Tubular Cells by Histone Deacetylase Inhibitors, a Family of Anticancer Agents

(2008) G. Dong et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Cannabidiol Attenuates Cisplatin-Induced Nephrotoxicity by Decreasing Oxidative/Nitrosative Stress, Inflammation, and Cell Death

(2008) H. Pan et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Regulation and Pathological Role of p53 in Cisplatin Nephrotoxicity

(2008) M. Jiang et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

TLR4 Signaling Mediates Inflammation and Tissue Injury in Nephrotoxicity

(2008) B. Zhang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Autophagy is cytoprotective during cisplatin injury of renal proximal tubular cells

(2008) Sudharsan Periyasamy-Thandavan et al.   KIDNEY INTERNATIONAL

Cisplatin nephrotoxicity: Mechanisms and renoprotective strategies

(2008) N. Pabla et al.   KIDNEY INTERNATIONAL

The chemokine receptors CCR2 and CX3CR1 mediate monocyte/macrophage trafficking in kidney ischemia–reperfusion injury

(2008) Li Li et al.   KIDNEY INTERNATIONAL

Cancers take their Toll—the function and regulation of Toll-like receptors in cancer cells

(2008) R Chen et al.   ONCOGENE

TGF-  signaling in dendritic cells is a prerequisite for the control of autoimmune encephalomyelitis

(2008) Y. Laouar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA